DK170989A - Anvendelse af thromboxan a2 receptor-antagonist til hindring eller mindskning af uoenskede bivirkninger af protamin - Google Patents

Anvendelse af thromboxan a2 receptor-antagonist til hindring eller mindskning af uoenskede bivirkninger af protamin

Info

Publication number: DK170989A
Authority: DK; Denmark
Prior art keywords: receptor antagonist; protamin; thromboxan; prevent; side effects
Prior art date: 1988-04-11

Application number

DK170989A

Other languages

English (en)

Other versions

DK170989D0 (da

Inventor

Martin Lawrence Ogletree

William Anthony Schumacher

Gary James Grover

Lawrence Tim Friedhoff

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-11

Filing date

1989-04-10

Publication date

1989-10-12

1989-04-10 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1989-04-10 Publication of DK170989D0 publication Critical patent/DK170989D0/da

1989-10-12 Publication of DK170989A publication Critical patent/DK170989A/da

Links

239000000670 adrenergic alpha-2 receptor antagonist Substances 0.000 title 1
206010067484 Adverse reaction Diseases 0.000 abstract 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
102000007327 Protamines Human genes 0.000 abstract 1
108010007568 Protamines Proteins 0.000 abstract 1
229940123987 Thromboxane A2 receptor antagonist Drugs 0.000 abstract 1
230000006838 adverse reaction Effects 0.000 abstract 1
229960002897 heparin Drugs 0.000 abstract 1
229920000669 heparin Polymers 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
229940048914 protamine Drugs 0.000 abstract 1
208000002815 pulmonary hypertension Diseases 0.000 abstract 1
239000003769 thromboxane A2 receptor blocking agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)

DK170989A 1988-04-11 1989-04-10 Anvendelse af thromboxan a2 receptor-antagonist til hindring eller mindskning af uoenskede bivirkninger af protamin DK170989A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/179,694 US5066480A (en)	1988-04-11	1988-04-11	Method of preventing or reducing adverse reactions to protamine using a thromboxane a2 receptor antagonist

Publications (2)

Publication Number	Publication Date
DK170989D0 DK170989D0 (da)	1989-04-10
DK170989A true DK170989A (da)	1989-10-12

Family

ID=22657593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK170989A DK170989A (da)	1988-04-11	1989-04-10	Anvendelse af thromboxan a2 receptor-antagonist til hindring eller mindskning af uoenskede bivirkninger af protamin

Country Status (12)

Country	Link
US (1)	US5066480A (da)
EP (1)	EP0337697B1 (da)
JP (1)	JPH0296537A (da)
AT (1)	ATE92323T1 (da)
AU (1)	AU624370B2 (da)
CA (1)	CA1336953C (da)
DE (1)	DE68907976T2 (da)
DK (1)	DK170989A (da)
HU (1)	HU206261B (da)
IE (1)	IE63735B1 (da)
NZ (1)	NZ228491A (da)
ZA (1)	ZA892412B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69329333D1 (de) *	1992-03-20	2000-10-05	Cor Therapeutics Inc	Durch glykosylierung vermittelte hemmung des faktors x
US7356737B2 (en) *	2004-10-29	2008-04-08	International Business Machines Corporation	System, method and storage medium for testing a memory module
US9693998B2 (en)	2014-05-16	2017-07-04	Cumberland Pharmaceuticals, Inc.	Compositions and methods of treating cardiac fibrosis with ifetroban
US12161632B2 (en)	2014-05-16	2024-12-10	Cumberland Pharmaceuticals Inc.	Compositions and methods of treating cardiac fibrosis with ifetroban
AU2016285566A1 (en)	2015-06-30	2017-12-14	Cumberland Pharmaceuticals, Inc.	Thromboxane receptor antagonists in AERD/asthma
EP3454850B1 (en)	2016-05-11	2023-06-21	Cumberland Pharmaceuticals Inc.	Compositions and methods of treating muscular dystrophy with thromboxane-a2 receptor antagonists
JP7305197B2 (ja)	2017-11-29	2023-07-10	ヴァンダービルトユニバーシティー	腫瘍転移を阻害する方法
US11494695B2 (en)	2019-09-27	2022-11-08	Google Llc	Training neural networks to generate structured embeddings

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2809377A1 (de) *	1978-03-04	1979-09-13	Boehringer Mannheim Gmbh	Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3000377A1 (de) *	1980-01-07	1981-07-09	Boehringer Mannheim Gmbh, 6800 Mannheim	Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
ZA827529B (en) *	1981-11-09	1983-09-28	Squibb & Sons Inc	7-oxabicycloheptane and 7-oxabicycloheptene compounds
US4416896A (en) *	1982-05-17	1983-11-22	E. R. Squibb & Sons, Inc.	7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
EP0153858A3 (en) *	1984-02-29	1985-12-11	The Upjohn Company	The therapeutic use of prostaglandins
US4663336A (en) *	1985-07-01	1987-05-05	E. R. Squibb & Sons, Inc.	7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease

1988
- 1988-04-11 US US07/179,694 patent/US5066480A/en not_active Expired - Lifetime
1989
- 1989-03-29 NZ NZ228491A patent/NZ228491A/en unknown
- 1989-03-31 ZA ZA892412A patent/ZA892412B/xx unknown
- 1989-04-04 IE IE106189A patent/IE63735B1/en not_active IP Right Cessation
- 1989-04-10 DE DE89303511T patent/DE68907976T2/de not_active Expired - Fee Related
- 1989-04-10 DK DK170989A patent/DK170989A/da not_active Application Discontinuation
- 1989-04-10 AT AT89303511T patent/ATE92323T1/de not_active IP Right Cessation
- 1989-04-10 HU HU891710A patent/HU206261B/hu not_active IP Right Cessation
- 1989-04-10 EP EP89303511A patent/EP0337697B1/en not_active Expired - Lifetime
- 1989-04-11 CA CA000596348A patent/CA1336953C/en not_active Expired - Fee Related
- 1989-04-11 JP JP1092793A patent/JPH0296537A/ja active Pending
- 1989-04-11 AU AU32691/89A patent/AU624370B2/en not_active Ceased

Also Published As

Publication number	Publication date
IE63735B1 (en)	1995-06-14
DK170989D0 (da)	1989-04-10
HUT52372A (en)	1990-07-28
AU3269189A (en)	1989-10-12
CA1336953C (en)	1995-09-12
IE891061L (en)	1989-10-11
ATE92323T1 (de)	1993-08-15
NZ228491A (en)	1997-03-24
EP0337697A2 (en)	1989-10-18
ZA892412B (en)	1990-01-31
EP0337697B1 (en)	1993-08-04
DE68907976T2 (de)	1994-03-31
AU624370B2 (en)	1992-06-11
EP0337697A3 (en)	1990-08-16
JPH0296537A (ja)	1990-04-09
US5066480A (en)	1991-11-19
HU206261B (en)	1992-10-28
DE68907976D1 (de)	1993-09-09

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Legal Events

Date	Code	Title
1996-04-15	B1	Patent granted (law 1993)
2002-10-28	PBP	Patent lapsed
2005-02-07	AHS	Application shelved for other reasons than non-payment