DK1718593T3 - Stereoselektiv syntese af en 4,4-disubstitueret cyclohexanpropansyre - Google Patents

Stereoselektiv syntese af en 4,4-disubstitueret cyclohexanpropansyre

Info

Publication number
DK1718593T3
DK1718593T3 DK05708359T DK05708359T DK1718593T3 DK 1718593 T3 DK1718593 T3 DK 1718593T3 DK 05708359 T DK05708359 T DK 05708359T DK 05708359 T DK05708359 T DK 05708359T DK 1718593 T3 DK1718593 T3 DK 1718593T3
Authority
DK
Denmark
Prior art keywords
propanoic acid
stereoselective synthesis
disubstituted cyclohexane
cyclohexane propanoic
disubstituted
Prior art date
Application number
DK05708359T
Other languages
Danish (da)
English (en)
Inventor
Karel Marie Joseph Brands
Sarah Elizabeth Brewer
Antony John Davies
Ulf H Dolling
Deborah Camille Hammond
David Ross Lieberman
Jeremy Peter Scott
Original Assignee
Merck Sharp & Dohme
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme, Merck & Co Inc filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of DK1718593T3 publication Critical patent/DK1718593T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/16—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of hydrogen sulfide or its salts to unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK05708359T 2004-02-20 2005-02-16 Stereoselektiv syntese af en 4,4-disubstitueret cyclohexanpropansyre DK1718593T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54634304P 2004-02-20 2004-02-20
PCT/GB2005/000544 WO2005080309A1 (en) 2004-02-20 2005-02-16 Stereoselective synthesis of a 4,4-disubstituted cyclohexanepropanoic acid

Publications (1)

Publication Number Publication Date
DK1718593T3 true DK1718593T3 (da) 2007-10-22

Family

ID=34886259

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05708359T DK1718593T3 (da) 2004-02-20 2005-02-16 Stereoselektiv syntese af en 4,4-disubstitueret cyclohexanpropansyre

Country Status (17)

Country Link
US (1) US7411088B2 (de)
EP (1) EP1718593B1 (de)
JP (1) JP4719162B2 (de)
CN (1) CN100443458C (de)
AR (1) AR047666A1 (de)
AT (1) ATE368024T1 (de)
AU (1) AU2005214131B2 (de)
CA (1) CA2556348C (de)
CY (1) CY1108519T1 (de)
DE (1) DE602005001766T2 (de)
DK (1) DK1718593T3 (de)
ES (1) ES2290887T3 (de)
PL (1) PL1718593T3 (de)
PT (1) PT1718593E (de)
SI (1) SI1718593T1 (de)
TW (1) TWI352075B (de)
WO (1) WO2005080309A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0120347D0 (en) * 2001-08-21 2001-10-17 Merck Sharp & Dohme Therapeutic agents
CN111393253B (zh) * 2019-01-02 2022-11-29 江苏广域化学有限公司 一种含有反式取代环己基的化合物的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3601197A (en) * 1970-04-29 1971-08-24 Exxon Production Research Co Treatment of formations with aryl sulfonic acid
US4612254A (en) * 1985-03-07 1986-09-16 Occidental Chemical Corporation Aromatic carboxylic acid and metal-modified phenolic resins and methods of preparation
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
GB0108592D0 (en) * 2001-04-05 2001-05-23 Merck Sharp & Dohme Therapeutic agents
GB0108591D0 (en) * 2001-04-05 2001-05-23 Merck Sharp & Dohme Therapeutic agents
JP3711131B2 (ja) * 2001-08-21 2005-10-26 メルク シャープ エンド ドーム リミテッド 新規のシクロヘキシルスルホン
GB0120347D0 (en) * 2001-08-21 2001-10-17 Merck Sharp & Dohme Therapeutic agents
GB0218041D0 (en) * 2002-08-02 2002-09-11 Merck Sharp & Dohme Chemical process
GB0223039D0 (en) * 2002-10-04 2002-11-13 Merck Sharp & Dohme Therapeutic compounds
GB0318447D0 (en) * 2003-08-05 2003-09-10 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
CY1108519T1 (el) 2012-05-23
PL1718593T3 (pl) 2007-12-31
ATE368024T1 (de) 2007-08-15
CA2556348C (en) 2013-01-08
US20070225520A1 (en) 2007-09-27
EP1718593A1 (de) 2006-11-08
DE602005001766T2 (de) 2008-04-30
TW200602309A (en) 2006-01-16
PT1718593E (pt) 2007-10-17
ES2290887T3 (es) 2008-02-16
CN1918106A (zh) 2007-02-21
TWI352075B (en) 2011-11-11
EP1718593B1 (de) 2007-07-25
SI1718593T1 (sl) 2007-12-31
JP4719162B2 (ja) 2011-07-06
WO2005080309A8 (en) 2005-11-03
CN100443458C (zh) 2008-12-17
AR047666A1 (es) 2006-02-01
JP2007523141A (ja) 2007-08-16
CA2556348A1 (en) 2005-09-01
AU2005214131A1 (en) 2005-09-01
US7411088B2 (en) 2008-08-12
DE602005001766D1 (de) 2007-09-06
AU2005214131B2 (en) 2010-12-16
WO2005080309A1 (en) 2005-09-01

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