DK173685A - Ethanolaminderivater - Google Patents

Ethanolaminderivater Download PDF

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Publication number
DK173685A
DK173685A DK173685A DK173685A DK173685A DK 173685 A DK173685 A DK 173685A DK 173685 A DK173685 A DK 173685A DK 173685 A DK173685 A DK 173685A DK 173685 A DK173685 A DK 173685A
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DK
Denmark
Prior art keywords
safety
pouring stopper
pouring
stopper
adrenoreceptors
Prior art date
Application number
DK173685A
Other languages
English (en)
Other versions
DK173685D0 (da
Inventor
Ian Frederick Skidmore
Lawrence Henry Charles Lunts
Harry Finch
Alan Naylor
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848409908A external-priority patent/GB8409908D0/en
Priority claimed from GB848414858A external-priority patent/GB8414858D0/en
Priority claimed from GB848415761A external-priority patent/GB8415761D0/en
Priority claimed from GB848415762A external-priority patent/GB8415762D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DK173685D0 publication Critical patent/DK173685D0/da
Publication of DK173685A publication Critical patent/DK173685A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

Figure DK173685AD00021
hvor 3 R er hydrogen eller C^^-alkyl,
Ra er
Figure DK173685AD00022
„b og R er
Figure DK173685AD00023
eller hvor 4 R er ligekædet eller forgrenet C2_g_alkylen; og fysiologisk acceptable salte og solvater deraf.
Forbindelserne med den almene formel I har selektiv stimulerende virkning på f$2'adrenoreceptorer °9 er i$ær nyttige ved behandling af sygdomme, der er forbundet med reversibel luftvejsobstruktion såsom astma og kronisk bronkitis.
DK173685A 1984-04-17 1985-04-17 Ethanolaminderivater DK173685A (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB848409908A GB8409908D0 (en) 1984-04-17 1984-04-17 Chemical compounds
GB8409908 1984-04-17
GB848414858A GB8414858D0 (en) 1984-06-11 1984-06-11 Chemical compounds
GB8414858 1984-06-11
GB8415761 1984-06-20
GB848415761A GB8415761D0 (en) 1984-06-20 1984-06-20 Chemical compounds
GB8415762 1984-06-20
GB848415762A GB8415762D0 (en) 1984-06-20 1984-06-20 Chemical compounds

Publications (2)

Publication Number Publication Date
DK173685D0 DK173685D0 (da) 1985-04-17
DK173685A true DK173685A (da) 1985-10-18

Family

ID=27449545

Family Applications (1)

Application Number Title Priority Date Filing Date
DK173685A DK173685A (da) 1984-04-17 1985-04-17 Ethanolaminderivater

Country Status (4)

Country Link
EP (1) EP0162576B1 (da)
AU (1) AU581887B2 (da)
DE (1) DE3571808D1 (da)
DK (1) DK173685A (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8525321D0 (en) * 1985-10-15 1985-11-20 Glaxo Group Ltd Chemical compounds
GB8525483D0 (en) * 1985-10-16 1985-11-20 Glaxo Group Ltd Chemical compounds
GB8525484D0 (en) * 1985-10-16 1985-11-20 Glaxo Group Ltd Chemical compounds
EP0286242A3 (en) * 1987-03-12 1989-08-09 Glaxo Group Limited Ethanolamine derivates, processes for their preparation and pharmaceutical compositions containing them
GB8718938D0 (en) * 1987-08-11 1987-09-16 Glaxo Group Ltd Chemical compounds
IE883400L (en) * 1987-11-13 1989-05-13 Fuisz Technologies Ltd Phenethanolamine derivatives
NZ227365A (en) * 1987-12-18 1990-10-26 Glaxo Group Ltd Aromatic amino ethers and pharmaceutical compositions
ZA889405B (en) * 1987-12-18 1989-12-27 Glaxo Group Ltd Ethanolamine derivatives
ES2142771B1 (es) * 1998-09-28 2001-01-01 Vita Invest Sa Nuevos derivados de la 6-(4-fenil-butoxi) hexilamina y procedimiento para la obtencion de salmeterol.
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
JP2004526720A (ja) 2001-03-08 2004-09-02 グラクソ　グループ　リミテッド βアドレナリン受容体のアゴニスト
ATE381537T1 (de) 2001-03-22 2008-01-15 Glaxo Group Ltd Formanilid-derivative als beta2-adrenorezeptor- agonisten
ES2438985T3 (es) 2001-09-14 2014-01-21 Glaxo Group Limited Formulación de inhalación que comprende derivados de fenetanolamina para el tratamiento de enfermedades respiratorias
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
DE60320007T2 (de) 2002-10-28 2009-06-18 Glaxo Group Ltd., Greenford Phenthanolamin-Derivate zur Behandlung von Atemwegserkrankungen
GB0303396D0 (en) 2003-02-14 2003-03-19 Glaxo Group Ltd Medicinal compounds
GB0329182D0 (en) 2003-12-17 2004-01-21 Glaxo Group Ltd Chemical compounds
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
WO2008041914A1 (en) * 2006-10-06 2008-04-10 Astrazeneca Ab 5-(2-AMINO-L-HYDROXYETHYL)-8-HYDROXY-2-OXOQUINOLINE DERIVATIVES AND OTHER COMPOUNDS AS β2 -ADRENERGIC AGONISTS
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
JP2011524896A (ja) 2008-06-18 2011-09-08 アストラゼネカ・アクチエボラーグ 呼吸器障害の処置用のベータ２−アドレナリン受容体アゴニストとして作用するベンズオキサジノン誘導体
CN105968024A (zh) * 2013-06-19 2016-09-28 成都百途医药科技有限公司 一种奥拉西坦的合成方法
CN106397228A (zh) * 2016-08-29 2017-02-15 鲁南制药集团股份有限公司 一种沙美特罗碱基的制备方法
CN106478432A (zh) * 2016-08-29 2017-03-08 鲁南制药集团股份有限公司 一种昔奈酸沙美特罗的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE1899T1 (de) * 1979-06-16 1982-12-15 Beecham Group Plc Sekundaere amine, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
DE3513885A1 (de) * 1984-04-17 1985-10-17 Glaxo Group Ltd., London Phenethanolaminverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8426191D0 (en) * 1984-10-17 1984-11-21 Glaxo Holdings Ltd Chemical compounds
GB8525321D0 (en) * 1985-10-15 1985-11-20 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
DE3571808D1 (en) 1989-08-31
EP0162576A1 (en) 1985-11-27
DK173685D0 (da) 1985-04-17
AU581887B2 (en) 1989-03-09
AU4134685A (en) 1985-10-24
EP0162576B1 (en) 1989-07-26

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
B1 Patent granted (law 1993)