DK1745287T3 - Diagnostisering og monitorering af inflammatoriske sygdomme ved at måle komplementkomponenter på hvide blodlegemer - Google Patents

Diagnostisering og monitorering af inflammatoriske sygdomme ved at måle komplementkomponenter på hvide blodlegemer

Info

Publication number
DK1745287T3
DK1745287T3 DK05747945.3T DK05747945T DK1745287T3 DK 1745287 T3 DK1745287 T3 DK 1745287T3 DK 05747945 T DK05747945 T DK 05747945T DK 1745287 T3 DK1745287 T3 DK 1745287T3
Authority
DK
Denmark
Prior art keywords
monitoring
blood cells
inflammatory diseases
white blood
diagnosis
Prior art date
Application number
DK05747945.3T
Other languages
English (en)
Inventor
Joseph M Ahearn
Susan M Manzi
Chau-Ching Liu
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Application granted granted Critical
Publication of DK1745287T3 publication Critical patent/DK1745287T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/821—Chemistry: analytical and immunological testing involving complement factors or complement systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK05747945.3T 2004-05-11 2005-05-11 Diagnostisering og monitorering af inflammatoriske sygdomme ved at måle komplementkomponenter på hvide blodlegemer DK1745287T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57040604P 2004-05-11 2004-05-11
PCT/US2005/016436 WO2005111612A1 (en) 2004-05-11 2005-05-11 Diagnosing and monitoring inflammatory diseases by measuring complement components on white blood cells

Publications (1)

Publication Number Publication Date
DK1745287T3 true DK1745287T3 (da) 2011-01-24

Family

ID=35394276

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05747945.3T DK1745287T3 (da) 2004-05-11 2005-05-11 Diagnostisering og monitorering af inflammatoriske sygdomme ved at måle komplementkomponenter på hvide blodlegemer

Country Status (10)

Country Link
US (3) US7585640B2 (da)
EP (2) EP2214014A1 (da)
JP (1) JP2007537449A (da)
AT (1) ATE482393T1 (da)
AU (1) AU2005242719B2 (da)
CA (1) CA2564492C (da)
DE (1) DE602005023725D1 (da)
DK (1) DK1745287T3 (da)
ES (1) ES2353311T3 (da)
WO (1) WO2005111612A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7588905B2 (en) * 2003-04-16 2009-09-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Identification and monitoring of systemic lupus erythematosus
EP2214014A1 (en) * 2004-05-11 2010-08-04 The University of Pittsburgh Monitoring immunologic, hematologic and inflammatory diseases
JP5117336B2 (ja) * 2008-09-18 2013-01-16 国立大学法人 千葉大学 多発性硬化症またはｎｍｏの検査マーカーの測定方法
AU2009305575A1 (en) * 2008-10-16 2010-04-22 Cypress Bioscience, Inc. Method for diagnosis and monitoring of disease activity and response to treatment in systemic lupus erythematosus (SLE) and other autoimmune diseases
US8993343B2 (en) * 2009-01-28 2015-03-31 Korea Research Institute Of Bioscience And Biotechnology CD93 or use of soluble fragment thereof
EP2673644B1 (en) 2011-02-11 2016-02-10 Exagen Diagnostics, Inc. Methods for diagnosing systemic lupus erythematosus
US10413620B2 (en) 2012-08-17 2019-09-17 The Regents Of The University Of Colorado, A Body Corporate Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging
JP2015535212A (ja) 2012-08-17 2015-12-10 ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト 補体活性化を検出するための組成物および方法
US9863946B2 (en) 2013-02-08 2018-01-09 Allegheny-Singer Research Institute Cell-bound complement activation products as diagnostic biomarkers for pre-lupus
CN111965358A (zh) 2013-02-08 2020-11-20 阿勒格尼-辛格研究所 细胞结合的补体激活产物作为狼疮前期诊断性生物标志物
CN105229470B (zh) 2013-03-15 2018-11-27 艾克斯肯诊断股份有限公司 用于治疗和诊断系统性红斑狼疮的方法
RU2017107273A (ru) * 2014-08-08 2018-09-10 Аллегени-Сингер Рисерч Инститьют Антилимфоцитарные аутоантитела в качестве диагностических биомаркеров
WO2016038055A1 (en) * 2014-09-09 2016-03-17 Euro-Diagnostica Ab ANTIBODIES SPECIFIC FOR COMPLEMENT COMPONENT C4d AND USES THEREOF.
KR102328327B1 (ko) 2014-09-26 2021-11-22 소마로직, 인크. 심혈관 위험 사건 예측 및 이의 용도
EP3329278A4 (en) * 2015-07-31 2019-01-16 Allegheny-Singer Research Institute CELL-ASSOCIATED COMPLEMENT ACTIVATION PRODUCTS AS COMPARATIVE DIAGNOSTICS FOR ANTIBODY-BASED MEDICAMENTS
WO2018063914A1 (en) 2016-09-29 2018-04-05 Animantis, Llc Methods and apparatus for assessing immune system activity and therapeutic efficacy
JP7126668B2 (ja) * 2017-08-09 2022-08-29 国立大学法人金沢大学 膠原病判定方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8426467D0 (en) 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
EP0479909B1 (en) 1989-06-29 1996-10-30 Medarex, Inc. Bispecific reagents for aids therapy
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
AU8507191A (en) 1990-08-29 1992-03-30 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO1992020373A1 (en) 1991-05-14 1992-11-26 Repligen Corporation Heteroconjugate antibodies for treatment of hiv infection
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
CA2148219C (en) 1992-10-30 1998-12-29 Charles W. Rittershaus Measurement of total molecule in a sample and methods based thereon
JP3104197B2 (ja) * 1993-06-11 2000-10-30 ポーラ化成工業株式会社 補体レセプター発現量の測定法
JP4570872B2 (ja) * 2001-09-10 2010-10-27 ユニヴァーシティ オブ ピッツバーグ 全身性紅斑性狼瘡および強皮症の診断およびモニタリング方法
US8080382B2 (en) * 2003-06-13 2011-12-20 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Monitoring immunologic, hematologic and inflammatory diseases
EP2216650A1 (en) * 2004-04-09 2010-08-11 University of Pittsburgh Real time method of detecting acute inflammatory conditions
EP2214014A1 (en) * 2004-05-11 2010-08-04 The University of Pittsburgh Monitoring immunologic, hematologic and inflammatory diseases

Also Published As

Publication number Publication date
WO2005111612A1 (en) 2005-11-24
AU2005242719A1 (en) 2005-11-24
US20110275060A1 (en) 2011-11-10
EP1745287A4 (en) 2008-04-16
JP2007537449A (ja) 2007-12-20
US20070026387A1 (en) 2007-02-01
ATE482393T1 (de) 2010-10-15
CA2564492C (en) 2012-05-22
DE602005023725D1 (de) 2010-11-04
ES2353311T3 (es) 2011-03-01
EP1745287A1 (en) 2007-01-24
EP2214014A1 (en) 2010-08-04
CA2564492A1 (en) 2005-11-24
US7585640B2 (en) 2009-09-08
US20090298198A1 (en) 2009-12-03
EP1745287B1 (en) 2010-09-22
AU2005242719B2 (en) 2011-02-24

Similar Documents

Publication Publication Date Title
DK1635692T3 (da) Monitorering af immunologiske, hematologiske og inflammatoriske sygdomme
EP1745287A4 (en) DIAGNOSIS AND MONITORING OF INFLAMMATORY DISEASES BY MEASURING THE ADDITIONAL COMPONENTS OF LEUKOCYTES
WO2007062090A3 (en) Methods and compositions related to b cell assays
EA200970603A1 (ru) Антагонисты активин-actrii и их применения для повышения уровней эритроцитов
IS8637A (is) Blóðflögur úr stofnfrumum
DE602004032228D1 (de) Optischer sensor mit gewebeüberwucherungskompensation
ATE381334T1 (de) 2,5-substituiertetetrahydroisochinoline zur verwendung als 5-ht6 modulatoren
DK2848938T3 (da) Evaluering af effektiviteten af en behandling hos et individ baseret på st2- niveauer
DK3494882T3 (da) Indretning til overvågning af analytter
EP4061219A4 (en) ASSESSMENT SPEECH AUDIOMETRY
DK1604203T3 (da) Fremgangsmåde til direkte bestemmelse af individuelle methotrexatmeta-bolitter
BRPI0911857A2 (pt) elemento de conexão para componentes ortopédicos.
WO2009007649A3 (fr) Dispositif et procede d'identification et de determination de groupes sanguins
BRPI0622419A2 (pt) composições pesticidas e/ou herbicidas e métodos de utilização das mesmas.
ATE478335T1 (de) Verfahren in echtzeit zur erkennung von akuten entzündungszuständen
DK1817079T3 (da) Behandling af inflammationer
DE602007004570D1 (de) Verwendung von Nogo-C bei der Beurteilung von Herzversagen
AU2003284234A1 (en) Methods of assessing the risk of reproductive failure by measuring telomere length
FR2885726B1 (fr) Circuit amplificateur de detection pour la detection parallele de quatre niveaux de courant
DK1613772T3 (da) Fremgangsmåde til bestemmelse af tilstanden af jord
DK1907579T3 (da) Fremgangsmåde til diagnose af glioma ved at skelne mellem typerne progressive og denovo
DK1558929T3 (da) Kvantificering af stresseksponering
ITMI20040019A1 (it) Derivati isossazolici e loro impiego come inibitori della ciclossigenasi
WO2007075641A3 (en) Methods for assessing the pro-inflammatory immune health of an individual
TW200639381A (en) Low powerconsumed and small circuit area occupiedn temperature sensor