ATE478335T1 - Verfahren in echtzeit zur erkennung von akuten entzündungszuständen - Google Patents

Verfahren in echtzeit zur erkennung von akuten entzündungszuständen

Info

Publication number
ATE478335T1
ATE478335T1 AT05776689T AT05776689T ATE478335T1 AT E478335 T1 ATE478335 T1 AT E478335T1 AT 05776689 T AT05776689 T AT 05776689T AT 05776689 T AT05776689 T AT 05776689T AT E478335 T1 ATE478335 T1 AT E478335T1
Authority
AT
Austria
Prior art keywords
real
inflammatory conditions
acute inflammatory
time method
detecting acute
Prior art date
Application number
AT05776689T
Other languages
English (en)
Inventor
Joseph M Ahearn
Susan M Manzi
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Application granted granted Critical
Publication of ATE478335T1 publication Critical patent/ATE478335T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Rehabilitation Therapy (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Washing And Drying Of Tableware (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
AT05776689T 2004-04-09 2005-04-08 Verfahren in echtzeit zur erkennung von akuten entzündungszuständen ATE478335T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56098604P 2004-04-09 2004-04-09
US57962104P 2004-06-14 2004-06-14
PCT/US2005/011914 WO2005108988A2 (en) 2004-04-09 2005-04-08 Real time method of detecting acute inflammatory conditions

Publications (1)

Publication Number Publication Date
ATE478335T1 true ATE478335T1 (de) 2010-09-15

Family

ID=35320843

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05776689T ATE478335T1 (de) 2004-04-09 2005-04-08 Verfahren in echtzeit zur erkennung von akuten entzündungszuständen

Country Status (9)

Country Link
US (1) US7361517B2 (de)
EP (2) EP2216650A1 (de)
JP (1) JP2007532885A (de)
AT (1) ATE478335T1 (de)
AU (1) AU2005241415A1 (de)
CA (1) CA2561684A1 (de)
DE (1) DE602005023009D1 (de)
DK (1) DK1756571T3 (de)
WO (1) WO2005108988A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004232007B2 (en) * 2003-04-16 2009-10-22 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Identification and monitoring of systematic lupus erythematosus
DK1745287T3 (da) * 2004-05-11 2011-01-24 Univ Pittsburgh Diagnostisering og monitorering af inflammatoriske sygdomme ved at måle komplementkomponenter på hvide blodlegemer
US20090247454A1 (en) * 2004-09-29 2009-10-01 Mellitus, S.L. Method for detecting a predisposition to develop gestational diabetes mellitus and treatment for this disease
AU2009305575A1 (en) * 2008-10-16 2010-04-22 Cypress Bioscience, Inc. Method for diagnosis and monitoring of disease activity and response to treatment in systemic lupus erythematosus (SLE) and other autoimmune diseases
BRPI0920897A2 (pt) * 2008-11-24 2015-12-29 Corthera Inc prognóstico e prevenção de pré-eclampsia
US8940490B2 (en) 2010-11-29 2015-01-27 Novelmed Therapeutics, Inc. Neoantibodies for diagnosing tissue injury
WO2012109592A1 (en) 2011-02-11 2012-08-16 Exagen Diagnostics, Inc. Methods for diagnosing systemic lupus erythematosus
CA2877441A1 (en) 2012-07-02 2014-01-09 Medizinische Universitat Wien Complement split product c4d for the treatment of inflammatory conditions
RU2680270C2 (ru) * 2013-02-08 2019-02-19 Аллегени-Сингер Рисерч Инститьют Клеточно-связанные продукты активации комплемента в качестве диагностических биомаркеров волчанки в доклинической стадии
WO2014153232A2 (en) * 2013-03-14 2014-09-25 Organ-I, Inc. Methods and compositions for diagnosing preeclampsia
CN105229470B (zh) 2013-03-15 2018-11-27 艾克斯肯诊断股份有限公司 用于治疗和诊断系统性红斑狼疮的方法
WO2016023006A1 (en) * 2014-08-08 2016-02-11 Allegheny-Singer Research Institute Anti-lymphocyte autoantibodies as diagnostic biomarkers

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
JPS63172963A (ja) * 1986-11-14 1988-07-16 ロバート　エイ．レビン 生物学的粒子の検出方法
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
ES2096590T3 (es) 1989-06-29 1997-03-16 Medarex Inc Reactivos biespecificos para la terapia del sida.
WO1992000373A1 (en) 1990-06-29 1992-01-09 Biosource Genetics Corporation Melanin production by transformed microorganisms
ATE158021T1 (de) 1990-08-29 1997-09-15 Genpharm Int Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
JPH07509783A (ja) 1992-10-30 1995-10-26 ティー　セル　ダイアグノスティックス，インコーポレーテッド 試料中の全分子の測定及びそれに基づく方法
ATE407676T1 (de) * 2000-02-28 2008-09-15 Univ British Columbia Topoisomerasehemmern zur behandlung von chirurgischen verklebungen
AU2002323691C1 (en) * 2001-09-10 2009-03-05 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma
US20030158083A1 (en) * 2002-02-08 2003-08-21 The Procter & Gamble Company Method of effecting angiogenesis by modulating the function of a novel endothelia phosphatase
ES2342291T3 (es) * 2003-06-13 2010-07-05 University Of Pittsburgh Control de enfermedades inmunologicas, hematologicas e inflamatorias.

Also Published As

Publication number Publication date
EP1756571B1 (de) 2010-08-18
US7361517B2 (en) 2008-04-22
JP2007532885A (ja) 2007-11-15
US20050282234A1 (en) 2005-12-22
EP1756571A2 (de) 2007-02-28
CA2561684A1 (en) 2005-11-17
EP1756571A4 (de) 2008-05-07
DE602005023009D1 (de) 2010-09-30
WO2005108988A3 (en) 2006-05-18
DK1756571T3 (da) 2010-12-13
WO2005108988A2 (en) 2005-11-17
EP1756571B8 (de) 2010-10-13
EP2216650A1 (de) 2010-08-11
AU2005241415A1 (en) 2005-11-17

Similar Documents

Publication Publication Date Title
ATE493649T1 (de) Verfahren zur diagnose von polyzystischer nierenkrankheit
ATE478335T1 (de) Verfahren in echtzeit zur erkennung von akuten entzündungszuständen
ATE442592T1 (de) Detektion und/oder beobachtung von synuclein- assoziierten krankheiten
EP2930512A3 (de) Biomarker für Fettlebererkrankung und Verfahren zu deren Verwendung
ATE452343T1 (de) Verbesserte vitamin-d-messung
WO2007007129A3 (en) Diagnostic method for brain damage-related disorders
WO2005048823A3 (en) Modeling of systemic inflammatory response to infection
WO2006036744A3 (en) Methods for a global assay of coagulation and fibrinolysis
WO2006081521A3 (en) Methods for diagnosis and intervention of hepatic disorders
ATE550658T1 (de) Verfahren für den nachweis oder die diagnose neurodegenerativer erkrankungen oder leiden
WO2007134028A3 (en) Biomarkers for depression and methods using the same
ATE537445T1 (de) Screening-verfahren
EP1994172A4 (de) Verfahren zur diagnose und/oder vorhersage der entwicklung einer allergischen erkrankung und agentien zur behandlung und/oder vorbeugung davon
ATE354097T1 (de) Verfahren zur diagnose von leberfibrose.
EP1745287A4 (de) Diagnose und überwachung von entzündlichen krankheiten mittels messung der zusätzlichen komponenten von leukozyten
BRPI0511127A (pt) prouroguanilina e análogos sintéticos ou produtos da clivagem proteolìtica dela derivados, como agentes terapêuticos e de diagnósticos para doenças que envolvem a homeostasia de sal e/ou de lìquidos
ATE473448T1 (de) Verfahren zur diagnose von herz-kreislauf- krankheiten
ATE470862T1 (de) Vorrichtung und verfahren zur unterscheidung zwischen akuter und chronischer myokardial- nekrose bei symptomatischen patienten
ATE550668T1 (de) Verfahren zur identifizierung von patienten mit erhöhtem risiko für ein unerwünschtes herz- kreislauf-ereignis
ATE514948T1 (de) In vitro verfahren zur diagnose von neurodegenerativen erkrankungen
ATE520987T1 (de) Verfahren zum nachweis und/oder screening zur überwachung eines kolorektalkrebs in einem individuum
DE602006017058D1 (de) Verfahren zur stratifizierung von herzinsuffizienz
CA2575405A1 (en) Method for diagnosing liver fibrosis
WO2005071407A3 (en) Methods of diagnosing acute coronary syndrome by measuring urotensin ii
WO2006138219A3 (en) Methods of diagnosis / prognosis of inflammatory conditions

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties