DK176085D0 - 4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler - Google Patents

4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler

Info

Publication number: DK176085D0
Authority: DK; Denmark
Prior art keywords: tetrahydropyridines; nitrophenyl; different; medicines; procedures
Prior art date: 1984-04-19

Application number

DK176085A

Other languages

English (en)

Other versions

DK176085A (da

Inventor

Ulrich Rosentreter

Guenter Thomas

Andreas Knorr

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-04-19

Filing date

1985-04-18

Publication date

1985-04-18

1985-04-18 Application filed by Bayer Ag filed Critical Bayer Ag

1985-04-18 Publication of DK176085D0 publication Critical patent/DK176085D0/da

1985-10-20 Publication of DK176085A publication Critical patent/DK176085A/da

Links

-1 NITROPHENYL Chemical class 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000000034 method Methods 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
JQVRHFKESREDKO-UHFFFAOYSA-N 4-(2-nitrophenyl)-1,2,3,4-tetrahydropyridine Chemical class [O-][N+](=O)C1=CC=CC=C1C1C=CNCC1 JQVRHFKESREDKO-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
125000002560 nitrile group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229940124549 vasodilator Drugs 0.000 abstract 1
239000003071 vasodilator agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Plural Heterocyclic Compounds (AREA)

DK176085A 1984-04-19 1985-04-18 4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler DK176085A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19843414801 DE3414801A1 (de)	1984-04-19	1984-04-19	4-(nitrophenyl)-tetrahydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3414801		1984-04-19

Publications (2)

Publication Number	Publication Date
DK176085D0 true DK176085D0 (da)	1985-04-18
DK176085A DK176085A (da)	1985-10-20

Family

ID=6233988

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK176085A DK176085A (da)	1984-04-19	1985-04-18	4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler

Country Status (10)

Country	Link
US (1)	US4621093A (da)
EP (1)	EP0158956B1 (da)
JP (1)	JPS60233057A (da)
KR (1)	KR850007590A (da)
AT (1)	ATE46147T1 (da)
CA (1)	CA1241655A (da)
DE (2)	DE3414801A1 (da)
DK (1)	DK176085A (da)
ES (1)	ES8607235A1 (da)
IL (1)	IL74921A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3544692A1 (de) *	1985-12-18	1987-06-19	Bayer Ag	Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
DE3700307A1 (de) *	1987-01-08	1988-07-21	Bayer Ag	Tetrahydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
WO1990011074A1 (en) *	1989-03-22	1990-10-04	Pang Peter K T	Parathyroid hypertensive factor
US5350771A (en) *	1989-03-22	1994-09-27	Peter K. T. Pang	Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers
US5886012A (en) *	1989-03-22	1999-03-23	Peter K. T. Pang	Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers
US5514678A (en) *	1992-03-26	1996-05-07	E. I. Du Pont De Nemours And Company	Arthropodicidal 1,2,4-triazinyl amides
WO2003099790A1 (en) *	2002-05-29	2003-12-04	Council Of Scientific And Industrial Research	Process for the preparation of 1,4-dihydropyridines and novel 1,4-dihydropyridines useful as therapeutic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ201395A (en) *	1981-07-30	1987-02-20	Bayer Ag	Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
US4361572A (en) *	1981-12-21	1982-11-30	Chugai Seiyaku Kabushiki Kaisha	Tetrahydronicotinamide derivative, pharmaceutical compositions and use
DE3239273A1 (de) *	1982-10-23	1984-04-26	Bayer Ag, 5090 Leverkusen	Tetrahydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
EP0125803A3 (en) *	1983-04-27	1987-01-21	FISONS plc	Pharmaceutically active dihydropyridines

1984
- 1984-04-19 DE DE19843414801 patent/DE3414801A1/de not_active Withdrawn
1985
- 1985-04-08 US US06/720,668 patent/US4621093A/en not_active Expired - Fee Related
- 1985-04-09 EP EP85104256A patent/EP0158956B1/de not_active Expired
- 1985-04-09 DE DE8585104256T patent/DE3572808D1/de not_active Expired
- 1985-04-09 AT AT85104256T patent/ATE46147T1/de not_active IP Right Cessation
- 1985-04-15 JP JP60078632A patent/JPS60233057A/ja active Pending
- 1985-04-16 IL IL74921A patent/IL74921A/xx unknown
- 1985-04-17 CA CA000479328A patent/CA1241655A/en not_active Expired
- 1985-04-17 KR KR1019850002573A patent/KR850007590A/ko not_active Ceased
- 1985-04-18 ES ES542393A patent/ES8607235A1/es not_active Expired
- 1985-04-18 DK DK176085A patent/DK176085A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL74921A0 (en)	1985-08-30
KR850007590A (ko)	1985-12-07
DE3572808D1 (en)	1989-10-12
DE3414801A1 (de)	1985-10-24
ES542393A0 (es)	1986-06-01
ES8607235A1 (es)	1986-06-01
ATE46147T1 (de)	1989-09-15
IL74921A (en)	1988-03-31
US4621093A (en)	1986-11-04
EP0158956A2 (de)	1985-10-23
DK176085A (da)	1985-10-20
JPS60233057A (ja)	1985-11-19
EP0158956A3 (en)	1987-07-22
EP0158956B1 (de)	1989-09-06
CA1241655A (en)	1988-09-06

Legal Events

Date	Code	Title	Description
1992-04-06	ATS	Application withdrawn

Publication	Publication Date	Title
DK114783D0 (da)	1983-03-09	Hidtil ukendte forbindelser, fremgangsmader til deres fremstilling samt deres anvendelse som laegemidler
DK138283A (da)	1983-09-28	Spiro(4.(3+n))-2-aza-3-carboxylsyre-derivater, fremgangsmaade til fremstilling deraf samt midler indeholdende disse forbindelser og deres anvendelse
ES466366A1 (es)	1978-10-01	Un procedimiento para preparar derivados de metasulfonamido-benzamida.
DK176085D0 (da)	1985-04-18	4-(nitrophenyl)-tetrahydropyridiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler
MY101864A (en)	1992-01-31	Barbituric acid derivatives
ES2003086A6 (es)	1988-10-16	Procedimiento de obtencion de tienoquinolicinsulfonamidas
EP0097056A3 (en)	1984-07-04	Herbicidal n-substituted-3,4,5,6-tetrahydrophthalamic acid derivatives
DK96086A (da)	1986-09-05	8-thiotetrahydroquinolinderivater, deres fremstilling og anvendelse som laegemidler
FI863150A0 (fi)	1986-08-01	Nya tetraoxofoereningar.
FI872997A0 (fi)	1987-07-07	Amidderivat.
ES515640A0 (es)	1983-10-01	"un procedimiento para la preparacion de pirimid-2-onas".
FI823732L (fi)	1983-05-06	Nya 1-furyl-3,4-dihydroisokinoliner, laekemedel innehaollande dessa samt deras framstaellningsfoerfaranden och deras anvaendning
DK280883D0 (da)	1983-06-17	Organophosphat-derivater, fremgangsmade til fremstilling deraf samt deres anvendelse som midler til bekaempelse af skadelige organismer
NO905521D0 (no)	1990-12-20	2-formylbenzylfosfonsyre-derivater, deres fremstilling oganvendelse til behandling av sykdommer som er foraarsaket av virus.
DK0413278T3 (da)	1997-04-07	Anvendelse af xanthinderivater mod mavesår
DK27081A (da)	1981-07-23	Indan-4-yl-n-alkyl-carbaminsyreestere,fremgangsmaade til fremstilling heraf samt deres anvendelse som fungicider
DK144684A (da)	1984-09-19	Phosphonsyreestere, fremgangsmaader til fremstilling deraf samt deres anvendelse til bekaempelse af skadelige organismer
ATE53389T1 (de)	1990-06-15	Analoga von 3-((4-aroylphenoxy (bzw. phenylthio)>-cyclopentancarbonsaeure.
DK501083A (da)	1984-05-03	Semicarbazider, fremgangsmaade til deres fremstilling samt deres anvendelse