DK1765779T3 - Nye substituerede piperidiner som modulatorer for dopamin-neurotransmission - Google Patents
Nye substituerede piperidiner som modulatorer for dopamin-neurotransmissionInfo
- Publication number
- DK1765779T3 DK1765779T3 DK05750549.7T DK05750549T DK1765779T3 DK 1765779 T3 DK1765779 T3 DK 1765779T3 DK 05750549 T DK05750549 T DK 05750549T DK 1765779 T3 DK1765779 T3 DK 1765779T3
- Authority
- DK
- Denmark
- Prior art keywords
- occupies
- modulators
- substituted piperidines
- proviso
- trifluoromethyl
- Prior art date
Links
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 title 2
- 229960003638 dopamine Drugs 0.000 title 1
- 150000003053 piperidines Chemical class 0.000 title 1
- 230000005062 synaptic transmission Effects 0.000 title 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 4
- -1 OSO2CH3 Chemical group 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004206 2,2,2-trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 abstract 1
- 125000004200 2-methoxyethyl group Chemical group [H]C([H])([H])OC([H])([H])C([H])([H])* 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- KQKFQBTWXOGINC-UHFFFAOYSA-N 4-phenylpiperidin-4-ol Chemical class C=1C=CC=CC=1C1(O)CCNCC1 KQKFQBTWXOGINC-UHFFFAOYSA-N 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- UHCBBWUQDAVSMS-UHFFFAOYSA-N fluoroethane Chemical compound CCF UHCBBWUQDAVSMS-UHFFFAOYSA-N 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002827 triflate group Chemical group FC(S(=O)(=O)O*)(F)F 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000001889 triflyl group Chemical group FC(F)(F)S(*)(=O)=O 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/584—Recycling of catalysts
Landscapes
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57776704P | 2004-06-08 | 2004-06-08 | |
| SE0401465A SE0401465D0 (sv) | 2004-06-08 | 2004-06-08 | New substituted piperdines as modulators of dopamine neurotransmission |
| PCT/EP2005/006152 WO2005121092A1 (en) | 2004-06-08 | 2005-06-08 | New substituted piperidines as modulators of dopamine neurotransmission |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1765779T3 true DK1765779T3 (da) | 2010-04-06 |
Family
ID=39078673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05750549.7T DK1765779T3 (da) | 2004-06-08 | 2005-06-08 | Nye substituerede piperidiner som modulatorer for dopamin-neurotransmission |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP2008501748A (da) |
| AT (1) | ATE449071T1 (da) |
| DE (1) | DE602005017780D1 (da) |
| DK (1) | DK1765779T3 (da) |
| MX (1) | MXPA06013945A (da) |
| NZ (1) | NZ552410A (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201613859A (en) * | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3284457A (en) * | 1964-01-17 | 1966-11-08 | Degussa | 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts |
| FR1455825A (fr) * | 1965-02-18 | 1966-05-20 | Degussa | Procédé de préparation de phényl-tétrahydropyridines substituées |
| US4132710A (en) * | 1976-12-20 | 1979-01-02 | Ayerst, Mckenna And Harrison, Ltd. | [2]Benzopyrano[3,4-c]pyridines and process therefor |
| SE9904723D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
-
2005
- 2005-06-08 AT AT05750549T patent/ATE449071T1/de active
- 2005-06-08 JP JP2007526288A patent/JP2008501748A/ja active Pending
- 2005-06-08 DK DK05750549.7T patent/DK1765779T3/da active
- 2005-06-08 DE DE602005017780T patent/DE602005017780D1/de not_active Expired - Lifetime
- 2005-06-08 NZ NZ552410A patent/NZ552410A/en not_active IP Right Cessation
- 2005-06-08 MX MXPA06013945A patent/MXPA06013945A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ATE449071T1 (de) | 2009-12-15 |
| MXPA06013945A (es) | 2007-10-08 |
| NZ552410A (en) | 2010-04-30 |
| JP2008501748A (ja) | 2008-01-24 |
| DE602005017780D1 (de) | 2009-12-31 |
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