NZ552410A - New 4-phenyl-piperidin-4-ol derivatives as modulators of dopamine neurotransmission - Google Patents

New 4-phenyl-piperidin-4-ol derivatives as modulators of dopamine neurotransmission

Info

Publication number: NZ552410A
Authority: NZ; New Zealand
Prior art keywords: group; phenyl; propylpiperidin; disorders; chloro
Prior art date: 2004-06-08

Application number

NZ552410A

Other languages

English (en)

Inventor

Clas Sonesson

Lars Swanson

Nicholas Waters

Original Assignee

Nsab Af Neurosearch Sweden Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-08

Filing date

2005-06-08

Publication date

2010-04-30

2004-06-08 Priority claimed from SE0401465A external-priority patent/SE0401465D0/xx

2005-06-08 Application filed by Nsab Af Neurosearch Sweden Ab filed Critical Nsab Af Neurosearch Sweden Ab

2010-04-30 Publication of NZ552410A publication Critical patent/NZ552410A/en

Links

KQKFQBTWXOGINC-UHFFFAOYSA-N 4-phenylpiperidin-4-ol Chemical class C=1C=CC=CC=1C1(O)CCNCC1 KQKFQBTWXOGINC-UHFFFAOYSA-N 0.000 title abstract 2
VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 title description 48
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-1 OSO2CH3 Chemical group 0.000 claims abstract description 30
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims abstract description 28
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 27
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 16
210000003169 central nervous system Anatomy 0.000 claims abstract description 14
229910052739 hydrogen Inorganic materials 0.000 claims abstract description 14
150000003839 salts Chemical class 0.000 claims abstract description 14
125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims abstract description 11
229910052731 fluorine Inorganic materials 0.000 claims abstract description 9
229910052794 bromium Inorganic materials 0.000 claims abstract description 8
229910052740 iodine Inorganic materials 0.000 claims abstract description 8
125000004200 2-methoxyethyl group Chemical group [H]C([H])([H])OC([H])([H])C([H])([H])* 0.000 claims abstract description 6
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UHCBBWUQDAVSMS-UHFFFAOYSA-N fluoroethane Chemical compound CCF UHCBBWUQDAVSMS-UHFFFAOYSA-N 0.000 claims abstract description 5
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Classifications

- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/584—Recycling of catalysts

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Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NZ552410A 2004-06-08 2005-06-08 New 4-phenyl-piperidin-4-ol derivatives as modulators of dopamine neurotransmission NZ552410A (en)

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US57776704P	2004-06-08	2004-06-08
SE0401465A SE0401465D0 (sv)	2004-06-08	2004-06-08	New substituted piperdines as modulators of dopamine neurotransmission
PCT/EP2005/006152 WO2005121092A1 (en)	2004-06-08	2005-06-08	New substituted piperidines as modulators of dopamine neurotransmission

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AT (1)	ATE449071T1 (da)
DE (1)	DE602005017780D1 (da)
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MX (1)	MXPA06013945A (da)
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US3284457A (en) *	1964-01-17	1966-11-08	Degussa	1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
FR1455825A (fr) *	1965-02-18	1966-05-20	Degussa	Procédé de préparation de phényl-tétrahydropyridines substituées
US4132710A (en) *	1976-12-20	1979-01-02	Ayerst, Mckenna And Harrison, Ltd.	[2]Benzopyrano[3,4-c]pyridines and process therefor
SE9904723D0 (sv) *	1999-12-22	1999-12-22	Carlsson A Research Ab	New modulators of dopamine neurotransmission II

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- 2005-06-08 AT AT05750549T patent/ATE449071T1/de active
- 2005-06-08 JP JP2007526288A patent/JP2008501748A/ja active Pending
- 2005-06-08 DK DK05750549.7T patent/DK1765779T3/da active
- 2005-06-08 DE DE602005017780T patent/DE602005017780D1/de not_active Expired - Lifetime
- 2005-06-08 NZ NZ552410A patent/NZ552410A/en not_active IP Right Cessation
- 2005-06-08 MX MXPA06013945A patent/MXPA06013945A/es active IP Right Grant

Also Published As

Publication number	Publication date
ATE449071T1 (de)	2009-12-15
MXPA06013945A (es)	2007-10-08
DK1765779T3 (da)	2010-04-06
JP2008501748A (ja)	2008-01-24
DE602005017780D1 (de)	2009-12-31

Legal Events

Date	Code	Title
2010-08-27	PSEA	Patent sealed
2010-12-24	RENW	Renewal (renewal fees accepted)
2012-06-29	RENW	Renewal (renewal fees accepted)
2015-12-24	LAPS	Patent lapsed

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US8314126B2 (en)	2012-11-20	Disubstituted phenylpiperdines/piperazines as modulators of dopamine neurotransmission
US8501777B2 (en)	2013-08-06	3,5-disubstituted phenyl-piperidines as modulators of dopamine neurotransmission
NZ552410A (en)	2010-04-30	New 4-phenyl-piperidin-4-ol derivatives as modulators of dopamine neurotransmission
US7851629B2 (en)	2010-12-14	Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
RU2366654C2 (ru)	2009-09-10	Новые дизамещенные фенилпиперидины/пиперазины в качестве модуляторов допаминовой нейротрансмиссии
MX2008004603A (es)	2008-10-03	Fenil-piperidinas 3,5-disustituidas como moduladores de neurotransmision de dopamina
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HK1105153A (en)	2008-02-01	New disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission