DK1767526T3 - Arylamidinderivat, salt deraf og antifungalt middel, der indeholder disse - Google Patents

Arylamidinderivat, salt deraf og antifungalt middel, der indeholder disse

Info

Publication number
DK1767526T3
DK1767526T3 DK05765373.5T DK05765373T DK1767526T3 DK 1767526 T3 DK1767526 T3 DK 1767526T3 DK 05765373 T DK05765373 T DK 05765373T DK 1767526 T3 DK1767526 T3 DK 1767526T3
Authority
DK
Denmark
Prior art keywords
arylamide
ingredients
salts
antifungal agents
agents containing
Prior art date
Application number
DK05765373.5T
Other languages
English (en)
Inventor
Kazuya Hayashi
Kazuto Kunitani
Sayuri Uehara
Teiichi Morita
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of DK1767526T3 publication Critical patent/DK1767526T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
DK05765373.5T 2004-06-30 2005-06-28 Arylamidinderivat, salt deraf og antifungalt middel, der indeholder disse DK1767526T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004193386 2004-06-30
PCT/JP2005/011809 WO2006003881A1 (ja) 2004-06-30 2005-06-28 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤

Publications (1)

Publication Number Publication Date
DK1767526T3 true DK1767526T3 (da) 2012-11-12

Family

ID=35782688

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05765373.5T DK1767526T3 (da) 2004-06-30 2005-06-28 Arylamidinderivat, salt deraf og antifungalt middel, der indeholder disse

Country Status (20)

Country Link
US (1) US7700623B2 (da)
EP (1) EP1767526B1 (da)
JP (1) JP4885722B2 (da)
KR (1) KR101169694B1 (da)
CN (1) CN100567267C (da)
AU (1) AU2005258613B2 (da)
BR (1) BRPI0512661B8 (da)
CA (1) CA2572161C (da)
CY (1) CY1113266T1 (da)
DK (1) DK1767526T3 (da)
ES (1) ES2393924T3 (da)
IL (1) IL180192A (da)
NO (1) NO339158B1 (da)
NZ (1) NZ552184A (da)
PL (1) PL1767526T3 (da)
PT (1) PT1767526E (da)
RU (1) RU2359959C2 (da)
SI (1) SI1767526T1 (da)
WO (1) WO2006003881A1 (da)
ZA (1) ZA200700806B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1867332T1 (sl) 2005-04-07 2011-11-30 Toyama Chemical Co Ltd Farmacevtska sestava in postopek z rabo v kombinaciji s protiglivičnim sredstvom
AU2006264649A1 (en) * 2005-06-30 2007-01-11 Prosidion Limited GPCR agonists
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
ZA200805604B (en) * 2005-12-29 2009-12-30 Toyama Chemical Co Ltd Novel arylamidine derivative, salt thereof and antifungal agent containing those
JP5132569B2 (ja) 2006-10-06 2013-01-30 富山化学工業株式会社 フェニルアミジン誘導体を含有する医薬組成物および抗真菌剤を組み合わせて使用する方法
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
TWI395735B (zh) * 2007-07-04 2013-05-11 Toyama Chemical Co Ltd 4-{3-〔4-(3-{4-〔胺基(丁氧基羰基亞胺基)甲基〕苯氧基}丙基)-1-哌啶基〕丙氧基}-n’-(丁氧基羰基)苄脒之新穎結晶
DE102008007440A1 (de) * 2008-02-01 2009-08-13 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg Aminosäurederivate als Arzneistoffe
DE102008007381A1 (de) * 2008-02-01 2009-08-13 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg Amidine und Guanidine und deren Derivate zur Behandlung von Krankheiten
AU2014200451B2 (en) * 2008-02-01 2016-03-03 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg Use of amidoxime carboxylic acid esters and n-hydroxyguanidine carboxylic acid esters for producing prodrugs
US9662308B2 (en) 2008-02-01 2017-05-30 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg Orally bioavailable pentamidine prodrugs for the treatment of diseases
WO2011104540A1 (en) * 2010-02-24 2011-09-01 Generics [Uk] Limited One step process for the preparation of capecitabine
WO2012043701A1 (ja) 2010-09-30 2012-04-05 富山化学工業株式会社 経皮吸収製剤
WO2012060448A1 (ja) 2010-11-05 2012-05-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗真菌剤としての併用医薬組成物
MX2022005326A (es) * 2019-11-04 2022-07-19 Appili Therapeutics Inc Composición y metodo para tratar infección por candida auris.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE268751T1 (de) * 1997-11-20 2004-06-15 Teijin Ltd Biphenylamidin-derivate
DK1481966T3 (da) * 2002-03-06 2011-10-24 Toyama Chemical Co Ltd Nyt arylamidinderivat eller salt deraf

Also Published As

Publication number Publication date
CN100567267C (zh) 2009-12-09
IL180192A (en) 2011-01-31
ES2393924T3 (es) 2013-01-02
US7700623B2 (en) 2010-04-20
BRPI0512661A (pt) 2008-04-01
BRPI0512661B1 (pt) 2020-10-27
RU2359959C2 (ru) 2009-06-27
RU2007103176A (ru) 2008-08-10
CA2572161C (en) 2012-10-02
AU2005258613A1 (en) 2006-01-12
SI1767526T1 (sl) 2013-02-28
CY1113266T1 (el) 2016-04-13
NZ552184A (en) 2009-11-27
AU2005258613B2 (en) 2011-03-17
JPWO2006003881A1 (ja) 2008-04-17
NO339158B1 (no) 2016-11-14
KR20070030305A (ko) 2007-03-15
CN1976901A (zh) 2007-06-06
EP1767526A1 (en) 2007-03-28
JP4885722B2 (ja) 2012-02-29
US20080319016A1 (en) 2008-12-25
PL1767526T3 (pl) 2013-03-29
ZA200700806B (en) 2008-12-31
BRPI0512661B8 (pt) 2021-05-25
CA2572161A1 (en) 2006-01-12
PT1767526E (pt) 2012-12-10
NO20070455L (no) 2007-01-24
KR101169694B1 (ko) 2012-07-31
IL180192A0 (en) 2007-06-03
EP1767526B1 (en) 2012-10-24
EP1767526A4 (en) 2009-05-06
WO2006003881A1 (ja) 2006-01-12

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