DK178180A - Fremgangsmaade til frmstilling af 3-(hydroxyethyl) azetidiononer - Google Patents

Fremgangsmaade til frmstilling af 3-(hydroxyethyl) azetidiononer

Info

Publication number: DK178180A
Authority: DK; Denmark
Prior art keywords: hydroxyethyl; azetidionones; preparing; thienamycin; azetidinones
Prior art date: 1979-04-27

Application number

DK178180A

Other languages

Danish (da)

English (en)

Inventor

F A Bouffard

B G Christensen

R W Ratcliffe

T N Salzmann

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-04-27

Filing date

1980-04-25

Publication date

1980-10-28

1980-04-25 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1980-10-28 Publication of DK178180A publication Critical patent/DK178180A/da

Links

238000000034 method Methods 0.000 title abstract 2
125000000954 2-hydroxyethyl group Chemical class [H]C([*])([H])C([H])([H])O[H] 0.000 title 1
UMHGAVAUBIVOAL-UHFFFAOYSA-N 3-(1-hydroxyethyl)azetidin-2-one Chemical class CC(O)C1CNC1=O UMHGAVAUBIVOAL-UHFFFAOYSA-N 0.000 abstract 1
WKDDRNSBRWANNC-ATRFCDNQSA-N Thienamycin Chemical compound C1C(SCCN)=C(C(O)=O)N2C(=O)[C@H]([C@H](O)C)[C@H]21 WKDDRNSBRWANNC-ATRFCDNQSA-N 0.000 abstract 1
WKDDRNSBRWANNC-UHFFFAOYSA-N Thienamycin Natural products C1C(SCCN)=C(C(O)=O)N2C(=O)C(C(O)C)C21 WKDDRNSBRWANNC-UHFFFAOYSA-N 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK178180A 1979-04-27 1980-04-25 Fremgangsmaade til frmstilling af 3-(hydroxyethyl) azetidiononer DK178180A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3405379A	1979-04-27	1979-04-27

Publications (1)

Publication Number	Publication Date
DK178180A true DK178180A (da)	1980-10-28

Family

ID=21874008

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK178180A DK178180A (da)	1979-04-27	1980-04-25	Fremgangsmaade til frmstilling af 3-(hydroxyethyl) azetidiononer

Country Status (5)

Country	Link
EP (1)	EP0018594B1 (de)
JP (1)	JPS56108785A (de)
AT (1)	ATE15039T1 (de)
DE (1)	DE3071008D1 (de)
DK (1)	DK178180A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4446146A (en) *	1978-07-26	1984-05-01	Beecham Group Limited	β-Lactam containing compounds, their preparation and use
PT71552B (en) *	1979-07-23	1981-12-14	Merck & Co Inc	Process for preparation of thienamycin and intermediates
JPS57167964A (en) *	1981-04-09	1982-10-16	Toyama Chem Co Ltd	Preparation of (4r)-3-substituted-4-(substituted or unsubstituted carboxymethyl)-2-azetidinone derivative
DE3269313D1 (en) *	1981-05-14	1986-04-03	Beecham Group Plc	Process for the preparation of an enantiomer of a beta-lactam derivative
JPS58103358A (ja) *	1981-10-23	1983-06-20	メルク・エンド・カムパニ−・インコ−ポレ−テツド	抗生物質中間体の製造方法
HU184494B (en) *	1981-12-30	1984-08-28	Richter Gedeon Vegyeszet	Process for producing new azetidinone-caraoxylic acids
HU185081B (en) *	1981-12-30	1984-11-28	Richter Gedeon Vegyeszet	Process for preparing azetidinone-acetic acid derivatives
DE3581481D1 (de) *	1984-10-31	1991-02-28	Sumitomo Pharma	Beta-lactame und ihre herstellung.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK488077A (da) *	1976-11-19	1978-05-20	Merck & Co Inc	Fremgangsmaade til fremstilling af 3-(2-aminoethylthio)-6(-1-hydroxyethyl)-7-oxo-1-azabicyclo (3.2.0) hept-2-en-2-carboxylsyre
GB1593524A (en) *	1976-11-19	1981-07-15	Merck & Co Inc	1-carba-2-penem-3-carboxylic acids
US4174316A (en) *	1978-08-14	1979-11-13	Merck & Co., Inc.	4-Iodomethylazetidin-2-one
DK165280A (da) *	1979-04-19	1980-10-20	Merck & Co Inc	Fremgangsmaade til fremstilling af 2- og 6-substituerede 1-carbadethiapen-2-em-3-carboxylsyrer og mellemprodukter til brug ved udoevelse af fremgangsmaaden
PT71552B (en) *	1979-07-23	1981-12-14	Merck & Co Inc	Process for preparation of thienamycin and intermediates
US4262010A (en) *	1979-12-03	1981-04-14	Merck & Co., Inc.	6-(1-Hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids
GR72296B (de) *	1979-12-03	1983-10-18	Merck & Co Inc
IE52147B1 (en) *	1980-03-27	1987-07-08	Merck & Co Inc	4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
DE3169321D1 (en) *	1980-03-27	1985-04-25	Merck & Co Inc	Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals

1980
- 1980-04-24 DE DE8080102202T patent/DE3071008D1/de not_active Expired
- 1980-04-24 AT AT80102202T patent/ATE15039T1/de not_active IP Right Cessation
- 1980-04-24 EP EP80102202A patent/EP0018594B1/de not_active Expired
- 1980-04-25 DK DK178180A patent/DK178180A/da not_active Application Discontinuation
- 1980-04-28 JP JP5554680A patent/JPS56108785A/ja active Pending

Also Published As

Publication number	Publication date
EP0018594A2 (de)	1980-11-12
EP0018594A3 (en)	1981-01-07
ATE15039T1 (de)	1985-09-15
EP0018594B1 (de)	1985-08-21
DE3071008D1 (en)	1985-09-26
JPS56108785A (en)	1981-08-28

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Legal Events

Date	Code	Title	Description
1986-01-01	AHB	Application shelved due to non-payment