DK178488A - Amino-5,6,7,8-tetrahydronaphtho(2,3-b)furanderivater, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem - Google Patents

Amino-5,6,7,8-tetrahydronaphtho(2,3-b)furanderivater, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem

Info

Publication number: DK178488A
Authority: DK; Denmark
Prior art keywords: radical; carbon atoms; linear; amino; denotes
Prior art date: 1987-04-01

Application number

DK178488A

Other languages

English (en)

Other versions

DK166496B1 (da

DK178488D0 (da

Inventor

Jean-Louis Peglion

Jean-Claude Poignant

Joel Vian

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-01

Filing date

1988-03-30

Publication date

1988-10-02

1988-03-30 Application filed by Adir filed Critical Adir

1988-03-30 Publication of DK178488D0 publication Critical patent/DK178488D0/da

1988-10-02 Publication of DK178488A publication Critical patent/DK178488A/da

1993-06-01 Application granted granted Critical

1993-06-01 Publication of DK166496B1 publication Critical patent/DK166496B1/da

Links

239000003814 drug Substances 0.000 title 1
238000000034 method Methods 0.000 title 1
-1 alkyl radical Chemical class 0.000 abstract 11
125000004432 carbon atom Chemical group C* 0.000 abstract 7
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
230000001430 anti-depressive effect Effects 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
229940005513 antidepressants Drugs 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
230000003291 dopaminomimetic effect Effects 0.000 abstract 1
ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK178488A 1987-04-01 1988-03-30 Amino-5,6,7,8-tetrahydronaphthooe2,3-baafuranderivater og fremgangsmaade til deres fremstilling DK166496B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8704551A FR2613365B1 (fr)	1987-04-01	1987-04-01	Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR8704551		1987-04-01

Publications (3)

Publication Number	Publication Date
DK178488D0 DK178488D0 (da)	1988-03-30
DK178488A true DK178488A (da)	1988-10-02
DK166496B1 DK166496B1 (da)	1993-06-01

Family

ID=9349665

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK178488A DK166496B1 (da)	1987-04-01	1988-03-30	Amino-5,6,7,8-tetrahydronaphthooe2,3-baafuranderivater og fremgangsmaade til deres fremstilling

Country Status (16)

Country	Link
US (2)	US4863951A (da)
EP (1)	EP0286516B1 (da)
JP (1)	JPH068286B2 (da)
AT (1)	ATE73790T1 (da)
AU (1)	AU602565B2 (da)
CA (1)	CA1314050C (da)
DE (1)	DE3869173D1 (da)
DK (1)	DK166496B1 (da)
ES (1)	ES2006623A6 (da)
FR (1)	FR2613365B1 (da)
GR (1)	GR1000155B (da)
IE (1)	IE61007B1 (da)
NZ (1)	NZ224099A (da)
OA (1)	OA08825A (da)
PT (1)	PT87147B (da)
ZA (1)	ZA882282B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2613364B1 (fr) *	1987-04-01	1989-06-09	Adir	Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US5071875A (en) *	1989-09-25	1991-12-10	Northwestern University	Substituted 2-amidotetralins as melatonin agonists and antagonists
FR2689509B1 (fr) *	1992-04-01	1994-06-03	Adir	Nouveaux derives spiraniques du 3-amino chromane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
ATE195935T1 (de) *	1993-03-25	2000-09-15	Upjohn Co	Formyl- oder cyano- substituierte indolderivate mit dopaminergischer wirkung
US5674891A (en) *	1994-07-27	1997-10-07	The Procter & Gamble Company	Dihydrobenzothiophene compounds useful as anti-inflammatory agents
JPH10506615A (ja) *	1994-07-27	1998-06-30	ザ、プロクター、エンド、ギャンブル、カンパニー	抗炎症剤として有用なジヒドロベンゾフラン及び関連化合物
FR2725985B1 (fr) *	1994-10-21	1996-11-15	Adir	Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5998461A (en) *	1994-10-21	1999-12-07	Adir Et Compagnie	Tricyclic amide compounds
US6071946A (en) *	1994-10-21	2000-06-06	Adir Et Compagnie	Tricyclic urea compounds
FR2739379B1 (fr) *	1995-09-29	1997-10-24	Adir	Nouveaux composes amines de 5,6,7,8-tetrahydronaphto(2,3-b) furane et d'indano(5,6-b)furane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2739855B1 (fr) *	1995-10-13	1997-11-14	Adir	Nouvelles amines heterocycliques tertiaires, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5672620A (en) *	1996-02-01	1997-09-30	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) *	1996-02-01	1997-11-04	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
DE10041478A1 (de)	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung
DE10334187A1 (de) *	2003-07-26	2005-03-03	Schwarz Pharma Ag	Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) *	2003-07-26	2007-07-05	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung von Depressionen
EP2123265B1 (en) *	2008-05-23	2012-05-23	NOVAERA S.r.l.	Endipalene formulations in the treatment of psoriasis
CN102264733B (zh)	2008-10-10	2014-07-30	中国人民解放军军事医学科学院毒物药物研究所	新型多巴胺d3受体配体，其制备方法及其医药用途
US9227944B2 (en)	2008-10-10	2016-01-05	Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China	Dopamine D3 receptor ligands and preparation and medical uses of the same
CN116209657A (zh) *	2020-08-06	2023-06-02	泰科根公司	用于精神障碍或增强的2-氨基茚满化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1084440A (en) *	1963-12-31	1967-09-20	Upjohn Co	Improvements in or relating to (2-aminocycloalkyl) hydroquinones and the manufacturethereof
US4470990A (en) *	1983-03-14	1984-09-11	Ayerst, Mckenna & Harrison Inc.	6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants
FR2613364B1 (fr) *	1987-04-01	1989-06-09	Adir	Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

1987
- 1987-04-01 FR FR8704551A patent/FR2613365B1/fr not_active Expired
1988
- 1988-03-22 CA CA000562140A patent/CA1314050C/fr not_active Expired - Fee Related
- 1988-03-25 US US07/173,285 patent/US4863951A/en not_active Expired - Fee Related
- 1988-03-30 ES ES8801011A patent/ES2006623A6/es not_active Expired
- 1988-03-30 DK DK178488A patent/DK166496B1/da not_active IP Right Cessation
- 1988-03-30 ZA ZA882282A patent/ZA882282B/xx unknown
- 1988-03-31 PT PT87147A patent/PT87147B/pt not_active IP Right Cessation
- 1988-03-31 JP JP63080188A patent/JPH068286B2/ja not_active Expired - Lifetime
- 1988-03-31 EP EP88400780A patent/EP0286516B1/fr not_active Expired - Lifetime
- 1988-03-31 AT AT88400780T patent/ATE73790T1/de active
- 1988-03-31 NZ NZ224099A patent/NZ224099A/xx unknown
- 1988-03-31 IE IE97188A patent/IE61007B1/en not_active IP Right Cessation
- 1988-03-31 OA OA59315A patent/OA08825A/xx unknown
- 1988-03-31 GR GR880100208A patent/GR1000155B/el unknown
- 1988-03-31 DE DE8888400780T patent/DE3869173D1/de not_active Expired - Lifetime
- 1988-03-31 AU AU14049/88A patent/AU602565B2/en not_active Ceased
1989
- 1989-01-27 US US07/303,545 patent/US4885373A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK166496B1 (da)	1993-06-01
PT87147A (pt)	1988-04-01
IE880971L (en)	1988-10-01
DE3869173D1 (de)	1992-04-23
AU1404988A (en)	1988-10-06
PT87147B (pt)	1992-07-31
EP0286516A1 (fr)	1988-10-12
GR1000155B (el)	1991-09-27
ATE73790T1 (de)	1992-04-15
IE61007B1 (en)	1994-09-07
US4863951A (en)	1989-09-05
US4885373A (en)	1989-12-05
ZA882282B (en)	1988-09-22
EP0286516B1 (fr)	1992-03-18
FR2613365B1 (fr)	1989-07-28
JPS63258870A (ja)	1988-10-26
CA1314050C (fr)	1993-03-02
AU602565B2 (en)	1990-10-18
DK178488D0 (da)	1988-03-30
NZ224099A (en)	1990-05-28
FR2613365A1 (fr)	1988-10-07
GR880100208A (en)	1989-01-31
JPH068286B2 (ja)	1994-02-02
ES2006623A6 (es)	1989-05-01
OA08825A (fr)	1989-03-31

Legal Events

Date	Code	Title	Description
1993-06-01	B1	Patent granted (law 1993)
1999-03-08	PBP	Patent lapsed

Publication	Publication Date	Title
DK178488A (da)	1988-10-02	Amino-5,6,7,8-tetrahydronaphtho(2,3-b)furanderivater, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem
DK584886A (da)	1987-06-07	Vanduoploeselige, mono- og disubstituerede derivater af rapamycin og farmaceutisk acceptable salte deraf
YU108791A (sh)	1994-01-20	Pirazolopirimidinon antianginalna jedinjenja
CY1108019T1 (el)	2013-09-04	Ενωσεις πυριμιδινης
CO4700455A1 (es)	1998-12-29	Derivados tetraciclicos y proceso para su preparacion
FI882813A0 (fi)	1988-06-13	Pyrazolopyridinfoerening och foerfarande foer dess framstaellning.
DK0467248T3 (da)	1999-07-05	Pyrazolopyridinforbindelse og fremgangsmåder til fremstilling heraf
DK0657458T3 (da)	2001-10-29	Inhibitorer af proteinkinase-C
ATE289602T1 (de)	2005-03-15	Quinolin-2-on-derivate verwendbar als antikrebsmittel
NZ235658A (en)	1992-12-23	Anthraquinone derivatives containing at least one n'-disubstituted n'-oxide alkylamino substituent; preparatory processes and intermediates
MX9206939A (es)	1993-06-01	Derivados de piperazina, procedimiento para su preparacion y composicion farmaceutica que los comprende
FI890689A0 (fi)	1989-02-14	3-alkenyl-1-azabicyklo-/3.2.0/ -hept-2-en-2-karboxylsyrafoereningar.
ES2032335T3 (es)	1993-02-01	Nuevos derivados flavonoides 2-piperazinil-2-oxo-etilen sustituidos, sus procedimientos de preparacion y las composiciones farmaceuticas que los contienen.
GR3005961T3 (da)	1993-06-07
DK165691C (da)	1993-06-07	Tricykliske aminer afledt af 2,3,5,6,7,8-hexahydronaphtho(2,3-b)furan, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
DE69405214D1 (de)	1997-10-02	3'-azaridino-anthracyclin-derivate
NO983444L (no)	1998-07-24	Benzo(c)kinolizin derivater, deres fremstilling og anvendelse som 5<alfa>-reduktaseinhibitorer
DK104388A (da)	1988-08-28	Hidtil ukendte 2-(2,3-dihydro-2-oxo-3-benzofuranyl)-eddikesyrederivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
DE69014337D1 (de)	1995-01-12	Verwendung von 5-Alkylpyridazin-Derivaten als Medikamente zur Beeinflussung des cholinergen Systems.
ES2045514T3 (es)	1994-01-16	Utilizacion de derivados del cromano para el tratamiento de los estados depresivos.
DK163922C (da)	1992-09-21	2,3-dihydro-3-phenyl-2-benzofuranonderivater, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem
DK214190A (da)	1990-09-06	5-aminosulfonylmethyl-indolderivater og farmaceutiske praeparater med indhold deraf