ATE114469T1 - Verwendung von 5-alkylpyridazin-derivaten als medikamente zur beeinflussung des cholinergen systems. - Google Patents

Verwendung von 5-alkylpyridazin-derivaten als medikamente zur beeinflussung des cholinergen systems.

Info

Publication number: ATE114469T1
Authority: AT; Austria
Prior art keywords: alkylpyridazine; derivatives; cholinergenic; medications; influence
Prior art date: 1989-02-07

Application number

AT90400335T

Other languages

English (en)

Inventor

Robert Boigegrain

Camille Georges Wermuth

Paul Worms

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-07

Filing date

1990-02-07

Publication date

1994-12-15

1990-02-07 Application filed by Sanofi Sa filed Critical Sanofi Sa

1994-12-15 Application granted granted Critical

1994-12-15 Publication of ATE114469T1 publication Critical patent/ATE114469T1/de

Links

229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
230000001713 cholinergic effect Effects 0.000 abstract 1
230000001054 cortical effect Effects 0.000 abstract 1
230000007812 deficiency Effects 0.000 abstract 1
230000003412 degenerative effect Effects 0.000 abstract 1
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
230000001575 pathological effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000009758 senescence Effects 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT90400335T 1989-02-07 1990-02-07 Verwendung von 5-alkylpyridazin-derivaten als medikamente zur beeinflussung des cholinergen systems. ATE114469T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8901546A FR2642648B1 (fr)	1989-02-07	1989-02-07	Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique

Publications (1)

Publication Number	Publication Date
ATE114469T1 true ATE114469T1 (de)	1994-12-15

Family

ID=9378542

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90400335T ATE114469T1 (de)	1989-02-07	1990-02-07	Verwendung von 5-alkylpyridazin-derivaten als medikamente zur beeinflussung des cholinergen systems.

Country Status (8)

Country	Link
US (1)	US5081119A (de)
EP (1)	EP0382635B1 (de)
JP (1)	JPH02240070A (de)
AT (1)	ATE114469T1 (de)
CA (1)	CA2009502A1 (de)
DE (1)	DE69014337D1 (de)
FR (1)	FR2642648B1 (de)
PT (1)	PT93061B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5631255A (en) *	1989-02-07	1997-05-20	Sanofi	Pyridazine derivatives
FR2663326B2 (fr) *	1989-11-17	1992-10-16	Sanofi Sa	Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
US5461053A (en) *	1989-02-07	1995-10-24	Sanofi	Pyridazine derivatives
FR2676444B1 (fr) *	1991-05-16	1995-03-10	Sanofi Elf	Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US6699866B2 (en)	2001-04-17	2004-03-02	Sepracor Inc.	Thiazole and other heterocyclic ligands for mammalian dopamine, muscarinic and serotonin receptors and transporters, and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1345880A (en) *	1971-06-18	1974-02-06	Cepbepe	Pyridazine derivatives
FR2510998B1 (fr) *	1981-08-07	1986-01-10	Sanofi Sa	Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) *	1981-08-10	1983-02-11	Sanofi Sa	Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
PT93060B (pt) *	1989-02-07	1995-12-29	Sanofi Sa	Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem

1989
- 1989-02-07 FR FR8901546A patent/FR2642648B1/fr not_active Expired - Fee Related
1990
- 1990-02-05 PT PT93061A patent/PT93061B/pt not_active IP Right Cessation
- 1990-02-07 AT AT90400335T patent/ATE114469T1/de not_active IP Right Cessation
- 1990-02-07 CA CA002009502A patent/CA2009502A1/en not_active Abandoned
- 1990-02-07 US US07/475,490 patent/US5081119A/en not_active Expired - Fee Related
- 1990-02-07 DE DE69014337T patent/DE69014337D1/de not_active Expired - Lifetime
- 1990-02-07 EP EP90400335A patent/EP0382635B1/de not_active Expired - Lifetime
- 1990-02-07 JP JP2028148A patent/JPH02240070A/ja active Pending

Also Published As

Publication number	Publication date
PT93061A (pt)	1990-08-31
EP0382635A3 (de)	1992-01-08
JPH02240070A (ja)	1990-09-25
DE69014337D1 (de)	1995-01-12
CA2009502A1 (en)	1990-08-07
EP0382635B1 (de)	1994-11-30
FR2642648A1 (fr)	1990-08-10
US5081119A (en)	1992-01-14
FR2642648B1 (fr)	1991-06-21
PT93061B (pt)	1995-12-29
EP0382635A2 (de)	1990-08-16

Similar Documents

Publication	Publication Date	Title
DK0513543T3 (da)	1996-02-26	Amidinophenylalaninderivater, fremgangsmåde til deres fremstilling, deres anvendelse og antikoagulationsmidler med indehold deraf
DK0657458T3 (da)	2001-10-29	Inhibitorer af proteinkinase-C
ATE195117T1 (de)	2000-08-15	1-amdinophenyl-pyrrolidone/piperidinone als blutblättchen-aggregations inhibitoren
BR9911013A (pt)	2001-02-06	Derivados de pirazol como inibidores da p-38 map quinase
IL97025A0 (en)	1992-03-29	17beta-substituted-4-aza-5alpha-androstan-3-one derivatives,their preparation and pharmaceutical compositions containing them
SE9203825L (sv)	1993-07-05	Dubbelt verkande inhibitorer foer no-syntas och cyklooxygenas, foerfarande foer framstaellning daerav och terapeutiska kompositioner innehaallande desamma
BR0014225A (pt)	2002-05-21	Derivados de pirazol
TR199701647A2 (xx)	1998-07-21	�kame edilmi� purin t�revleri,bunlar�n imalat usul�
DK178488A (da)	1988-10-02	Amino-5,6,7,8-tetrahydronaphtho(2,3-b)furanderivater, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem
MX9202544A (es)	1992-11-01	Compuestos de diaminoftalimidas substituidas y analogas, procedimiento para su preparacion y preparados farmaceuticos que los contienen.
ES2000481A6 (es)	1988-03-01	Procecimiento de preparacion de nuevos derivados del dihidro-2,3 benzofurano
ES2110115T3 (es)	1998-02-01	Inhibidores de la agregacion de plaquetas.
DE69014337D1 (de)	1995-01-12	Verwendung von 5-Alkylpyridazin-Derivaten als Medikamente zur Beeinflussung des cholinergen Systems.
BR9916046A (pt)	2001-10-02	Composto, composição farmacêutica, e, processos para inibir a replicação de um vìrus herpes e para tratamento de um paciente que sofra de uma infecção do vìrus herpes
NO983444D0 (no)	1998-07-24	Benzo(c)kinolizin derivater, deres fremstilling og anvendelse som 5<alfa>-reduktaseinhibitorer
DE69330601D1 (de)	2001-09-20	Serotoninergische ergolin derivate
DK601683A (da)	1984-06-29	Dialkylaminoalkoxybenzylalkoholderivater
HUP0001773A2 (hu)	2000-11-28	Szubsztituált tetrahidropiridinszármazékok, eljárás előállításukra, továbbá a vegyületeket tartalmazó gyógyászati készítmények
DK159769C (da)	1991-04-22	Resorcinderivater og analogifremgangsmaade til fremstilling heraf, farmaceutiske praeparater indeholdende disse, samt fremgangsmaade til fremstilling af disse farmaceutiske praeparater
BR0016115A (pt)	2002-08-20	Derivados peptìdicos de acriloìla, processo para sua preparação e seu uso como agentes inibidores de tumor
DK0410278T3 (da)	1994-05-24	Reninhæmmende aminooligohydroxyderivater
AP2003002831A0 (en)	2003-09-30	Derivatives of etoposide and analogs, and pharmaceutical compositions containing them
DK104388D0 (da)	1988-02-26	Hidtil ukendte 2-(2,3-dihydro-2-oxo-3-benzofuranyl)-eddikesyrederivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
PT92377A (pt)	1990-05-31	Processo para a obtencao de composicoes farmaceuticas para o tratamento de estados depressivos, contendo derivados de cromano
DK0586405T3 (da)	1997-12-01	Hidtil ukendte 2-H-benzo(b)pyranderivater substitueret i 4-stillingen med aryl eller N-heteroaryl, fremgangsmåder til fremstilling deraf og præparater indeholdende forbindelserne

Legal Events

Date	Code	Title	Description
1995-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties