DK181790A - Fermenteringsmedier og fremgangsmaader til regulering af norleucinindholdet i polypeptider - Google Patents

Fermenteringsmedier og fremgangsmaader til regulering af norleucinindholdet i polypeptider Download PDF

Info

Publication number: DK181790A
Authority: DK; Denmark
Prior art keywords: procedures; polypeptides; norleucin; regulating; content
Prior art date: 1988-02-17

Application number

DK181790A

Other languages

Danish (da)

English (en)

Other versions

DK181790D0 (da

Inventor

David P Brunner

Gary C Harbour

Richard J Kirschner

James F Pinner

Robert L Garlick

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-17

Filing date

1990-07-30

Publication date

1990-07-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22563048&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK181790(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-07-30 Application filed by Upjohn Co filed Critical Upjohn Co

1990-07-30 Publication of DK181790D0 publication Critical patent/DK181790D0/da

1990-07-30 Publication of DK181790A publication Critical patent/DK181790A/da

Links

238000000034 method Methods 0.000 title abstract 5
229920001184 polypeptide Polymers 0.000 title abstract 3
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
230000001105 regulatory effect Effects 0.000 title 1
238000000855 fermentation Methods 0.000 abstract 4
230000004151 fermentation Effects 0.000 abstract 4
LRQKBLKVPFOOQJ-YFKPBYRVSA-N L-norleucine Chemical compound CCCC[C@H]([NH3+])C([O-])=O LRQKBLKVPFOOQJ-YFKPBYRVSA-N 0.000 abstract 3
244000005700 microbiome Species 0.000 abstract 3
241000588724 Escherichia coli Species 0.000 abstract 1
108010006025 bovine growth hormone Proteins 0.000 abstract 1
238000010348 incorporation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Mycology (AREA)
Toxicology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK181790A 1988-02-17 1990-07-30 Fermenteringsmedier og fremgangsmaader til regulering af norleucinindholdet i polypeptider DK181790A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US15727588A	1988-02-17	1988-02-17
PCT/US1989/000425 WO1989007651A2 (en)	1988-02-17	1989-02-07	Methods for controlling norleucine content in polypeptides

Publications (2)

Publication Number	Publication Date
DK181790D0 DK181790D0 (da)	1990-07-30
DK181790A true DK181790A (da)	1990-07-30

Family

ID=22563048

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK181790A DK181790A (da)	1988-02-17	1990-07-30	Fermenteringsmedier og fremgangsmaader til regulering af norleucinindholdet i polypeptider

Country Status (7)

Country	Link
EP (2)	EP0737752A3 (de)
JP (1)	JP2879063B2 (de)
AT (1)	ATE152176T1 (de)
AU (1)	AU3058489A (de)
DE (1)	DE68927997T2 (de)
DK (1)	DK181790A (de)
WO (1)	WO1989007651A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU783954B2 (en)	2000-05-10	2006-01-05	Asubio Pharma Co., Ltd.	Method of inhibiting the formation of by-product in the production of genetically modified polypeptide
KR101234439B1 (ko)	2003-09-25	2013-02-18	몬산토 테크놀로지 엘엘씨	단백질 내로의 비―표준 아미노산의 도입 방지
RU2315807C2 (ru) *	2004-09-10	2008-01-27	Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ)	СПОСОБ ПОЛУЧЕНИЯ НОРЛЕЙЦИНА И НОРВАЛИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ РОДА Escherichia, В КОТОРОЙ ВСЕ СИНТАЗЫ АЦЕТОГИДРОКСИКИСЛОТ ИНАКТИВИРОВАНЫ
CN104662161A (zh) *	2012-09-19	2015-05-27	弗·哈夫曼-拉罗切有限公司	用于防止正亮氨酸错误地掺入蛋白质中的方法和组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4443545A (en) *	1980-08-25	1984-04-17	Massachusetts Institute Of Technology	Process for producing heparinase
US5037806A (en) *	1985-02-22	1991-08-06	Monsanto Company	Biologically active method using somatotropins
US4762784A (en) *	1985-07-15	1988-08-09	International Minerals & Chemical Corp.	Fermemtation process for the high level production of bovine growth hormone

1989
- 1989-02-07 EP EP96104679A patent/EP0737752A3/de not_active Ceased
- 1989-02-07 JP JP1502300A patent/JP2879063B2/ja not_active Expired - Lifetime
- 1989-02-07 WO PCT/US1989/000425 patent/WO1989007651A2/en not_active Ceased
- 1989-02-07 DE DE68927997T patent/DE68927997T2/de not_active Revoked
- 1989-02-07 AU AU30584/89A patent/AU3058489A/en not_active Abandoned
- 1989-02-07 AT AT89902468T patent/ATE152176T1/de active
- 1989-02-07 EP EP89902468A patent/EP0401254B1/de not_active Revoked
1990
- 1990-07-30 DK DK181790A patent/DK181790A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU3058489A (en)	1989-09-06
DE68927997D1 (de)	1997-05-28
WO1989007651A2 (en)	1989-08-24
JPH03502758A (ja)	1991-06-27
EP0401254A1 (de)	1990-12-12
DK181790D0 (da)	1990-07-30
WO1989007651A3 (en)	1989-11-02
ATE152176T1 (de)	1997-05-15
DE68927997T2 (de)	1997-09-11
EP0737752A2 (de)	1996-10-16
JP2879063B2 (ja)	1999-04-05
EP0401254B1 (de)	1997-04-23
EP0737752A3 (de)	1996-10-23

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Legal Events

Date	Code	Title	Description
2003-09-22	AHB	Application shelved due to non-payment