DK182990D0 - T-celleepitoper og oligopeptider, deres anvendelse i immunogene konjugater og immunokonjugater samt vacciner indeholdende disse konjugater - Google Patents

T-celleepitoper og oligopeptider, deres anvendelse i immunogene konjugater og immunokonjugater samt vacciner indeholdende disse konjugater

Info

Publication number
DK182990D0
DK182990D0 DK182990A DK182990A DK182990D0 DK 182990 D0 DK182990 D0 DK 182990D0 DK 182990 A DK182990 A DK 182990A DK 182990 A DK182990 A DK 182990A DK 182990 D0 DK182990 D0 DK 182990D0
Authority
DK
Denmark
Prior art keywords
conjugates
cell epitopes
immunoconjugates
oligopeptides
well
Prior art date
Application number
DK182990A
Other languages
English (en)
Other versions
DK182990A (da
DK174416B1 (da
Inventor
Garvin Bixler
Subramonia Pillai
Richard Insel
Original Assignee
Praxis Biolog Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Praxis Biolog Inc filed Critical Praxis Biolog Inc
Publication of DK182990D0 publication Critical patent/DK182990D0/da
Publication of DK182990A publication Critical patent/DK182990A/da
Application granted granted Critical
Publication of DK174416B1 publication Critical patent/DK174416B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Optical Couplings Of Light Guides (AREA)
DK199001829A 1988-02-01 1990-07-31 Oligopeptider, immunogene konjugater heraf med et antigen samt vacciner indeholdende disse konjugater DK174416B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15068888A 1988-02-01 1988-02-01
PCT/US1989/000388 WO1989006974A2 (en) 1988-02-01 1989-01-31 T-cell epitope as carriers molecule for conjugate vaccines

Publications (3)

Publication Number Publication Date
DK182990D0 true DK182990D0 (da) 1990-07-31
DK182990A DK182990A (da) 1990-07-31
DK174416B1 DK174416B1 (da) 2003-02-17

Family

ID=22535596

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199001829A DK174416B1 (da) 1988-02-01 1990-07-31 Oligopeptider, immunogene konjugater heraf med et antigen samt vacciner indeholdende disse konjugater

Country Status (10)

Country Link
EP (1) EP0399001B1 (da)
JP (1) JP2921574B2 (da)
AT (1) ATE109008T1 (da)
AU (1) AU634153B2 (da)
CA (2) CA1340958C (da)
DE (1) DE68917126T2 (da)
DK (1) DK174416B1 (da)
FI (1) FI104374B (da)
NO (1) NO179164C (da)
WO (1) WO1989006974A2 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6642390A (en) * 1989-10-27 1991-05-31 Arch Development Corporation Methods and compositions for promoting immunopotentiation
GB8924438D0 (en) * 1989-10-31 1989-12-20 Hoffmann La Roche Vaccine composition
DE4192335C2 (de) * 1990-09-18 1996-02-08 Biotech Australia Pty Ltd T-Zell-Epitope
WO1993011157A1 (en) * 1991-11-27 1993-06-10 The Council Of The Queensland Institute Of Medical Research MALARIAL VACCINE AND PEPTIDES COMPRISING HUMAN T-CELL EPITOPE OF CIRCUMSPOROZOITE PROTEIN OF $i(P.VIVAX)
IL105503A (en) * 1992-04-28 1999-05-09 Astra Ab Carbon peptide couplets capable of eliciting an immune response of T cells
IL106436A0 (en) * 1992-07-22 1993-11-15 Proteus Molecular Design Synthetic polypeptides and their use
US6680182B1 (en) * 1992-07-31 2004-01-20 Acambis Research Limited Expression of recombinant fusion proteins in attenuated bacteria
CN1091138A (zh) 1992-08-27 1994-08-24 迪金研究有限公司 疫苗
DK140992D0 (da) * 1992-11-24 1992-11-24 Ole Buchardt Fremgangsmaade til frembringelse af antistoffer mod haptener og andre b-celle-antigener, antistoffer opnaaet ved fremgangsmaaden og anvendelse af disse antistoffer til fremstilling af vacciner, isaer til veterinaermedicinsk brug
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
GB9401787D0 (en) 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccine compositions
ATE215124T1 (de) * 1993-07-30 2002-04-15 Medeva Holdings Bv Rekombinante tetc-fusionsprotein enthaltene impfstoffzusammensetzungen
GB9401795D0 (en) * 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccines
GB2295394B (en) * 1994-01-31 1997-09-24 Medeva Holdings Bv DNA encoding a fusion protein comprising the C fragment of tetanus toxin
US5725860A (en) * 1994-03-07 1998-03-10 Auckland Uniservices Limited Method for reducing the risk of developing diabetes
US5840307A (en) * 1995-03-31 1998-11-24 Immulogic Pharmacuetical Corp. Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation
DK1329226T3 (da) * 1995-03-31 2007-09-24 Xenova Res Ltd Haptenbærerkonjugater til anvendelse i behandling af stofmisbrug
US5843462A (en) * 1995-11-30 1998-12-01 Regents Of The University Of Minnesota Diphtheria toxin epitopes
ATE220718T1 (de) 1996-04-19 2002-08-15 Us Gov Sec Health Mutierte ras peptide zur zeugung von cd8+ zytitoxischen t lymphoizyten
US7709002B1 (en) 1996-04-19 2010-05-04 The United States Of America As Represented By The Department Of Health And Human Services Mutated ras peptides for generation of CD8+Cytotoxic T lymphocytes
GB9713156D0 (en) * 1997-06-20 1997-08-27 Microbiological Res Authority Vaccines
TWI229679B (en) 1998-06-20 2005-03-21 United Biomedical Inc Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens
US6025468A (en) * 1998-06-20 2000-02-15 United Biomedical, Inc. Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens including immunogenic LHRH peptides
DE19856052A1 (de) * 1998-12-04 2000-06-08 Deutsches Krebsforsch Konjugat zur Anreicherung in neuronalen Zellen
US6663861B2 (en) 2000-11-09 2003-12-16 Antibodyshop A/S Method of producing antibodies by immunization with conjugates of molecules coupled to charge-modified proteins
EP2356133B1 (en) 2008-10-10 2019-07-31 Zera Intein Protein Solutions, S.L. Recombinant protein bodies as immunogen-specific adjuvants
EP2411039A4 (en) * 2009-03-23 2015-05-06 Brigham & Womens Hospital Glycoconjugate VACCINES
EP2418284A1 (en) 2010-08-13 2012-02-15 ERA Biotech, S.A. Protein body-inducing polypeptide sequences
EP2870974A1 (en) * 2013-11-08 2015-05-13 Novartis AG Salmonella conjugate vaccines
US9815886B2 (en) 2014-10-28 2017-11-14 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
ES3024474T3 (en) 2016-12-30 2025-06-04 Vaxcyte Inc Polypeptide-antigen conjugates with non-natural amino acids
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
WO2020010016A1 (en) 2018-07-04 2020-01-09 Sutrovax, Inc. Self-adjuvanted immunogenic conjugates
CN112543649B (zh) 2018-07-04 2026-03-31 Vaxcyte公司 免疫原性缀合物的改进
WO2020010000A1 (en) 2018-07-04 2020-01-09 Sutrovax, Inc. Improved methods for the preparation of immunogenic conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902506A (en) * 1983-07-05 1990-02-20 The University Of Rochester Immunogenic conjugates
US4808700A (en) * 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
NZ214503A (en) * 1984-12-20 1990-02-26 Merck & Co Inc Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates

Also Published As

Publication number Publication date
DE68917126D1 (de) 1994-09-01
NO902909D0 (no) 1990-06-29
ATE109008T1 (de) 1994-08-15
WO1989006974A2 (en) 1989-08-10
DE68917126T2 (de) 1995-02-02
NO179164B (no) 1996-05-13
NO179164C (no) 1996-08-21
EP0399001A1 (en) 1990-11-28
EP0399001B1 (en) 1994-07-27
JPH03502691A (ja) 1991-06-20
CA1340958C (en) 2000-04-11
JP2921574B2 (ja) 1999-07-19
FI104374B (fi) 2000-01-14
CA1340956C (en) 2000-04-11
NO902909L (no) 1990-08-27
AU3065489A (en) 1989-08-25
AU634153B2 (en) 1993-02-18
WO1989006974A3 (en) 1989-08-24
DK182990A (da) 1990-07-31
FI903292A0 (fi) 1990-06-29
DK174416B1 (da) 2003-02-17

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