ATE284897T1 - Selfantigen-impfstoffe zur behandlung von b-zell lymphomen und sonstigen krebsen - Google Patents

Selfantigen-impfstoffe zur behandlung von b-zell lymphomen und sonstigen krebsen

Info

Publication number
ATE284897T1
ATE284897T1 AT00973516T AT00973516T ATE284897T1 AT E284897 T1 ATE284897 T1 AT E284897T1 AT 00973516 T AT00973516 T AT 00973516T AT 00973516 T AT00973516 T AT 00973516T AT E284897 T1 ATE284897 T1 AT E284897T1
Authority
AT
Austria
Prior art keywords
polypeptide
plant
lymphoma
tumor
produced
Prior art date
Application number
AT00973516T
Other languages
English (en)
Inventor
Stephen J Reinl
Thomas H Turpen
Alison A Mccormick
Daniel Tuse
John A Lindbo
Original Assignee
Large Scale Biology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Large Scale Biology Corp filed Critical Large Scale Biology Corp
Application granted granted Critical
Publication of ATE284897T1 publication Critical patent/ATE284897T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/13Immunoglobulins specific features characterized by their source of isolation or production isolated from plants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT00973516T 2000-03-10 2000-10-13 Selfantigen-impfstoffe zur behandlung von b-zell lymphomen und sonstigen krebsen ATE284897T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52290000A 2000-03-10 2000-03-10
PCT/US2000/028362 WO2001068682A1 (en) 2000-03-10 2000-10-13 Self antigen vaccines for treating b cell lymphomas and other cancers

Publications (1)

Publication Number Publication Date
ATE284897T1 true ATE284897T1 (de) 2005-01-15

Family

ID=24082838

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00973516T ATE284897T1 (de) 2000-03-10 2000-10-13 Selfantigen-impfstoffe zur behandlung von b-zell lymphomen und sonstigen krebsen

Country Status (8)

Country Link
EP (1) EP1263779B1 (de)
JP (1) JP2003527399A (de)
AT (1) ATE284897T1 (de)
AU (2) AU2001212019B2 (de)
CA (1) CA2402086A1 (de)
DE (1) DE60016806T2 (de)
WO (1) WO2001068682A1 (de)
ZA (1) ZA200206798B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1571211B1 (de) * 2002-11-22 2010-01-20 Chugai Seiyaku Kabushiki Kaisha Antikörper gegen geschädigtes gewebe
US8008076B2 (en) 2004-04-27 2011-08-30 Chugai Seiyaku Kabushiki Kaisha Method of producing a nucleic acid encoding an antibody
US20100124741A1 (en) * 2008-11-18 2010-05-20 Quest Disgnostics Investments Incorporated METHODS FOR DETECTING IgH/BCL-1 CHROMOSOMAL TRANSLOCATION
CN107090459A (zh) 2011-07-12 2017-08-25 埃克斯生物科技公司 鉴定亲和力成熟的人类抗体

Also Published As

Publication number Publication date
EP1263779A1 (de) 2002-12-11
WO2001068682A1 (en) 2001-09-20
CA2402086A1 (en) 2001-09-20
AU2001212019B2 (en) 2006-12-14
AU1201901A (en) 2001-09-24
DE60016806T2 (de) 2005-12-15
DE60016806D1 (de) 2005-01-20
ZA200206798B (en) 2003-08-26
JP2003527399A (ja) 2003-09-16
EP1263779B1 (de) 2004-12-15

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