DK183385A - Apovincaminolderivater eller syreadditionssalte deraf, deres fremstilling og anvendelser som farmaceutika - Google Patents
Apovincaminolderivater eller syreadditionssalte deraf, deres fremstilling og anvendelser som farmaceutika Download PDFInfo
- Publication number
- DK183385A DK183385A DK183385A DK183385A DK183385A DK 183385 A DK183385 A DK 183385A DK 183385 A DK183385 A DK 183385A DK 183385 A DK183385 A DK 183385A DK 183385 A DK183385 A DK 183385A
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceuticals
- applications
- preparation
- additional salts
- acid additional
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
hvor er H, N02 eller halogen, R2 er eventuelt substitueret alkyl eller phenyl, og er H, OH eller OR,., eller og R^ danner sammen med valensbinding, og R^ eventuelt er substitueret alkanoyl eller benzoyl, idet dog R3 og R4 ikke er en valensbinding, hvis er H, og R2 er 3,4,5--trimethoxyphenyl, og idet dog R^ ikke er H, N02 eller Br, hvis R3 og r4 begge er H, og R2 er 3,4,5-trimethoxyphenyl, og syreadditionssalte deraf fremstilles ved et par forskellige fremgangsmåder.
Forbindelserne med formel (I) er farmaceutisk aktive, især til behandling af hudsygdomme.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU158284 | 1984-04-25 | ||
| HU841582A HU192013B (en) | 1984-04-25 | 1984-04-25 | Process for production of new aporincavinol esther derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK183385D0 DK183385D0 (da) | 1985-04-24 |
| DK183385A true DK183385A (da) | 1985-10-26 |
Family
ID=10955131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK183385A DK183385A (da) | 1984-04-25 | 1985-04-24 | Apovincaminolderivater eller syreadditionssalte deraf, deres fremstilling og anvendelser som farmaceutika |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4680397A (da) |
| JP (1) | JPS60260575A (da) |
| AR (1) | AR242387A1 (da) |
| AT (1) | AT389307B (da) |
| BE (1) | BE902259A (da) |
| CA (1) | CA1265520A (da) |
| CH (1) | CH665418A5 (da) |
| DE (1) | DE3514669A1 (da) |
| DK (1) | DK183385A (da) |
| FI (1) | FI851612A7 (da) |
| FR (1) | FR2563520B1 (da) |
| GB (1) | GB2158066B (da) |
| HU (1) | HU192013B (da) |
| IT (1) | IT1208533B (da) |
| NL (1) | NL8501178A (da) |
| SE (1) | SE464708B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU192013B (en) * | 1984-04-25 | 1987-04-28 | Richter Gedeon Vegyeszet | Process for production of new aporincavinol esther derivatives |
| HU191938B (en) * | 1984-07-11 | 1987-04-28 | Andras Vedres | Process for production of new derivatives of 9 and 11 nitro-apovincamin acid |
| CN107595843A (zh) * | 2017-10-10 | 2018-01-19 | 南京中医药大学 | 一类长春胺衍生物及其治疗2型糖尿病的用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2035784A1 (en) * | 1969-03-27 | 1970-12-24 | Olivier Louisette | Vincamine derivs with therapeutic propert- - ies |
| BE790837A (fr) * | 1971-11-03 | 1973-02-15 | Richter Gedeon Vegeon Vegyesze | Nouveaux esters alcaloides utiles comme vasodilatateurs cerebraux et leur procede de preparation |
| US4035370A (en) * | 1971-11-03 | 1977-07-12 | Richter Gedeon Vegyeszeti Gyar Rt. | Alkaloid esters |
| HU166476B (da) * | 1972-12-15 | 1975-03-28 | ||
| HU170888B (hu) * | 1975-06-10 | 1977-09-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh eburnameninov |
| HU171662B (hu) * | 1975-07-18 | 1978-02-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov |
| US4285949A (en) * | 1978-12-11 | 1981-08-25 | Omnichem Societe Anonyme | Vincamine derivatives, their preparation and therapeutical use |
| HU183325B (en) * | 1981-02-11 | 1984-04-28 | Richter Gedeon Vegyeszet | Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoates substituted with a nitro group |
| HU183323B (en) * | 1981-02-11 | 1984-04-28 | Richter Gedeon Vegyeszet | Process for producing 17,18-dihydro-apovincaminol-3-comma down comma aaove-4-comma down comma above-5-comma down comma aaove-trimethoxy-benzoate and acid additional salts thereof |
| HU183324B (en) * | 1981-02-11 | 1984-04-28 | Richter Gedeon Vegyeszet | Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoate and acid addition salts thereof |
| HU183326B (en) * | 1981-02-11 | 1984-04-28 | Richter Gedeon Vegyeszet | Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoates substituted in the a ring and acid addition salts thereof |
| SE449863B (sv) * | 1981-02-11 | 1987-05-25 | Richter Gedeon Vegyeszet | Apovinkaminolderivat, framstellning och farmaceutisk beredning derav |
| HU192013B (en) * | 1984-04-25 | 1987-04-28 | Richter Gedeon Vegyeszet | Process for production of new aporincavinol esther derivatives |
-
1984
- 1984-04-25 HU HU841582A patent/HU192013B/hu not_active IP Right Cessation
-
1985
- 1985-04-22 CH CH1720/85A patent/CH665418A5/de not_active IP Right Cessation
- 1985-04-23 DE DE19853514669 patent/DE3514669A1/de not_active Withdrawn
- 1985-04-23 BE BE0/214892A patent/BE902259A/fr not_active IP Right Cessation
- 1985-04-23 NL NL8501178A patent/NL8501178A/nl not_active Application Discontinuation
- 1985-04-23 CA CA000479869A patent/CA1265520A/en not_active Expired - Lifetime
- 1985-04-23 FR FR8506123A patent/FR2563520B1/fr not_active Expired
- 1985-04-24 IT IT8520483A patent/IT1208533B/it active
- 1985-04-24 DK DK183385A patent/DK183385A/da not_active Application Discontinuation
- 1985-04-24 FI FI851612A patent/FI851612A7/fi not_active Application Discontinuation
- 1985-04-24 SE SE8501993A patent/SE464708B/sv not_active IP Right Cessation
- 1985-04-24 AT AT0122885A patent/AT389307B/de not_active IP Right Cessation
- 1985-04-24 AR AR85300172A patent/AR242387A1/es active
- 1985-04-24 JP JP60086607A patent/JPS60260575A/ja active Pending
- 1985-04-24 GB GB08510370A patent/GB2158066B/en not_active Expired
- 1985-04-25 US US06/727,130 patent/US4680397A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT8520483A0 (it) | 1985-04-24 |
| SE8501993D0 (sv) | 1985-04-24 |
| ATA122885A (de) | 1989-04-15 |
| SE464708B (sv) | 1991-06-03 |
| SE8501993L (sv) | 1985-10-26 |
| NL8501178A (nl) | 1985-11-18 |
| DK183385D0 (da) | 1985-04-24 |
| DE3514669A1 (de) | 1985-10-31 |
| HU192013B (en) | 1987-04-28 |
| CA1265520A (en) | 1990-02-06 |
| IT1208533B (it) | 1989-07-10 |
| AT389307B (de) | 1989-11-27 |
| HUT37428A (en) | 1985-12-28 |
| FR2563520B1 (fr) | 1988-11-18 |
| GB8510370D0 (en) | 1985-05-30 |
| JPS60260575A (ja) | 1985-12-23 |
| BE902259A (fr) | 1985-08-16 |
| FI851612L (fi) | 1985-10-26 |
| CH665418A5 (de) | 1988-05-13 |
| GB2158066B (en) | 1988-04-07 |
| FR2563520A1 (fr) | 1985-10-31 |
| FI851612A7 (fi) | 1985-10-26 |
| AR242387A1 (es) | 1993-03-31 |
| FI851612A0 (fi) | 1985-04-24 |
| US4680397A (en) | 1987-07-14 |
| GB2158066A (en) | 1985-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |