DK183589A - Farmaceutisk middel indeholdende en 12-leddet macrolid-forbindelse og fremgangsmaade til fremstilling heraf - Google Patents

Farmaceutisk middel indeholdende en 12-leddet macrolid-forbindelse og fremgangsmaade til fremstilling heraf

Info

Publication number
DK183589A
DK183589A DK183589A DK183589A DK183589A DK 183589 A DK183589 A DK 183589A DK 183589 A DK183589 A DK 183589A DK 183589 A DK183589 A DK 183589A DK 183589 A DK183589 A DK 183589A
Authority
DK
Denmark
Prior art keywords
macrolid
preparing
joint
procedure
compound
Prior art date
Application number
DK183589A
Other languages
English (en)
Other versions
DK183589D0 (da
Inventor
Jaswant Singh Gidda
Herbert Andrew Kirst
David Wayne Robertson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK183589D0 publication Critical patent/DK183589D0/da
Publication of DK183589A publication Critical patent/DK183589A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK183589A 1988-04-18 1989-04-17 Farmaceutisk middel indeholdende en 12-leddet macrolid-forbindelse og fremgangsmaade til fremstilling heraf DK183589A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/182,645 US4920102A (en) 1988-04-18 1988-04-18 Method for treating gastrointestinal disorders

Publications (2)

Publication Number Publication Date
DK183589D0 DK183589D0 (da) 1989-04-17
DK183589A true DK183589A (da) 1989-10-19

Family

ID=22669415

Family Applications (1)

Application Number Title Priority Date Filing Date
DK183589A DK183589A (da) 1988-04-18 1989-04-17 Farmaceutisk middel indeholdende en 12-leddet macrolid-forbindelse og fremgangsmaade til fremstilling heraf

Country Status (22)

Country Link
US (1) US4920102A (da)
EP (1) EP0349100B1 (da)
JP (1) JPH0825882B2 (da)
KR (1) KR970009580B1 (da)
CN (1) CN1023017C (da)
AR (1) AR244699A1 (da)
AT (1) ATE139782T1 (da)
AU (1) AU616746B2 (da)
CA (1) CA1328257C (da)
DE (1) DE68926728T2 (da)
DK (1) DK183589A (da)
ES (1) ES2088388T3 (da)
GR (1) GR3020604T3 (da)
HU (1) HU206365B (da)
IE (1) IE72969B1 (da)
IL (1) IL89996A (da)
MX (1) MX15701A (da)
NZ (1) NZ228768A (da)
PH (1) PH26391A (da)
PT (1) PT90293B (da)
RU (1) RU2086560C1 (da)
ZA (1) ZA892801B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US5068221A (en) * 1989-05-09 1991-11-26 Mathias John R Treatment of motility disorders with a gnrh analog
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
US5523401A (en) * 1991-04-09 1996-06-04 Abbott Laboratories Macrocyclic lactam prokinetic agents
CA2103913A1 (en) * 1991-04-09 1992-10-10 Leslie A. Freiberg Macrocyclic lactam prokinetic agents
DE4200145A1 (de) * 1992-01-07 1993-07-08 Kali Chemie Pharma Gmbh 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
HK1010054A1 (en) * 1992-01-21 1999-06-11 Abbott Laboratories 4"-deoxyerythromycin derivatives
CA2092045C (en) * 1992-03-19 2004-08-10 Setsuo Harada Erythromycin derivatives, preparation and use thereof
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
US5972898A (en) * 1998-03-27 1999-10-26 Abbott Laboratories 3',3-N-bis-substituted macrolide LHRH antagonists
US5955440A (en) * 1998-03-27 1999-09-21 Abbott Laboratories Macrolide LHRH antagonists
US6020521A (en) * 1998-08-26 2000-02-01 Abbott Laboratories Macrolide LHRH antagonists
US6387885B1 (en) 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6469030B2 (en) 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
ATE321770T1 (de) 2000-08-17 2006-04-15 Kitasato Inst Pseudoerythromycin-derivate
GB0123400D0 (en) * 2001-09-28 2001-11-21 Novartis Ag Organic compounds
RU2202351C1 (ru) * 2001-11-29 2003-04-20 Дальневосточный государственный медицинский университет Способ коррекции гастропареза после органосохраняющих операций на желудке
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
CN1280302C (zh) * 2002-10-29 2006-10-18 社团法人北里研究所 对抗真菌活性有增强作用的大环内酯衍生物
US7521420B2 (en) 2003-06-18 2009-04-21 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
JP2009518396A (ja) * 2005-12-08 2009-05-07 ファイザー・インク エリスロマイシン化合物の３’−ジメチルアミノ基を脱メチルする方法
EP2054429B1 (en) 2006-09-11 2013-11-06 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
FR2995605B1 (fr) * 2012-09-18 2014-09-19 Sanofi Sa Derives de macrolides, leur preparation et leur application therapeutique.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
EP0215355B1 (en) * 1985-08-31 1994-04-06 Kitasato Kenkyusho Erythromycin derivative and process for preparing the same
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides

Also Published As

Publication number Publication date
HU206365B (en) 1992-10-28
NZ228768A (en) 1990-10-26
PT90293B (pt) 1994-07-29
DE68926728D1 (de) 1996-08-01
PT90293A (pt) 1989-11-10
EP0349100A2 (en) 1990-01-03
AU3310789A (en) 1989-10-19
MX15701A (es) 1993-11-01
IL89996A0 (en) 1989-12-15
ATE139782T1 (de) 1996-07-15
US4920102A (en) 1990-04-24
CN1037517A (zh) 1989-11-29
KR970009580B1 (en) 1997-06-14
EP0349100B1 (en) 1996-06-26
HUT49625A (en) 1989-10-30
IL89996A (en) 1994-08-26
IE72969B1 (en) 1997-05-07
CN1023017C (zh) 1993-12-08
CA1328257C (en) 1994-04-05
DK183589D0 (da) 1989-04-17
AU616746B2 (en) 1991-11-07
GR3020604T3 (en) 1996-10-31
EP0349100A3 (en) 1991-11-13
KR900016220A (ko) 1990-11-12
IE891224L (en) 1989-10-18
RU2086560C1 (ru) 1997-08-10
DE68926728T2 (de) 1996-11-28
ES2088388T3 (es) 1996-08-16
PH26391A (en) 1992-07-02
JPH01311096A (ja) 1989-12-15
AR244699A1 (es) 1993-11-30
JPH0825882B2 (ja) 1996-03-13
ZA892801B (en) 1990-12-28

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