DK1848406T3 - Fast, penoral lægemiddelform til kontraception, der indeholder dienogest og ethynylestradiol - Google Patents

Fast, penoral lægemiddelform til kontraception, der indeholder dienogest og ethynylestradiol

Info

Publication number: DK1848406T3
Authority: DK; Denmark
Prior art keywords: dienogest; solid; penal; formulation; ethinyl estradiol
Prior art date: 2005-02-15

Application number

DK06706961T

Other languages

Danish (da)

English (en)

Inventor

Sabine Fricke

Hagen Gerecke

Ralf Ladwig

Alexander Buske

Harald Raethe

Original Assignee

Jenapharm Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-02-15

Filing date

2006-02-15

Publication date

2008-09-15

2005-02-15 Priority claimed from EP05003181A external-priority patent/EP1690529A1/de

2005-02-15 Priority claimed from EP05003179A external-priority patent/EP1690543A1/de

2006-02-15 Application filed by Jenapharm Gmbh filed Critical Jenapharm Gmbh

2008-09-15 Application granted granted Critical

2008-09-15 Publication of DK1848406T3 publication Critical patent/DK1848406T3/da

Links

BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 title abstract 4
AZFLJNIPTRTECV-FUMNGEBKSA-N dienogest Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@](CC3)(O)CC#N)CC3)C3=C21 AZFLJNIPTRTECV-FUMNGEBKSA-N 0.000 title abstract 4
229960003309 dienogest Drugs 0.000 title abstract 4
229960002568 ethinylestradiol Drugs 0.000 title abstract 3
239000007787 solid Substances 0.000 title abstract 2
238000009472 formulation Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 abstract 2
239000003433 contraceptive agent Substances 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gynecology & Obstetrics (AREA)
Organic Chemistry (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Orthopedics, Nursing, And Contraception (AREA)

DK06706961T 2005-02-15 2006-02-15 Fast, penoral lægemiddelform til kontraception, der indeholder dienogest og ethynylestradiol DK1848406T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP05003181A EP1690529A1 (de)	2005-02-15	2005-02-15	Feste perorale Arzneiform zur Kontrazeption, die Dienogest und Ethinylestradiol enthält
EP05003179A EP1690543A1 (de)	2005-02-15	2005-02-15	Pharmazeutisches Präparat zur Kontrazeption
PCT/EP2006/001358 WO2006087177A2 (de)	2005-02-15	2006-02-15	Feste perorale arzneiform zur kontrazeption, die dienogest und ethinylestradiol enthält

Publications (1)

Publication Number	Publication Date
DK1848406T3 true DK1848406T3 (da)	2008-09-15

Family

ID=37951746

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK06706961T DK1848406T3 (da)	2005-02-15	2006-02-15	Fast, penoral lægemiddelform til kontraception, der indeholder dienogest og ethynylestradiol

Country Status (20)

Country	Link
EP (1)	EP1848406B1 (pl)
JP (1)	JP2008527019A (pl)
KR (1)	KR20070087141A (pl)
AT (1)	ATE395047T1 (pl)
AU (1)	AU2006215822B2 (pl)
BR (1)	BRPI0606297A2 (pl)
CA (1)	CA2594939A1 (pl)
CY (1)	CY1108265T1 (pl)
DE (1)	DE502006000771D1 (pl)
DK (1)	DK1848406T3 (pl)
EA (1)	EA200701389A1 (pl)
ES (1)	ES2310907T3 (pl)
HR (1)	HRP20080394T3 (pl)
IL (1)	IL184257A0 (pl)
NO (1)	NO20072893L (pl)
PL (1)	PL1848406T3 (pl)
PT (1)	PT1848406E (pl)
RS (1)	RS50597B (pl)
SI (1)	SI1848406T1 (pl)
WO (1)	WO2006087177A2 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009015766A1 (de) *	2007-07-31	2009-02-05	Bayer Schering Pharma Aktiengesellschaft	Einphasisches pharmazeutisches kombinationspräparat (dienogest und ethinylestradiol) zur oralen therapie der regulierung des blutdruckes
EP2020235A1 (de) *	2007-07-31	2009-02-04	Bayer Schering Pharma AG	einphasisches pharmazeutisches kombinationspräparat (dienogest und ethinylestradiol) zur oralen therapie der regulierung des blutdruckes
JP6759478B2 (ja) *	2019-02-13	2020-09-23	富士製薬工業株式会社	経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤
EP3954364A1 (en) *	2020-08-14	2022-02-16	Chemo Research, S.L.	New modified release oral contraceptive composition
KR102652671B1 (ko)	2023-12-26	2024-03-29	주식회사 스몰랩	피임 마이크로니들용 미립구 조성물 및 이를 포함한 피임 마이크로니들
US20260021110A1 (en)	2024-07-18	2026-01-22	Chemo Research, S.L.	Methods of oral contraception by controlled release of dienogest and ethynyl estradiol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19525017A1 (de) *	1995-06-28	1997-01-02	Schering Ag	Pharmazeutisches Kombinatonspräparat, Kit und Methode zur hormonalen Kontrazeption
KR100518102B1 (ko) *	1996-07-26	2005-10-04	와이어쓰	프로게스틴과 에스트로겐의 혼합물을 포함하는 단일상 피임약 키트

2006
- 2006-02-15 JP JP2007551647A patent/JP2008527019A/ja not_active Withdrawn
- 2006-02-15 EA EA200701389A patent/EA200701389A1/ru unknown
- 2006-02-15 AT AT06706961T patent/ATE395047T1/de active
- 2006-02-15 EP EP06706961A patent/EP1848406B1/de not_active Expired - Lifetime
- 2006-02-15 PT PT06706961T patent/PT1848406E/pt unknown
- 2006-02-15 SI SI200630062T patent/SI1848406T1/sl unknown
- 2006-02-15 KR KR1020077016400A patent/KR20070087141A/ko not_active Abandoned
- 2006-02-15 RS RSP-2008/0358A patent/RS50597B/sr unknown
- 2006-02-15 HR HR20080394T patent/HRP20080394T3/xx unknown
- 2006-02-15 AU AU2006215822A patent/AU2006215822B2/en not_active Ceased
- 2006-02-15 PL PL06706961T patent/PL1848406T3/pl unknown
- 2006-02-15 WO PCT/EP2006/001358 patent/WO2006087177A2/de not_active Ceased
- 2006-02-15 DE DE502006000771T patent/DE502006000771D1/de not_active Expired - Lifetime
- 2006-02-15 BR BRPI0606297-0A patent/BRPI0606297A2/pt not_active Application Discontinuation
- 2006-02-15 CA CA002594939A patent/CA2594939A1/en not_active Abandoned
- 2006-02-15 ES ES06706961T patent/ES2310907T3/es not_active Expired - Lifetime
- 2006-02-15 DK DK06706961T patent/DK1848406T3/da active
2007
- 2007-06-06 NO NO20072893A patent/NO20072893L/no not_active Application Discontinuation
- 2007-06-27 IL IL184257A patent/IL184257A0/en unknown
2008
- 2008-08-14 CY CY20081100871T patent/CY1108265T1/el unknown

Also Published As

Publication number	Publication date
PL1848406T3 (pl)	2009-06-30
CY1108265T1 (el)	2014-02-12
WO2006087177B1 (de)	2007-10-11
HRP20080394T3 (hr)	2008-11-30
WO2006087177A3 (de)	2007-08-30
AU2006215822B2 (en)	2008-09-04
ES2310907T3 (es)	2009-01-16
EA200701389A1 (ru)	2008-02-28
SI1848406T1 (sl)	2008-10-31
EP1848406B1 (de)	2008-05-14
EP1848406A2 (de)	2007-10-31
RS50597B (sr)	2010-05-07
KR20070087141A (ko)	2007-08-27
ATE395047T1 (de)	2008-05-15
IL184257A0 (en)	2007-10-31
JP2008527019A (ja)	2008-07-24
WO2006087177A2 (de)	2006-08-24
CA2594939A1 (en)	2006-08-24
WO2006087177A8 (de)	2007-05-24
NO20072893L (no)	2007-09-12
AU2006215822A1 (en)	2006-08-24
PT1848406E (pt)	2008-08-21
BRPI0606297A2 (pt)	2009-06-09
DE502006000771D1 (de)	2008-06-26

Publication	Publication Date	Title
HRP20070188B1 (hr)	2015-06-19	Farmaceutska kombinacija etinilestradiola i drospirenona za upotrebu kao kontracepcijskog sredstva
EA200900491A1 (ru)	2009-10-30	Применение эстрадиола валерата или 17в-эстрадиола в комбинации с диеногестом для перорального лечения для поддержания и/или повышения полового влечения у особи женского пола
MX2008011074A (es)	2008-09-10	Metodo anticonceptivo oral multifasico de ciclo prolongado.
CA2420292A1 (en)	2002-03-21	Contraception process and administration form for the same
NO327588B1 (no)	2009-08-31	Farmasoytisk sammensetning og preparat omfattende etinylostradiol og drospirenon for anvendelse som antikonsepsjonsmiddel
HRP20090418T1 (hr)	2009-09-30	Farmaceutski pripravak koji sadrži gestagene i/ili estrogene i 5-metil-(6s)-tetrahidrofolate
CY1108265T1 (el)	2014-02-12	Στερεη διαστοματικη φαρμακευτικη μορφη για αντισυλληψη
UA85003C2 (ru)	2008-12-10	Твердая лекарственная форма для контрацепции
TW200638951A (en)	2006-11-16	Solid oral pharmaceutical form for contraception
HRP20090256T1 (en)	2009-06-30	Use of estradiolvalerate and dienogest for oral treatment of dysfunctional uterine bleeding in a contraceptive method
WO2005092441A3 (en)	2006-08-31	Extended cycle multiphasic oral contraceptive method
WO2008017331A3 (de)	2009-01-08	Perorale arzneiform mit dienogest und ethinylestradiol zur kontrazeption
TH80558A (th)	2006-10-19	รูปแบบยาทางช่องปากชนิดแข็งสำหรับการคุมกำเนิด
DK1937274T3 (da)	2012-06-18	Anvendelse af estradiolvalerat i kombination med dienogest til oral behandling af dysfunktionel uterin blødning i enhed med en oral kontraception
PE20091020A1 (es)	2009-08-15	Uso de un gestageno en combinacion con un estrogeno y uno o varios excipientes/portadores farmaceuticamente aceptables para la anticoncepcion oral sin lactosa
UY29378A1 (es)	2006-08-31	Preparación farmaceutica para la anticoncepción oral
ECSP003721A (es)	2002-05-23	Una composicion farmaceutica para ser usada como anticonceptivo
JO2213B1 (en)	2004-10-07	A pharmaceutical composition for use as a contraceptive method