DK1852433T3 - Carbazolderivat, solvate deraf eller farmaceutisk acceptabelt salt deraf - Google Patents

Carbazolderivat, solvate deraf eller farmaceutisk acceptabelt salt deraf

Info

Publication number
DK1852433T3
DK1852433T3 DK05799893.2T DK05799893T DK1852433T3 DK 1852433 T3 DK1852433 T3 DK 1852433T3 DK 05799893 T DK05799893 T DK 05799893T DK 1852433 T3 DK1852433 T3 DK 1852433T3
Authority
DK
Denmark
Prior art keywords
group
carbazole derivatives
solvates
pharmaceutically acceptable
acceptable salts
Prior art date
Application number
DK05799893.2T
Other languages
Danish (da)
English (en)
Inventor
Masakazu Murata
Yoshihiko Itokazu
Ryu Nakao
Original Assignee
Zeria Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeria Pharm Co Ltd filed Critical Zeria Pharm Co Ltd
Application granted granted Critical
Publication of DK1852433T3 publication Critical patent/DK1852433T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK05799893.2T 2004-10-29 2005-10-28 Carbazolderivat, solvate deraf eller farmaceutisk acceptabelt salt deraf DK1852433T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004316872 2004-10-29
PCT/JP2005/020250 WO2006046779A1 (ja) 2004-10-29 2005-10-28 カルバゾール誘導体、その溶媒和物、又は薬学的に許容されるその塩

Publications (1)

Publication Number Publication Date
DK1852433T3 true DK1852433T3 (da) 2012-01-30

Family

ID=36227999

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05799893.2T DK1852433T3 (da) 2004-10-29 2005-10-28 Carbazolderivat, solvate deraf eller farmaceutisk acceptabelt salt deraf

Country Status (16)

Country Link
US (1) US8329913B2 (2)
EP (1) EP1852433B1 (2)
JP (1) JP3997491B2 (2)
KR (1) KR101223820B1 (2)
CN (1) CN101048402B (2)
AT (1) ATE534646T1 (2)
AU (1) AU2005297800B2 (2)
CA (1) CA2585642C (2)
CY (1) CY1112649T1 (2)
DK (1) DK1852433T3 (2)
ES (1) ES2378177T3 (2)
PL (1) PL1852433T3 (2)
PT (1) PT1852433E (2)
SI (1) SI1852433T1 (2)
TW (1) TW200635922A (2)
WO (1) WO2006046779A1 (2)

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CA2646277C (en) 2006-03-23 2016-01-12 The Penn State Research Foundation Heart assist device with expandable impeller pump
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
AU2008279447A1 (en) 2007-07-19 2009-01-29 Metabolex, Inc. N-azacyclic substituted pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives as agonists of the RUP3 or GPR119 receptor for the treatment of diabetes and metabolic disorders
WO2011003043A1 (en) 2009-07-01 2011-01-06 The Penn State Research Foundation Blood pump with expandable cannula
US8410127B2 (en) 2009-10-01 2013-04-02 Metabolex, Inc. Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
CN109674753A (zh) 2010-06-23 2019-04-26 希玛贝治疗股份有限公司 固态分散体
CN102382037B (zh) * 2010-09-03 2016-01-20 中国医学科学院药物研究所 苯丙酸类化合物及其制法和药物用途
US8485961B2 (en) 2011-01-05 2013-07-16 Thoratec Corporation Impeller housing for percutaneous heart pump
US8597170B2 (en) 2011-01-05 2013-12-03 Thoratec Corporation Catheter pump
US8591393B2 (en) 2011-01-06 2013-11-26 Thoratec Corporation Catheter pump
WO2012094641A2 (en) 2011-01-06 2012-07-12 Thoratec Corporation Percutaneous heart pump
GB2504176A (en) 2012-05-14 2014-01-22 Thoratec Corp Collapsible impeller for catheter pump
DE102013008159A1 (de) 2012-05-14 2013-11-14 Thoratec Corporation Mantelsystem für Katheterpumpe
US9446179B2 (en) 2012-05-14 2016-09-20 Thoratec Corporation Distal bearing support
US8721517B2 (en) 2012-05-14 2014-05-13 Thoratec Corporation Impeller for catheter pump
US9327067B2 (en) 2012-05-14 2016-05-03 Thoratec Corporation Impeller for catheter pump
US9872947B2 (en) 2012-05-14 2018-01-23 Tc1 Llc Sheath system for catheter pump
US9358329B2 (en) 2012-07-03 2016-06-07 Thoratec Corporation Catheter pump
US9421311B2 (en) 2012-07-03 2016-08-23 Thoratec Corporation Motor assembly for catheter pump
EP4186557A1 (en) 2012-07-03 2023-05-31 Tc1 Llc Motor assembly for catheter pump
US11077294B2 (en) 2013-03-13 2021-08-03 Tc1 Llc Sheath assembly for catheter pump
EP3834876B1 (en) 2013-03-13 2022-09-14 Tc1 Llc Fluid handling system
US11033728B2 (en) 2013-03-13 2021-06-15 Tc1 Llc Fluid handling system
US9308302B2 (en) 2013-03-15 2016-04-12 Thoratec Corporation Catheter pump assembly including a stator
EP2968742B1 (en) 2013-03-15 2020-12-02 Tc1 Llc Catheter pump assembly including a stator
US10363349B2 (en) 2014-04-15 2019-07-30 Tc1 Llp Heart pump providing adjustable outflow
US10029037B2 (en) 2014-04-15 2018-07-24 Tc1 Llc Sensors for catheter pumps
US10583232B2 (en) 2014-04-15 2020-03-10 Tc1 Llc Catheter pump with off-set motor position
EP4417244A3 (en) 2014-04-15 2024-10-16 Tc1 Llc Catheter pump introducer system
EP3131599B1 (en) 2014-04-15 2019-02-20 Tc1 Llc Catheter pump with access ports
EP3583973A1 (en) 2014-08-18 2019-12-25 Tc1 Llc Guide features for percutaneous catheter pump
EP3247420B1 (en) 2015-01-22 2019-10-02 Tc1 Llc Reduced rotational mass motor assembly for catheter pump
WO2016118784A1 (en) 2015-01-22 2016-07-28 Thoratec Corporation Attachment mechanisms for motor of catheter pump
US9675739B2 (en) 2015-01-22 2017-06-13 Tc1 Llc Motor assembly with heat exchanger for catheter pump
US9907890B2 (en) 2015-04-16 2018-03-06 Tc1 Llc Catheter pump with positioning brace
EP3487550B1 (en) 2016-07-21 2022-09-28 Tc1 Llc Gas-filled chamber for catheter pump motor assembly
EP3804804A1 (en) 2016-07-21 2021-04-14 Tc1 Llc Fluid seals for catheter pump motor assembly
AU2017305392A1 (en) 2016-08-03 2019-02-21 Cymabay Therapeutics, Inc. Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
KR102419458B1 (ko) 2017-10-06 2022-07-12 길리애드 사이언시즈, 인코포레이티드 Acc 억제제를 포함하는 조합 요법
WO2021120134A1 (zh) 2019-12-19 2021-06-24 弈柯莱生物科技(上海)股份有限公司 一种氟乙酸脱卤酶突变体及其应用
CN116327749A (zh) * 2023-04-21 2023-06-27 重庆医科大学 Gw9662制备治疗非酒精性脂肪性肝炎药物的应用

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Also Published As

Publication number Publication date
PL1852433T3 (pl) 2012-05-31
KR20070072554A (ko) 2007-07-04
US8329913B2 (en) 2012-12-11
ATE534646T1 (de) 2011-12-15
TW200635922A (en) 2006-10-16
CA2585642C (en) 2013-04-02
KR101223820B1 (ko) 2013-01-17
WO2006046779A1 (ja) 2006-05-04
ES2378177T3 (es) 2012-04-09
AU2005297800B2 (en) 2011-02-03
EP1852433B1 (en) 2011-11-23
CY1112649T1 (el) 2016-02-10
CN101048402B (zh) 2011-11-09
JP3997491B2 (ja) 2007-10-24
AU2005297800A1 (en) 2006-05-04
US20100286210A1 (en) 2010-11-11
EP1852433A1 (en) 2007-11-07
EP1852433A4 (en) 2010-07-21
CA2585642A1 (en) 2006-05-04
SI1852433T1 (sl) 2012-06-29
CN101048402A (zh) 2007-10-03
PT1852433E (pt) 2012-02-08
JPWO2006046779A1 (ja) 2008-05-22
TWI359148B (2) 2012-03-01

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