DK1874953T3 - Fremgangsmåde til at bestemme phosphoryltransferaseaktivitet ved anvendelse af adenosin 5'-triphosphat(ATP)-gamma-S - Google Patents
Fremgangsmåde til at bestemme phosphoryltransferaseaktivitet ved anvendelse af adenosin 5'-triphosphat(ATP)-gamma-SInfo
- Publication number
- DK1874953T3 DK1874953T3 DK06750810T DK06750810T DK1874953T3 DK 1874953 T3 DK1874953 T3 DK 1874953T3 DK 06750810 T DK06750810 T DK 06750810T DK 06750810 T DK06750810 T DK 06750810T DK 1874953 T3 DK1874953 T3 DK 1874953T3
- Authority
- DK
- Denmark
- Prior art keywords
- triphosphate
- adenosine
- atp
- gamma
- determining
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- ZKHQWZAMYRWXGA-KQYNXXCUSA-N Adenosine triphosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-N 0.000 title 2
- ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 title 2
- 229960001456 adenosine triphosphate Drugs 0.000 title 2
- 102000004357 Transferases Human genes 0.000 title 1
- 108090000992 Transferases Proteins 0.000 title 1
- LFGREXWGYUGZLY-UHFFFAOYSA-N phosphoryl Chemical group [P]=O LFGREXWGYUGZLY-UHFFFAOYSA-N 0.000 title 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
- 229940043355 kinase inhibitor Drugs 0.000 abstract 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
- 238000007423 screening assay Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/008—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions for determining co-enzymes or co-factors, e.g. NAD, ATP
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/110,435 US7348159B2 (en) | 2005-04-20 | 2005-04-20 | Methods for determining phosphoryltransferase activity using adenosine 5'-triphosphate (ATP)-gamma-S |
| PCT/US2006/014860 WO2006113862A2 (en) | 2005-04-20 | 2006-04-20 | Methods for determining phosphoryltransferase activity using adenosine 5'-triphosphate (atp)-gamma-s |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1874953T3 true DK1874953T3 (da) | 2009-01-19 |
Family
ID=37115939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06750810T DK1874953T3 (da) | 2005-04-20 | 2006-04-20 | Fremgangsmåde til at bestemme phosphoryltransferaseaktivitet ved anvendelse af adenosin 5'-triphosphat(ATP)-gamma-S |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7348159B2 (da) |
| EP (1) | EP1874953B8 (da) |
| JP (1) | JP4875695B2 (da) |
| AT (1) | ATE412065T1 (da) |
| CA (1) | CA2605350A1 (da) |
| DE (1) | DE602006003324D1 (da) |
| DK (1) | DK1874953T3 (da) |
| ES (1) | ES2316076T3 (da) |
| WO (1) | WO2006113862A2 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006059881A1 (de) * | 2006-12-19 | 2008-07-03 | Sanofi-Aventis | Ein Hochdurchsatzassay zur Identifizierung von Kinaseinhibitoren und Kinaseaktivatoren basierend auf der Messung der ATP-Hydrolyse |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0030727D0 (en) | 2000-12-15 | 2001-01-31 | Lumitech Uk Ltd | Methods and kits for detecting kinase activity |
| JP4036655B2 (ja) * | 2001-02-14 | 2008-01-23 | シスメックス株式会社 | 細胞周期調節因子の活性の測定法と該測定法に使用される試薬 |
| EP1609854B1 (en) | 2001-02-14 | 2008-04-30 | Sysmex Corporation | Method for determining activity of cell cycle regulatory factor and method for diagnosing cancer using the same |
-
2005
- 2005-04-20 US US11/110,435 patent/US7348159B2/en not_active Expired - Lifetime
-
2006
- 2006-04-20 DE DE602006003324T patent/DE602006003324D1/de not_active Expired - Lifetime
- 2006-04-20 WO PCT/US2006/014860 patent/WO2006113862A2/en not_active Ceased
- 2006-04-20 ES ES06750810T patent/ES2316076T3/es not_active Expired - Lifetime
- 2006-04-20 DK DK06750810T patent/DK1874953T3/da active
- 2006-04-20 CA CA002605350A patent/CA2605350A1/en not_active Abandoned
- 2006-04-20 JP JP2008507864A patent/JP4875695B2/ja not_active Expired - Lifetime
- 2006-04-20 EP EP06750810A patent/EP1874953B8/en not_active Expired - Lifetime
- 2006-04-20 AT AT06750810T patent/ATE412065T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008536522A (ja) | 2008-09-11 |
| ATE412065T1 (de) | 2008-11-15 |
| ES2316076T3 (es) | 2009-04-01 |
| WO2006113862A2 (en) | 2006-10-26 |
| EP1874953B1 (en) | 2008-10-22 |
| EP1874953B8 (en) | 2008-12-24 |
| JP4875695B2 (ja) | 2012-02-15 |
| US20060240499A1 (en) | 2006-10-26 |
| EP1874953A2 (en) | 2008-01-09 |
| WO2006113862A3 (en) | 2007-03-08 |
| DE602006003324D1 (de) | 2008-12-04 |
| US7348159B2 (en) | 2008-03-25 |
| CA2605350A1 (en) | 2006-10-26 |
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