DK1877403T3 - Mono-lysinsalte af azolforbindelser - Google Patents

Mono-lysinsalte af azolforbindelser

Info

Publication number
DK1877403T3
DK1877403T3 DK06746245.7T DK06746245T DK1877403T3 DK 1877403 T3 DK1877403 T3 DK 1877403T3 DK 06746245 T DK06746245 T DK 06746245T DK 1877403 T3 DK1877403 T3 DK 1877403T3
Authority
DK
Denmark
Prior art keywords
mono
azole compounds
lysine salts
lysine
salts
Prior art date
Application number
DK06746245.7T
Other languages
English (en)
Inventor
Michael G Fakes
Yadagiri R Pendri
Susanne Kiau
Blisse Vakkalagadda
Qi Gao
Chung-Pin H Chen
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Application granted granted Critical
Publication of DK1877403T3 publication Critical patent/DK1877403T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK06746245.7T 2005-05-03 2006-05-01 Mono-lysinsalte af azolforbindelser DK1877403T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67693205P 2005-05-03 2005-05-03
PCT/JP2006/309435 WO2006118351A1 (en) 2005-05-03 2006-05-01 Mono-lysine salts of azole compounds

Publications (1)

Publication Number Publication Date
DK1877403T3 true DK1877403T3 (da) 2011-05-09

Family

ID=36910951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06746245.7T DK1877403T3 (da) 2005-05-03 2006-05-01 Mono-lysinsalte af azolforbindelser

Country Status (33)

Country Link
US (1) US20060264406A1 (da)
EP (1) EP1877403B1 (da)
JP (1) JP4015691B1 (da)
KR (1) KR100887044B1 (da)
CN (1) CN101213193B (da)
AR (1) AR053862A1 (da)
AT (1) ATE503753T1 (da)
AU (1) AU2006241694B2 (da)
BR (1) BRPI0610423B8 (da)
CA (1) CA2606185C (da)
CY (1) CY1111569T1 (da)
DE (1) DE602006020998D1 (da)
DK (1) DK1877403T3 (da)
EC (1) ECSP077812A (da)
ES (1) ES2361768T3 (da)
HR (1) HRP20110467T1 (da)
IL (1) IL187059A (da)
JO (1) JO2691B1 (da)
MX (1) MX2007013605A (da)
MY (1) MY138095A (da)
NO (1) NO20075541L (da)
NZ (1) NZ563092A (da)
PE (1) PE20071423A1 (da)
PL (1) PL1877403T3 (da)
PT (1) PT1877403E (da)
RS (1) RS51779B (da)
RU (1) RU2399625C2 (da)
SA (1) SA06270126B1 (da)
SI (1) SI1877403T1 (da)
TW (1) TWI363630B (da)
UY (1) UY29507A1 (da)
WO (1) WO2006118351A1 (da)
ZA (1) ZA200709127B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2432360T3 (es) * 2005-12-20 2013-12-03 Eisai R&D Management Co., Ltd. Procedimiento para la producción de profármaco de azol soluble en agua
JP5058150B2 (ja) 2006-02-22 2012-10-24 エーザイ・アール・アンド・ディー・マネジメント株式会社 安定化医薬組成物
CN105287403A (zh) * 2014-08-02 2016-02-03 陕西合成药业股份有限公司 一种泊沙康唑前体药物的冻干组合物及其制备方法和用途
CN106432338A (zh) * 2015-08-08 2017-02-22 陕西合成药业股份有限公司 泊沙康唑衍生物、合成和在长效制剂中的用途
WO2019106571A1 (en) 2017-11-28 2019-06-06 Roivant Sciences Gmbh Dosing regimens for the treatment of fungal infections
CN110938093B (zh) * 2018-09-21 2022-08-19 华创合成制药股份有限公司 一种泊沙康唑磷酸酯单胆碱盐及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9410142B (en) * 1993-12-21 1996-05-02 Schering Corp Tetrahydrofuran antifungals
KR100352147B1 (ko) * 1994-01-24 2002-11-11 얀센 파마슈티카 엔.브이. 수용성아졸항진균제
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
US5883097A (en) * 1998-04-16 1999-03-16 Schering Corporation Soluble azole antifungal salt
US6265584B1 (en) * 1998-05-22 2001-07-24 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
AU1915500A (en) * 1998-11-20 2000-06-13 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6235728B1 (en) * 1999-02-19 2001-05-22 Bristol-Myers Squibb Company Water-soluble prodrugs of azole compounds
US6362172B2 (en) * 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) * 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds

Also Published As

Publication number Publication date
NZ563092A (en) 2010-06-25
SI1877403T1 (sl) 2011-05-31
ES2361768T3 (es) 2011-06-22
TWI363630B (en) 2012-05-11
ECSP077812A (es) 2008-01-23
TW200722093A (en) 2007-06-16
UY29507A1 (es) 2006-11-30
AU2006241694A1 (en) 2006-11-09
MX2007013605A (es) 2008-01-24
KR100887044B1 (ko) 2009-03-04
RS51779B (sr) 2011-12-31
IL187059A (en) 2012-08-30
CN101213193A (zh) 2008-07-02
CY1111569T1 (el) 2015-10-07
AU2006241694B2 (en) 2011-10-20
CN101213193B (zh) 2011-02-02
KR20070088460A (ko) 2007-08-29
RU2007140788A (ru) 2009-06-10
ATE503753T1 (de) 2011-04-15
AR053862A1 (es) 2007-05-23
DE602006020998D1 (de) 2011-05-12
EP1877403B1 (en) 2011-03-30
MY138095A (en) 2009-04-30
IL187059A0 (en) 2008-02-09
BRPI0610423B8 (pt) 2021-05-25
SA06270126B1 (ar) 2009-09-02
JO2691B1 (en) 2013-03-03
EP1877403A1 (en) 2008-01-16
JP4015691B1 (ja) 2007-11-28
HK1117502A1 (en) 2009-01-16
RU2399625C2 (ru) 2010-09-20
BRPI0610423A2 (pt) 2010-06-22
ZA200709127B (en) 2008-07-30
US20060264406A1 (en) 2006-11-23
CA2606185C (en) 2012-08-28
JP2008544948A (ja) 2008-12-11
PL1877403T3 (pl) 2011-08-31
PT1877403E (pt) 2011-05-31
WO2006118351A1 (en) 2006-11-09
BRPI0610423B1 (pt) 2020-11-10
NO20075541L (no) 2007-11-28
CA2606185A1 (en) 2006-11-09
PE20071423A1 (es) 2006-12-17
HRP20110467T1 (hr) 2011-07-31

Similar Documents

Publication Publication Date Title
LTC2004635I2 (lt) Pakeistieji enaminokarbonilo junginiai
LTC2343304I2 (lt) Biocidiniai boronoftalido junginiai
DK1919907T3 (da) Heterocyklisk forbindelse
EP1873153A4 (en) HETEROCYCLIC CONNECTION
CY2013047I1 (el) Ενωσεις διαρυλυδαντοϊνης
DK2185567T3 (da) Substituerede bicyclolactam-forbindelser
EP2077267A4 (en) CONDENSED HETEROCYCLIC COMPOUND
ATE524477T1 (de) Aziridinylepothilonverbindungen
BRPI0811280A2 (pt) Compostos amino-heterocíclicos
EP2003132A4 (en) HETERO COMPOUND
BRPI0813500A2 (pt) Compostos antivirais
EP2123654A4 (en) pyrazolopyrimidine compound
EP2079466A4 (en) SUBSTITUTED INDOLE COMPOUNDS
EP1985620A4 (en) 10a-azalide compound
BRPI0811264A2 (pt) Compostos
EP2210876A4 (en) HETEROCYCLIC CONNECTION
BRPI0809996A2 (pt) Compostos
BRPI0814424A2 (pt) Compostos heterociclila
DK2371818T3 (da) Hydroxybenzoatsalte af metanikotinforbindelser
FI20065388L (fi) Betuliiniperäiset yhdisteet antimikrobisina aineina
DK1937650T3 (da) Heterocykliske forbindelser
DK1874766T3 (da) Krystallinsk form af en quinolinon-carboxamid-forbindelse
ATE443056T1 (de) Substituierte n-sulfonylaminophenylethyl-2- phenoxyacetamidverbindungen
ATE404546T1 (de) Substituierte n-sulfonylaminobenzyl-2- phenoxyacetamidverbindungen
EP2124549A4 (en) ANTIHYPERCHOLESTERINAMIC COMPOUNDS