DK1877559T3 - Mitochondrial mutationer og omarrangeringer som et diagnostisk værktøj for detektion af soleksponering, prostatacancer og andre cancertyper - Google Patents
Mitochondrial mutationer og omarrangeringer som et diagnostisk værktøj for detektion af soleksponering, prostatacancer og andre cancertyperInfo
- Publication number
- DK1877559T3 DK1877559T3 DK06741413.6T DK06741413T DK1877559T3 DK 1877559 T3 DK1877559 T3 DK 1877559T3 DK 06741413 T DK06741413 T DK 06741413T DK 1877559 T3 DK1877559 T3 DK 1877559T3
- Authority
- DK
- Denmark
- Prior art keywords
- detection
- cancers
- sun exposure
- prostate cancer
- rearrangements
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title abstract 3
- 230000036561 sun exposure Effects 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 206010060862 Prostate cancer Diseases 0.000 title abstract 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 title 1
- 230000002438 mitochondrial effect Effects 0.000 title 1
- 230000035772 mutation Effects 0.000 title 1
- 230000008707 rearrangement Effects 0.000 title 1
- 108020005196 Mitochondrial DNA Proteins 0.000 abstract 2
- 206010051403 Mitochondrial DNA deletion Diseases 0.000 abstract 1
- 208000000453 Skin Neoplasms Diseases 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 201000000849 skin cancer Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67201605P | 2005-04-18 | 2005-04-18 | |
| US72152205P | 2005-09-29 | 2005-09-29 | |
| US78987206P | 2006-04-07 | 2006-04-07 | |
| PCT/CA2006/000652 WO2006111029A1 (en) | 2005-04-18 | 2006-04-18 | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1877559T3 true DK1877559T3 (da) | 2011-02-07 |
Family
ID=37114687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06741413.6T DK1877559T3 (da) | 2005-04-18 | 2006-04-18 | Mitochondrial mutationer og omarrangeringer som et diagnostisk værktøj for detektion af soleksponering, prostatacancer og andre cancertyper |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US8008008B2 (da) |
| EP (2) | EP2339032B1 (da) |
| JP (2) | JP5537804B2 (da) |
| KR (1) | KR101363032B1 (da) |
| CN (2) | CN103789405B (da) |
| AT (1) | ATE484589T1 (da) |
| AU (1) | AU2006238390B2 (da) |
| CA (2) | CA2792443A1 (da) |
| DE (1) | DE602006017534D1 (da) |
| DK (1) | DK1877559T3 (da) |
| ES (1) | ES2354452T3 (da) |
| NZ (2) | NZ562928A (da) |
| PT (1) | PT1877559E (da) |
| SG (1) | SG2014011837A (da) |
| WO (1) | WO2006111029A1 (da) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130022979A1 (en) * | 2005-04-18 | 2013-01-24 | Genesis Genomics Inc. | 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER |
| NZ562928A (en) * | 2005-04-18 | 2011-01-28 | Mitomics Inc | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
| CN100526453C (zh) * | 2005-05-20 | 2009-08-12 | 麦克奥迪实业集团有限公司 | 激光显微切割后细胞收集方法 |
| AU2005333512A1 (en) * | 2005-06-16 | 2006-12-28 | Biotools Biotechnological & Medical Laboratories, S.A. | Nucleic acid detection method involving the direct generation of a measurable signal |
| US20080254530A1 (en) * | 2007-02-27 | 2008-10-16 | Gettysburg College | Isolation and characterization of a single mitochondrion |
| EP2203570B1 (en) * | 2007-09-26 | 2014-04-23 | Mitomics Inc. | 3.4 kb mitochondrial dna deletion for use in the detection of cancer |
| WO2009046514A1 (en) * | 2007-10-11 | 2009-04-16 | Genesis Genomics Inc. | Methods for non-invasive collection of skin cells for dna analysis |
| CN101896622B (zh) * | 2007-10-11 | 2015-07-22 | 米托米克斯公司 | 测定皮肤样本中mc1r变体和线粒体标记物的方法 |
| CA2704361C (en) * | 2007-11-09 | 2023-04-04 | Genesis Genomics Inc. | Mitochondrial dna deletion between about residues 12317-16254 for use in the detection of cancer |
| EP2274426B1 (en) * | 2008-03-28 | 2016-11-16 | MDNA Life Sciences Inc. | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
| BRPI0917711A2 (pt) * | 2008-08-28 | 2017-06-20 | Astute Medical Inc | método para avaliar o estado renal em um paciente, e, uso de um ou mais marcadores de lesão renal |
| WO2010025434A1 (en) * | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN104076152B (zh) * | 2008-10-21 | 2017-04-19 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| CN106370857A (zh) | 2008-10-21 | 2017-02-01 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| JP5752600B2 (ja) | 2008-11-10 | 2015-07-22 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後のための方法 |
| CN103439510B (zh) * | 2008-11-22 | 2016-09-14 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| AU2010234238B2 (en) * | 2009-03-27 | 2016-07-28 | Mdna Life Sciences Inc. | Aberrant mitochondrial DNA, associated fusion transcripts and translation products and hybridization probes therefor |
| EP2425240A4 (en) | 2009-04-30 | 2012-12-12 | Good Start Genetics Inc | METHOD AND COMPOSITION FOR EVALUATING GENETIC MARKERS |
| US12129514B2 (en) | 2009-04-30 | 2024-10-29 | Molecular Loop Biosolutions, Llc | Methods and compositions for evaluating genetic markers |
| US8871459B2 (en) | 2009-08-07 | 2014-10-28 | Astute Medical, Inc. | Method for evaluating renal status by determining beta-2-glycoprotein 1 |
| NZ599773A (en) | 2009-11-07 | 2014-09-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP2011115098A (ja) * | 2009-12-04 | 2011-06-16 | Nippon Menaade Keshohin Kk | 加齢による皮膚明度の低下を予測する皮膚評価方法 |
| CN102725636B (zh) | 2009-12-20 | 2015-04-01 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| CA2788826C (en) | 2010-02-05 | 2023-09-26 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011162819A1 (en) | 2010-06-23 | 2011-12-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2539712A4 (en) | 2010-02-26 | 2013-09-18 | Astute Medical Inc | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE |
| EP3305902A1 (en) * | 2010-03-01 | 2018-04-11 | MDNA Life Sciences Inc. | Uv associated mtdna fusion transcripts and methods and uses thereof |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US9163281B2 (en) | 2010-12-23 | 2015-10-20 | Good Start Genetics, Inc. | Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction |
| AU2012242847B2 (en) | 2011-04-15 | 2017-01-19 | The Johns Hopkins University | Safe sequencing system |
| EP2768983A4 (en) | 2011-10-17 | 2015-06-03 | Good Start Genetics Inc | METHODS OF IDENTIFYING MUTATIONS ASSOCIATED WITH DISEASES |
| WO2013086359A1 (en) | 2011-12-08 | 2013-06-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US8209130B1 (en) | 2012-04-04 | 2012-06-26 | Good Start Genetics, Inc. | Sequence assembly |
| US8812422B2 (en) | 2012-04-09 | 2014-08-19 | Good Start Genetics, Inc. | Variant database |
| US10227635B2 (en) | 2012-04-16 | 2019-03-12 | Molecular Loop Biosolutions, Llc | Capture reactions |
| EP2875173B1 (en) * | 2012-07-17 | 2017-06-28 | Counsyl, Inc. | System and methods for detecting genetic variation |
| ES2701742T3 (es) | 2012-10-29 | 2019-02-25 | Univ Johns Hopkins | Prueba de Papanicolaou para cánceres de ovario y de endometrio |
| WO2014071178A1 (en) * | 2012-11-05 | 2014-05-08 | Icahn School Of Medicine At Mount Sinai | Method of isolating pure mitochondrial dna |
| ES2482866B1 (es) * | 2012-11-22 | 2015-05-12 | Consejo Superior De Investigaciones Científicas (Csic) | Método de diagnóstico y/o pronóstico de enfermedades neurodegenerativas. |
| JP6681195B2 (ja) | 2013-01-17 | 2020-04-15 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| US8778609B1 (en) | 2013-03-14 | 2014-07-15 | Good Start Genetics, Inc. | Methods for analyzing nucleic acids |
| EP3005200A2 (en) | 2013-06-03 | 2016-04-13 | Good Start Genetics, Inc. | Methods and systems for storing sequence read data |
| US10851414B2 (en) | 2013-10-18 | 2020-12-01 | Good Start Genetics, Inc. | Methods for determining carrier status |
| WO2015057565A1 (en) | 2013-10-18 | 2015-04-23 | Good Start Genetics, Inc. | Methods for assessing a genomic region of a subject |
| US9745611B2 (en) * | 2014-05-06 | 2017-08-29 | Genewiz Inc. | Methods and kits for identifying microorganisms in a sample |
| WO2015175530A1 (en) | 2014-05-12 | 2015-11-19 | Gore Athurva | Methods for detecting aneuploidy |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| CN104062294A (zh) * | 2014-07-11 | 2014-09-24 | 青岛千士医疗科技有限公司 | 一种支气管/肺上皮细胞线粒体损伤的检测方法 |
| WO2016025818A1 (en) | 2014-08-15 | 2016-02-18 | Good Start Genetics, Inc. | Systems and methods for genetic analysis |
| US11408024B2 (en) | 2014-09-10 | 2022-08-09 | Molecular Loop Biosciences, Inc. | Methods for selectively suppressing non-target sequences |
| JP2017536087A (ja) | 2014-09-24 | 2017-12-07 | グッド スタート ジェネティクス, インコーポレイテッド | 遺伝子アッセイのロバストネスを増大させるためのプロセス制御 |
| KR20210013299A (ko) | 2014-10-17 | 2021-02-03 | 코디악 사이언시스 인코포레이티드 | 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트 |
| US10066259B2 (en) | 2015-01-06 | 2018-09-04 | Good Start Genetics, Inc. | Screening for structural variants |
| EP3091083B1 (en) | 2015-05-07 | 2017-11-08 | Latvian Biomedical Research and Study Centre | A kit for detecting mutation or polymorphism in the human mitochondrial dna |
| KR20170007181A (ko) | 2015-07-10 | 2017-01-18 | 3스캔 인크. | 조직학적 염색제의 공간 다중화 |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| CN109844526A (zh) | 2016-06-06 | 2019-06-04 | 机敏医药股份有限公司 | 使用胰岛素样生长因子结合蛋白7和金属蛋白酶2的组织抑制剂管理急性肾损伤 |
| CN120400338A (zh) | 2017-08-07 | 2025-08-01 | 约翰斯霍普金斯大学 | 用于评估和治疗癌症的方法和材料 |
| CN108827887B (zh) * | 2018-03-19 | 2021-05-18 | 陕西学前师范学院 | 一种商陆基因组大小估计方法及基因组大小测量系统 |
| EP3578671A1 (en) * | 2018-06-05 | 2019-12-11 | Universitat Autònoma De Barcelona | Method for evaluating risk of cardiovascular disease |
| CN109360656B (zh) * | 2018-08-20 | 2021-11-02 | 安徽大学 | 一种基于多目标演化算法的癌症检测方法 |
| US20220220472A1 (en) * | 2019-05-06 | 2022-07-14 | The Regents Of The University Of Michigan | Targeted therapy |
| CN110378881B (zh) * | 2019-07-05 | 2020-03-24 | 北京航空航天大学 | 一种基于深度学习的肿瘤定位系统 |
| CN110358856B (zh) * | 2019-07-23 | 2023-04-07 | 四川省农业科学院生物技术核技术研究所 | 侧耳属线粒体nad4L基因的扩增引物及其在鉴定侧耳属物种中的应用 |
| CN113025633B (zh) * | 2019-12-09 | 2024-08-27 | 武汉纽福斯生物科技有限公司 | 编码人nadh脱氢酶亚单位1蛋白的核酸及其应用 |
| IL295297A (en) | 2020-02-14 | 2022-10-01 | Univ Johns Hopkins | Methods and materials for assessing nucleic acids |
| US20230235400A1 (en) * | 2020-06-04 | 2023-07-27 | The General Hospital Corporation | Methods of detecting mitochondrial diseases |
| CN117070511B (zh) * | 2023-08-16 | 2024-02-02 | 广州卿泽生物科技有限公司 | 一种用于扩增人类线粒体全基因组的引物组及其应用 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2356536A (en) * | 1939-07-18 | 1944-08-22 | Rzymkowski Johannes | Developing process |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US6027883A (en) | 1994-03-30 | 2000-02-22 | Mitokor | Optimal procedure for isolation of mutant mitochondrial alleles |
| US5565323A (en) | 1994-03-30 | 1996-10-15 | Mitokor | Cytochrome oxidase mutations aiding diagnosis of sporadic alzheimer's disease |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| EP0812922A3 (en) | 1996-05-16 | 2002-08-21 | Affymetrix, Inc. (a California Corporation) | Polymorphisms in human mitochondrial nucleic acid |
| JP3251219B2 (ja) | 1997-10-13 | 2002-01-28 | 雅嗣 田中 | ヒトミトコンドリアdnaを用いた遺伝子検出方法 |
| US6605433B1 (en) | 1998-08-20 | 2003-08-12 | The Johns Hopkins University | Mitochondrial dosimeter |
| ATE259425T1 (de) | 1998-08-20 | 2004-02-15 | Univ Johns Hopkins Med | Mitochondriale, als tumormarker geeignete mutationen, die nur ein basenpaar betreffen |
| US20020068277A1 (en) * | 1998-11-20 | 2002-06-06 | Simpson Andrew John George | Method for determining nucleotide sequences using arbitrary primers and low stringency |
| JP2003521879A (ja) | 1999-04-20 | 2003-07-22 | マイトコー | アルツハイマー病とともに分離するミトコンドリア遺伝子における一塩基多型 |
| SE0003286D0 (sv) | 2000-09-15 | 2000-09-15 | Ulf Gyllensten | Method and kit for human identification |
| US20030092019A1 (en) | 2001-01-09 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia |
| EP1397508A2 (en) * | 2001-06-11 | 2004-03-17 | 1304854 Ontario Ltd | Complete mitochondrial genome sequences as a diagnostic tool for the health sciences |
| US20030162174A1 (en) | 2001-06-11 | 2003-08-28 | Sutherland John W. | Detecting nucleic acid deletion sequences |
| US20050026167A1 (en) | 2001-06-11 | 2005-02-03 | Mark Birch-Machin | Complete mitochondrial genome sequences as a diagnostic tool for the health sciences |
| US20040191769A1 (en) * | 2001-07-24 | 2004-09-30 | Transgenomic, Inc. | Methods, compositions, and kits for mutation detection in mitochondrial DNA |
| CA2356536A1 (en) * | 2001-08-30 | 2003-02-28 | Emory University | Mitochondrial dna sequence alleles |
| SE0200817D0 (sv) * | 2002-03-15 | 2002-03-15 | Ulf Gyllensten | Method and kit for detection of mutations in mitochondrial DNA |
| US20050244851A1 (en) * | 2004-01-13 | 2005-11-03 | Affymetrix, Inc. | Methods of analysis of alternative splicing in human |
| NZ562928A (en) * | 2005-04-18 | 2011-01-28 | Mitomics Inc | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
-
2006
- 2006-04-18 NZ NZ562928A patent/NZ562928A/en not_active IP Right Cessation
- 2006-04-18 NZ NZ587665A patent/NZ587665A/en not_active IP Right Cessation
- 2006-04-18 DE DE602006017534T patent/DE602006017534D1/de not_active Expired - Lifetime
- 2006-04-18 SG SG2014011837A patent/SG2014011837A/en unknown
- 2006-04-18 JP JP2008505707A patent/JP5537804B2/ja not_active Expired - Fee Related
- 2006-04-18 PT PT06741413T patent/PT1877559E/pt unknown
- 2006-04-18 CA CA2792443A patent/CA2792443A1/en not_active Abandoned
- 2006-04-18 EP EP10013553.2A patent/EP2339032B1/en not_active Expired - Lifetime
- 2006-04-18 AU AU2006238390A patent/AU2006238390B2/en not_active Ceased
- 2006-04-18 KR KR1020077026442A patent/KR101363032B1/ko not_active Expired - Fee Related
- 2006-04-18 CN CN201310399746.XA patent/CN103789405B/zh not_active Expired - Fee Related
- 2006-04-18 AT AT06741413T patent/ATE484589T1/de active
- 2006-04-18 EP EP06741413A patent/EP1877559B1/en not_active Expired - Lifetime
- 2006-04-18 CN CN2006800219031A patent/CN101248180B/zh not_active Expired - Fee Related
- 2006-04-18 CA CA2606156A patent/CA2606156C/en not_active Expired - Lifetime
- 2006-04-18 ES ES06741413T patent/ES2354452T3/es not_active Expired - Lifetime
- 2006-04-18 DK DK06741413.6T patent/DK1877559T3/da active
- 2006-04-18 WO PCT/CA2006/000652 patent/WO2006111029A1/en not_active Ceased
-
2007
- 2007-10-18 US US11/975,390 patent/US8008008B2/en active Active
-
2011
- 2011-08-30 US US13/221,618 patent/US20120058483A1/en not_active Abandoned
-
2012
- 2012-04-26 JP JP2012101409A patent/JP6134890B2/ja not_active Expired - Fee Related
-
2014
- 2014-08-27 US US14/470,627 patent/US9745632B2/en not_active Expired - Fee Related
-
2017
- 2017-08-29 US US15/690,147 patent/US10907213B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG2014011837A (en) | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers | |
| LTPA2017011I1 (lt) | Antikūnas prieš PDGFR-alfa, skirtas naudoti auglių gydymui | |
| CY1122210T1 (el) | Ανθρωπινα αντισωματα anti-sod1 | |
| DE602004009967D1 (de) | Gsm-strahlungsempfindlichkeits-messtechnik | |
| ITTO20020808A1 (it) | Dispositivo integrato di analisi del dna. | |
| DK1492440T3 (da) | Fremgangsmåde til opnåelse af en diagnose og prognose for maligne sygdomme | |
| BRPI0809137A2 (pt) | métodos de diagnosticar, câncer endometrial e pré-câncer classificar e tratar | |
| DK1721992T3 (da) | Fremgangsmåder og nukleinsyrer til analyser af cellulære proliferative sygdomme | |
| MX2007004342A (es) | Moleculas cop1 y uso de las mismas. | |
| DE602006016378D1 (de) | Extrem-UV-Strahlungsquelle | |
| CL2004000934A1 (es) | Conjunto de elementos que comprende cebadores para reconocer la linea de maiz tc1507, metodo para detectar la linea de maiz tc1507 o la progenie del mismo en una muestra biologica. | |
| DE112005001544T5 (de) | Innen-einsetzbares Rohr-Untersuchungswerkzeug | |
| ATE553134T1 (de) | Strahlungsbeugungsfarbmittel | |
| NO20053429D0 (no) | Teknikk for ikke-koherent integrasjon av mal med tvetydige hastigheter. | |
| WO2007008759A3 (en) | Methods for detecting and confirming minimal disease in a cancer patient | |
| EP2574193A4 (en) | PROOF OF THIOL | |
| DE602005004592D1 (de) | Lithografische Vorrichtung, Beleuchtungssystem und Debrisauffangsystem | |
| CY1115439T1 (el) | Μεθοδοι και νουκλεϊκα οξεα για αναλυσεις διαταραχων του κυτταρικου πολλαπλασιασμου | |
| DE10322712A8 (de) | Strahlungsquellenpositions-Erfassungsverfahren, Strahlungsquellenpositions-Erfassungssystem, und Strahlungsquellenpositions-Erfassungssonde | |
| BRPI0718850A2 (pt) | Métodos de tratar, diagnosticar ou detectar câncer | |
| EP2217387A4 (en) | METALALKOXIDES, METHOD FOR PRODUCING METALALKOXIDES, CORRESPONDING METHODS AND THEIR USE | |
| SG165370A1 (en) | Method for the diagnosis of colorectal cancer and ovarian cancer by the measurement of vitamin e-related metabolites | |
| NO20084066L (no) | Method and apparatus for performing spectroscopy downhole within a wellbore | |
| CY1123191T1 (el) | Δοκιμασιες υποδοχεων στεροειδων για ανιχνευση κυτταρων ογκου | |
| DE602004018155D1 (de) | Einen grössenausschlussschritt verwendendes verbessertes bisulfit-verfahren |