DK1910376T3 - Nye camptothecinanaloge forbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende nævnte forbindelser - Google Patents
Nye camptothecinanaloge forbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende nævnte forbindelserInfo
- Publication number
- DK1910376T3 DK1910376T3 DK06794287T DK06794287T DK1910376T3 DK 1910376 T3 DK1910376 T3 DK 1910376T3 DK 06794287 T DK06794287 T DK 06794287T DK 06794287 T DK06794287 T DK 06794287T DK 1910376 T3 DK1910376 T3 DK 1910376T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- preparation
- methods
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- KLWPJMFMVPTNCC-UHFFFAOYSA-N Camptothecin Natural products CCC1(O)C(=O)OCC2=C1C=C3C4Nc5ccccc5C=C4CN3C2=O KLWPJMFMVPTNCC-UHFFFAOYSA-N 0.000 title 1
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical compound C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
- 229940127093 camptothecin Drugs 0.000 title 1
- VSJKWCGYPAHWDS-UHFFFAOYSA-N dl-camptothecin Natural products C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)C5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0508365A FR2889528B1 (fr) | 2005-08-05 | 2005-08-05 | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR2006/001900 WO2007017584A1 (fr) | 2005-08-05 | 2006-08-04 | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1910376T3 true DK1910376T3 (da) | 2010-01-11 |
Family
ID=36216982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06794287T DK1910376T3 (da) | 2005-08-05 | 2006-08-04 | Nye camptothecinanaloge forbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende nævnte forbindelser |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20100168150A1 (pl) |
| EP (1) | EP1910376B1 (pl) |
| JP (1) | JP2009505963A (pl) |
| KR (1) | KR20080032006A (pl) |
| CN (1) | CN101233140B (pl) |
| AR (1) | AR055596A1 (pl) |
| AT (1) | ATE444297T1 (pl) |
| AU (1) | AU2006277862A1 (pl) |
| BR (1) | BRPI0614522A2 (pl) |
| CA (1) | CA2617951A1 (pl) |
| CY (1) | CY1110545T1 (pl) |
| DE (1) | DE602006009524D1 (pl) |
| DK (1) | DK1910376T3 (pl) |
| EA (1) | EA014754B1 (pl) |
| ES (1) | ES2334263T3 (pl) |
| FR (1) | FR2889528B1 (pl) |
| GE (1) | GEP20115229B (pl) |
| HR (1) | HRP20090651T1 (pl) |
| MA (1) | MA29648B1 (pl) |
| MX (1) | MX2008001559A (pl) |
| NO (1) | NO20081157L (pl) |
| NZ (1) | NZ565397A (pl) |
| PL (1) | PL1910376T3 (pl) |
| PT (1) | PT1910376E (pl) |
| RS (1) | RS51061B (pl) |
| SI (1) | SI1910376T1 (pl) |
| UA (1) | UA95254C2 (pl) |
| WO (1) | WO2007017584A1 (pl) |
| ZA (1) | ZA200801992B (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2889527A1 (fr) * | 2005-08-05 | 2007-02-09 | Servier Lab | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6699876B2 (en) * | 1999-11-18 | 2004-03-02 | Les Laboratoires Servier | Camptothecin analogue compounds |
| FR2801309B1 (fr) * | 1999-11-18 | 2002-01-04 | Adir | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6403604B1 (en) * | 2001-03-01 | 2002-06-11 | California Pacific Medical Center | Nitrogen-based camptothecin derivatives |
| WO2003101998A1 (en) * | 2002-06-03 | 2003-12-11 | California Pacific Medical Center | Nitrogen-based homo-camptothecin derivatives |
| CN100443486C (zh) * | 2002-09-11 | 2008-12-17 | 中国医学科学院药物研究所 | 7-酯化和7,20-双酯化的喜树碱衍生物及其制法和其药物组合物与用途 |
| FR2889527A1 (fr) * | 2005-08-05 | 2007-02-09 | Servier Lab | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2005
- 2005-08-05 FR FR0508365A patent/FR2889528B1/fr not_active Expired - Fee Related
-
2006
- 2006-08-04 GE GEAP200610545A patent/GEP20115229B/en unknown
- 2006-08-04 KR KR1020087005341A patent/KR20080032006A/ko not_active Ceased
- 2006-08-04 NZ NZ565397A patent/NZ565397A/en unknown
- 2006-08-04 EP EP06794287A patent/EP1910376B1/fr active Active
- 2006-08-04 AU AU2006277862A patent/AU2006277862A1/en not_active Abandoned
- 2006-08-04 CA CA002617951A patent/CA2617951A1/fr not_active Abandoned
- 2006-08-04 ZA ZA200801992A patent/ZA200801992B/xx unknown
- 2006-08-04 AR ARP060103406A patent/AR055596A1/es unknown
- 2006-08-04 BR BRPI0614522-1A patent/BRPI0614522A2/pt not_active IP Right Cessation
- 2006-08-04 EA EA200800392A patent/EA014754B1/ru not_active IP Right Cessation
- 2006-08-04 RS RSP-2009/0501A patent/RS51061B/sr unknown
- 2006-08-04 SI SI200630464T patent/SI1910376T1/sl unknown
- 2006-08-04 DE DE602006009524T patent/DE602006009524D1/de active Active
- 2006-08-04 CN CN2006800280345A patent/CN101233140B/zh not_active Expired - Fee Related
- 2006-08-04 HR HR20090651T patent/HRP20090651T1/hr unknown
- 2006-08-04 US US11/990,104 patent/US20100168150A1/en not_active Abandoned
- 2006-08-04 WO PCT/FR2006/001900 patent/WO2007017584A1/fr not_active Ceased
- 2006-08-04 DK DK06794287T patent/DK1910376T3/da active
- 2006-08-04 UA UAA200802669A patent/UA95254C2/ru unknown
- 2006-08-04 AT AT06794287T patent/ATE444297T1/de active
- 2006-08-04 PT PT06794287T patent/PT1910376E/pt unknown
- 2006-08-04 ES ES06794287T patent/ES2334263T3/es active Active
- 2006-08-04 MX MX2008001559A patent/MX2008001559A/es active IP Right Grant
- 2006-08-04 JP JP2008524548A patent/JP2009505963A/ja active Pending
- 2006-08-04 PL PL06794287T patent/PL1910376T3/pl unknown
-
2008
- 2008-01-28 MA MA30600A patent/MA29648B1/fr unknown
- 2008-03-05 NO NO20081157A patent/NO20081157L/no not_active Application Discontinuation
-
2009
- 2009-11-09 CY CY20091101160T patent/CY1110545T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20090651T1 (hr) | 2010-01-31 |
| FR2889528B1 (fr) | 2007-09-07 |
| NO20081157L (no) | 2008-03-05 |
| NZ565397A (en) | 2011-06-30 |
| RS51061B (sr) | 2010-10-31 |
| CN101233140A (zh) | 2008-07-30 |
| ATE444297T1 (de) | 2009-10-15 |
| FR2889528A1 (fr) | 2007-02-09 |
| DE602006009524D1 (de) | 2009-11-12 |
| EP1910376B1 (fr) | 2009-09-30 |
| CA2617951A1 (fr) | 2007-02-15 |
| PT1910376E (pt) | 2009-11-05 |
| PL1910376T3 (pl) | 2009-12-31 |
| EA014754B1 (ru) | 2011-02-28 |
| GEP20115229B (en) | 2011-06-10 |
| KR20080032006A (ko) | 2008-04-11 |
| WO2007017584A1 (fr) | 2007-02-15 |
| CN101233140B (zh) | 2011-05-25 |
| UA95254C2 (ru) | 2011-07-25 |
| US20100168150A1 (en) | 2010-07-01 |
| AR055596A1 (es) | 2007-08-29 |
| EP1910376A1 (fr) | 2008-04-16 |
| CY1110545T1 (el) | 2015-04-29 |
| SI1910376T1 (sl) | 2010-01-29 |
| MA29648B1 (fr) | 2008-07-01 |
| AU2006277862A1 (en) | 2007-02-15 |
| JP2009505963A (ja) | 2009-02-12 |
| HK1123048A1 (en) | 2009-06-05 |
| ES2334263T3 (es) | 2010-03-08 |
| ZA200801992B (en) | 2009-07-29 |
| MX2008001559A (es) | 2008-02-15 |
| EA200800392A1 (ru) | 2008-08-29 |
| BRPI0614522A2 (pt) | 2019-04-24 |
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