DK1910400T3 - Forbedret krystallinsk form af forbindelsen A-348441 - Google Patents

Forbedret krystallinsk form af forbindelsen A-348441

Info

Publication number: DK1910400T3
Authority: DK; Denmark
Prior art keywords: crystalline form; compound; improved crystalline; ynylestra; cholan
Prior art date: 2005-07-12

Application number

DK06762551.7T

Other languages

English (en)

Inventor

Russell Drew Cink

Daozhong Zou

Marvin Robert Leanna

Pascal H Toma

Michelle Andree Long

Original Assignee

Karobio Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-07-12

Filing date

2006-07-12

Publication date

2011-02-28

2006-07-12 Application filed by Karobio Ab filed Critical Karobio Ab

2011-02-28 Application granted granted Critical

2011-02-28 Publication of DK1910400T3 publication Critical patent/DK1910400T3/da

Links

150000001875 compounds Chemical class 0.000 title 1
238000002441 X-ray diffraction Methods 0.000 abstract 1
239000002178 crystalline material Substances 0.000 abstract 1
125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
239000003862 glucocorticoid Substances 0.000 abstract 1
230000002440 hepatic effect Effects 0.000 abstract 1
RPKLZQLYODPWTM-UHFFFAOYSA-N methyl 15-acetoxy(10),13E-ent-halimadien-18-oate Natural products C1CC2CCCCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RPKLZQLYODPWTM-UHFFFAOYSA-N 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Polyesters Or Polycarbonates (AREA)
Liquid Crystal Substances (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Processes Of Treating Macromolecular Substances (AREA)

DK06762551.7T 2005-07-12 2006-07-12 Forbedret krystallinsk form af forbindelsen A-348441 DK1910400T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0514302.9A GB0514302D0 (en)	2005-07-12	2005-07-12	Improved crystalline material
PCT/EP2006/006811 WO2007006561A2 (en)	2005-07-12	2006-07-12	Improved crystalline form of the compound a-348441

Publications (1)

Publication Number	Publication Date
DK1910400T3 true DK1910400T3 (da)	2011-02-28

Family

ID=34897118

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK06762551.7T DK1910400T3 (da)	2005-07-12	2006-07-12	Forbedret krystallinsk form af forbindelsen A-348441

Country Status (16)

Country	Link
US (1)	US8124129B2 (da)
EP (1)	EP1910400B1 (da)
JP (1)	JP2009501175A (da)
CN (1)	CN101218246B (da)
AT (1)	ATE488525T1 (da)
AU (1)	AU2006268842B2 (da)
BR (1)	BRPI0612986A2 (da)
CA (1)	CA2614048A1 (da)
DE (1)	DE602006018318D1 (da)
DK (1)	DK1910400T3 (da)
ES (1)	ES2356255T3 (da)
GB (1)	GB0514302D0 (da)
IL (1)	IL188551A0 (da)
NO (1)	NO20080094L (da)
WO (1)	WO2007006561A2 (da)
ZA (1)	ZA200800278B (da)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN100348609C (zh) *	2002-06-19	2007-11-14	卡罗生物股份公司	治疗代谢紊乱的糖皮质激素受体配基

2005
- 2005-07-12 GB GBGB0514302.9A patent/GB0514302D0/en not_active Ceased
2006
- 2006-07-12 CA CA002614048A patent/CA2614048A1/en not_active Abandoned
- 2006-07-12 US US11/988,330 patent/US8124129B2/en not_active Expired - Fee Related
- 2006-07-12 BR BRPI0612986-2A patent/BRPI0612986A2/pt not_active IP Right Cessation
- 2006-07-12 WO PCT/EP2006/006811 patent/WO2007006561A2/en not_active Ceased
- 2006-07-12 AU AU2006268842A patent/AU2006268842B2/en not_active Expired - Fee Related
- 2006-07-12 DK DK06762551.7T patent/DK1910400T3/da active
- 2006-07-12 EP EP06762551A patent/EP1910400B1/en not_active Not-in-force
- 2006-07-12 JP JP2008520790A patent/JP2009501175A/ja active Pending
- 2006-07-12 DE DE602006018318T patent/DE602006018318D1/de active Active
- 2006-07-12 CN CN200680025210XA patent/CN101218246B/zh not_active Expired - Fee Related
- 2006-07-12 AT AT06762551T patent/ATE488525T1/de not_active IP Right Cessation
- 2006-07-12 ES ES06762551T patent/ES2356255T3/es active Active
2008
- 2008-01-02 IL IL188551A patent/IL188551A0/en unknown
- 2008-01-07 NO NO20080094A patent/NO20080094L/no not_active Application Discontinuation
- 2008-01-09 ZA ZA200800278A patent/ZA200800278B/xx unknown

Also Published As

Publication number	Publication date
ZA200800278B (en)	2009-03-25
WO2007006561A3 (en)	2007-04-12
JP2009501175A (ja)	2009-01-15
CN101218246B (zh)	2011-06-15
IL188551A0 (en)	2008-04-13
US20090176754A1 (en)	2009-07-09
WO2007006561A2 (en)	2007-01-18
ATE488525T1 (de)	2010-12-15
CA2614048A1 (en)	2007-01-18
AU2006268842B2 (en)	2012-02-23
CN101218246A (zh)	2008-07-09
EP1910400A2 (en)	2008-04-16
DE602006018318D1 (de)	2010-12-30
US8124129B2 (en)	2012-02-28
EP1910400B1 (en)	2010-11-17
BRPI0612986A2 (pt)	2010-12-14
ES2356255T3 (es)	2011-04-06
AU2006268842A1 (en)	2007-01-18
NO20080094L (no)	2008-03-26
GB0514302D0 (en)	2005-08-17

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