DK1919450T3 - Antihistamin- og corticosteroidholdig liposomsammensætning og dens anvendelse til fremstilling af et lægemiddel til behandling af rhinitis og beslægtede lidelser - Google Patents
Antihistamin- og corticosteroidholdig liposomsammensætning og dens anvendelse til fremstilling af et lægemiddel til behandling af rhinitis og beslægtede lidelserInfo
- Publication number
- DK1919450T3 DK1919450T3 DK06779244.0T DK06779244T DK1919450T3 DK 1919450 T3 DK1919450 T3 DK 1919450T3 DK 06779244 T DK06779244 T DK 06779244T DK 1919450 T3 DK1919450 T3 DK 1919450T3
- Authority
- DK
- Denmark
- Prior art keywords
- antihistamine
- corticosteroid
- rhinitis
- drug
- manufacture
- Prior art date
Links
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
- 230000001387 anti-histamine Effects 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
- 239000003246 corticosteroid Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000002502 liposome Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 206010039083 rhinitis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71282205P | 2005-09-01 | 2005-09-01 | |
| PCT/GB2006/003222 WO2007026151A1 (en) | 2005-09-01 | 2006-08-31 | Antihistamine- and corticosteroid- containing liposome composition and its use for the manufacture of a medicament for treating rhinitis and related disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1919450T3 true DK1919450T3 (da) | 2014-09-15 |
Family
ID=35219424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06779244.0T DK1919450T3 (da) | 2005-09-01 | 2006-08-31 | Antihistamin- og corticosteroidholdig liposomsammensætning og dens anvendelse til fremstilling af et lægemiddel til behandling af rhinitis og beslægtede lidelser |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20090324699A1 (da) |
| EP (1) | EP1919450B1 (da) |
| JP (1) | JP5393151B2 (da) |
| CN (1) | CN101257891A (da) |
| BR (1) | BRPI0615032A2 (da) |
| CA (1) | CA2616515C (da) |
| DK (1) | DK1919450T3 (da) |
| ES (1) | ES2498795T3 (da) |
| PL (1) | PL1919450T3 (da) |
| PT (1) | PT1919450E (da) |
| RU (1) | RU2444351C2 (da) |
| SI (1) | SI1919450T1 (da) |
| WO (1) | WO2007026151A1 (da) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8207188B2 (en) * | 2006-04-07 | 2012-06-26 | Michalis Nicolaou | Treatment of diseases modulated by a H4 receptor agonist |
| US7378082B1 (en) | 2007-11-05 | 2008-05-27 | Inspire Pharmaceuticals, Inc. | Method for treating allergic rhinitis without adverse effects |
| GB0719518D0 (en) * | 2007-10-05 | 2007-11-14 | Therapeutics Ltd E | Therapy |
| EP2220115A2 (en) * | 2007-12-13 | 2010-08-25 | Glaxo Group Limited | Polypeptides, antibody variable domains & antagonists |
| PT3943069T (pt) | 2009-03-17 | 2025-02-21 | Nicox Ophthalmics Inc | Formulações oftálmicas de cetirizina e métodos de utilização |
| US8569273B2 (en) * | 2009-03-17 | 2013-10-29 | Aciex Therapeutics, Inc. | Ophthalmic formulations of cetirizine and methods of use |
| ES2662710T3 (es) | 2010-05-24 | 2018-04-09 | Swedish Oat Fiber Ab | Dispersión acuosa que comprende galactolípidos y método de producción de la misma |
| CN103260623B (zh) * | 2010-10-06 | 2016-11-02 | 伊斯塔制药公司 | 贝托斯汀组合物 |
| JP5683719B2 (ja) * | 2011-01-04 | 2015-03-11 | イスタ・ファーマシューティカルズ・インコーポレイテッドＩｓｔａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | ベポタスチン組成物 |
| AU2011353698B2 (en) | 2011-01-05 | 2017-05-11 | Livon Laboratories | Methods of making liposomes, liposome compositions made by the methods, and methods of using the same |
| CA2841644A1 (en) | 2011-08-02 | 2013-02-07 | Cipla Limited | Pharmaceutical composition comprising ebastine and fluticasone |
| CN102614177B (zh) * | 2012-03-06 | 2014-08-06 | 北京伟峰益民科技有限公司 | 卢帕他定在制备治疗慢性阻塞性肺病药物组合物中的应用 |
| CN103830729A (zh) * | 2012-11-26 | 2014-06-04 | 天津金耀集团有限公司 | 氟替卡松及其酯与h1受体拮抗剂的吸入剂 |
| EP2968323A4 (en) | 2013-03-13 | 2016-12-14 | Flatley Discovery Lab | PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS |
| KR102226833B1 (ko) * | 2013-06-28 | 2021-03-12 | 한미약품 주식회사 | 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형 |
| US10653661B2 (en) | 2013-10-04 | 2020-05-19 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10758550B2 (en) | 2013-10-04 | 2020-09-01 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| MX2015009429A (es) | 2013-10-04 | 2015-10-09 | Glenmark Pharmaceuticals Ltd | Tratamiento de rinitis alergica utilizando una combinacion de mometasona y olopatadina. |
| US11679210B2 (en) | 2014-10-03 | 2023-06-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
| CN104997734A (zh) * | 2015-06-25 | 2015-10-28 | 广州艾格生物科技有限公司 | 一种富马酸卢帕他定颗粒剂及制备方法 |
| SG10201912650QA (en) * | 2015-12-17 | 2020-02-27 | Univ Nanyang Tech | Nanoliposomes comprising corticosteroid as medicaments and methods to prepare them |
| WO2018119413A1 (en) * | 2016-12-22 | 2018-06-28 | Lipidair, Llc | Targeted delivery methods and compositions for antihistamines |
| CN109125265A (zh) * | 2017-06-13 | 2019-01-04 | 佛山英特医药科技有限公司 | 布地奈德脂质复合物及其制备方法 |
| US12303635B2 (en) | 2018-04-16 | 2025-05-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
| US11304901B2 (en) * | 2019-08-28 | 2022-04-19 | Anovent Pharmaceutical (U.S.), Llc | Liposome formulation of fluticasone furoate and method of preparation |
| WO2021110173A1 (en) * | 2019-12-06 | 2021-06-10 | Anovent Pharmaceuticals Co., Ltd | Liposome formulation of fluticasone propionate |
| AU2021291684A1 (en) | 2020-06-15 | 2022-12-08 | Alkem Laboratories Limited | Combination of alcaftadine and a corticosteroid |
| EP4236949A4 (en) * | 2020-10-30 | 2024-09-25 | The Board of Trustees of the Leland Stanford Junior University | DRUGS TARGETING INFLAMMATION FOR THE TREATMENT OF OSTEOARTHRITIS AND OTHER INFLAMMATORY DISEASES |
| US20220280422A1 (en) * | 2021-03-04 | 2022-09-08 | Innovation for Success, LLC | Solubilized melatonin |
| US20240173331A1 (en) | 2021-04-01 | 2024-05-30 | Alkem Laboratories Limited | Nasal compositions comprising alcaftadine |
| CN114392235B (zh) * | 2022-01-28 | 2023-06-27 | 成都大学 | 盐酸西替利嗪眼用脂质体、原位凝胶及其制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1523965A (en) * | 1976-03-19 | 1978-09-06 | Ici Ltd | Pharmaceutical compositions containing steroids |
| US5141674A (en) * | 1984-03-08 | 1992-08-25 | Phares Pharmaceutical Research N.V. | Methods of preparing pro-liposome dispersions and aerosols |
| US4839175A (en) * | 1986-07-28 | 1989-06-13 | Liposome Technology, Inc. | Liposomes with enhanced retention on mucosal tissue |
| US4962022A (en) * | 1986-09-22 | 1990-10-09 | Becton Dickinson And Company | Storage and use of liposomes |
| US5049388A (en) * | 1986-11-06 | 1991-09-17 | Research Development Foundation | Small particle aerosol liposome and liposome-drug combinations for medical use |
| US5422120A (en) * | 1988-05-30 | 1995-06-06 | Depotech Corporation | Heterovesicular liposomes |
| DE3836892A1 (de) * | 1988-10-29 | 1990-05-03 | Nattermann A & Cie | Parenteral applizierbare, stabile arzneimittelloesungen |
| US5498420A (en) * | 1991-04-12 | 1996-03-12 | Merz & Co. Gmbh & Co. | Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions |
| JP3383704B2 (ja) * | 1993-04-02 | 2003-03-04 | わかもと製薬株式会社 | 安定なリポソーム水分散液 |
| CA2120197A1 (en) * | 1993-04-02 | 1994-10-03 | Kenji Endo | Stable aqueous dispersions containing liposomes |
| DE4341472A1 (de) * | 1993-12-02 | 1995-06-08 | Schering Ag | Verfahren zur Erhöhung der Stabilität von hydrophile Wirkstoffe enthaltenden Liposomensuspensionen |
| DE4430593C2 (de) * | 1994-08-20 | 1999-01-14 | Max Delbrueck Centrum | Verfahren zur Herstellung von Liposomal verkapseltem Taxol |
| US6132765A (en) * | 1996-04-12 | 2000-10-17 | Uroteq Inc. | Drug delivery via therapeutic hydrogels |
| CA2256721A1 (en) * | 1996-06-04 | 1997-12-11 | The Procter & Gamble Company | A nasal spray containing an intranasal steroid and an antihistamine |
| JP4457422B2 (ja) * | 1998-01-09 | 2010-04-28 | 大正製薬株式会社 | 点鼻組成物 |
| US6726925B1 (en) * | 1998-06-18 | 2004-04-27 | Duke University | Temperature-sensitive liposomal formulation |
| CZ20012038A3 (cs) * | 1998-12-23 | 2001-09-12 | Idea Ag | Zdokonalený přípravek pro topické, neinvazivní použití in vivo |
| US20030054030A1 (en) * | 2001-09-13 | 2003-03-20 | Gary Gordon | Method and compositions for the treatment of pruritus |
| ATE317268T1 (de) * | 2001-12-05 | 2006-02-15 | Alcon Inc | Verwendung eines h1-antagonisten und von rimexolon als sicheres steroid zur behandlung von rhinitis |
| AU2003252187A1 (en) * | 2002-05-15 | 2003-12-02 | Engelbrecht, Edna | Topical composition for the treatment of inflammatory conditions of the skin |
| US20040198743A1 (en) * | 2003-01-31 | 2004-10-07 | Schering Corporation | Methods for treating allergic skin and allergic ocular conditions using combinations of histamine receptor antagonists |
| EP1643972A4 (en) * | 2003-06-27 | 2010-01-20 | Smithkline Beecham Corp | STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD |
| TW200522932A (en) * | 2003-09-15 | 2005-07-16 | Combinatorx Inc | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
| US20050112199A1 (en) * | 2003-09-24 | 2005-05-26 | Mahesh Padval | Therapeutic regimens for administering drug combinations |
| WO2005039533A1 (en) * | 2003-10-15 | 2005-05-06 | Medigene Ag | Method of administering cationic liposomes comprising an active drug |
-
2006
- 2006-08-31 PT PT67792440T patent/PT1919450E/pt unknown
- 2006-08-31 PL PL06779244T patent/PL1919450T3/pl unknown
- 2006-08-31 SI SI200631823T patent/SI1919450T1/sl unknown
- 2006-08-31 RU RU2008112167/15A patent/RU2444351C2/ru not_active IP Right Cessation
- 2006-08-31 EP EP06779244.0A patent/EP1919450B1/en not_active Not-in-force
- 2006-08-31 ES ES06779244.0T patent/ES2498795T3/es active Active
- 2006-08-31 US US11/991,091 patent/US20090324699A1/en not_active Abandoned
- 2006-08-31 BR BRPI0615032-2A patent/BRPI0615032A2/pt active Search and Examination
- 2006-08-31 DK DK06779244.0T patent/DK1919450T3/da active
- 2006-08-31 CA CA2616515A patent/CA2616515C/en not_active Expired - Fee Related
- 2006-08-31 CN CNA2006800321913A patent/CN101257891A/zh active Pending
- 2006-08-31 WO PCT/GB2006/003222 patent/WO2007026151A1/en not_active Ceased
- 2006-08-31 JP JP2008528575A patent/JP5393151B2/ja not_active Expired - Fee Related
-
2013
- 2013-07-30 US US13/954,694 patent/US20140065203A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20090324699A1 (en) | 2009-12-31 |
| WO2007026151A1 (en) | 2007-03-08 |
| RU2008112167A (ru) | 2009-10-10 |
| RU2444351C2 (ru) | 2012-03-10 |
| CA2616515A1 (en) | 2007-03-08 |
| US20140065203A1 (en) | 2014-03-06 |
| JP5393151B2 (ja) | 2014-01-22 |
| PL1919450T3 (pl) | 2014-11-28 |
| BRPI0615032A2 (pt) | 2011-04-26 |
| SI1919450T1 (sl) | 2014-10-30 |
| EP1919450A1 (en) | 2008-05-14 |
| ES2498795T3 (es) | 2014-09-25 |
| PT1919450E (pt) | 2014-09-10 |
| HK1115314A1 (en) | 2008-11-28 |
| EP1919450B1 (en) | 2014-06-11 |
| CA2616515C (en) | 2014-09-23 |
| CN101257891A (zh) | 2008-09-03 |
| JP2009507009A (ja) | 2009-02-19 |
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