DK1937262T3 - Sammensætning til anvendelse i behandling af gastrointestinal dysmotilitet - Google Patents

Sammensætning til anvendelse i behandling af gastrointestinal dysmotilitet Download PDF

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Publication number
DK1937262T3
DK1937262T3 DK06825239.4T DK06825239T DK1937262T3 DK 1937262 T3 DK1937262 T3 DK 1937262T3 DK 06825239 T DK06825239 T DK 06825239T DK 1937262 T3 DK1937262 T3 DK 1937262T3
Authority
DK
Denmark
Prior art keywords
motility
gastrointestinal
dye
treatment
composition
Prior art date
Application number
DK06825239.4T
Other languages
English (en)
Inventor
Rakesh Datta
Zheng Xin Dong
Original Assignee
Ipsen Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Pharma filed Critical Ipsen Pharma
Application granted granted Critical
Publication of DK1937262T3 publication Critical patent/DK1937262T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2264—Obesity-gene products, e.g. leptin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK06825239.4T 2005-09-29 2006-09-28 Sammensætning til anvendelse i behandling af gastrointestinal dysmotilitet DK1937262T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72191605P 2005-09-29 2005-09-29
PCT/US2006/038027 WO2007041278A2 (en) 2005-09-29 2006-09-28 Composition and methods for stimulating gastrointestinal motility

Publications (1)

Publication Number Publication Date
DK1937262T3 true DK1937262T3 (da) 2019-07-15

Family

ID=37906731

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06825239.4T DK1937262T3 (da) 2005-09-29 2006-09-28 Sammensætning til anvendelse i behandling af gastrointestinal dysmotilitet

Country Status (14)

Country Link
US (6) US7932231B2 (da)
EP (2) EP3586846A1 (da)
JP (4) JP5230430B2 (da)
CN (3) CN103251933A (da)
CA (1) CA2625447C (da)
CY (1) CY1122134T1 (da)
DK (1) DK1937262T3 (da)
ES (1) ES2740108T3 (da)
HU (1) HUE044391T2 (da)
PL (1) PL1937262T3 (da)
PT (1) PT1937262T (da)
RU (2) RU2420305C2 (da)
SI (1) SI1937262T1 (da)
WO (1) WO2007041278A2 (da)

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CN101282738B (zh) * 2005-09-28 2015-09-16 益普生制药股份有限公司 生长素释放肽类似物
DK1937262T3 (da) * 2005-09-29 2019-07-15 Ipsen Pharma Sammensætning til anvendelse i behandling af gastrointestinal dysmotilitet
ES2602789T3 (es) 2007-02-09 2017-02-22 Ocera Therapeutics, Inc. Productos intermedios conectores para la síntesis de moduladores macrocíclicos del receptor de la grelina
AU2013201451B2 (en) * 2007-08-08 2015-07-30 Ipsen Pharma S.A.S. Method for inhibiting inflammation and pre-inflammatory cytokine/chemokine expression using a ghrelin analogue
TW200916113A (en) * 2007-08-08 2009-04-16 Sod Conseils Rech Applic Method for inhibiting inflammation and pro-inflammatory cytokine/chemokine expression using a ghrelin analogue
CN101951937A (zh) * 2007-12-21 2011-01-19 赫尔辛医疗股份公司 使用伊帕瑞林刺激胃肠系统动力的方法
JP2012504619A (ja) 2008-10-03 2012-02-23 ザ ジョンズ ホプキンス ユニバーシティ 肥満および糖尿病の有望な治療薬としてのグレリンｏ−アシルトランスフェラーゼ阻害剤の合成方法および使用方法
BR112012023303A2 (pt) * 2010-03-15 2020-08-25 Ipsen Pharma S.A.S. composição farmacêutica de ligantes do receptor do secretagogo do hormônio de crescimento.
RU2475757C1 (ru) * 2012-02-02 2013-02-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера" Министерства здравоохранения и социального развития Российской Федерации Способ прогнозирования тяжести течения послеоперационного периода у больных калькулезным холециститом
JP2015510505A (ja) * 2012-02-03 2015-04-09 ジーランド ファーマ アクティーゼルスカブ グレリン類似体
WO2014156339A1 (ja) * 2013-03-25 2014-10-02 ゼリア新薬工業株式会社 食後期の胃運動亢進剤
US20170218015A1 (en) 2014-03-04 2017-08-03 Motus Therapeutics, Inc. Process for the liquid phase synthesis of h-inp-(d)bal-(d)trp-phe-apc-nh2, and pharmaceutically acceptable salts thereof
CN113072617B (zh) * 2021-03-30 2023-08-08 成都诺和晟泰生物科技有限公司 一种多肽化合物及其应用
CN114805487B (zh) * 2022-06-07 2024-03-12 成都诺和晟泰生物科技有限公司 一种多肽化合物及其应用

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CN101282738B (zh) * 2005-09-28 2015-09-16 益普生制药股份有限公司 生长素释放肽类似物
DK1937262T3 (da) * 2005-09-29 2019-07-15 Ipsen Pharma Sammensætning til anvendelse i behandling af gastrointestinal dysmotilitet
ES2424970T3 (es) * 2006-03-10 2013-10-10 Ipsen Pharma Uso de un agonista de la grelina para mejorar los efectos catabólicos del tratamiento con glucocorticoides
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TW200916113A (en) * 2007-08-08 2009-04-16 Sod Conseils Rech Applic Method for inhibiting inflammation and pro-inflammatory cytokine/chemokine expression using a ghrelin analogue
BR112012023303A2 (pt) * 2010-03-15 2020-08-25 Ipsen Pharma S.A.S. composição farmacêutica de ligantes do receptor do secretagogo do hormônio de crescimento.
KR101996700B1 (ko) 2011-12-23 2019-07-04 입센 메뉴팩츄링 아일랜드 리미티드 치료 펩티드의 합성 방법

Also Published As

Publication number Publication date
CN105381453B9 (zh) 2019-01-11
JP2015038116A (ja) 2015-02-26
US20090304724A1 (en) 2009-12-10
HUE044391T2 (hu) 2019-10-28
US20150218245A1 (en) 2015-08-06
US20110166069A1 (en) 2011-07-07
EP3586846A1 (en) 2020-01-01
US20190248861A1 (en) 2019-08-15
EP1937262B1 (en) 2019-05-08
CA2625447A1 (en) 2007-04-12
WO2007041278A2 (en) 2007-04-12
CY1122134T1 (el) 2020-11-25
ES2740108T3 (es) 2020-02-05
CN105381453A (zh) 2016-03-09
RU2008116837A (ru) 2009-11-10
RU2011103062A (ru) 2012-08-10
JP2017095494A (ja) 2017-06-01
US20170037104A1 (en) 2017-02-09
CA2625447C (en) 2015-06-09
EP1937262A2 (en) 2008-07-02
JP2013035856A (ja) 2013-02-21
RU2420305C2 (ru) 2011-06-10
PL1937262T3 (pl) 2019-10-31
CN105381453B (zh) 2018-11-13
US7932231B2 (en) 2011-04-26
JP5960563B2 (ja) 2016-08-02
EP1937262A4 (en) 2014-09-24
JP5230430B2 (ja) 2013-07-10
US8981054B2 (en) 2015-03-17
WO2007041278B1 (en) 2007-12-06
US20200347110A1 (en) 2020-11-05
RU2566708C2 (ru) 2015-10-27
CN103251933A (zh) 2013-08-21
JP2009510098A (ja) 2009-03-12
WO2007041278A3 (en) 2007-10-04
CN101287464A (zh) 2008-10-15
SI1937262T1 (sl) 2019-09-30
US9499599B2 (en) 2016-11-22
JP6419864B2 (ja) 2018-11-07
PT1937262T (pt) 2019-08-21

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