DK194585A - Nitrosourinstofderivater, fremgangsmaade til fremstilling deraf og laegemidler, der indeholder dem - Google Patents

Nitrosourinstofderivater, fremgangsmaade til fremstilling deraf og laegemidler, der indeholder dem Download PDF

Info

Publication number: DK194585A
Authority: DK; Denmark
Prior art keywords: formula; hydrogen; represent; hydrogen atom; group
Prior art date: 1983-08-30

Application number

DK194585A

Other languages

English (en)

Other versions

DK194585D0 (da

Inventor

Pierre Roger

Patrick Choay

Claude Monneret

Jean-Paul Fournier

Original Assignee

Dropic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-08-30

Filing date

1985-04-30

Publication date

1985-04-30

1985-04-30 Application filed by Dropic filed Critical Dropic

1985-04-30 Publication of DK194585A publication Critical patent/DK194585A/da

1985-04-30 Publication of DK194585D0 publication Critical patent/DK194585D0/da

Links

238000000034 method Methods 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
239000004615 ingredient Substances 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract description 8
229910052739 hydrogen Inorganic materials 0.000 abstract description 6
239000001257 hydrogen Substances 0.000 abstract description 6
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract description 4
125000000217 alkyl group Chemical group 0.000 abstract description 3
125000004432 carbon atom Chemical group C* 0.000 abstract description 3
230000000259 anti-tumor effect Effects 0.000 abstract description 2
150000001875 compounds Chemical class 0.000 abstract description 2
229910052736 halogen Inorganic materials 0.000 abstract description 2
150000002367 halogens Chemical class 0.000 abstract description 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
OSTGTTZJOCZWJG-UHFFFAOYSA-N nitrosourea Chemical class NC(=O)N=NO OSTGTTZJOCZWJG-UHFFFAOYSA-N 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

Description

hvor Hal er halogen, og og/eller R^ hver kan repræsentere et hydrogenatom eller en alkylgruppe med 1-6 carbonatomer, R’ og R" kan repræsentere hydrogen eller OH, med det forbehold, at i det mindste X repræsenterer

hvor Rj repræsenterer

eller Y repræsenterer

hvor R'^ repræsenterer

og med det forbehold, at enten R' eller R" er hydrogen, og idet R' og R" ikke samtidigt kan være hydrogen.

Forbindelserne har antitumor-virkning.

DK194585A 1983-08-30 1985-04-30 Nitrosourinstofderivater, fremgangsmaade til fremstilling deraf og laegemidler, der indeholder dem DK194585D0 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR8313878		1983-08-30
FR8313878A FR2551068B1 (fr)	1983-08-30	1983-08-30	Nouveaux derives de nitrosourees, leurs procedes de preparation et compositions therapeutiques les contenant
PCT/EP1984/000260 WO1985001050A1 (en)	1983-08-30	1984-08-29	Nitrosourea derivatives, process for their preparation and medicaments containing them
EP8400260		1984-08-29

Publications (2)

Publication Number	Publication Date
DK194585A true DK194585A (da)	1985-04-30
DK194585D0 DK194585D0 (da)	1985-04-30

Family

ID=9291872

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK194585A DK194585D0 (da)	1983-08-30	1985-04-30	Nitrosourinstofderivater, fremgangsmaade til fremstilling deraf og laegemidler, der indeholder dem

Country Status (15)

Country	Link
EP (1)	EP0143675B1 (da)
JP (1)	JPS60502105A (da)
KR (1)	KR920001690B1 (da)
AT (1)	ATE50264T1 (da)
CA (1)	CA1257587A (da)
DE (1)	DE3481305D1 (da)
DK (1)	DK194585D0 (da)
ES (1)	ES8602031A1 (da)
FR (1)	FR2551068B1 (da)
GR (1)	GR80249B (da)
IL (1)	IL72817A (da)
NZ (1)	NZ209397A (da)
PT (1)	PT79158B (da)
WO (1)	WO1985001050A1 (da)
ZA (1)	ZA846783B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2614303B1 (fr) *	1987-04-22	1990-06-08	Sanofi Sa	Derives de nitrosourees, leur nouveau procede de preparation et leurs applications therapeutiques.
FR2614304A1 (fr) *	1987-04-22	1988-10-28	Sanofi Sa	Derives de nitrosourees, leur nouveau procede de preparation et leurs applications therapeutiques.
DE19524515A1 (de) *	1995-07-05	1997-01-09	Deutsches Krebsforsch	Saccharid-Konjugate
WO1998043628A1 (fr) *	1997-04-02	1998-10-08	Viktor Veniaminovich Tets	Remede antitumoral (chlonidane)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3940383A (en) *	1974-12-12	1976-02-24	Stanford Research Institute	Streptozotocin analogs
JPS554324A (en) *	1978-06-26	1980-01-12	Kaken Pharmaceut Co Ltd	Novel glycopyranosidoamine derivative, its preparation, and antitumor agent comprising it as active constituent
JPS5681596A (en) *	1979-12-07	1981-07-03	Tokyo Tanabe Co Ltd	Glucopyranose-nitrosourea derivative, carcinostatic agent consisting of the same and preparation
JPS57200397A (en) *	1981-06-03	1982-12-08	Akira Kimura	Novel aldohexopyranose-, aldopentopyranose-, or and medicament composition comprising it aldopentofuranose- nitrosourea compound, its preparation

1983
- 1983-08-30 FR FR8313878A patent/FR2551068B1/fr not_active Expired
1984
- 1984-08-29 JP JP59503417A patent/JPS60502105A/ja active Pending
- 1984-08-29 WO PCT/EP1984/000260 patent/WO1985001050A1/en not_active Ceased
- 1984-08-29 KR KR1019850700021A patent/KR920001690B1/ko not_active Expired
- 1984-08-30 DE DE8484401743T patent/DE3481305D1/de not_active Expired - Fee Related
- 1984-08-30 ZA ZA846783A patent/ZA846783B/xx unknown
- 1984-08-30 GR GR80249A patent/GR80249B/el unknown
- 1984-08-30 ES ES535903A patent/ES8602031A1/es not_active Expired
- 1984-08-30 CA CA000462200A patent/CA1257587A/fr not_active Expired
- 1984-08-30 AT AT84401743T patent/ATE50264T1/de not_active IP Right Cessation
- 1984-08-30 IL IL72817A patent/IL72817A/xx unknown
- 1984-08-30 PT PT79158A patent/PT79158B/pt not_active IP Right Cessation
- 1984-08-30 NZ NZ209397A patent/NZ209397A/en unknown
- 1984-08-30 EP EP84401743A patent/EP0143675B1/fr not_active Expired - Lifetime
1985
- 1985-04-30 DK DK194585A patent/DK194585D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
NZ209397A (en)	1988-04-29
AU580009B2 (en)	1988-12-22
ES535903A0 (es)	1985-12-01
PT79158B (fr)	1986-08-19
FR2551068B1 (fr)	1986-03-21
EP0143675A1 (fr)	1985-06-05
CA1257587A (fr)	1989-07-18
WO1985001050A1 (en)	1985-03-14
JPS60502105A (ja)	1985-12-05
DE3481305D1 (de)	1990-03-15
ZA846783B (en)	1985-04-24
EP0143675B1 (fr)	1990-02-07
IL72817A (en)	1989-09-10
KR850700031A (ko)	1985-10-21
DK194585D0 (da)	1985-04-30
KR920001690B1 (ko)	1992-02-22
FR2551068A1 (fr)	1985-03-01
AU3392684A (en)	1985-03-29
ATE50264T1 (de)	1990-02-15
PT79158A (fr)	1984-09-01
ES8602031A1 (es)	1985-12-01
GR80249B (en)	1984-12-14
IL72817A0 (en)	1984-11-30

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Legal Events

Date	Code	Title	Description
1993-08-23	AHS	Application shelved for other reasons than non-payment