DK1947171T3 - Oprensede bakterieminiceller - Google Patents

Oprensede bakterieminiceller

Info

Publication number
DK1947171T3
DK1947171T3 DK08101712.1T DK08101712T DK1947171T3 DK 1947171 T3 DK1947171 T3 DK 1947171T3 DK 08101712 T DK08101712 T DK 08101712T DK 1947171 T3 DK1947171 T3 DK 1947171T3
Authority
DK
Denmark
Prior art keywords
minicells
provides
minicell preparations
purified minicell
parent bacterial
Prior art date
Application number
DK08101712.1T
Other languages
English (en)
Inventor
Himanshu Brahmbhatt
Jennifer Macdiarmid
Original Assignee
Engeneic Molecular Delivery Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engeneic Molecular Delivery Pty Ltd filed Critical Engeneic Molecular Delivery Pty Ltd
Application granted granted Critical
Publication of DK1947171T3 publication Critical patent/DK1947171T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK08101712.1T 2003-06-24 2004-06-23 Oprensede bakterieminiceller DK1947171T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/602,021 US7611885B2 (en) 2003-06-24 2003-06-24 Pharmaceutically compatible method for purifying intact bacterial minicells
EP04743793A EP1636344B1 (en) 2003-06-24 2004-06-23 Pharmaceutically compatible method for purifying intact bacterial minicells

Publications (1)

Publication Number Publication Date
DK1947171T3 true DK1947171T3 (da) 2011-09-19

Family

ID=33539477

Family Applications (3)

Application Number Title Priority Date Filing Date
DK04743793.4T DK1636344T3 (da) 2003-06-24 2004-06-23 Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller
DK10180971.3T DK2333044T3 (da) 2003-06-24 2004-06-23 Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller
DK08101712.1T DK1947171T3 (da) 2003-06-24 2004-06-23 Oprensede bakterieminiceller

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK04743793.4T DK1636344T3 (da) 2003-06-24 2004-06-23 Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller
DK10180971.3T DK2333044T3 (da) 2003-06-24 2004-06-23 Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller

Country Status (18)

Country Link
US (4) US7611885B2 (da)
EP (3) EP1636344B1 (da)
JP (1) JP4834544B2 (da)
CN (2) CN1809629B (da)
AT (2) ATE513032T1 (da)
AU (2) AU2004249970B2 (da)
CA (2) CA2780843C (da)
CY (1) CY1118218T1 (da)
DE (1) DE602004026051D1 (da)
DK (3) DK1636344T3 (da)
ES (3) ES2342830T3 (da)
HU (1) HUE030642T2 (da)
MX (1) MXPA05013620A (da)
NZ (1) NZ544653A (da)
PL (2) PL1947171T3 (da)
PT (2) PT2333044T (da)
SI (1) SI2333044T1 (da)
WO (1) WO2004113507A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1446489T3 (da) * 2001-10-15 2012-05-14 Engeneic Molecular Delivery Pty Ltd Intakte miniceller som vektorer for DNA-overførsel og genterapi in vitro og in vivo
US7611885B2 (en) 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
NZ547983A (en) 2003-12-09 2009-05-31 Engeneic Molecular Delivery Pty Ltd Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells
US8772013B2 (en) * 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
AU2005215254B2 (en) 2004-02-02 2009-11-12 Engeneic Molecular Delivery Pty Ltd Compositions and methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
CA2577938C (en) 2004-08-26 2013-04-16 Himanshu Brahmbhatt Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells
US9878043B2 (en) 2006-06-23 2018-01-30 Engeneic Molecular Delivery Pty Ltd Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells
PT2145002E (pt) 2007-03-30 2015-04-29 Engeneic Molecular Delivery Pty Ltd Mínicélulas derivadas de bactérias, intactas, que compreendem ácidos nucleicos funcionais livres de plasmídeos, para administração in vivo em células de mamíferos
KR101623999B1 (ko) 2008-06-25 2016-05-24 벡션 테라퓨틱스 엘엘씨 조절된 유전자 자살 메커니즘 조성물 및 방법
WO2010006377A1 (en) 2008-07-17 2010-01-21 Nutripep Pty Limited Therapeutic agents
AU2010245860B2 (en) * 2009-05-07 2015-07-16 Biomerieux, Inc. Methods for antimicrobial resistance determination
US20120142089A1 (en) * 2010-12-01 2012-06-07 Samsung Electronics Co., Ltd. Method of separating target cell in biological sample
US9624474B2 (en) * 2010-12-01 2017-04-18 Samsung Electronics Co, Ltd. Method of separating target cell in biological sample
KR20140102294A (ko) 2011-12-13 2014-08-21 엔진아이씨 몰레큘러 딜리버리 피티와이 리미티드 뇌 종양에 대한 치료제의 전달을 위한 박테리아 유래된, 무손상 미니세포
JP6249447B2 (ja) 2012-01-24 2017-12-20 インターケー・ペプチド・セラピューティクス・リミテッド 癌治療用ペプチド剤
CA2926161C (en) 2013-10-04 2023-03-14 Engeneic Molecular Delivery Pty Ltd Combination tumor treatment with drug-loaded, bispecific ligand-targeted minicells and interferon-gamma
US10328159B2 (en) 2014-10-03 2019-06-25 Engenic Molecular Delivery Pty Ltd. Enhanced loading of intact, bacterially derived vesicles with small molecule compounds
AU2016301302B2 (en) 2015-08-04 2023-01-12 Vaxiion Therapeutics, Llc Ionizing irradiation sterilization of bacterial minicell-based biopharmaceuticals and methods of use
NZ752371A (en) 2016-10-06 2026-03-27 Engeneic Molecular Delivery Pty Ltd Bacterial minicells for delivering nucleic acid adjuvants and methods of using the same
CA3100072A1 (en) 2018-05-15 2019-11-21 Interk Peptide Therapeutics Limited Activating agents
US11504402B2 (en) 2018-07-23 2022-11-22 Engenelc Molecular Delivery Pty Ltd Compositions comprising bacterially derived minicells and methods of using the same
EP3906053A4 (en) 2019-01-04 2023-01-11 EnGeneIC Molecular Delivery Pty Ltd. ENCAPSULATED GLYCOLIPID ANTIGENS FOR THE TREATMENT OF NEOPLASTIC DISEASES
US12357687B2 (en) 2020-03-24 2025-07-15 Engeneic Molecular Delivery Pty Ltd Compositions and vaccines for treating and/or preventing viral infections, and methods of using the same
WO2021257788A1 (en) * 2020-06-17 2021-12-23 Flagship Pioneering Innovations Vi, Llc Methods for manufacturing adas
CN113186100B (zh) * 2021-05-11 2022-10-04 中国科学院青岛生物能源与过程研究所 一种富集污水微生物以用于单细胞精度表型测量和分选的试剂盒及方法
US12551550B2 (en) 2021-07-22 2026-02-17 Engeneic Molecular Delivery Pty Ltd Compositions and vaccines for treating and/or preventing coronavirus variant infections and methods of using the same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311797A (en) 1979-09-18 1982-01-19 University Of Saskatchewan Anucleated live E. coli vaccine
CA2370628A1 (en) 1999-04-21 2000-10-26 American Home Products Corporation Methods and compositions for inhibiting the function of polynucleotide sequences
WO2002016590A2 (en) * 2000-08-21 2002-02-28 Clonex Development, Inc. Methods and compositions for increasing protein yield from a cell culture
CA2440649A1 (en) 2001-03-07 2002-09-19 Children's Medical Center Corporation Method to screen peptide display libraries using minicell display
US7011946B2 (en) * 2001-05-22 2006-03-14 Trustees Of Tufts College In vivo assay for identification of antimicrobial agents
US20030194798A1 (en) * 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
DK1446489T3 (da) 2001-10-15 2012-05-14 Engeneic Molecular Delivery Pty Ltd Intakte miniceller som vektorer for DNA-overførsel og genterapi in vitro og in vivo
AU2002318168B2 (en) 2002-02-25 2007-12-13 Vaxiion Therapeutics, Llc Minicell compositions and methods
US7611885B2 (en) * 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
NZ547983A (en) * 2003-12-09 2009-05-31 Engeneic Molecular Delivery Pty Ltd Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells
US8772013B2 (en) * 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
CA2577938C (en) * 2004-08-26 2013-04-16 Himanshu Brahmbhatt Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells
DE602005023345D1 (de) 2004-12-17 2010-10-14 Beth Israel Hospital Zusammensetzungen für bakteriell vermitteltes gen-silencing sowie verfahren zur verwendung davon
US9878043B2 (en) * 2006-06-23 2018-01-30 Engeneic Molecular Delivery Pty Ltd Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells

Also Published As

Publication number Publication date
EP1636344A1 (en) 2006-03-22
HK1089207A1 (en) 2006-11-24
US20110177185A1 (en) 2011-07-21
AU2004249970B2 (en) 2009-09-10
DE602004026051D1 (de) 2010-04-29
ES2602572T3 (es) 2017-02-21
JP4834544B2 (ja) 2011-12-14
US7611885B2 (en) 2009-11-03
HUE030642T2 (en) 2017-06-28
MXPA05013620A (es) 2006-02-24
PL2333044T3 (pl) 2017-02-28
PT2333044T (pt) 2016-11-21
CA2780843A1 (en) 2012-08-13
CN1809629B (zh) 2013-06-12
PL1947171T3 (pl) 2011-12-30
ES2367535T3 (es) 2011-11-04
EP1636344A4 (en) 2006-07-19
ES2342830T3 (es) 2010-07-15
EP1947171B1 (en) 2011-06-15
US20040265994A1 (en) 2004-12-30
AU2009239519A1 (en) 2009-12-10
WO2004113507A9 (en) 2006-08-24
CA2530055A1 (en) 2004-12-29
ATE513032T1 (de) 2011-07-15
AU2004249970A1 (en) 2004-12-29
SI2333044T1 (sl) 2016-12-30
CA2780843C (en) 2013-12-10
PT1947171E (pt) 2011-09-07
CN103361286B (zh) 2016-12-28
AU2009239519B2 (en) 2010-04-22
WO2004113507A1 (en) 2004-12-29
US8003091B2 (en) 2011-08-23
JP2007520201A (ja) 2007-07-26
HK1158261A1 (en) 2012-07-13
HK1121190A1 (en) 2009-04-17
DK2333044T3 (da) 2016-12-12
CN103361286A (zh) 2013-10-23
US20070241067A1 (en) 2007-10-18
US10076545B2 (en) 2018-09-18
CN1809629A (zh) 2006-07-26
NZ544653A (en) 2009-02-28
EP2333044A1 (en) 2011-06-15
DK1636344T3 (da) 2010-05-31
ATE461269T1 (de) 2010-04-15
CA2530055C (en) 2012-10-02
CY1118218T1 (el) 2017-06-28
US8449877B2 (en) 2013-05-28
EP1947171A1 (en) 2008-07-23
US20130236422A1 (en) 2013-09-12
EP1636344B1 (en) 2010-03-17
EP2333044B1 (en) 2016-08-17

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