DK1961735T3 - Fremgangsmåde til fremstilling af (2R,3S)-3-phenylisoserinmethylesteracetatsalt - Google Patents
Fremgangsmåde til fremstilling af (2R,3S)-3-phenylisoserinmethylesteracetatsaltInfo
- Publication number
- DK1961735T3 DK1961735T3 DK07003642.1T DK07003642T DK1961735T3 DK 1961735 T3 DK1961735 T3 DK 1961735T3 DK 07003642 T DK07003642 T DK 07003642T DK 1961735 T3 DK1961735 T3 DK 1961735T3
- Authority
- DK
- Denmark
- Prior art keywords
- methyl ester
- acetate salt
- preparation
- ester acetate
- phenylisoserine
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- GPHBGDVLVCUIOU-OULXEKPRSA-N acetic acid;methyl (2r,3s)-3-amino-2-hydroxy-3-phenylpropanoate Chemical compound CC(O)=O.COC(=O)[C@H](O)[C@@H](N)C1=CC=CC=C1 GPHBGDVLVCUIOU-OULXEKPRSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/08—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07003642A EP1961735B1 (en) | 2007-02-22 | 2007-02-22 | Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1961735T3 true DK1961735T3 (da) | 2010-03-29 |
Family
ID=38230004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07003642.1T DK1961735T3 (da) | 2007-02-22 | 2007-02-22 | Fremgangsmåde til fremstilling af (2R,3S)-3-phenylisoserinmethylesteracetatsalt |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8106231B2 (da) |
| EP (1) | EP1961735B1 (da) |
| JP (1) | JP5352478B2 (da) |
| KR (1) | KR101499817B1 (da) |
| CN (1) | CN101675028B (da) |
| AT (1) | ATE449062T1 (da) |
| AU (1) | AU2008217318B2 (da) |
| CA (1) | CA2679159C (da) |
| DE (1) | DE602007003312D1 (da) |
| DK (1) | DK1961735T3 (da) |
| ES (1) | ES2333266T3 (da) |
| IL (1) | IL200537A (da) |
| MX (1) | MX2009008985A (da) |
| PL (1) | PL1961735T3 (da) |
| PT (1) | PT1961735E (da) |
| RU (1) | RU2459802C2 (da) |
| SI (1) | SI1961735T1 (da) |
| WO (1) | WO2008101608A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2380871B1 (en) * | 2010-04-15 | 2013-01-09 | Indena S.p.A. | A process for the preparation of isoserine derivatives |
| EP2399904A1 (en) * | 2010-05-26 | 2011-12-28 | Nabriva Therapeutics AG | Process for the preparation of pleuromutilins |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2275378A (en) * | 1937-09-10 | 1942-03-03 | Rohm & Haas | Polyalkylene ether disulphonyl halides and a process of making them |
| US4695589A (en) * | 1976-06-25 | 1987-09-22 | Sterling Drug Inc. | Alpha-(aminoalkyl-4-hydroxy-3-(alkylthio)benzenemethanols |
| FR2415640A1 (fr) * | 1978-01-27 | 1979-08-24 | Nativelle Sa Ets | Derives d'amino-3-cardenolides, procede pour leur preparation, et medicaments les contenant |
| ZA794872B (en) * | 1978-09-20 | 1980-11-26 | Schering Corp | A phenylalkylaminoethylsalicylamide,its preparation and pharmaceutical compositions containing it |
| FR2688499B1 (fr) * | 1992-03-10 | 1994-05-06 | Rhone Poulenc Rorer Sa | Procede de preparation de la beta-phenylisoserine et de ses analogues. |
| JPH06271512A (ja) * | 1993-03-22 | 1994-09-27 | Toray Ind Inc | 光学活性トランス−１，２−ジアミノ−４−シクロヘキセンの製造方法 |
| US6025516A (en) * | 1998-10-14 | 2000-02-15 | Chiragene, Inc. | Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes |
| JP4108483B2 (ja) * | 2001-03-23 | 2008-06-25 | サイノファーム タイワン リミテッド | タキサン誘導体の製造方法 |
| US7034178B2 (en) * | 2001-07-03 | 2006-04-25 | Altana Pharma Ag | Process for the production of 3-phenylisoserine |
| CN1315777C (zh) * | 2003-01-16 | 2007-05-16 | 东丽泛应化学(股) | 旋光二酰基酒石酸的回收方法 |
| FR2861073B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[heteroaryl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
| CN101027277A (zh) * | 2004-07-23 | 2007-08-29 | 帝斯曼知识产权资产管理有限公司 | (2r,3r)－2－羟基－3－氨基－3－芳基－丙酰胺和(2r,3r)－2－羟基－3－氨基－3－芳基－丙酸烷基酯的制备方法 |
| AR057061A1 (es) * | 2005-06-16 | 2007-11-14 | Altana Pharma Ag | Espiro-bencimidazoles farmaceuticamente activos y su uso en la fabricacion de medicamentos |
| JP2009114065A (ja) * | 2006-02-21 | 2009-05-28 | Kaneka Corp | （２ｒ，３ｒ）および（２ｓ，３ｓ）−３−フェニルイソセリン誘導体の製造法 |
-
2007
- 2007-02-22 EP EP07003642A patent/EP1961735B1/en active Active
- 2007-02-22 PT PT07003642T patent/PT1961735E/pt unknown
- 2007-02-22 PL PL07003642T patent/PL1961735T3/pl unknown
- 2007-02-22 SI SI200730119T patent/SI1961735T1/sl unknown
- 2007-02-22 AT AT07003642T patent/ATE449062T1/de active
- 2007-02-22 DE DE602007003312T patent/DE602007003312D1/de active Active
- 2007-02-22 ES ES07003642T patent/ES2333266T3/es active Active
- 2007-02-22 DK DK07003642.1T patent/DK1961735T3/da active
-
2008
- 2008-02-11 WO PCT/EP2008/001015 patent/WO2008101608A1/en not_active Ceased
- 2008-02-11 AU AU2008217318A patent/AU2008217318B2/en active Active
- 2008-02-11 CA CA2679159A patent/CA2679159C/en active Active
- 2008-02-11 US US12/527,887 patent/US8106231B2/en active Active
- 2008-02-11 MX MX2009008985A patent/MX2009008985A/es active IP Right Grant
- 2008-02-11 KR KR1020097017393A patent/KR101499817B1/ko active Active
- 2008-02-11 JP JP2009550666A patent/JP5352478B2/ja active Active
- 2008-02-11 CN CN2008800056940A patent/CN101675028B/zh active Active
- 2008-02-11 RU RU2009131595/04A patent/RU2459802C2/ru active
-
2009
- 2009-08-20 IL IL200537A patent/IL200537A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US8106231B2 (en) | 2012-01-31 |
| PT1961735E (pt) | 2009-12-21 |
| JP5352478B2 (ja) | 2013-11-27 |
| KR101499817B1 (ko) | 2015-03-06 |
| CA2679159C (en) | 2015-11-03 |
| EP1961735A1 (en) | 2008-08-27 |
| JP2010519262A (ja) | 2010-06-03 |
| RU2009131595A (ru) | 2011-02-27 |
| RU2459802C2 (ru) | 2012-08-27 |
| WO2008101608A1 (en) | 2008-08-28 |
| MX2009008985A (es) | 2009-09-02 |
| DE602007003312D1 (de) | 2009-12-31 |
| US20100168460A1 (en) | 2010-07-01 |
| AU2008217318A1 (en) | 2008-08-28 |
| AU2008217318B2 (en) | 2013-01-17 |
| CN101675028A (zh) | 2010-03-17 |
| KR20090113859A (ko) | 2009-11-02 |
| EP1961735B1 (en) | 2009-11-18 |
| HK1121735A1 (en) | 2009-04-30 |
| CA2679159A1 (en) | 2008-08-28 |
| SI1961735T1 (sl) | 2010-01-29 |
| IL200537A0 (en) | 2010-04-29 |
| ATE449062T1 (de) | 2009-12-15 |
| IL200537A (en) | 2013-03-24 |
| CN101675028B (zh) | 2013-01-30 |
| PL1961735T3 (pl) | 2010-04-30 |
| ES2333266T3 (es) | 2010-02-18 |
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