DK1977252T3 - Forbedret monocytaktiveringsprøve med bedre evne til påvisning af pyrogene ikke-endotoxin-kontaminanter i medicinske produkter - Google Patents

Forbedret monocytaktiveringsprøve med bedre evne til påvisning af pyrogene ikke-endotoxin-kontaminanter i medicinske produkter

Info

Publication number: DK1977252T3
Authority: DK; Denmark
Prior art keywords: detect; medical products; better ability; monocyte activation; activation test
Prior art date: 2005-12-22

Application number

DK06846727.3T

Other languages

English (en)

Inventor

Mehul Patel

Stephen Poole

Original Assignee

Health Prot Agency

Baxter Int

Baxter Healthcare Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-22

Filing date

2006-12-20

Publication date

2013-03-04

2006-12-20 Application filed by Health Prot Agency, Baxter Int, Baxter Healthcare Sa filed Critical Health Prot Agency

2013-03-04 Application granted granted Critical

2013-03-04 Publication of DK1977252T3 publication Critical patent/DK1977252T3/da

Links

230000004913 activation Effects 0.000 title 1
239000000356 contaminant Substances 0.000 title 1
239000002158 endotoxin Substances 0.000 title 1
229940127554 medical product Drugs 0.000 title 1
210000001616 monocyte Anatomy 0.000 title 1
230000001698 pyrogenic effect Effects 0.000 title 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/5055—Cells of the immune system involving macrophages
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5412—IL-6
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7095—Inflammation

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Cell Biology (AREA)
Medicinal Chemistry (AREA)
General Physics & Mathematics (AREA)
Biotechnology (AREA)
Food Science & Technology (AREA)
Pathology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Tropical Medicine & Parasitology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Physiology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK06846727.3T 2005-12-22 2006-12-20 Forbedret monocytaktiveringsprøve med bedre evne til påvisning af pyrogene ikke-endotoxin-kontaminanter i medicinske produkter DK1977252T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US75297005P	2005-12-22	2005-12-22
PCT/US2006/062424 WO2007076411A1 (en)	2005-12-22	2006-12-20	Improved monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products

Publications (1)

Publication Number	Publication Date
DK1977252T3 true DK1977252T3 (da)	2013-03-04

Family

ID=37913652

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK06846727.3T DK1977252T3 (da)	2005-12-22	2006-12-20	Forbedret monocytaktiveringsprøve med bedre evne til påvisning af pyrogene ikke-endotoxin-kontaminanter i medicinske produkter
DK11003878.3T DK2360479T3 (da)	2005-12-22	2006-12-20	Forbedret monocytaktiveringsprøve til påvisning af pyrogene ikke-endotoxin-forureninger i medicinske produkter

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK11003878.3T DK2360479T3 (da)	2005-12-22	2006-12-20	Forbedret monocytaktiveringsprøve til påvisning af pyrogene ikke-endotoxin-forureninger i medicinske produkter

Country Status (16)

Country	Link
US (5)	US7736863B2 (da)
EP (2)	EP1977252B1 (da)
JP (1)	JP4686611B2 (da)
KR (1)	KR101352222B1 (da)
CN (2)	CN103901208B (da)
AU (1)	AU2006330562B2 (da)
BR (1)	BRPI0620434A2 (da)
CA (1)	CA2633523A1 (da)
DK (2)	DK1977252T3 (da)
ES (2)	ES2400965T3 (da)
HK (1)	HK1199753A1 (da)
MX (1)	MX2008008138A (da)
PL (2)	PL2360479T3 (da)
PT (2)	PT2360479E (da)
SG (1)	SG179468A1 (da)
WO (1)	WO2007076411A1 (da)

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KR101352222B1 (ko) *	2005-12-22	2014-02-04	백스터 인터내셔널 인코포레이티드	의료용 제품에서 비-내독소 발열성 오염물을 보다 잘검출할 수 있는 개선된 단핵구 활성화 시험
DE102006031483B4 (de) *	2006-07-07	2009-12-24	Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.	Zellulärer Pyrogentest
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WO2009063307A2 (en) *	2007-11-14	2009-05-22	Bio-Technology General (Israel) Ltd.	Inflammatory activity detection method using il-6
MX340916B (es)	2008-01-18	2016-07-29	President And Fellows Of Harvard College *	Metodos para detectar señales de identificacion de enfermedad o condiciones en fluidos corporales.
JP5438751B2 (ja)	2008-03-20	2014-03-12	バクスター・インターナショナル・インコーポレイテッド	酵素消化による微生物生成物の破壊
US20090239819A1 (en) *	2008-03-20	2009-09-24	Run Wang	Peritoneal dialysis solution test method
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EP3309556B1 (en) *	2009-06-25	2020-04-08	Prometheus Biosciences, Inc.	Methods for diagnosing irritable bowel syndrome
US20130203624A1 (en)	2010-07-23	2013-08-08	President And Fellows Of Harvard College	Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions
AU2011280997A1 (en)	2010-07-23	2013-02-28	President And Fellows Of Harvard College	Methods of detecting autoimmune or immune-related diseases or conditions
SG194005A1 (en)	2011-04-08	2013-11-29	Roquette Freres	Methods for detecting contaminants in solutions containing glucose polymers
FR2978774B1 (fr) *	2011-08-02	2015-02-20	Roquette Freres	Methodes de detection des contaminants des circuits de production de polymeres de glucose
US20140295477A1 (en) *	2011-09-01	2014-10-02	Fresenius Medical Care Holdings, Inc	Kit For Sampling And Detection Of Endotoxin In Aqueous Solution
CA2845674C (en)	2011-12-21	2018-01-16	Grifols, S.A.	Identification of atypical antibodies in human blood and blood products
JP6244356B2 (ja) *	2012-05-29	2017-12-06	ロケットフレールＲｏｑｕｅｔｔｅＦｒｅｒｅｓ	グルコースポリマーおよびグルコースポリマー加水分解物の製造回路の除染方法
WO2014052593A1 (en) *	2012-09-26	2014-04-03	Cook Biotech Incorporated	Medical device design, manufacture and testing systems
EP3119813B1 (fr)	2014-03-21	2023-01-04	Roquette Frères	Procede optimise de decontamination de production de polymeres de glucose et d'hydrolysats de polymeres de glucose
BR112017020149A8 (pt)	2015-03-27	2023-05-02	Regeneron Pharma	Derivados de maitansinoide, conjugados dos mesmos e métodos de uso
FR3037063B1 (fr)	2015-06-04	2017-05-19	Roquette Freres	Procede optimise de decontamination de l'amidon utilise comme matiere premiere pour l'obtention de polymeres de glucose destines a la dialyse peritoneale
EP3171170A1 (en) *	2015-11-17	2017-05-24	Lionex GmbH	Device for use in elispot
ES3046537T3 (en)	2016-11-08	2025-12-02	Regeneron Pharma	Steroids and protein-conjugates thereof
WO2021100828A1 (ja) *	2019-11-19	2021-05-27	マイキャン・テクノロジーズ株式会社	ヒト不死化ミエロイド系細胞を使用したｉｎｖｉｔｒｏにおける物質の安全性評価方法
EP4006546A1 (en) *	2020-11-30	2022-06-01	Medizinische Hochschule Hannover	Application of stem-cell derived monocytes in a monocyte activation test (mat) for the assessment of pyrogenicity and inflammatory potential
CA3266655A1 (en) *	2022-09-06	2024-03-14	Mat Research B.V.	IMPROVED MONOCYTE ACTIVATION TEST
JPWO2024204725A1 (da) *	2023-03-30	2024-10-03

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2006
- 2006-12-20 KR KR1020087017829A patent/KR101352222B1/ko active Active
- 2006-12-20 PT PT110038783T patent/PT2360479E/pt unknown
- 2006-12-20 PL PL11003878T patent/PL2360479T3/pl unknown
- 2006-12-20 US US11/613,866 patent/US7736863B2/en active Active
- 2006-12-20 EP EP06846727A patent/EP1977252B1/en active Active
- 2006-12-20 CN CN201310252724.0A patent/CN103901208B/zh not_active Expired - Fee Related
- 2006-12-20 CN CN2006800488729A patent/CN101346630B/zh not_active Expired - Fee Related
- 2006-12-20 DK DK06846727.3T patent/DK1977252T3/da active
- 2006-12-20 JP JP2008547757A patent/JP4686611B2/ja not_active Expired - Fee Related
- 2006-12-20 EP EP11003878.3A patent/EP2360479B1/en active Active
- 2006-12-20 AU AU2006330562A patent/AU2006330562B2/en not_active Ceased
- 2006-12-20 PT PT68467273T patent/PT1977252E/pt unknown
- 2006-12-20 WO PCT/US2006/062424 patent/WO2007076411A1/en not_active Ceased
- 2006-12-20 DK DK11003878.3T patent/DK2360479T3/da active
- 2006-12-20 CA CA002633523A patent/CA2633523A1/en not_active Abandoned
- 2006-12-20 MX MX2008008138A patent/MX2008008138A/es active IP Right Grant
- 2006-12-20 PL PL06846727T patent/PL1977252T3/pl unknown
- 2006-12-20 BR BRPI0620434-1A patent/BRPI0620434A2/pt not_active IP Right Cessation
- 2006-12-20 ES ES06846727T patent/ES2400965T3/es active Active
- 2006-12-20 SG SG2012017133A patent/SG179468A1/en unknown
- 2006-12-20 ES ES11003878.3T patent/ES2477588T3/es active Active
2010
- 2010-04-26 US US12/767,537 patent/US8053200B2/en active Active
- 2010-04-26 US US12/767,514 patent/US8058021B2/en active Active
2011
- 2011-11-10 US US13/293,868 patent/US9023647B2/en active Active
2015
- 2015-01-02 HK HK15100025.2A patent/HK1199753A1/xx unknown
- 2015-04-06 US US14/679,651 patent/US9671411B2/en active Active

Also Published As

Publication number	Publication date
PL2360479T3 (pl)	2014-09-30
CN101346630A (zh)	2009-01-14
US20150285819A1 (en)	2015-10-08
JP2009521690A (ja)	2009-06-04
PT1977252E (pt)	2013-01-28
BRPI0620434A2 (pt)	2011-11-16
KR20080080400A (ko)	2008-09-03
US8058021B2 (en)	2011-11-15
US9671411B2 (en)	2017-06-06
HK1161638A1 (en)	2012-07-27
US20070184496A1 (en)	2007-08-09
AU2006330562A1 (en)	2007-07-05
CN101346630B (zh)	2013-07-17
EP2360479A3 (en)	2011-08-31
US20120058559A1 (en)	2012-03-08
CN103901208A (zh)	2014-07-02
PT2360479E (pt)	2014-07-10
PL1977252T3 (pl)	2013-07-31
EP2360479A2 (en)	2011-08-24
ES2400965T3 (es)	2013-04-15
US8053200B2 (en)	2011-11-08
ES2477588T3 (es)	2014-07-17
CN103901208B (zh)	2016-08-24
MX2008008138A (es)	2008-11-28
EP2360479B1 (en)	2014-04-02
HK1119243A1 (en)	2009-02-27
DK2360479T3 (da)	2014-04-07
SG179468A1 (en)	2012-04-27
ES2400965T8 (es)	2013-06-04
US9023647B2 (en)	2015-05-05
EP1977252B1 (en)	2012-12-05
KR101352222B1 (ko)	2014-02-04
EP1977252A1 (en)	2008-10-08
US20100203557A1 (en)	2010-08-12
HK1199753A1 (en)	2015-07-17
JP4686611B2 (ja)	2011-05-25
WO2007076411A1 (en)	2007-07-05
US7736863B2 (en)	2010-06-15
CA2633523A1 (en)	2007-07-05
US20100203551A1 (en)	2010-08-12
AU2006330562B2 (en)	2013-05-02

Publication	Publication Date	Title
DK1977252T3 (da)	2013-03-04	Forbedret monocytaktiveringsprøve med bedre evne til påvisning af pyrogene ikke-endotoxin-kontaminanter i medicinske produkter
EP2079489A4 (en)	2013-01-02	ABSORBENT ARTICLE WITH ABSORPTION STRUCTURE
FI20050768L (fi)	2007-01-20	Terveydenseurantalaite ja laitemoduuli
EP2145171A4 (en)	2012-04-04	COMPACT AND COST-EFFECTIVE PARTICLE SENSOR
EP2038775A4 (en)	2010-01-20	VISUAL AND MULTI-DIMENSIONAL SEARCH
BRPI0913640A2 (pt)	2016-08-16	substâncias policrômicas e seus usos
DE602006018919D1 (de)	2011-01-27	Fahrzeug und spurerkennungsvorrichtung
BRPI0921862A2 (pt)	2015-12-29	inibidores de raf e seus usos
BRPI0906498A2 (pt)	2015-07-14	Anticorpo ron e seus usos
BRPI0816165A2 (pt)	2015-02-24	Dispositivo de citaferese seletiva e seus métodos relacionados
DE602007010480D1 (de)	2010-12-23	Blutsensor und diesen enthaltendes blutuntersuchungsinstrument
DK2231091T3 (da)	2013-01-28	Absorber og absorberende engangsartikel
BRPI0910746A2 (pt)	2016-07-26	reticuladores e seus usos
BRPI0814963A2 (pt)	2015-02-03	Pró-fármacos de dipeptóides e seu uso
EP2260926A4 (en)	2012-07-25	MEMBRANE MODULE AND MEMBRANE ASSASSET
DE602007004270D1 (de)	2010-03-04	Fremdobjekterkennungsvorrichtung
BRPI0918551A2 (pt)	2015-12-08	dispositivo de capacitância, e, circuito de ressonância
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