DK1992618T3 - Polycyklisk cinnamidderivat - Google Patents
Polycyklisk cinnamidderivatInfo
- Publication number
- DK1992618T3 DK1992618T3 DK07738023.6T DK07738023T DK1992618T3 DK 1992618 T3 DK1992618 T3 DK 1992618T3 DK 07738023 T DK07738023 T DK 07738023T DK 1992618 T3 DK1992618 T3 DK 1992618T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- substituted
- polycyclic
- cinnamide derivative
- alkyl group
- Prior art date
Links
- APEJMQOBVMLION-VOTSOKGWSA-N trans-cinnamamide Chemical class NC(=O)\C=C\C1=CC=CC=C1 APEJMQOBVMLION-VOTSOKGWSA-N 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000002883 imidazolyl group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78051706P | 2006-03-09 | 2006-03-09 | |
| JP2006063562 | 2006-03-09 | ||
| US86170206P | 2006-11-30 | 2006-11-30 | |
| JP2006322728 | 2006-11-30 | ||
| PCT/JP2007/054532 WO2007102580A1 (ja) | 2006-03-09 | 2007-03-08 | 多環式シンナミド誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1992618T3 true DK1992618T3 (da) | 2012-04-10 |
Family
ID=43217093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07738023.6T DK1992618T3 (da) | 2006-03-09 | 2007-03-08 | Polycyklisk cinnamidderivat |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US7713993B2 (da) |
| JP (1) | JP5210152B2 (da) |
| CN (1) | CN101400657B (da) |
| AT (1) | ATE541836T1 (da) |
| BR (1) | BRPI0708303A2 (da) |
| DK (1) | DK1992618T3 (da) |
| ES (1) | ES2377740T3 (da) |
| ME (1) | MEP10708A (da) |
| MY (1) | MY148703A (da) |
| NZ (1) | NZ571121A (da) |
| PE (1) | PE20080140A1 (da) |
| PT (1) | PT1992618E (da) |
| RS (1) | RS52240B (da) |
| SA (1) | SA07280094B1 (da) |
| SI (1) | SI1992618T1 (da) |
| TN (1) | TNSN08343A1 (da) |
| TW (1) | TWI378091B (da) |
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| BRPI0511504A (pt) * | 2004-05-26 | 2008-01-22 | Eisai R&D Man Co Ltd | composto ou um sal farmaceuticamente aceitável do mesmo, e, agente preventivo ou terapêutico para uma doença resultante de beta-amilóides |
| ATE458729T1 (de) * | 2004-10-26 | 2010-03-15 | Eisai R&D Man Co Ltd | Amorphe form einer zimtsäureamidverbindung |
| ES2400772T3 (es) * | 2005-06-07 | 2013-04-12 | Ramot At Tel Aviv University Ltd. | Sales novedosas de fármacos psicotrópicos conjugados y procedimientos para la preparación de las mismas |
| AU2006316005A1 (en) * | 2005-11-18 | 2007-05-24 | Eisai R & D Management Co., Ltd. | Process for production of cinnamamide derivative |
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| MY144960A (en) * | 2005-11-24 | 2011-11-30 | Eisai R&D Man Co Ltd | Morpholine type cinnamide compound |
| TWI378091B (en) * | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
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| ES2529648T3 (es) * | 2007-08-31 | 2015-02-24 | Eisai R&D Management Co., Ltd. | Compuesto policíclico |
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| WO2012038963A1 (en) | 2010-09-22 | 2012-03-29 | Ramot At Tel-Aviv University Ltd. | An acid addition salt of a nortriptyline-gaba conjugate and a process of preparing same |
| WO2012131539A1 (en) | 2011-03-31 | 2012-10-04 | Pfizer Inc. | Novel bicyclic pyridinones |
| US9199975B2 (en) | 2011-09-30 | 2015-12-01 | Asana Biosciences, Llc | Biaryl imidazole derivatives for regulating CYP17 |
| HUE028858T2 (hu) | 2011-10-03 | 2017-01-30 | Euroscreen Sa | Új királis N-acil-5,6,7,(8-szubsztituált)-tetrahidro-[1,2,4]triazolo[4,3-A]pirazinok mint szelektív NK-3 receptor antagonisták, gyógyászati készítmény és eljárások NK-3 receptor által közvetített rendellenességek során történõ alkalmazásra |
| EP2687528A1 (en) * | 2012-07-17 | 2014-01-22 | Ares Trading S.A. | Fused triazole derivatives as gamma secretase modulators |
| UA110688C2 (uk) | 2012-09-21 | 2016-01-25 | Пфайзер Інк. | Біциклічні піридинони |
| ES2711095T3 (es) | 2014-09-25 | 2019-04-30 | Ogeda Sa | Nueva síntesis quiral de N-acil-(3-sustituida)-(8-sustituida)-5,6-dihidro-[1,2,4]triazolo [4,3-a] pirazinas |
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| TWI370130B (en) | 2005-11-24 | 2012-08-11 | Eisai R&D Man Co Ltd | Two cyclic cinnamide compound |
| MY144960A (en) | 2005-11-24 | 2011-11-30 | Eisai R&D Man Co Ltd | Morpholine type cinnamide compound |
| TWI378091B (en) | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
| PL1992618T3 (pl) | 2006-03-09 | 2012-06-29 | Eisai R&D Man Co Ltd | Policykliczna pochodna cynamidowa |
| JP2008004571A (ja) | 2006-06-20 | 2008-01-10 | Matsushita Electric Ind Co Ltd | ポリシリコンヒューズ及びその製造方法 |
| US7737141B2 (en) | 2006-07-28 | 2010-06-15 | Eisai R&D Management Co., Ltd. | Prodrug of cinnamide compound |
| JP2010518080A (ja) | 2007-02-08 | 2010-05-27 | メルク・シャープ・エンド・ドーム・コーポレイション | 治療薬 |
| WO2008137102A2 (en) | 2007-05-04 | 2008-11-13 | Torreypines Therapeutics, Inc. | Methods of modulating amyloid beta and compounds useful therefor |
| CA2686589A1 (en) | 2007-05-07 | 2008-11-13 | Schering Corporation | Gamma secretase modulators |
| AU2008250436B2 (en) | 2007-05-11 | 2013-03-28 | F. Hoffmann-La Roche Ag | Hetarylanilines as modulators for amyloid beta |
| WO2008156580A1 (en) | 2007-06-13 | 2008-12-24 | Merck & Co., Inc. | Triazole derivatives for treating alzheimer's disease and related conditions |
| US20110009392A1 (en) | 2007-08-06 | 2011-01-13 | Schering Corporation | Gamma secretase modulators |
-
2007
- 2007-03-06 TW TW096107693A patent/TWI378091B/zh not_active IP Right Cessation
- 2007-03-07 SA SA07280094A patent/SA07280094B1/ar unknown
- 2007-03-08 US US11/715,440 patent/US7713993B2/en not_active Expired - Fee Related
- 2007-03-08 PT PT07738023T patent/PT1992618E/pt unknown
- 2007-03-08 NZ NZ571121A patent/NZ571121A/en not_active IP Right Cessation
- 2007-03-08 BR BRPI0708303-3A patent/BRPI0708303A2/pt not_active IP Right Cessation
- 2007-03-08 MY MYPI20083255A patent/MY148703A/en unknown
- 2007-03-08 AT AT07738023T patent/ATE541836T1/de active
- 2007-03-08 SI SI200730897T patent/SI1992618T1/sl unknown
- 2007-03-08 RS RS20120088A patent/RS52240B/sr unknown
- 2007-03-08 ES ES07738023T patent/ES2377740T3/es active Active
- 2007-03-08 CN CN2007800083820A patent/CN101400657B/zh not_active Expired - Fee Related
- 2007-03-08 JP JP2008503909A patent/JP5210152B2/ja not_active Expired - Fee Related
- 2007-03-08 DK DK07738023.6T patent/DK1992618T3/da active
- 2007-03-08 PE PE2007000251A patent/PE20080140A1/es not_active Application Discontinuation
- 2007-03-08 ME MEP-107/08A patent/MEP10708A/xx unknown
-
2008
- 2008-08-29 TN TNP2008000343A patent/TNSN08343A1/en unknown
-
2010
- 2010-03-11 US US12/721,952 patent/US7897632B2/en not_active Expired - Fee Related
-
2011
- 2011-01-12 US US13/005,064 patent/US7973033B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SI1992618T1 (sl) | 2012-05-31 |
| CN101400657B (zh) | 2012-05-30 |
| US20070219181A1 (en) | 2007-09-20 |
| RS52240B (sr) | 2012-10-31 |
| JPWO2007102580A1 (ja) | 2009-07-23 |
| ES2377740T3 (es) | 2012-03-30 |
| US7897632B2 (en) | 2011-03-01 |
| PE20080140A1 (es) | 2008-03-29 |
| US7973033B2 (en) | 2011-07-05 |
| TW200806634A (en) | 2008-02-01 |
| MY148703A (en) | 2013-05-31 |
| ATE541836T1 (de) | 2012-02-15 |
| PT1992618E (pt) | 2012-02-03 |
| SA07280094B1 (ar) | 2010-04-04 |
| NZ571121A (en) | 2011-06-30 |
| BRPI0708303A2 (pt) | 2011-05-24 |
| US7713993B2 (en) | 2010-05-11 |
| TWI378091B (en) | 2012-12-01 |
| MEP10708A (en) | 2010-06-10 |
| JP5210152B2 (ja) | 2013-06-12 |
| US20100168095A1 (en) | 2010-07-01 |
| TNSN08343A1 (en) | 2009-12-29 |
| US20110112138A1 (en) | 2011-05-12 |
| CN101400657A (zh) | 2009-04-01 |
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