DK1996571T3 - Tetracycliske steroidderivater, der kan anvendes som progesteronreceptormodulatorer - Google Patents

Tetracycliske steroidderivater, der kan anvendes som progesteronreceptormodulatorer

Info

Publication number: DK1996571T3
Authority: DK; Denmark
Prior art keywords: steroid derivatives; receptor modulators; progesterone receptor; tetracyclic steroid; tetracyclic
Prior art date: 2006-02-17

Application number

DK07757092.7T

Other languages

English (en)

Inventor

Ningyi Chen

Nareshkumar F Jain

Zhihua Sui

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-17

Filing date

2007-02-16

Publication date

2011-02-07

2007-02-16 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2011-02-07 Application granted granted Critical

2011-02-07 Publication of DK1996571T3 publication Critical patent/DK1996571T3/da

Links

150000003431 steroids Chemical class 0.000 title abstract 2
239000002379 progesterone receptor modulator Substances 0.000 title 1
229940095745 sex hormone and modulator of the genital system progesterone receptor modulator Drugs 0.000 title 1
RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 2
108090000079 Glucocorticoid Receptors Proteins 0.000 abstract 1
102100033417 Glucocorticoid receptor Human genes 0.000 abstract 1
102100025803 Progesterone receptor Human genes 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
229960003387 progesterone Drugs 0.000 abstract 1
239000000186 progesterone Substances 0.000 abstract 1
108090000468 progesterone receptors Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Hematology (AREA)
Pregnancy & Childbirth (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

DK07757092.7T 2006-02-17 2007-02-16 Tetracycliske steroidderivater, der kan anvendes som progesteronreceptormodulatorer DK1996571T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US77434806P	2006-02-17	2006-02-17
PCT/US2007/062280 WO2007098384A2 (en)	2006-02-17	2007-02-16	Tetracyclic steroid derivatives useful as progesterone receptor modulators

Publications (1)

Publication Number	Publication Date
DK1996571T3 true DK1996571T3 (da)	2011-02-07

Family

ID=38290140

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07757092.7T DK1996571T3 (da)	2006-02-17	2007-02-16	Tetracycliske steroidderivater, der kan anvendes som progesteronreceptormodulatorer

Country Status (15)

Country	Link
US (1)	US7390831B2 (da)
EP (1)	EP1996571B1 (da)
JP (1)	JP5230451B2 (da)
CN (1)	CN101421261B (da)
AT (1)	ATE485286T1 (da)
AU (1)	AU2007217097B2 (da)
CA (1)	CA2642763A1 (da)
CY (1)	CY1111110T1 (da)
DE (1)	DE602007009945D1 (da)
DK (1)	DK1996571T3 (da)
ES (1)	ES2353133T3 (da)
PL (1)	PL1996571T3 (da)
PT (1)	PT1996571E (da)
SI (1)	SI1996571T1 (da)
WO (1)	WO2007098384A2 (da)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2077752B1 (da) *	1970-02-11	1973-03-16	Roussel Uclaf

2007
- 2007-02-16 EP EP07757092A patent/EP1996571B1/en not_active Not-in-force
- 2007-02-16 AT AT07757092T patent/ATE485286T1/de active
- 2007-02-16 CN CN2007800135609A patent/CN101421261B/zh not_active Expired - Fee Related
- 2007-02-16 PT PT07757092T patent/PT1996571E/pt unknown
- 2007-02-16 JP JP2008555507A patent/JP5230451B2/ja not_active Expired - Fee Related
- 2007-02-16 AU AU2007217097A patent/AU2007217097B2/en not_active Expired - Fee Related
- 2007-02-16 DK DK07757092.7T patent/DK1996571T3/da active
- 2007-02-16 CA CA002642763A patent/CA2642763A1/en not_active Abandoned
- 2007-02-16 DE DE602007009945T patent/DE602007009945D1/de active Active
- 2007-02-16 SI SI200730467T patent/SI1996571T1/sl unknown
- 2007-02-16 ES ES07757092T patent/ES2353133T3/es active Active
- 2007-02-16 PL PL07757092T patent/PL1996571T3/pl unknown
- 2007-02-16 WO PCT/US2007/062280 patent/WO2007098384A2/en not_active Ceased
- 2007-02-16 US US11/675,665 patent/US7390831B2/en not_active Expired - Fee Related
2011
- 2011-01-14 CY CY20111100046T patent/CY1111110T1/el unknown

Also Published As

Publication number	Publication date
SI1996571T1 (sl)	2011-02-28
ES2353133T3 (es)	2011-02-25
AU2007217097B2 (en)	2012-12-06
CN101421261A (zh)	2009-04-29
DE602007009945D1 (de)	2010-12-02
CY1111110T1 (el)	2015-06-11
US20070197634A1 (en)	2007-08-23
US7390831B2 (en)	2008-06-24
PL1996571T3 (pl)	2011-04-29
JP2009527492A (ja)	2009-07-30
JP5230451B2 (ja)	2013-07-10
EP1996571A2 (en)	2008-12-03
WO2007098384A2 (en)	2007-08-30
HK1126475A1 (en)	2009-09-04
ATE485286T1 (de)	2010-11-15
WO2007098384A3 (en)	2007-10-04
PT1996571E (pt)	2010-12-07
AU2007217097A1 (en)	2007-08-30
CN101421261B (zh)	2013-01-23
CA2642763A1 (en)	2007-08-30
EP1996571B1 (en)	2010-10-20

Publication	Publication Date	Title
DK1989218T3 (da)	2010-04-26	17-phosphor-steroidderivater, der er anvendelige som progesteronreceptormodulatorer
WO2010054158A3 (en)	2010-08-19	Steroid modulators of glucocorticoid receptor
TW200621725A (en)	2006-07-01	Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
ECSP088648A (es)	2008-08-29	Nuevos bencimidazoles 2-sustituidos como moduladores de receptor de androgeno selectivos (sarms)
WO2007098381A3 (en)	2008-01-03	11-phosphorous steroid derivatives useful as progesterone receptor modulators
TW200621235A (en)	2006-07-01	Novel heterocycle derivatives useful as selective androgen receptor modulators (sarms)
PH12014501078A1 (en)	2014-07-28	Pharmaceutical compositions and methods of use of 4-pregenen-11�-17-21-triol-3,20-dione derivatives
TW200606146A (en)	2006-02-16	Novel indole derivatives as selective androgen receptor modulators (SARMS)
EA200970085A1 (ru)	2009-06-30	Замещённые n-фенилметил-5-оксопролин-2-амиды в качестве антагонистов р2х7-рецептора и способы их применения
EA201190236A1 (ru)	2012-04-30	Новые производные стероидных соединений [3,2-c]пиразолов с глюкокортикоидной активностью
TW200624424A (en)	2006-07-16	Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
TW200604171A (en)	2006-02-01	Novel indole derivatives as selective androgen receptor modulators (SARMs)
TW200604170A (en)	2006-02-01	Novel indole derivatives as selective androgen receptor modulators (SARMs)
ATE473741T1 (de)	2010-07-15	Neue imidazolopyrazolderivate als selektive androgen-rezeptor-modulatoren
WO2008109719A3 (en)	2008-11-06	Steroids derivatives as selective progesterone receptor modulators
WO2009140225A3 (en)	2010-03-04	Anti-inflammatory and immunosuppresive glucocorticoid steroids
ATE485286T1 (de)	2010-11-15	Tetracyclische steroidderivate als progesteron- rezeptormodulatoren
WO2007098388A3 (en)	2007-12-06	Oxa-steroids derivatives as selective progesterone receptor modulators
DK1812417T3 (da)	2009-02-16	Nye 2H-chromenderivater som selektive östrogenreceptormodulatorer