DK200100314A - Implantat og implantatoverflademodificeringsproces - Google Patents

Implantat og implantatoverflademodificeringsproces Download PDF

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Publication number
DK200100314A
DK200100314A DK200100314A DKPA200100314A DK200100314A DK 200100314 A DK200100314 A DK 200100314A DK 200100314 A DK200100314 A DK 200100314A DK PA200100314 A DKPA200100314 A DK PA200100314A DK 200100314 A DK200100314 A DK 200100314A
Authority
DK
Denmark
Prior art keywords
implant
tissue
base body
outer zone
surface modification
Prior art date
Application number
DK200100314A
Other languages
English (en)
Inventor
Christensen John
Original Assignee
Danfoss As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DK200100314A priority Critical patent/DK174876B1/da
Application filed by Danfoss As filed Critical Danfoss As
Priority to US10/469,012 priority patent/US7156851B2/en
Priority to AT02711785T priority patent/ATE272413T1/de
Priority to ES02711785T priority patent/ES2225772T3/es
Priority to EP02711785A priority patent/EP1363683B1/en
Priority to PCT/DK2002/000099 priority patent/WO2002068007A1/en
Priority to DE60200884T priority patent/DE60200884T2/de
Priority to US10/469,017 priority patent/US7150818B2/en
Priority to ES02700187T priority patent/ES2236479T3/es
Priority to DE60202592T priority patent/DE60202592T2/de
Priority to AT02700187T priority patent/ATE286996T1/de
Priority to PCT/DK2002/000127 priority patent/WO2002068729A1/en
Priority to EP02700187A priority patent/EP1364079B1/en
Publication of DK200100314A publication Critical patent/DK200100314A/da
Application granted granted Critical
Publication of DK174876B1 publication Critical patent/DK174876B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D3/00—Electroplating: Baths therefor
    • C25D3/66—Electroplating: Baths therefor from melts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/10—Inorganic materials
    • A61L29/106—Inorganic materials other than carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrochemistry (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Mechanical Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Electroplating Methods And Accessories (AREA)
  • Electrolytic Production Of Metals (AREA)
  • Dental Prosthetics (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Primary Cells (AREA)

Description

PATENTKRAV 1. Implantat, særligt et hofteimplantat, et tandimplantat, en knogleskrue, en fikseringsstift eller et fikseringssøm (pin-fixation) , omfattende et metallisk grundlegeme (1), hvilket implantat har en overflade, som er modificeret med et materiale, der indholder et vævsvenligt metal, såsom tantal eller niob, til dannelse af en overflademodificering (4) kendetegnet ved, at i det mindste det vævsvenlige metal er legeret med overfladen og udgør en ensartet, diffusionstæt yderzone (2) på legemet (1), hvilken yderzone (2) har større duktilitet end det metalliske grundlegeme (1). 2. Implantat ifølge krav 1, kendetegnet ved, at det metalliske grundlegeme (1) består af en CoCrMo-legering. 3. Implantat ifølge krav 1 eller 2, kendetegnet ved, at grundlegemet er modificeret ved en saltsmelteproces til en tykkelse af yderzonen (2) på ca. 2-14 pm, fortrinsvis mere end 5 pm og mindre end 12 pm, og særligt 8-10 pm. 4. Implantat ifølge krav 1 eller 2, kendetegnet ved, at grundlegemet (1) er modificeret ved en CVD-proces til en tykkelse af yderzonen (2) på ca. 10-35 pm, fortrinsvis mere end 12 pm og mindre end 25 pm, særligt 12-17 pm. 5. Implantat ifølge et af de foregående krav, kendetegnet ved, at det vævsvenlige metal består af tantal. 6. Implantat ifølge et af de foregående krav, kendetegnet ved, at det vævsvenlige metal består af a-tantal. 7. Implantat ifølge et af de foregående krav, kendetegnet ved, at implantatet har tryk- spændinger i overfladen. 8. Implantat ifølge et af de foregående krav, kendetegnet ved, at overflademodificeringen (4) desuden omfatter en legeringszone (3) indlegeret i overfladen af grundlegemet (1), idet der i legeringszonen (3) er gradvist stigende koncentration af modificeringsmateriale i retning mod overfladen af yderzonen (2), mens koncentrationen af grundlegemets legering gradvist aftager i retning mod overfladen af yderzonen (2). 9. Implantat ifølge et af de foregående krav, kendetegnet ved, at implantatet har styrkemæssige egenskaber, der i det væsentlige svarer til de styrkemæssige egenskaber af den knogle implantatet indsættes i. 10. Implantat ifølge et af de foregående krav, kendetegnet ved, at implantatet er en fikseringsstift eller et fikseringssøm (pin-fixation) med en diameter under 10 mm. 11. Implantat ifølge et af kravene 1-10, kendetegnet ved, at overfladen af implantatet yderligere er modificeret med et indvækstfremmende stof, såsom calcium eller hydroxyapatit. 12. Implantatoverflademodificeringsproces, der modificerer en overflade af et implantat, særligt et hofteimplantat, et tandimplantat, en knogleskrue eller lignende, omfattende et metallisk grundlegeme (1), hvilket implantat modificeres med et materiale, der indeholder et vævsvenligt metal, såsom tantal eller niob, kendetegnet ved, at modificeringen omfatter en CVD- eller saltsmelteproces med det vævsvenlige materiale, som ved processen indlegeres i overfladen af legemet (1), hvorved overfladen får en legeringszone (3), idet det tillegerede materiale diffunderer op til nogle mikrometer ind legemet (1) , og tilførsel af materiale fortsættes indtil der er dannet en yderzone (2) med en ensartet, diffusionstæt overflade af i det væsentlige rent vævsvenligt metal, idet legeringszonen (3) går gradvist over i den diffusionstætte yderzone (2).
DK200100314A 2001-02-26 2001-02-26 Implantat og implantatoverflademodificeringsproces DK174876B1 (da)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DK200100314A DK174876B1 (da) 2001-02-26 2001-02-26 Implantat og implantatoverflademodificeringsproces
AT02711785T ATE272413T1 (de) 2001-02-26 2002-02-12 Implantat und verfahren zur veränderung von implantatoberflächen
ES02711785T ES2225772T3 (es) 2001-02-26 2002-02-12 Implante y procedimiento para modificar la superficie de un implante.
EP02711785A EP1363683B1 (en) 2001-02-26 2002-02-12 Implant and process of modifying an implant surface
PCT/DK2002/000099 WO2002068007A1 (en) 2001-02-26 2002-02-12 Implant and process of modifying an implant surface
DE60200884T DE60200884T2 (de) 2001-02-26 2002-02-12 Implantat und verfahren zur veränderung von implantatoberflächen
US10/469,012 US7156851B2 (en) 2001-02-26 2002-02-12 Implant and process of modifying an implant surface
US10/469,017 US7150818B2 (en) 2001-02-26 2002-02-26 Process for electrochemical deposition of tantalum and an article having a surface modification
ES02700187T ES2236479T3 (es) 2001-02-26 2002-02-26 Un procedimiento para la deposicion electroquimica de tantalio.
DE60202592T DE60202592T2 (de) 2001-02-26 2002-02-26 Verfahren zur elektrochemischen abscheidung von tantal
AT02700187T ATE286996T1 (de) 2001-02-26 2002-02-26 Verfahren zur elektrochemischen abscheidung von tantal
PCT/DK2002/000127 WO2002068729A1 (en) 2001-02-26 2002-02-26 A process for electrochemical deposition of tantalum and an article having a surface modification
EP02700187A EP1364079B1 (en) 2001-02-26 2002-02-26 A process for electrochemical deposition of tantalum

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK200100314 2001-02-26
DK200100314A DK174876B1 (da) 2001-02-26 2001-02-26 Implantat og implantatoverflademodificeringsproces

Publications (2)

Publication Number Publication Date
DK200100314A true DK200100314A (da) 2002-08-27
DK174876B1 DK174876B1 (da) 2004-01-12

Family

ID=8160304

Family Applications (1)

Application Number Title Priority Date Filing Date
DK200100314A DK174876B1 (da) 2001-02-26 2001-02-26 Implantat og implantatoverflademodificeringsproces

Country Status (7)

Country Link
US (2) US7156851B2 (da)
EP (2) EP1363683B1 (da)
AT (2) ATE272413T1 (da)
DE (2) DE60200884T2 (da)
DK (1) DK174876B1 (da)
ES (2) ES2225772T3 (da)
WO (2) WO2002068007A1 (da)

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DE112005002435B4 (de) * 2004-10-01 2014-01-02 Kyoto University Salzschmelzebad, Abscheidung erhalten unter Verwendung des Salzschmelzebades, Herstellungsverfahren für ein Metallprodukt und Metallprodukt
ITTO20040692A1 (it) * 2004-10-08 2005-01-08 Torino Politecnico Dispositivi prostetici medicali biocompatibili a base di leghe di cobalto e procedimento per la loro preparazione
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Also Published As

Publication number Publication date
DE60202592D1 (de) 2005-02-17
EP1363683B1 (en) 2004-08-04
DE60202592T2 (de) 2005-12-29
WO2002068007A1 (en) 2002-09-06
US7156851B2 (en) 2007-01-02
ATE272413T1 (de) 2004-08-15
ES2236479T3 (es) 2005-07-16
WO2002068729A1 (en) 2002-09-06
ATE286996T1 (de) 2005-01-15
EP1364079B1 (en) 2005-01-12
DE60200884D1 (de) 2004-09-09
EP1364079A1 (en) 2003-11-26
DE60200884T2 (de) 2005-08-18
US20050258047A1 (en) 2005-11-24
EP1363683A1 (en) 2003-11-26
US20040068323A1 (en) 2004-04-08
DK174876B1 (da) 2004-01-12
US7150818B2 (en) 2006-12-19
ES2225772T3 (es) 2005-03-16

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