DK2022497T3 - Oral sammensætning, omfattende 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-](3-hydroxy-1,2-benzisoxazol-6- yl)methoxyphenylpropionsyre eller salt deraf - Google Patents

Oral sammensætning, omfattende 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-](3-hydroxy-1,2-benzisoxazol-6- yl)methoxyphenylpropionsyre eller salt deraf

Info

Publication number
DK2022497T3
DK2022497T3 DK07744105.3T DK07744105T DK2022497T3 DK 2022497 T3 DK2022497 T3 DK 2022497T3 DK 07744105 T DK07744105 T DK 07744105T DK 2022497 T3 DK2022497 T3 DK 2022497T3
Authority
DK
Denmark
Prior art keywords
benzisoxazol
hydroxybenzoyl
cyclopentyloxy
hydroxy
salt
Prior art date
Application number
DK07744105.3T
Other languages
English (en)
Inventor
Sahoe Kakuda
Tatsuhito Yahata
Masashi Kaneko
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of DK2022497T3 publication Critical patent/DK2022497T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK07744105.3T 2006-05-26 2007-05-25 Oral sammensætning, omfattende 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-](3-hydroxy-1,2-benzisoxazol-6- yl)methoxyphenylpropionsyre eller salt deraf DK2022497T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2006146315 2006-05-26
JP2006146257 2006-05-26
PCT/JP2007/060671 WO2007138997A1 (ja) 2006-05-26 2007-05-25 ３－｛５－［４－（シクロペンチルオキシ）－２－ヒドロキシベンゾイル］－２－［（３－ヒドロキシ－１，２－ベンズイソオキサゾール－６－イル）メトキシ］フェニル｝プロピオン酸またはその塩を含有する経口用組成物

Publications (1)

Publication Number Publication Date
DK2022497T3 true DK2022497T3 (da) 2014-05-19

Family

ID=38778517

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07744105.3T DK2022497T3 (da) 2006-05-26 2007-05-25 Oral sammensætning, omfattende 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-](3-hydroxy-1,2-benzisoxazol-6- yl)methoxyphenylpropionsyre eller salt deraf

Country Status (21)

Country Link
US (1) US8093289B2 (da)
EP (1) EP2022497B1 (da)
JP (1) JP5161077B2 (da)
KR (1) KR101394121B1 (da)
CN (1) CN101454003B (da)
AU (1) AU2007268772B2 (da)
BR (1) BRPI0709710A2 (da)
CA (1) CA2653023C (da)
CY (1) CY1115312T1 (da)
DK (1) DK2022497T3 (da)
ES (1) ES2463455T3 (da)
IL (1) IL195417A (da)
MX (1) MX2008015015A (da)
NO (1) NO20084634L (da)
NZ (1) NZ573035A (da)
PL (1) PL2022497T3 (da)
PT (1) PT2022497E (da)
RU (1) RU2436576C2 (da)
SI (1) SI2022497T1 (da)
WO (1) WO2007138997A1 (da)
ZA (1) ZA200810018B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2262477A1 (en) * 2008-03-04 2010-12-22 F. Hoffmann-La Roche AG Process for preparing concentrated aqueous micellar solutions
PL2258361T3 (pl) * 2008-03-27 2015-02-27 Toyama Chemical Co Ltd Zastosowanie pochodnej benzofenonu lub jej soli w kombinacji z inhibitorem TNFα i kompozycja farmaceutyczna zawierająca pochodną lub jej sól oraz inhibitor
WO2009131098A1 (ja) 2008-04-22 2009-10-29 富山化学工業株式会社 ベンゾフェノン誘導体またはその塩および免疫抑制剤を組み合わせて使用する方法ならびにこれらを含有する医薬組成物
EP2140861A1 (en) 2008-06-30 2010-01-06 Abbott GmbH & Co. KG Pharmaceutical dosage form comprising polymeric carrier composition
JP2015533134A (ja) * 2012-10-09 2015-11-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 錠剤の機械的安定性に適切な少なくとも１種の水和物形成活性物質及び／又はアジュバントを含有する機械的に安定な錠剤、特にアルギニン含有錠剤の製造における選択的に水分調整された打錠材料の使用
CN110575762B (zh) * 2018-06-07 2024-03-26 温州大学新材料与产业技术研究院 一种有机烷基钆水性分散体系的制备方法
EP4168001B1 (en) * 2020-06-19 2025-07-30 The Board of Trustees of the Leland Stanford Junior University An inhibitor of the activator protein 1 (ap-1) for preventing and treating adhesions
JP7495340B2 (ja) * 2020-12-16 2024-06-04 株式会社ファンケル カルノシン酸含有固体組成物及びカルノシン酸の溶出促進方法
CN118252824B (zh) * 2024-01-25 2024-09-17 中国医学科学院阜外医院 化合物用于治疗射血分数保留的心衰的用途
CN118255728B (zh) * 2024-01-25 2024-07-30 中国医学科学院阜外医院 化合物的盐型晶型用于治疗射血分数保留的心衰的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3670080A (en) * 1969-03-06 1972-06-13 Shionogi & Co Process for stabilization of a composition of 2{60 ,3{60 -epithio-androstanes and composition obtained thereby
JPS55129221A (en) 1979-03-29 1980-10-06 Kaken Pharmaceut Co Ltd Preparation of oral preparation containing hardly soluble medicine
JPS56110612A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Readily disintegrable and absorbable compression molded article of slightly soluble drug
JPS5942313A (ja) 1982-09-01 1984-03-08 Teijin Ltd ポリビニルポリピロリドンを用いた製剤
JPS60190723A (ja) * 1984-03-09 1985-09-28 Yamanouchi Pharmaceut Co Ltd 難溶性薬物の溶解速度向上方法
RO123430B1 (ro) * 2001-11-16 2012-04-30 Toyama Chemical Co., Ltd. Derivaţi noi de benzofenonă sau sărurile acestora

Also Published As

Publication number Publication date
SI2022497T1 (sl) 2014-08-29
ZA200810018B (en) 2010-02-24
CA2653023A1 (en) 2007-12-06
US20090163562A1 (en) 2009-06-25
PT2022497E (pt) 2014-07-17
EP2022497B1 (en) 2014-04-30
JPWO2007138997A1 (ja) 2009-10-08
US8093289B2 (en) 2012-01-10
RU2436576C2 (ru) 2011-12-20
CA2653023C (en) 2015-07-07
CN101454003B (zh) 2011-06-01
CY1115312T1 (el) 2017-01-04
PL2022497T3 (pl) 2014-09-30
IL195417A0 (en) 2009-08-03
NO20084634L (no) 2008-12-19
RU2008151757A (ru) 2010-07-10
AU2007268772B2 (en) 2012-03-15
JP5161077B2 (ja) 2013-03-13
EP2022497A1 (en) 2009-02-11
MX2008015015A (es) 2008-12-05
NZ573035A (en) 2010-08-27
IL195417A (en) 2014-03-31
KR20090021167A (ko) 2009-02-27
CN101454003A (zh) 2009-06-10
KR101394121B1 (ko) 2014-05-14
AU2007268772A1 (en) 2007-12-06
BRPI0709710A2 (pt) 2011-07-26
WO2007138997A1 (ja) 2007-12-06
ES2463455T3 (es) 2014-05-28
EP2022497A4 (en) 2013-02-13

Similar Documents

Publication Publication Date Title
DK2022497T3 (da) Oral sammensætning, omfattende 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-](3-hydroxy-1,2-benzisoxazol-6- yl)methoxyphenylpropionsyre eller salt deraf
CY2017038I2 (el) Νεες φαρμακευτικες συνθεσεις που περιεχουν 4-(4-(3-(4-χλωρο-3-τριφθορομεθυλ-φαινυλ)-ουρειδο)-3-φθορο-φαινοξυ)-πυριδιν-2-καρβοξυλικο οξυ για thν θεραπευτικη αγωγη υπερπολλαπλασιαστικων διαταραχων
DK2054428T3 (da) Udvikling af bestanddele til denque-virus-vaccine
RU2465270C3 (ru) Полиморфная форма 4-[3-(4-циклопропанкарбонилпиперазин-1-карбонил)-4-фторбензил]-2н-фталазин-1-она
DK2069338T3 (da) Insekticidale isoxazoliner
LU93312I2 (fr) Migalastat ou un sel de celui-ci, y compris le sel de chlorhydrate
DK2069374T4 (da) Krystallinske solvater af (1s)-1,5-anhydro-1-c-(3-((phenyl) methyl)phenyl)-d-glucitolderivater med alkoholer som sglt2-inhibitorer til behandling af diabetes
DK3170818T3 (da) Faste former af 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioxol-5-yl) cyclopropancarboxamido)-3-methylpyridin-2-yl)benzoesyre
DK2206710T3 (da) Indolderivater som s1p1-receptor agonister
CY2016017I1 (el) Συνθεση για θεραπεια πνευμονικης υπερτασης
BRPI0715617A2 (pt) Derivados do ácido fenoxifenilacético 4-substituído
DE602007000180D1 (de) Verbesserte chirurgische Kassette
DE602007000091D1 (de) Radialventilator
DK3252069T3 (da) (11.beta.,17.beta.)-17-hydroxy-11-[4-(methylsulfonyl)phenyl]-17-(pentalfuoromethyl)estra-4,9-dien-3-oner til behandling af sygdomme
DK2010220T3 (da) Stabiliserede pentosanpolysulfat-(pps)-formuleringer
DE602007002929D1 (de) Lichtempfindliche Zusammensetzung
EP1794167A4 (en) SUBSTITUTED ISOXAZOLE AS FUNGICIDES
BRPI0812321A2 (pt) Sais de ácido etilenodiamina dissuccínico, composição contendo os ditos sais, uso e método de preparação destes.
DK2053921T3 (da) Ny antifungal sammensætning
EP2214625A4 (en) EMULSION COMPOSITION
SMT201200063B (it) Composti 4-[2-(-fluorofenossimetil)fenil]piperidinici
DK2300452T3 (da) 5 -[5- [2-(3,5 -(bis(trifluoromethyl)phenyl) -2 - methylpropanoylmethylamino ]-4 -(4-fluoro -2-methylphenyl)]-2-pyridinyl -2-alkyl -prolinamid som NK1 receptor antagonister
BRPI0807992A2 (pt) Sais de adição do ácido, hidratos e polimorfos de etilamida do ácido 5-(2-4-di-hidróxi-5-isopropil-fenil)-4-(4-morfolin-4-ilme til-fenil) isoxazol-3-carboxílico e formulações compreendendo essas formas.
EP2245931A4 (en) EMULSION COMPOSITION
BRPI0817999A2 (pt) Composição oral compreendendo um agente de resfriamento