DK2032551T3 - Antitumorale dihydropyran-2-on-forbindelser - Google Patents

Antitumorale dihydropyran-2-on-forbindelser

Info

Publication number: DK2032551T3
Authority: DK; Denmark
Prior art keywords: compounds; antitumoral; dihydropyran; antitumoral dihydropyran
Prior art date: 2006-06-16

Application number

DK07765445.7T

Other languages

English (en)

Inventor

Lopez Ma Jesus Martin

Molinero Laura Coello

Benitez Jose Fernando Reyes

Vicente Alberto Rodriguez

Garcia-Ibarrola Maria Garranzo

Perez Carmen Murcia

Solloso Andres Francesch

Sancho Francisco Sanchez

Marchante Maria Del Carmen Cuevas

Rodriguez Rogelio Fernandez

Original Assignee

Pharma Mar Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-16

Filing date

2007-06-15

Publication date

2012-01-02

2007-06-15 Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa

2012-01-02 Application granted granted Critical

2012-01-02 Publication of DK2032551T3 publication Critical patent/DK2032551T3/da

Links

230000000259 anti-tumor effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pyrane Compounds (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK07765445.7T 2006-06-16 2007-06-15 Antitumorale dihydropyran-2-on-forbindelser DK2032551T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP06380173		2006-06-16
PCT/EP2007/055959 WO2007144423A1 (en)	2006-06-16	2007-06-15	Antitumoral dihydropyran-2-one compounds

Publications (1)

Publication Number	Publication Date
DK2032551T3 true DK2032551T3 (da)	2012-01-02

Family

ID=38508885

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07765445.7T DK2032551T3 (da)	2006-06-16	2007-06-15	Antitumorale dihydropyran-2-on-forbindelser

Country Status (29)

Country	Link
US (2)	US8324406B2 (da)
EP (3)	EP2404912A3 (da)
JP (2)	JP5117491B2 (da)
KR (1)	KR101474031B1 (da)
CN (2)	CN101679340B (da)
AR (1)	AR061506A1 (da)
AT (1)	ATE522514T1 (da)
AU (1)	AU2007259257B8 (da)
BR (2)	BRPI0713031B8 (da)
CA (1)	CA2654334C (da)
CY (1)	CY1112103T1 (da)
DK (1)	DK2032551T3 (da)
ES (1)	ES2371942T3 (da)
HR (1)	HRP20110845T1 (da)
IL (1)	IL195676A (da)
MX (1)	MX2008015754A (da)
MY (1)	MY145788A (da)
NO (2)	NO341508B1 (da)
NZ (1)	NZ573706A (da)
PL (1)	PL2032551T3 (da)
PT (1)	PT2032551E (da)
RS (1)	RS52034B (da)
RU (2)	RU2444519C2 (da)
SG (1)	SG174830A1 (da)
SI (1)	SI2032551T1 (da)
TW (2)	TWI373469B (da)
UA (1)	UA97369C2 (da)
WO (1)	WO2007144423A1 (da)
ZA (1)	ZA200810315B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0821116B8 (pt)	2007-12-20	2021-05-25	Pharma Mar Sa	composto, composição farmacêutica que o contem, uso deste e processo para a preparação do mesmo
ES2411930T3 (es)	2008-02-20	2013-07-09	Actelion Pharmaceuticals Ltd.	Compuestos antibióticos azatricíclicos
JP5404652B2 (ja)	2008-02-22	2014-02-05	アクテリオンファーマシューティカルズリミテッド	オキサゾリジノン誘導体
KR101294962B1 (ko)	2008-10-07	2013-08-12	액테리온 파마슈티칼 리미티드	트리사이클 옥사졸리디논 항생제 화합물
MX2011003188A (es)	2008-10-10	2011-04-27	Actelion Pharmaceuticals Ltd	Antibioticos de oxazolidinilo.
WO2010149688A2 (en)	2009-06-24	2010-12-29	Pharma Mar, S.A.	Antitumoral compounds
GB201309807D0 (en) *	2013-05-31	2013-07-17	Pharma Mar Sau	Antibody drug conjugates
CN108467378A (zh) *	2017-02-23	2018-08-31	复旦大学	一种二氢吡喃酮类化合物及其制备方法和用途
US11332480B2 (en)	2017-04-27	2022-05-17	Pharma Mar, S.A.	Antitumoral compounds
CN110790737B (zh) *	2019-11-07	2022-07-22	河南中烟工业有限责任公司	一种2,3-二氢-3,5-二羟基-6-乙基-4h-吡喃-4-酮的制备方法
EP4419513B1 (en)	2021-10-22	2025-08-27	Pharma Mar S.A.	Antitumoral compounds
CN117510448A (zh) *	2023-11-13	2024-02-06	贵州中医药大学	一种二氢吡喃酮衍生物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA938019B (en) *	1992-11-13	1995-04-28	Upjohn Co	Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses
ATE263761T1 (de) *	1993-11-19	2004-04-15	Parke Davis & Co	5,6-dihydropyronderivate als proteaseinhibitoren und antiviralmittel
US7446196B2 (en) *	2004-06-03	2008-11-04	Kosan Biosciences, Incorporated	Leptomycin compounds

2007
- 2007-06-15 AT AT07765445T patent/ATE522514T1/de active
- 2007-06-15 MX MX2008015754A patent/MX2008015754A/es active IP Right Grant
- 2007-06-15 BR BRPI0713031A patent/BRPI0713031B8/pt not_active IP Right Cessation
- 2007-06-15 ES ES07765445T patent/ES2371942T3/es active Active
- 2007-06-15 KR KR1020097000830A patent/KR101474031B1/ko not_active Expired - Fee Related
- 2007-06-15 PL PL07765445T patent/PL2032551T3/pl unknown
- 2007-06-15 UA UAA200900292A patent/UA97369C2/ru unknown
- 2007-06-15 EP EP11177474A patent/EP2404912A3/en not_active Withdrawn
- 2007-06-15 BR BRPI0722429-0A patent/BRPI0722429A2/pt not_active IP Right Cessation
- 2007-06-15 RU RU2009101150/04A patent/RU2444519C2/ru active
- 2007-06-15 RS RS20110495A patent/RS52034B/sr unknown
- 2007-06-15 EP EP11177479A patent/EP2404913A3/en not_active Withdrawn
- 2007-06-15 DK DK07765445.7T patent/DK2032551T3/da active
- 2007-06-15 MY MYPI20085040A patent/MY145788A/en unknown
- 2007-06-15 WO PCT/EP2007/055959 patent/WO2007144423A1/en not_active Ceased
- 2007-06-15 HR HR20110845T patent/HRP20110845T1/hr unknown
- 2007-06-15 AU AU2007259257A patent/AU2007259257B8/en not_active Ceased
- 2007-06-15 CN CN2007800222645A patent/CN101679340B/zh not_active Expired - Fee Related
- 2007-06-15 CA CA2654334A patent/CA2654334C/en active Active
- 2007-06-15 US US12/304,123 patent/US8324406B2/en not_active Expired - Fee Related
- 2007-06-15 NZ NZ573706A patent/NZ573706A/en not_active IP Right Cessation
- 2007-06-15 CN CN2011102036625A patent/CN102336730A/zh active Pending
- 2007-06-15 SI SI200730781T patent/SI2032551T1/sl unknown
- 2007-06-15 EP EP07765445A patent/EP2032551B9/en active Active
- 2007-06-15 JP JP2009514811A patent/JP5117491B2/ja not_active Expired - Fee Related
- 2007-06-15 SG SG2011067998A patent/SG174830A1/en unknown
- 2007-06-15 PT PT07765445T patent/PT2032551E/pt unknown
- 2007-06-19 AR ARP070102670A patent/AR061506A1/es active IP Right Grant
- 2007-06-20 TW TW096122071A patent/TWI373469B/zh not_active IP Right Cessation
- 2007-06-20 TW TW100146802A patent/TW201213316A/zh unknown
2008
- 2008-12-02 IL IL195676A patent/IL195676A/en active IP Right Grant
- 2008-12-04 ZA ZA2008/10315A patent/ZA200810315B/en unknown
2009
- 2009-01-06 NO NO20090054A patent/NO341508B1/no unknown
2011
- 2011-06-29 US US13/171,567 patent/US8501968B2/en not_active Expired - Fee Related
- 2011-08-05 RU RU2011133128/04A patent/RU2011133128A/ru not_active Application Discontinuation
- 2011-09-14 NO NO20111248A patent/NO20111248L/no not_active Application Discontinuation
- 2011-10-05 JP JP2011220925A patent/JP2012021023A/ja active Pending
- 2011-11-30 CY CY20111101175T patent/CY1112103T1/el unknown

Also Published As

Publication number	Publication date
CA2654334C (en)	2014-06-10
NO341508B1 (no)	2017-11-27
TW201213316A (en)	2012-04-01
JP2009539943A (ja)	2009-11-19
EP2404912A2 (en)	2012-01-11
ES2371942T3 (es)	2012-01-11
TWI373469B (en)	2012-10-01
HK1130052A1 (en)	2009-12-18
EP2404912A3 (en)	2012-07-25
JP5117491B2 (ja)	2013-01-16
SI2032551T1 (sl)	2012-01-31
NO20111248L (no)	2008-12-16
RU2444519C2 (ru)	2012-03-10
CY1112103T1 (el)	2015-11-04
PT2032551E (pt)	2011-12-06
IL195676A0 (en)	2009-09-01
RU2011133128A (ru)	2013-02-10
MY145788A (en)	2012-04-30
RS52034B (sr)	2012-04-30
AR061506A1 (es)	2008-09-03
KR20090024261A (ko)	2009-03-06
CN102336730A (zh)	2012-02-01
PL2032551T3 (pl)	2012-01-31
US8501968B2 (en)	2013-08-06
IL195676A (en)	2012-06-28
US8324406B2 (en)	2012-12-04
BRPI0713031B1 (pt)	2020-10-06
BRPI0713031B8 (pt)	2021-05-25
AU2007259257A1 (en)	2007-12-21
ZA200810315B (en)	2010-02-24
CN101679340A (zh)	2010-03-24
AU2007259257B8 (en)	2012-04-05
EP2404913A3 (en)	2012-06-06
NO20090054L (no)	2009-01-06
WO2007144423A1 (en)	2007-12-21
AU2007259257A8 (en)	2012-04-05
US20120190870A1 (en)	2012-07-26
JP2012021023A (ja)	2012-02-02
AU2007259257B2 (en)	2011-12-08
NZ573706A (en)	2011-09-30
HRP20110845T1 (hr)	2011-12-31
BRPI0713031A2 (pt)	2013-03-12
MX2008015754A (es)	2009-01-12
TW200811128A (en)	2008-03-01
EP2032551B1 (en)	2011-08-31
CN101679340B (zh)	2013-06-05
SG174830A1 (en)	2011-10-28
EP2032551A1 (en)	2009-03-11
KR101474031B1 (ko)	2014-12-17
RU2009101150A (ru)	2010-07-27
EP2404913A2 (en)	2012-01-11
EP2032551B9 (en)	2012-02-29
ATE522514T1 (de)	2011-09-15
BRPI0722429A2 (pt)	2013-11-26
US20090186938A1 (en)	2009-07-23
US20100048690A2 (en)	2010-02-25
UA97369C2 (ru)	2012-02-10
CA2654334A1 (en)	2007-12-21

Publication	Publication Date	Title
DE602006004717D1 (de)	2009-02-26	Kapselperforationsmodul
DE602007002544D1 (de)	2009-11-05	Nuancierungsmittel
DE602007008423D1 (de)	2010-09-23	Flüssigkeitshärtung
ATE524477T1 (de)	2011-09-15	Aziridinylepothilonverbindungen
DE602007009267D1 (de)	2010-10-28	Reifenaufblasverfahren
DE602007003893D1 (de)	2010-02-04	Kippambossanordnung
DE602007009650D1 (de)	2010-11-18	Spiroindolinonderivate
AT504580A3 (de)	2008-07-15	Scan-einrichtung
DE602007006947D1 (de)	2010-07-15	Pyridopyrimidinonderivate
DE602007000258D1 (de)	2009-01-02	Kassetteneinspannmechanismus
DE602007009337D1 (de)	2010-11-04	Tastfeedbackvorrichtung
DE602007001280D1 (de)	2009-07-30	Getränkeextraktor
DE602007008400D1 (de)	2010-09-23	Kaliummonopersulfatlösungen
DE602006020192D1 (de)	2011-03-31	Riemenscheibenanorndung
DE502007001629D1 (de)	2009-11-12	Rfahren
ATE546437T1 (de)	2012-03-15	Aminomethyl-4-imidazole
BRPI0720224A2 (pt)	2013-12-24	Arilpirazóis substituídos
DE502007000218D1 (de)	2008-12-18	nsetzungen
DE602007000501D1 (de)	2009-03-12	Breitbandrichtkoppler
DE602007001098D1 (de)	2009-06-25	Spindelmäheinheit
DE502007002453D1 (de)	2010-02-11	Kunstoffverdichtergehäuse
DE602007004080D1 (de)	2010-02-11	Tintenstrahlaufnehmer
DE602007007460D1 (de)	2010-08-12	Sehkrafttestsystem
NO20090054L (no)	2009-01-06	Antitumoral dihydropyran-2-on sammensetninger
DE502007000361D1 (de)	2009-02-26	Stanznieteinheit