DK20388D0 - Hidtil ukendt behandling - Google Patents

Hidtil ukendt behandling

Info

Publication number: DK20388D0
Authority: DK; Denmark
Prior art keywords: hydrogen; alkoxy; alkyl; halo; chem
Prior art date: 1987-01-19

Application number

DK020388A

Other languages

English (en)

Other versions

DK20388A (da

Inventor

C O Veecham Pharmaceuti Sanger

C O Beecham Pharmaceutica Marr

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-01-19

Filing date

1988-01-18

Publication date

1988-01-18

1988-01-18 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1988-01-18 Publication of DK20388D0 publication Critical patent/DK20388D0/da

1988-07-20 Publication of DK20388A publication Critical patent/DK20388A/da

Links

229910052739 hydrogen Inorganic materials 0.000 abstract 8
239000001257 hydrogen Substances 0.000 abstract 8
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 5
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
125000001475 halogen functional group Chemical group 0.000 abstract 3
241000124008 Mammalia Species 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000005236 alkanoylamino group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
-1 polymethylene Polymers 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000009935 visceral pain Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Saccharide Compounds (AREA)
Steroid Compounds (AREA)
Analysing Materials By The Use Of Radiation (AREA)
Processing Of Meat And Fish (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Mechanical Treatment Of Semiconductor (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Polarising Elements (AREA)
Hydrogenated Pyridines (AREA)

DK020388A 1987-01-19 1988-01-18 Anvendelse af 5-ht3-receptorantagonister til behandling af viscerale smerter DK20388A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB878701022A GB8701022D0 (en)	1987-01-19	1987-01-19	Treatment

Publications (2)

Publication Number	Publication Date
DK20388D0 true DK20388D0 (da)	1988-01-18
DK20388A DK20388A (da)	1988-07-20

Family

ID=10610829

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK020388A DK20388A (da)	1987-01-19	1988-01-18	Anvendelse af 5-ht3-receptorantagonister til behandling af viscerale smerter

Country Status (12)

Country	Link
US (3)	US4845092A (da)
EP (1)	EP0279512B1 (da)
JP (1)	JP2584266B2 (da)
KR (1)	KR880009020A (da)
AT (1)	ATE135911T1 (da)
AU (1)	AU608276B2 (da)
DE (1)	DE3855144T2 (da)
DK (1)	DK20388A (da)
ES (1)	ES2085259T3 (da)
GB (1)	GB8701022D0 (da)
GR (1)	GR3019447T3 (da)
ZA (1)	ZA88266B (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2828653B2 (ja) *	1989-04-13	1998-11-25	東ソー株式会社	接着性の改良されたポリフェニレンスルフィド樹脂組成物
IE913621A1 (en) *	1990-10-17	1992-04-22	Beecham Group Plc	Novel treatment
HU211081B (en) *	1990-12-18	1995-10-30	Sandoz Ag	Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
GB9214184D0 (en) *	1992-07-03	1992-08-12	Smithkline Beecham Plc	Pharmaceuticals
US5399562A (en) *	1994-02-04	1995-03-21	G. D. Searle & Co.	Indolones useful as serotonergic agents
GB9721139D0 (en)	1997-10-07	1997-12-03	Glaxo Group Ltd	Medicaments
ES2327600T3 (es) *	1999-02-18	2009-11-02	Novasearch Ag	Uso de antagonistas del receptor de la 5-ht3 para el tratamiento de enfermedades musculoesqueleticas.
US20040048874A1 (en) *	2001-05-22	2004-03-11	Bardsley Hazel Judith	New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine
GB0216027D0 (en) *	2002-07-10	2002-08-21	Arachnova Therapeutics Ltd	New therapeutic use
AR036041A1 (es)	2001-06-12	2004-08-04	Upjohn Co	Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
AR036040A1 (es)	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
JP2005527472A (ja) *	2001-09-12	2005-09-15	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	疾患治療のための置換された７−アザ［２．２．１］ビシクロヘプタン
HUP0402289A2 (hu)	2001-10-02	2005-02-28	Pharmacia & Upjohn Company	Gyógyhatású azabiciklusos csoporttal helyettesített kondenzált heteroaril-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
US6849620B2 (en)	2001-10-26	2005-02-01	Pfizer Inc	N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
US6951868B2 (en)	2001-11-09	2005-10-04	Pfizer Inc.	Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease
JP2005523288A (ja) *	2002-02-19	2005-08-04	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	疾病治療用の縮合した二環式−ｎ−架橋−複素環式芳香族カルボキサミド
AU2003217275A1 (en) *	2002-02-19	2003-09-09	Pharmacia And Upjohn Company	Azabicyclic compounds for the treatment of disease
MXPA05003317A (es) *	2002-09-25	2005-07-05	Memory Pharm Corp	Indazoles, benzotiazoles y benzoisotiazoles asi como preparacion y usos de los mismos.
WO2004039815A2 (en) *	2002-11-01	2004-05-13	Pharmacia & Upjohn Company Llc	Compounds having both alpha7 nachr agonist and 5ht antagonist activity for treatment of cns diseases
NZ541009A (en) *	2003-01-13	2007-09-28	Dynogen Pharmaceuticals Inc	Method of treating nausea, vomiting, retching or any combination thereof
MXPA05007381A (es) *	2003-01-13	2006-02-10	Dynogen Pharmaceuticals Inc	Metodo para el tratamiento de transtornos funcionales del intestino.
US20050113455A1 (en) *	2003-10-22	2005-05-26	Bergeron Raymond J.Jr.	Method and composition for amelioration of pain
DE602004010299T2 (de)	2003-12-22	2008-09-18	Memory Pharmaceuticals Corp.	Indole, 1h-indazole, 1,2-benzisoxazole und 1,2-benzisothiazole und deren herstellung und anwendungen
TW200533348A (en) *	2004-02-18	2005-10-16	Theravance Inc	Indazole-carboxamide compounds as 5-ht4 receptor agonists
US7820690B2 (en)	2004-03-19	2010-10-26	Solvay Pharmaceuticals Gmbh	Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist
CA2560279A1 (en) *	2004-03-19	2005-09-29	Solvay Pharmaceuticals Gmbh	Use of a 5-ht3 receptor antagonist for the manufacture of a medicament for the treatment of non-digestive tract derived abdominal disorders associated with pain
NZ550534A (en)	2004-03-25	2009-07-31	Memory Pharm Corp	Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
TWI351282B (en)	2004-04-07	2011-11-01	Theravance Inc	Quinolinone-carboxamide compounds as 5-ht4 recepto
US8309575B2 (en)	2004-04-07	2012-11-13	Theravance, Inc.	Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US7728006B2 (en) *	2004-04-07	2010-06-01	Theravance, Inc.	Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
WO2006001894A1 (en) *	2004-04-22	2006-01-05	Memory Pharmaceutical Corporation	Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
JP2007538011A (ja) *	2004-05-07	2007-12-27	メモリー・ファーマシューティカルズ・コーポレイション	１ｈ−インダゾール、ベンゾチアゾール、１，２−ベンゾイソキサゾール、１，２−ベンゾイソチアゾール、およびクロモン、ならびにそれらの調製および使用
US7399862B2 (en) *	2004-11-05	2008-07-15	Theravance, Inc.	5-HT4 receptor agonist compounds
WO2006052889A2 (en) *	2004-11-05	2006-05-18	Theravance, Inc.	Quinolinone-carboxamide compounds
JP2008523145A (ja) *	2004-12-13	2008-07-03	イーライリリーアンドカンパニー	リポキシゲナーゼ阻害剤としてのスピロ誘導体
RU2418797C2 (ru)	2004-12-22	2011-05-20	Мемори Фармасьютиклз Корпорейшн	Лиганды никотинового рецептора альфа-7, их получение и применение
CA2588037A1 (en) *	2004-12-22	2006-06-29	Theravance, Inc.	Indazole-carboxamide compounds
US20060160905A1 (en) *	2005-01-18	2006-07-20	Bergeron Raymond J Jr	Compositions and methods for inhibiting pain
CN101163701A (zh) *	2005-03-02	2008-04-16	施万制药	作为5-ht4受体激动剂的喹啉酮化合物
US20060293309A1 (en) *	2005-03-28	2006-12-28	Dynogen Pharmaceuticals, Inc.	Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
US8106066B2 (en)	2005-09-23	2012-01-31	Memory Pharmaceuticals Corporation	Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1220141A (en) *	1981-06-13	1987-04-07	John R. Fozard	Treatment of migraine with tropyl benzoate derivatives
FI74707C (fi) *	1982-06-29	1988-03-10	Sandoz Ag	Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
JPS5936675A (ja) *	1982-07-13	1984-02-28	サンド・アクチエンゲゼルシヤフト	二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
FR2557110B1 (fr) *	1983-12-23	1989-11-24	Sandoz Sa	Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
EP0189002B1 (en) *	1984-12-20	1993-03-03	Sandoz Ag	Treatment of gastrointestinal disorders using 5-ht3 antagonists
DE201165T1 (de) *	1985-03-14	1989-04-20	Beecham Group P.L.C., Brentford	Arzneimittel zur behandlung von emesis, anxietas und "irritable bowel syndrome".
GB8510752D0 (en) *	1985-04-27	1985-06-05	Beecham Group Plc	Compounds
GB8525913D0 (en) *	1985-10-21	1985-11-27	Beecham Group Plc	Compounds
DE3687080T2 (de) *	1985-04-27	1993-03-25	Beecham Group Plc	Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung.
EP0220011A3 (en) *	1985-10-12	1990-01-03	Beecham Group Plc	Use of azabicloalkylbenzamides in the treatment of gastrointestinal motility disorders, migraine, emesis, cluster headaches, trigeminal neuralgia and arrhythmia
ES2053451T3 (es) *	1986-01-07	1994-08-01	Beecham Group Plc	Un procedimiento para la preparacion de un compuesto que tiene propiedades farmacologicas utiles.
EP0235878A3 (en) *	1986-01-16	1989-06-14	Beecham Group Plc	Novel compounds

1987
- 1987-01-19 GB GB878701022A patent/GB8701022D0/en active Pending
1988
- 1988-01-15 ZA ZA88266A patent/ZA88266B/xx unknown
- 1988-01-18 DE DE3855144T patent/DE3855144T2/de not_active Expired - Fee Related
- 1988-01-18 EP EP88300376A patent/EP0279512B1/en not_active Expired - Lifetime
- 1988-01-18 KR KR1019880000325A patent/KR880009020A/ko not_active Withdrawn
- 1988-01-18 DK DK020388A patent/DK20388A/da not_active Application Discontinuation
- 1988-01-18 AT AT88300376T patent/ATE135911T1/de not_active IP Right Cessation
- 1988-01-18 ES ES88300376T patent/ES2085259T3/es not_active Expired - Lifetime
- 1988-01-18 AU AU10355/88A patent/AU608276B2/en not_active Ceased
- 1988-01-18 JP JP63008215A patent/JP2584266B2/ja not_active Expired - Lifetime
- 1988-01-19 US US07/145,537 patent/US4845092A/en not_active Expired - Fee Related
1989
- 1989-05-05 US US07/348,051 patent/US4942160A/en not_active Expired - Fee Related
1990
- 1990-05-07 US US07/520,108 patent/US5063231A/en not_active Expired - Fee Related
1996
- 1996-03-28 GR GR960400649T patent/GR3019447T3/el unknown

Also Published As

Publication number	Publication date
AU1035588A (en)	1988-07-21
JP2584266B2 (ja)	1997-02-26
EP0279512A3 (en)	1992-09-16
DE3855144T2 (de)	1996-08-22
AU608276B2 (en)	1991-03-28
ATE135911T1 (de)	1996-04-15
ZA88266B (en)	1988-11-30
GB8701022D0 (en)	1987-02-18
EP0279512A2 (en)	1988-08-24
US4845092A (en)	1989-07-04
EP0279512B1 (en)	1996-03-27
DE3855144D1 (de)	1996-05-02
JPS63215627A (ja)	1988-09-08
GR3019447T3 (en)	1996-06-30
DK20388A (da)	1988-07-20
US4942160A (en)	1990-07-17
ES2085259T3 (es)	1996-06-01
KR880009020A (ko)	1988-09-13
US5063231A (en)	1991-11-05

Legal Events

Date	Code	Title	Description
1997-09-15	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK20388D0 (da)	1988-01-18	Hidtil ukendt behandling
GB2268933B (en)	1996-04-10	Natural amino acid derivatives as metalloproteinase inhibitors
DE3860960D1 (de)	1990-12-13	Arylcyclobutylalkylamin-derivat zur behandlung von morbus parkinson.
DK0641330T3 (da)	2001-12-03	Gaba- og L-glutaminsyreanaloger til antikrampeanfaldsbehandling
DK359289D0 (da)	1989-07-19	4-oxoquinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf samt deres anvendelse
IL95440A0 (en)	1991-06-30	Substituted urea compounds,their preparation and pharmaceutical compositions containing them
DE68914292D1 (de)	1994-05-11	Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
DE3881489D1 (de)	1993-07-08	Peptide mit collagenase hemmender wirkung.
ES8301225A1 (es)	1982-12-01	Un procedimiento para la preparacion de un derivado de 3- aril-5-isotiazol
IL82395A (en)	1992-02-16	Derivatives of 7-amino-6-halo-4-oxo-1,3-thiazeto(3,2-a)quinoline-3-carboxylic acid and their preparation
FI860107A7 (fi)	1987-07-11	Aminofenolderivat.
ZA89389B (en)	1989-10-25	Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
ZA881726B (en)	1989-11-29	Method of treating anxiety with tetrahydrobenz(c,d)indole-6-carbozamides
GB8803259D0 (en)	1988-03-09	Compounds
PT96788A (pt)	1991-10-31	Processo de preparacao de compostos de ureia substituida e de composicoes farmaceuticas
HU9600996D0 (en)	1996-06-28	Nitric esters from derivatives of 2-(2,6-dihalophenyl-amino)-phenylacetoxyacetic acid and their preparation procedures
SE8503054D0 (sv)	1985-06-19	Catecholcarboxamides
IT1205114B (it)	1989-03-15	2-selenometil-1,4-diidropiridine,procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
ATE81465T1 (de)	1992-10-15	Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten.
IT1271937B (it)	1997-06-10	Derivato peptidico della rimantadina di attivita' immunomodulante