DK2059513T3 - Fremgangsmåde til fremstillingen af 1,2,4-oxadiazolbenzoesyrer - Google Patents

Fremgangsmåde til fremstillingen af 1,2,4-oxadiazolbenzoesyrer

Info

Publication number: DK2059513T3
Authority: DK; Denmark
Prior art keywords: preparation; benzoic acids; oxadiazole benzoic; oxadiazole; acids
Prior art date: 2006-09-08

Application number

DK07837899.9T

Other languages

English (en)

Inventor

Neil G Almstead

Peter Seongwoo Hwang

Seemon Pines

Young-Choon Moon

James J Takasugi

Original Assignee

Ptc Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-08

Filing date

2007-09-06

Publication date

2013-05-06

2007-09-06 Application filed by Ptc Therapeutics Inc filed Critical Ptc Therapeutics Inc

2013-05-06 Application granted granted Critical

2013-05-06 Publication of DK2059513T3 publication Critical patent/DK2059513T3/da

Links

SNGNHEIIYFNIIL-UHFFFAOYSA-N benzoic acid;1,2,4-oxadiazole Chemical class C=1N=CON=1.OC(=O)C1=CC=CC=C1 SNGNHEIIYFNIIL-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK07837899.9T 2006-09-08 2007-09-06 Fremgangsmåde til fremstillingen af 1,2,4-oxadiazolbenzoesyrer DK2059513T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US84359506P	2006-09-08	2006-09-08
PCT/US2007/019561 WO2008030570A1 (en)	2006-09-08	2007-09-06	Processes for the preparation of 1,2,4-oxadiazole benzoic acids

Publications (1)

Publication Number	Publication Date
DK2059513T3 true DK2059513T3 (da)	2013-05-06

Family

ID=38935880

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07837899.9T DK2059513T3 (da)	2006-09-08	2007-09-06	Fremgangsmåde til fremstillingen af 1,2,4-oxadiazolbenzoesyrer

Country Status (24)

Country	Link
US (2)	US7678922B2 (da)
EP (1)	EP2059513B1 (da)
JP (2)	JP5955494B2 (da)
KR (1)	KR101466368B1 (da)
CN (1)	CN101535284B (da)
AR (3)	AR062715A1 (da)
AU (1)	AU2007292915B2 (da)
BR (1)	BRPI0716996B8 (da)
CA (2)	CA2842625C (da)
CL (1)	CL2007002606A1 (da)
DK (1)	DK2059513T3 (da)
ES (1)	ES2404348T3 (da)
IL (1)	IL197445A (da)
MX (1)	MX2009002439A (da)
MY (1)	MY148598A (da)
NZ (2)	NZ575511A (da)
PE (2)	PE20120669A1 (da)
PL (1)	PL2059513T3 (da)
PT (1)	PT2059513E (da)
RU (1)	RU2495030C2 (da)
TW (1)	TWI482761B (da)
UA (1)	UA99265C2 (da)
WO (1)	WO2008030570A1 (da)
ZA (1)	ZA200901782B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2887054T3 (es)	2003-04-11	2021-12-21	Ptc Therapeutics Inc	Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades
CA2603402C (en)	2005-04-08	2017-10-31	Ptc Therapeutics, Inc.	Compositions of an orally active 1,2,4-oxadiazole for nonsense mutation suppression therapy
IN2014CN04406A (da) *	2006-03-30	2015-09-04	Ptc Therapeutics Inc
PT2059513E (pt) *	2006-09-08	2013-04-30	Ptc Therapeutics Inc	Processo para a preparação de ácidos 1,2,4-oxadiazolebenzóicos
SG10201609581TA (en)	2006-09-25	2016-12-29	Ptc Therapeutics Inc	Crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid
WO2008130370A1 (en)	2006-09-25	2008-10-30	Ptc Therapeutics, Inc.	Hydroxylated 1,2,4-oxadiazole benzoic acid compounds, compositions thereof and the use for nonsense suppression
CL2007002923A1 (es)	2006-10-12	2008-06-06	Ptc Therapeutics Inc Soc Organ	Metodo para el tratamiento, prevencion o manejo de una enfermedad asociada con una mutacion sin sentido tal como cancer, diabetes o enfermedad pulmonar, que consiste en administrar a un paciente una cantidad efectiva de acido 3-[5-(2-fluoro-fenil)-[1
CN101714009A (zh) *	2009-05-14	2010-05-26	翁印嵩	集成通用电话功能的计算机
US9050347B2 (en)	2011-01-25	2015-06-09	Viviabiotech, S.L.	1,2,4-oxadiazole derivatives as drugs modulating the GLP-1 peptide receptor
CA2876215A1 (en)	2012-07-02	2014-01-09	Monsanto Technology Llc	Processes for the preparation of 3,5-disubstituted-1,2,4-oxadiazoles
TWI695717B (zh) *	2014-03-06	2020-06-11	美商 Ptc 治療公司	１,２,４-二唑苯甲酸之鹽及醫藥組合物
CN105461650B (zh) *	2014-09-12	2018-04-13	杭州普晒医药科技有限公司	一种噁二唑化合物的溶剂化物及其制备方法
CN106316885B (zh) *	2015-07-03	2019-02-12	普济生物科技（台州）有限公司	一种3-[5-(2-氟苯基)-1,2,4-噁二唑-3-基]苯甲酸的制备方法
HK1251965A1 (zh)	2015-10-30	2019-05-10	Ptc医疗公司	用於治疗癫痫的方法
TW201808922A (zh)	2016-06-20	2018-03-16	台灣神隆股份有限公司	製備阿塔魯仁及其中間體的方法
WO2020128816A2 (en)	2018-12-20	2020-06-25	Pfizer Inc.	Pharmaceutical compositions and methods comprising a combination of a benzoxazole transthyretin stabilizer and an additional therapeutic agent
JP2022526643A (ja)	2019-04-10	2022-05-25	ピーティーシーセラピューティクス，インコーポレーテッド	小児患者においてナンセンス変異が介在するデュシェンヌ型筋ジストロフィーを治療するための方法
WO2022112919A1 (en)	2020-11-25	2022-06-02	Pfizer Inc.	(aza)benzothiazolyl substituted pyrazole compounds
CN113045510B (zh) *	2021-03-31	2022-05-27	北京大学生命科学华东产业研究院	一种阿塔鲁伦的制备方法
CN114920667B (zh) *	2022-06-30	2024-06-21	湖南大学	一种阿塔鲁伦酯的电化学制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2801509A1 (de) *	1978-01-12	1979-07-19	Schering Ag	1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel
DE3905242A1 (de) *	1989-02-21	1990-08-23	Basf Ag	Verfahren zur herstellung von phenyloxdiazolylanilinen
NZ234760A (en) *	1989-08-18	1991-09-25	Sterling Drug Inc	Antiviral oxazole compounds and compositions
DE4425794A1 (de) *	1994-07-21	1996-01-25	Basf Ag	Nitrofarbstoffe
US6660753B2 (en) *	1999-08-19	2003-12-09	Nps Pharmaceuticals, Inc.	Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
CA2449544A1 (en) *	2001-06-08	2002-12-19	Cytovia, Inc.	Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs
MY151199A (en) *	2001-11-02	2014-04-30	Rigel Pharmaceuticals Inc	Substituted diphenyl heterocycles useful for treating hcv infection
TW200424183A (en) *	2002-08-09	2004-11-16	Nps Pharma Inc	New compounds
GB0303503D0 (en)	2003-02-14	2003-03-19	Novartis Ag	Organic compounds
ES2887054T3 (es) *	2003-04-11	2021-12-21	Ptc Therapeutics Inc	Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades
WO2004110351A2 (en) *	2003-05-14	2004-12-23	Anadys Pharmaceuticals, Inc.	Heterocyclic compounds for treating hepatitis c virus
CA2603402C (en)	2005-04-08	2017-10-31	Ptc Therapeutics, Inc.	Compositions of an orally active 1,2,4-oxadiazole for nonsense mutation suppression therapy
PT2059513E (pt) *	2006-09-08	2013-04-30	Ptc Therapeutics Inc	Processo para a preparação de ácidos 1,2,4-oxadiazolebenzóicos

2007
- 2007-09-06 PT PT78378999T patent/PT2059513E/pt unknown
- 2007-09-06 UA UAA200903350A patent/UA99265C2/ru unknown
- 2007-09-06 RU RU2009113019/04A patent/RU2495030C2/ru active
- 2007-09-06 EP EP07837899A patent/EP2059513B1/en active Active
- 2007-09-06 DK DK07837899.9T patent/DK2059513T3/da active
- 2007-09-06 MX MX2009002439A patent/MX2009002439A/es active IP Right Grant
- 2007-09-06 NZ NZ575511A patent/NZ575511A/en unknown
- 2007-09-06 ES ES07837899T patent/ES2404348T3/es active Active
- 2007-09-06 CA CA2842625A patent/CA2842625C/en active Active
- 2007-09-06 AU AU2007292915A patent/AU2007292915B2/en active Active
- 2007-09-06 ZA ZA200901782A patent/ZA200901782B/xx unknown
- 2007-09-06 WO PCT/US2007/019561 patent/WO2008030570A1/en not_active Ceased
- 2007-09-06 US US11/899,813 patent/US7678922B2/en active Active - Reinstated
- 2007-09-06 NZ NZ598012A patent/NZ598012A/xx unknown
- 2007-09-06 JP JP2009527430A patent/JP5955494B2/ja active Active
- 2007-09-06 CN CN200780041169.XA patent/CN101535284B/zh active Active
- 2007-09-06 CA CA2662749A patent/CA2662749C/en active Active
- 2007-09-06 BR BRPI0716996A patent/BRPI0716996B8/pt active IP Right Grant
- 2007-09-06 KR KR1020097007202A patent/KR101466368B1/ko not_active Expired - Fee Related
- 2007-09-06 MY MYPI20090941A patent/MY148598A/en unknown
- 2007-09-06 PL PL07837899T patent/PL2059513T3/pl unknown
- 2007-09-07 CL CL200702606A patent/CL2007002606A1/es unknown
- 2007-09-07 PE PE2011001405A patent/PE20120669A1/es active IP Right Grant
- 2007-09-07 AR ARP070103975A patent/AR062715A1/es not_active Application Discontinuation
- 2007-09-07 PE PE2007001203A patent/PE20080771A1/es active IP Right Grant
- 2007-09-07 TW TW096133607A patent/TWI482761B/zh active
2009
- 2009-03-05 IL IL197445A patent/IL197445A/en active IP Right Grant
- 2009-11-13 US US12/617,757 patent/US8367841B2/en active Active
2014
- 2014-05-20 JP JP2014103966A patent/JP2014193896A/ja active Pending
2017
- 2017-01-27 AR ARP170100223A patent/AR107474A2/es not_active Application Discontinuation
2020
- 2020-05-12 AR ARP200101362A patent/AR118922A2/es active IP Right Grant

Also Published As

Publication number	Publication date
ES2404348T3 (es)	2013-05-27
MY148598A (en)	2013-05-15
CA2662749A1 (en)	2008-03-13
US20100063297A1 (en)	2010-03-11
NZ598012A (en)	2013-08-30
PE20120669A1 (es)	2012-06-01
IL197445A (en)	2014-01-30
NZ575511A (en)	2012-02-24
EP2059513B1 (en)	2013-01-23
AU2007292915B2 (en)	2012-07-26
CA2842625C (en)	2016-07-12
IL197445A0 (en)	2009-12-24
US7678922B2 (en)	2010-03-16
AU2007292915A1 (en)	2008-03-13
PL2059513T3 (pl)	2013-06-28
AR062715A1 (es)	2008-11-26
CA2662749C (en)	2015-01-20
KR101466368B1 (ko)	2014-11-27
RU2009113019A (ru)	2010-10-20
TW200823180A (en)	2008-06-01
PT2059513E (pt)	2013-04-30
KR20090054464A (ko)	2009-05-29
CN101535284B (zh)	2014-12-10
AR118922A2 (es)	2021-11-10
PE20080771A1 (es)	2008-06-13
CA2842625A1 (en)	2008-03-13
JP2010502715A (ja)	2010-01-28
BRPI0716996B8 (pt)	2021-05-25
CL2007002606A1 (es)	2008-04-18
BRPI0716996A2 (pt)	2013-10-08
EP2059513A1 (en)	2009-05-20
JP5955494B2 (ja)	2016-07-20
US8367841B2 (en)	2013-02-05
HK1134094A1 (en)	2010-04-16
US20080139818A1 (en)	2008-06-12
TWI482761B (zh)	2015-05-01
JP2014193896A (ja)	2014-10-09
CN101535284A (zh)	2009-09-16
WO2008030570A1 (en)	2008-03-13
UA99265C2 (ru)	2012-08-10
ZA200901782B (en)	2010-06-30
MX2009002439A (es)	2009-03-27
AR107474A2 (es)	2018-05-02
BRPI0716996B1 (pt)	2021-02-09
RU2495030C2 (ru)	2013-10-10

Publication	Publication Date	Title
IL197445A0 (en)	2009-12-24	Processes for the preparation of 1,2,4-oxadiazole benzoic acids
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