DK2061886T3 - Små kationiske immunomodulerende peptider - Google Patents

Små kationiske immunomodulerende peptider

Info

Publication number
DK2061886T3
DK2061886T3 DK07800481.9T DK07800481T DK2061886T3 DK 2061886 T3 DK2061886 T3 DK 2061886T3 DK 07800481 T DK07800481 T DK 07800481T DK 2061886 T3 DK2061886 T3 DK 2061886T3
Authority
DK
Denmark
Prior art keywords
modulating peptides
small cationic
immuno modulating
immuno
cationic
Prior art date
Application number
DK07800481.9T
Other languages
English (en)
Inventor
Robert E W Hancock
Kai Hilpert
Artem Cherkasov
Christopher Fjell
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Application granted granted Critical
Publication of DK2061886T3 publication Critical patent/DK2061886T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Toxicology (AREA)
  • Environmental Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK07800481.9T 2006-08-21 2007-08-21 Små kationiske immunomodulerende peptider DK2061886T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83925306P 2006-08-21 2006-08-21
PCT/CA2007/001453 WO2008022444A1 (en) 2006-08-21 2007-08-21 Small cationic antimicrobial peptides

Publications (1)

Publication Number Publication Date
DK2061886T3 true DK2061886T3 (da) 2014-08-11

Family

ID=39106434

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07800481.9T DK2061886T3 (da) 2006-08-21 2007-08-21 Små kationiske immunomodulerende peptider

Country Status (9)

Country Link
US (3) US8343475B2 (da)
EP (1) EP2061886B1 (da)
AU (1) AU2007288080B2 (da)
CA (1) CA2660668C (da)
DK (1) DK2061886T3 (da)
ES (1) ES2497441T3 (da)
NZ (1) NZ574758A (da)
PL (1) PL2061886T3 (da)
WO (1) WO2008022444A1 (da)

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CA2660668C (en) 2006-08-21 2016-06-28 The University Of British Columbia Small cationic antimicrobial peptides
ES2548767T3 (es) 2007-01-16 2015-10-20 The Regents Of The University Of California Nuevos péptidos antimicrobianos
ATE533780T1 (de) 2008-06-02 2011-12-15 Spiderbiotech Srl Antibakterielle peptide
AU2009304552B2 (en) * 2008-10-16 2015-02-19 Dalhousie University Combination adjuvant formulation
GB0821616D0 (en) * 2008-11-26 2008-12-31 Lytix Biopharma As Compounds
IT1395137B1 (it) * 2009-08-05 2012-09-05 Spider Biotech S R L Nuovi peptidi antipatogeni
AU2010306940A1 (en) 2009-10-12 2012-06-07 Smith, Larry Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
CN101696417B (zh) * 2009-11-02 2012-12-26 查向东 共表达阴离子配体生产重组阳离子抗菌肽的方法
GB201016733D0 (en) * 2010-10-05 2010-11-17 Novabiotics Ltd Compounds and their use
WO2011156903A2 (en) * 2010-06-15 2011-12-22 University Of Manitoba Innate defence regulatory peptide compositions for treatment of arthritis
EP2613797B1 (en) 2010-09-09 2015-11-04 University Of Southern California Compositions and methods for the removal of biofilms
US9303063B2 (en) 2011-03-18 2016-04-05 Duke University Peptide compounds for suppressing inflammation
AU2012231268B2 (en) * 2011-03-18 2017-02-02 Duke University Peptides for suppressing inflammation
US9187541B2 (en) 2011-04-27 2015-11-17 The Regents Of The University Of California Anti-microbial peptides and methods of use thereof
WO2013034982A2 (en) * 2011-09-09 2013-03-14 The University Of British Columbia Immunomodulatory peptides for treatment of progressive neurodegenerative diseases
EP2766031B1 (en) * 2011-10-10 2016-07-27 Berecz, Roland Antimicrobial peptides for treatment of infectious diseases
WO2013077982A1 (en) 2011-11-22 2013-05-30 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf High throughput selection of specific cell binding and lytic polypeptides
MY151307A (en) * 2012-06-18 2014-05-05 Univ Malaya Peptides having antimicrobial activity
MY151112A (en) * 2012-06-18 2014-04-10 Univ Malaya Peptides having antimicrobial activity
US9200082B2 (en) * 2013-03-14 2015-12-01 The University Of Chicago Methods and compositions involving fibrillizing polypeptides for nanofibers
US11274144B2 (en) 2013-06-13 2022-03-15 Research Institute At Nationwide Children's Hospital Compositions and methods for the removal of biofilms
US20160289287A1 (en) * 2013-08-27 2016-10-06 The University Of British Columbia Small cationic anti-biofilm and idr peptides
US11248040B2 (en) 2013-09-26 2022-02-15 Trellis Bioscience, Llc Binding moieties for biofilm remediation
WO2015065916A1 (en) * 2013-10-31 2015-05-07 East Carolina University Anti microbial peptides incorporating cyclic alpha tetra-substituted unnatural amino acids
DE102014101663A1 (de) * 2014-02-11 2015-08-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Synthetische artifizielle Peptide mit antimikrobieller Wirkung
WO2015138494A1 (en) 2014-03-10 2015-09-17 Georges Belfort Anti-microbial peptides and method for designing novel anti-microbial peptides
US10507227B2 (en) * 2014-04-15 2019-12-17 The Hospital For Sick Children Cationic antimicrobial peptides
US10351599B2 (en) 2014-09-19 2019-07-16 Tensive Controls, Inc. Anti-microbial peptides
WO2016132377A1 (en) * 2015-02-18 2016-08-25 Indian Council Of Medical Research A peptide to neutralize lipopolysaccharide molecule
US20180207067A1 (en) 2015-07-14 2018-07-26 Research Institute at Nationwide Children's Hospit al Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity
WO2017023863A1 (en) 2015-07-31 2017-02-09 Research Institute At Nationwide Children's Hospital Peptides and antibodies for the removal of biofilms
EP3365027B1 (en) 2015-10-14 2022-03-30 Research Institute at Nationwide Children's Hospital Hu specific antibodies and their use in inhibiting biofilm
CN113521007B (zh) 2016-07-01 2022-11-18 四川大学 抗菌肽衍生物在制备免疫佐剂中的用途
JP7661008B2 (ja) 2017-01-04 2025-04-14 リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル バイオフィルム関連障害の処置のための抗体断片
US11564982B2 (en) 2017-01-04 2023-01-31 Research Institute At Nationwide Children's Hospital DNABII vaccines and antibodies with enhanced activity
RU2678985C2 (ru) * 2017-02-06 2019-02-05 Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" Биоцидный пептид и препарат на его основе
WO2018160997A1 (en) * 2017-03-03 2018-09-07 Peptilogics, Inc. Engineered antimicrobial amphiphilic peptides and methods of use
WO2018170178A1 (en) 2017-03-15 2018-09-20 Research Institute At Nationwide Children's Hospital Composition and methods for disruption of bacterial biofilms without accompanying inflammation
WO2018226614A1 (en) 2017-06-05 2018-12-13 The Penn State Research Foundation Inhalable antimicrobial particles and methods of making the same
US11571454B2 (en) 2017-06-05 2023-02-07 The Penn State Research Foundation Anticancer peptides that synergistically enhance chemotherapeutic potency
AU2019354829B2 (en) 2018-10-05 2025-04-17 Research Institute At Nationwide Children's Hospital Hmgb1 protein derivatives for the removal of biofilms
US12173088B2 (en) 2018-10-10 2024-12-24 Board Of Regents Of The University Of Nebraska Anti-microbial peptides
JP7755994B2 (ja) * 2018-10-19 2025-10-17 リップタイド バイオサイエンス インコーポレイテッド 抗菌性ペプチド及びその使用方法
CN109553657B (zh) * 2018-11-30 2021-10-19 东北农业大学 一种非完美两亲性肽w4及其制备方法和应用
KR102170236B1 (ko) * 2019-03-19 2020-10-29 (주)노바셀테크놀로지 신규 다중 기능성 펩타이드 및 그의 용도
KR20210151945A (ko) 2019-04-12 2021-12-14 립타이드 바이오사이언스, 인코포레이티드 대식세포 활성을 조정하기 위한 방법
US20220389057A1 (en) * 2019-06-07 2022-12-08 Szegedi Tudományegyetem Endocytosis routing sequence peptide for cell delivery systems
CN111253470B (zh) * 2019-11-22 2023-01-10 宁波大学 免疫调节因子idr-1018衍生肽及其应用
CN110903347A (zh) * 2019-12-05 2020-03-24 中国人民解放军陆军军医大学第一附属医院 抗菌肽l7及其应用
KR102220323B1 (ko) * 2020-05-15 2021-02-26 (주)노바셀테크놀로지 신규 다중 기능성 펩타이드 및 그의 용도
US11174289B1 (en) 2020-05-21 2021-11-16 International Business Machines Corporation Artificial intelligence designed antimicrobial peptides
US12079730B2 (en) 2020-05-28 2024-09-03 International Business Machines Corporation Transfer learning for molecular structure generation
BR102021021376A2 (pt) * 2021-10-25 2023-05-09 União Brasileira De Educação Católica - Ubec Composição, processo de produção da composição e uso da composição de nanofibras que compreende pva, quitosana, antibiótico e peptídeo de defesa do hospedeiro
CN116240252B (zh) * 2021-12-08 2026-03-24 中国医学科学院医药生物技术研究所 十三肽衍生物及其制备方法和应用
WO2024175780A1 (en) * 2023-02-23 2024-08-29 Micropep Technologies S.A. Micropeptides to improve plant immunity and application thereof
WO2025183585A1 (ru) * 2024-03-01 2025-09-04 Общество с ограниченной ответственностью "Альбоген" Пептид с антибактериальной активностью

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CA2660668C (en) 2006-08-21 2016-06-28 The University Of British Columbia Small cationic antimicrobial peptides

Also Published As

Publication number Publication date
CA2660668C (en) 2016-06-28
EP2061886B1 (en) 2014-05-07
AU2007288080A1 (en) 2008-02-28
EP2061886A1 (en) 2009-05-27
US20130266597A1 (en) 2013-10-10
WO2008022444A1 (en) 2008-02-28
CA2660668A1 (en) 2008-02-28
AU2007288080B2 (en) 2013-07-04
EP2061886A4 (en) 2010-12-08
US8343475B2 (en) 2013-01-01
NZ574758A (en) 2012-03-30
US20110236429A1 (en) 2011-09-29
ES2497441T3 (es) 2014-09-22
US9707282B2 (en) 2017-07-18
US20150315240A1 (en) 2015-11-05
PL2061886T3 (pl) 2014-10-31
US9017656B2 (en) 2015-04-28

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