DK2079767T3 - Fremstilling af bionedbrydelige polyestere med lave burst-egenskaber ved ekstraktion med et superkritisk fluid - Google Patents

Fremstilling af bionedbrydelige polyestere med lave burst-egenskaber ved ekstraktion med et superkritisk fluid

Info

Publication number
DK2079767T3
DK2079767T3 DK07839468T DK07839468T DK2079767T3 DK 2079767 T3 DK2079767 T3 DK 2079767T3 DK 07839468 T DK07839468 T DK 07839468T DK 07839468 T DK07839468 T DK 07839468T DK 2079767 T3 DK2079767 T3 DK 2079767T3
Authority
DK
Denmark
Prior art keywords
extraction
preparation
critical fluid
super critical
biodegradable polyesters
Prior art date
Application number
DK07839468T
Other languages
English (en)
Inventor
Lester Moore
Richard L Norton
Original Assignee
Tolmar Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tolmar Therapeutics Inc filed Critical Tolmar Therapeutics Inc
Application granted granted Critical
Publication of DK2079767T3 publication Critical patent/DK2079767T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/08—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F289/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88—Post-polymerisation treatment
    • C08G63/90—Purification; Drying
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J11/00—Recovery or working-up of waste materials
    • C08J11/04—Recovery or working-up of waste materials of polymers
    • C08J11/06—Recovery or working-up of waste materials of polymers without chemical reactions
    • C08J11/08—Recovery or working-up of waste materials of polymers without chemical reactions using selective solvents for polymer components
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
    • C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W30/00—Technologies for solid waste management
    • Y02W30/50—Reuse, recycling or recovery technologies
    • Y02W30/62—Plastics recycling; Rubber recycling

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Sustainable Development (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK07839468T 2006-10-11 2007-10-11 Fremstilling af bionedbrydelige polyestere med lave burst-egenskaber ved ekstraktion med et superkritisk fluid DK2079767T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85074406P 2006-10-11 2006-10-11
PCT/US2007/021749 WO2008045516A1 (en) 2006-10-11 2007-10-11 Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction

Publications (1)

Publication Number Publication Date
DK2079767T3 true DK2079767T3 (da) 2014-10-27

Family

ID=39283171

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07839468T DK2079767T3 (da) 2006-10-11 2007-10-11 Fremstilling af bionedbrydelige polyestere med lave burst-egenskaber ved ekstraktion med et superkritisk fluid

Country Status (9)

Country Link
EP (1) EP2079767B1 (da)
JP (1) JP5647788B2 (da)
CA (1) CA2666341C (da)
DK (1) DK2079767T3 (da)
ES (1) ES2516695T3 (da)
PL (1) PL2079767T3 (da)
PT (1) PT2079767E (da)
SI (1) SI2079767T1 (da)
WO (1) WO2008045516A1 (da)

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* Cited by examiner, † Cited by third party
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US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
WO2007084460A2 (en) 2006-01-18 2007-07-26 Qps, Llc Pharmaceutical compositions with enhanced stability
US8076448B2 (en) 2006-10-11 2011-12-13 Tolmar Therapeutics, Inc. Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction
DK3660073T3 (da) 2007-02-15 2023-09-18 Tolmar International Ltd Poly(lactid-co-glycolid) med lav sprængning
ES2562878T3 (es) * 2007-05-25 2016-03-08 Indivior Uk Limited Formulaciones de liberación sostenida de compuestos de risperidona
WO2009148580A2 (en) * 2008-06-03 2009-12-10 Qlt Usa, Inc. Controlled release copolymer formulation with improved release kinetics
GB0812740D0 (en) * 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Composition
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
US9889238B2 (en) 2009-07-21 2018-02-13 Abbott Cardiovascular Systems Inc. Biodegradable stent with adjustable degradation rate
US8889823B2 (en) 2009-07-21 2014-11-18 Abbott Cardiovascular Systems Inc. Method to make poly(L-lactide) stent with tunable degradation rate
PL2394663T3 (pl) * 2010-05-31 2022-02-21 Laboratorios Farmaceuticos Rovi, S.A. Kompozycje do wstrzykiwania implantów biodegradowalnych in-situ
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
GB2513060B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
ES2387906B1 (es) * 2011-01-27 2013-10-30 Universidad Autónoma de Madrid Fluido supercrítico y su empleo en procedimientos de fraccionamiento supercrítico para la purificación de lisofosfolípidos.
WO2012138265A1 (en) * 2011-04-04 2012-10-11 Sca Packaging Sweden Ab Highly purified material comprising expanded polylactid acid resin
WO2012138282A1 (en) * 2011-04-04 2012-10-11 Siox Machines Ab Method of impregnating and purifying polylactic acid resin
TWI636799B (zh) * 2012-05-14 2018-10-01 日商帝人股份有限公司 滅菌組成物
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
CA3015557C (en) 2014-11-07 2019-07-16 Indivior Uk Limited The use of sustained-release buprenorphine formulations for the treatment of pain or opioid use disorders
DE102015215387A1 (de) 2015-08-12 2017-02-16 Evonik Degussa Gmbh Verfahren zur Herstellung von Polyalkenameren für Verpackungsanwendungen
GB2560726B (en) * 2017-03-22 2022-12-21 Worn Again Tech Limited Dissolution process
US10646484B2 (en) 2017-06-16 2020-05-12 Indivior Uk Limited Methods to treat opioid use disorder
KR102884866B1 (ko) * 2018-11-27 2025-11-13 에보니크 오퍼레이션즈 게엠베하 벌크 중합에 의한 과립 또는 분말로서의 재흡수성 폴리에스테르의 제조 방법
CN112798693B (zh) * 2019-11-13 2023-11-21 浙江圣兆药物科技股份有限公司 一种在微球制备过程中准确监控plg分子量变化的方法
WO2021253009A2 (en) 2020-06-12 2021-12-16 Cornell University Polymerizations in supercritical carbon dioxide, products of same, and uses thereof
TWI766511B (zh) * 2020-12-28 2022-06-01 財團法人工業技術研究院 聚酯纖維的脫色方法

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Publication number Priority date Publication date Assignee Title
US5338822A (en) * 1992-10-02 1994-08-16 Cargill, Incorporated Melt-stable lactide polymer composition and process for manufacture thereof
US5478921A (en) * 1994-08-25 1995-12-26 United States Surgical Corporation Method of purifying bioabsorable polymer
JP3669803B2 (ja) * 1997-03-10 2005-07-13 三井化学株式会社 ポリエステル系樹脂の精製方法
JP2003207490A (ja) * 2002-01-15 2003-07-25 Matsushita Electric Ind Co Ltd 高分子物質の抽出方法及びパターン形成材料の製造方法
US6966990B2 (en) * 2002-10-11 2005-11-22 Ferro Corporation Composite particles and method for preparing
US20060074010A1 (en) * 2004-10-01 2006-04-06 Ferro Corporation Method and apparatus for purifying pharmaceutical compositions using supercritical fluids
JP2008524235A (ja) * 2004-12-15 2008-07-10 キューエルティー ユーエスエー，インコーポレイテッド． オクトレオチド化合物の徐放性送達処方物

Also Published As

Publication number Publication date
EP2079767B1 (en) 2014-08-27
WO2008045516A1 (en) 2008-04-17
JP2010506965A (ja) 2010-03-04
ES2516695T3 (es) 2014-10-31
PT2079767E (pt) 2014-10-07
CA2666341A1 (en) 2008-04-17
CA2666341C (en) 2012-01-03
EP2079767A1 (en) 2009-07-22
JP5647788B2 (ja) 2015-01-07
EP2079767A4 (en) 2010-01-27
PL2079767T3 (pl) 2015-05-29
SI2079767T1 (sl) 2015-01-30
HK1136839A1 (en) 2010-07-09

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