DK2379501T3 - Fremgangsmåde til fremstilling af aktiverede estere - Google Patents

Fremgangsmåde til fremstilling af aktiverede estere

Info

Publication number
DK2379501T3
DK2379501T3 DK09802171.0T DK09802171T DK2379501T3 DK 2379501 T3 DK2379501 T3 DK 2379501T3 DK 09802171 T DK09802171 T DK 09802171T DK 2379501 T3 DK2379501 T3 DK 2379501T3
Authority
DK
Denmark
Prior art keywords
procedure
activated esters
manufacturing activated
manufacturing
esters
Prior art date
Application number
DK09802171.0T
Other languages
English (en)
Inventor
Antony Bigot
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of DK2379501T3 publication Critical patent/DK2379501T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK09802171.0T 2008-12-17 2009-12-15 Fremgangsmåde til fremstilling af aktiverede estere DK2379501T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0807090A FR2939795B1 (fr) 2008-12-17 2008-12-17 Procede de preparation d'esters actives
PCT/FR2009/052528 WO2010076474A1 (fr) 2008-12-17 2009-12-15 Procede de preparation d'esters actives

Publications (1)

Publication Number Publication Date
DK2379501T3 true DK2379501T3 (da) 2014-04-28

Family

ID=40614691

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09802171.0T DK2379501T3 (da) 2008-12-17 2009-12-15 Fremgangsmåde til fremstilling af aktiverede estere

Country Status (25)

Country Link
US (1) US8314244B2 (da)
EP (1) EP2379501B1 (da)
JP (1) JP5467111B2 (da)
KR (1) KR101645051B1 (da)
CN (1) CN102292318B (da)
AU (1) AU2009334689B2 (da)
BR (1) BRPI0922972B1 (da)
CA (1) CA2747105C (da)
CY (1) CY1115035T1 (da)
DK (1) DK2379501T3 (da)
ES (1) ES2459918T3 (da)
FR (1) FR2939795B1 (da)
HR (1) HRP20140368T1 (da)
IL (1) IL213525A (da)
ME (1) ME01827B (da)
MX (1) MX2011006624A (da)
MY (1) MY156761A (da)
PL (1) PL2379501T4 (da)
PT (1) PT2379501E (da)
RS (1) RS53267B (da)
RU (1) RU2506258C2 (da)
SG (1) SG172179A1 (da)
SI (1) SI2379501T1 (da)
SM (1) SMT201400061B (da)
WO (1) WO2010076474A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2963007B1 (fr) 2010-07-26 2013-04-05 Sanofi Aventis Derives anticancereux, leur preparation et leur application therapeutique
US11352325B2 (en) 2011-09-28 2022-06-07 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
US10436790B2 (en) 2011-09-28 2019-10-08 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
JP6774748B2 (ja) * 2014-08-13 2020-10-28 ウオーターズ・テクノロジーズ・コーポレイシヨン 強められたｍｓ信号を有するグリカンおよび他の生体分子の迅速蛍光タグ付け
DK3748340T3 (da) 2014-10-30 2022-04-19 Waters Technologies Corp Fremgangsmåder til hurtig præparering af mærkede glykosylaminer og til analyse af glykosylerede biomolekyler, som fremstiller samme
CN115536714B (zh) 2014-11-13 2026-04-24 沃特世科技公司 快速标记的n-聚糖的液相色谱校准方法
EP3472132A4 (en) 2016-06-21 2020-01-15 Waters Technologies Corporation FLUORESCENCE LABELING OF GLYCANS AND OTHER BIOMOLECULES BY REDUCING AMINATION FOR IMPROVED MASS SPECTROMETRY SIGNALS
EP3472621A4 (en) 2016-06-21 2020-03-04 Waters Technologies Corporation Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties
CN114839302A (zh) 2016-07-01 2022-08-02 沃特世科技公司 使用分子量截留过滤和过滤器上去糖基化从复杂基质快速制备标记的葡基胺的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5710101B2 (da) * 1972-10-24 1982-02-24
US5892057A (en) 1997-09-18 1999-04-06 Pierce Chemical Company Preparation of sulfo-N-hydroxysuccinimide salts
US5872261A (en) 1997-09-18 1999-02-16 Pierce Chemical Company Preparation of sulfo-N- hydroxy succinimide salts with intermediate formation of diester
JP2002316987A (ja) * 2001-04-20 2002-10-31 Sankyo Co Ltd ２−アルコキシベンゼン誘導体を含有する医薬
ES2361739T3 (es) * 2002-08-16 2011-06-21 Immunogen, Inc. Reticulantes con elevada reactividad y solubilidad y su uso en la preparación de conjugados para el suministro dirigido de fármacos de molécula pequeña.
WO2006054426A1 (ja) * 2004-10-29 2006-05-26 National University Corporation Toyama University 高蛍光量子収率型疎水性蛍光プローブ、それを用いる生体高分子検出法ならびに生体高分子間相互作用検出法
BRPI0517622A (pt) * 2004-11-09 2008-10-14 Ciba Sc Holding Ag imidas n-substituìdas como iniciadores de polimerização
WO2007008848A2 (en) * 2005-07-07 2007-01-18 Seattle Genetics, Inc. Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus

Also Published As

Publication number Publication date
MY156761A (en) 2016-03-31
JP2012512234A (ja) 2012-05-31
KR20110094311A (ko) 2011-08-23
CN102292318A (zh) 2011-12-21
CA2747105A1 (fr) 2010-07-08
KR101645051B1 (ko) 2016-08-02
PL2379501T3 (pl) 2014-07-31
MX2011006624A (es) 2011-11-04
US8314244B2 (en) 2012-11-20
EP2379501B1 (fr) 2014-01-22
SI2379501T1 (sl) 2014-05-30
US20110313168A1 (en) 2011-12-22
ME01827B (me) 2014-12-20
CN102292318B (zh) 2014-01-01
CY1115035T1 (el) 2016-12-14
PL2379501T4 (pl) 2014-12-31
SMT201400061B (it) 2014-07-07
SG172179A1 (en) 2011-07-28
WO2010076474A1 (fr) 2010-07-08
ES2459918T3 (es) 2014-05-12
EP2379501A1 (fr) 2011-10-26
FR2939795B1 (fr) 2010-12-17
RS53267B (sr) 2014-08-29
HRP20140368T1 (hr) 2014-06-20
IL213525A0 (en) 2011-07-31
HK1163664A1 (zh) 2012-09-14
BRPI0922972B1 (pt) 2021-06-01
IL213525A (en) 2014-11-30
BRPI0922972A8 (pt) 2018-02-06
AU2009334689B2 (en) 2015-10-08
FR2939795A1 (fr) 2010-06-18
RU2506258C2 (ru) 2014-02-10
RU2011129652A (ru) 2013-01-27
PT2379501E (pt) 2014-05-02
BRPI0922972A2 (pt) 2015-08-11
JP5467111B2 (ja) 2014-04-09
CA2747105C (fr) 2017-02-28
AU2009334689A1 (en) 2011-07-07

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