DK2090574T3 - Fremgangsmåde til fremstilling af stiripentolpartikler med defineret partikelstørrelse - Google Patents
Fremgangsmåde til fremstilling af stiripentolpartikler med defineret partikelstørrelseInfo
- Publication number
- DK2090574T3 DK2090574T3 DK09150741.8T DK09150741T DK2090574T3 DK 2090574 T3 DK2090574 T3 DK 2090574T3 DK 09150741 T DK09150741 T DK 09150741T DK 2090574 T3 DK2090574 T3 DK 2090574T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparing
- stiripentol
- particle size
- defined particle
- particles
- Prior art date
Links
- IBLNKMRFIPWSOY-FNORWQNLSA-N stiripentol Chemical compound CC(C)(C)C(O)\C=C\C1=CC=C2OCOC2=C1 IBLNKMRFIPWSOY-FNORWQNLSA-N 0.000 title abstract 4
- 229960001897 stiripentol Drugs 0.000 title abstract 4
- 239000002245 particle Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 239000003849 aromatic solvent Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0850413A FR2926552B1 (fr) | 2008-01-23 | 2008-01-23 | Procede de preparation de particules de stiripentol ayant une granulometrie definie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2090574T3 true DK2090574T3 (da) | 2012-01-16 |
Family
ID=39431071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09150741.8T DK2090574T3 (da) | 2008-01-23 | 2009-01-16 | Fremgangsmåde til fremstilling af stiripentolpartikler med defineret partikelstørrelse |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7750169B2 (da) |
| EP (1) | EP2090574B1 (da) |
| JP (1) | JP5571312B2 (da) |
| AT (1) | ATE525368T1 (da) |
| CA (1) | CA2651010A1 (da) |
| DK (1) | DK2090574T3 (da) |
| ES (1) | ES2373630T3 (da) |
| FR (1) | FR2926552B1 (da) |
| PL (1) | PL2090574T3 (da) |
| PT (1) | PT2090574E (da) |
| SI (1) | SI2090574T1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800168A (zh) * | 2015-04-08 | 2015-07-29 | 石家庄四药有限公司 | 司替戊醇干混悬剂及其制备方法 |
| WO2024141890A1 (en) | 2022-12-26 | 2024-07-04 | Kinedexe UK Limited | A stable ready to use suspension of stiripentol. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795893A (fr) * | 1972-02-28 | 1973-06-18 | Unicler | Derives de (methylene dioxy-3,4 phenyl)-1 dimethyl-4,4 pentene-1, leur preparation et leur application en therrapeutique |
| FR2253504A2 (en) | 1973-12-10 | 1975-07-04 | Unicler | 1-(3,4-Methylenedioxyphenyl)-4,4-dimethyl-pent-1-en-3-ol esters - modifiers of hexobarbital narcosis |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| JP2006104193A (ja) * | 2004-09-07 | 2006-04-20 | Mitsubishi Chemicals Corp | 微粒子化された物質の製造方法および微粒子化された物質 |
-
2008
- 2008-01-23 FR FR0850413A patent/FR2926552B1/fr active Active
-
2009
- 2009-01-16 AT AT09150741T patent/ATE525368T1/de active
- 2009-01-16 DK DK09150741.8T patent/DK2090574T3/da active
- 2009-01-16 EP EP09150741A patent/EP2090574B1/fr active Active
- 2009-01-16 SI SI200930125T patent/SI2090574T1/sl unknown
- 2009-01-16 PT PT09150741T patent/PT2090574E/pt unknown
- 2009-01-16 ES ES09150741T patent/ES2373630T3/es active Active
- 2009-01-16 PL PL09150741T patent/PL2090574T3/pl unknown
- 2009-01-20 CA CA002651010A patent/CA2651010A1/fr not_active Abandoned
- 2009-01-22 US US12/357,621 patent/US7750169B2/en active Active
- 2009-01-22 JP JP2009012254A patent/JP5571312B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20090187034A1 (en) | 2009-07-23 |
| PT2090574E (pt) | 2011-12-29 |
| US7750169B2 (en) | 2010-07-06 |
| FR2926552A1 (fr) | 2009-07-24 |
| EP2090574A1 (fr) | 2009-08-19 |
| JP2009173655A (ja) | 2009-08-06 |
| ATE525368T1 (de) | 2011-10-15 |
| SI2090574T1 (sl) | 2012-01-31 |
| PL2090574T3 (pl) | 2012-02-29 |
| EP2090574B1 (fr) | 2011-09-21 |
| FR2926552B1 (fr) | 2010-03-26 |
| ES2373630T3 (es) | 2012-02-07 |
| JP5571312B2 (ja) | 2014-08-13 |
| CA2651010A1 (fr) | 2009-07-23 |
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