DK2195295T3 - Fremgangsmåde til fremstilling af montelukastsyre i et ionisk væskemedie - Google Patents

Fremgangsmåde til fremstilling af montelukastsyre i et ionisk væskemedie

Info

Publication number
DK2195295T3
DK2195295T3 DK08838092.8T DK08838092T DK2195295T3 DK 2195295 T3 DK2195295 T3 DK 2195295T3 DK 08838092 T DK08838092 T DK 08838092T DK 2195295 T3 DK2195295 T3 DK 2195295T3
Authority
DK
Denmark
Prior art keywords
montelukastic
preparing
acid
liquid medium
ionic liquid
Prior art date
Application number
DK08838092.8T
Other languages
English (en)
Inventor
Chul-Hyun Park
Choong-Hahn Kim
Eun Jung Lim
Young Kil Chang
Gwan Sun Lee
Eun-Ju Park
Suk Man Jang
Jaeheon Lee
Original Assignee
Hanmi Science Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40549354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2195295(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hanmi Science Co Ltd filed Critical Hanmi Science Co Ltd
Application granted granted Critical
Publication of DK2195295T3 publication Critical patent/DK2195295T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK08838092.8T 2007-10-09 2008-10-01 Fremgangsmåde til fremstilling af montelukastsyre i et ionisk væskemedie DK2195295T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020070101486A KR101072896B1 (ko) 2007-10-09 2007-10-09 이온성 액체 매개체를 이용한 몬테루카스트산의 제조 방법
PCT/KR2008/005794 WO2009048236A1 (en) 2007-10-09 2008-10-01 Method for the preparation of montelukast acid in ionic liquid medium

Publications (1)

Publication Number Publication Date
DK2195295T3 true DK2195295T3 (da) 2013-05-06

Family

ID=40549354

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08838092.8T DK2195295T3 (da) 2007-10-09 2008-10-01 Fremgangsmåde til fremstilling af montelukastsyre i et ionisk væskemedie

Country Status (18)

Country Link
US (1) US8426599B2 (da)
EP (1) EP2195295B1 (da)
JP (1) JP5210389B2 (da)
KR (1) KR101072896B1 (da)
CN (1) CN101808998B (da)
AR (1) AR068755A1 (da)
CA (1) CA2701912C (da)
CL (1) CL2008002996A1 (da)
DK (1) DK2195295T3 (da)
ES (1) ES2398732T3 (da)
HR (1) HRP20130103T1 (da)
MX (1) MX2010001864A (da)
PE (2) PE20091369A1 (da)
PL (1) PL2195295T3 (da)
PT (1) PT2195295E (da)
RU (1) RU2436774C1 (da)
TW (1) TWI350284B (da)
WO (1) WO2009048236A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP1000425A2 (en) 2010-08-11 2012-03-28 Richter Gedeon Nyrt Process for the production of montelukast sodium
CN103570618A (zh) * 2013-09-30 2014-02-12 浙江车头制药股份有限公司 一种孟鲁司特钠盐的制备方法
CN105294556A (zh) * 2014-06-06 2016-02-03 上海迪赛诺化学制药有限公司 一种制备孟鲁司特酸的方法
EP3846792A4 (en) 2018-09-06 2022-10-12 Innopharmascreen Inc. METHODS AND COMPOSITIONS FOR TREATING ASTHMA OR PARKINSON'S DISEASE
KR102181155B1 (ko) * 2019-09-26 2020-11-20 대봉엘에스 주식회사 이온성 액체를 매개로 한 에피나코나졸의 신규 제조방법
CN111961083B (zh) * 2020-08-27 2022-11-25 鲁南制药集团股份有限公司 一种孟鲁司特钠中间体化合物
CN111892535B (zh) * 2020-08-27 2023-04-11 鲁南制药集团股份有限公司 一种孟鲁司特钠的合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0480717T3 (da) 1990-10-12 1999-02-08 Merck Frosst Canada Inc Umættede hydroxyalkylquinolinsyrer som leukotrienantagonister
MY107767A (en) * 1992-04-10 1996-06-15 Merck Frosst Canada Inc Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists
TW448160B (en) 1993-12-28 2001-08-01 Merck & Co Inc Novel dicyclohexylamine salt and process for the preparation of leukotriene antagonists
US5523477A (en) * 1995-01-23 1996-06-04 Merck & Co., Inc. Process for the preparation of 1-(thiomethyl)-cyclopropaneacetic acid
KR20060117356A (ko) * 2004-01-30 2006-11-16 테바 파마슈티컬 인더스트리즈 리미티드 몬테루카스트 유리산 다형체
US7547787B2 (en) * 2004-04-21 2009-06-16 Teva Pharmaceutical Industries Ltd. Processes for preparing montelukast sodium
JP2006089463A (ja) * 2004-08-24 2006-04-06 Sumitomo Chemical Co Ltd アリールエーテル類の製造方法
WO2006064269A2 (en) 2004-12-17 2006-06-22 Cipla Limited Salts of leukotriene antagonist montelukast
GB0500029D0 (en) * 2005-01-04 2005-02-09 Univ Belfast Basic ionic liquids
AU2006302237C1 (en) 2005-10-07 2012-11-08 The University Of Alabama Multi-functional ionic liquid compositions
EP1783117A1 (en) 2005-11-04 2007-05-09 Esteve Quimica, S.A. Process for the preparation of a leukotriene antagonist and intermediates thereof
ES2403067T3 (es) 2005-12-13 2013-05-13 Msn Laboratories Limited Un procedimiento mejorado para la preparación de montelukast y sus sales farmaceúticamente aceptables
CA2632954A1 (en) * 2005-12-23 2007-06-28 Glade Organics Private Limited An improved process for the manufacture of montelukast sodium
IL181607A0 (en) * 2006-02-27 2007-07-04 Chemagis Ltd Novel process for preparing montelukast and salts thereof
KR100774088B1 (ko) 2006-12-14 2007-11-06 한미약품 주식회사 몬테루카스트의 제조방법 및 이에 사용되는 중간체

Also Published As

Publication number Publication date
TW200920737A (en) 2009-05-16
JP5210389B2 (ja) 2013-06-12
CN101808998A (zh) 2010-08-18
CA2701912A1 (en) 2009-04-16
AR068755A1 (es) 2009-12-02
KR101072896B1 (ko) 2011-10-17
EP2195295B1 (en) 2013-01-23
ES2398732T3 (es) 2013-03-21
TWI350284B (en) 2011-10-11
PE20091369A1 (es) 2009-10-01
CL2008002996A1 (es) 2009-04-13
PT2195295E (pt) 2013-02-28
EP2195295A1 (en) 2010-06-16
CN101808998B (zh) 2012-10-24
RU2436774C1 (ru) 2011-12-20
PL2195295T3 (pl) 2013-06-28
US20110105757A1 (en) 2011-05-05
JP2011500555A (ja) 2011-01-06
US8426599B2 (en) 2013-04-23
KR20090036349A (ko) 2009-04-14
WO2009048236A1 (en) 2009-04-16
MX2010001864A (es) 2010-03-15
EP2195295A4 (en) 2011-04-13
PE20131219A1 (es) 2013-11-16
CA2701912C (en) 2013-04-02
HRP20130103T1 (hr) 2013-02-28

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