DK214480A - Fremgangsmaade til fremstilling af 2-(pyrimidinylamino)-1,3-diaza-2-cycloalkenforbindelser deres tautomere forbindelser og syreadditionssalte deraf - Google Patents
Fremgangsmaade til fremstilling af 2-(pyrimidinylamino)-1,3-diaza-2-cycloalkenforbindelser deres tautomere forbindelser og syreadditionssalte derafInfo
- Publication number
- DK214480A DK214480A DK214480A DK214480A DK214480A DK 214480 A DK214480 A DK 214480A DK 214480 A DK214480 A DK 214480A DK 214480 A DK214480 A DK 214480A DK 214480 A DK214480 A DK 214480A
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- cycloalken
- pyrimidinylamino
- diaza
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH466979 | 1979-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK214480A true DK214480A (da) | 1980-11-19 |
Family
ID=4280399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK214480A DK214480A (da) | 1979-05-18 | 1980-05-16 | Fremgangsmaade til fremstilling af 2-(pyrimidinylamino)-1,3-diaza-2-cycloalkenforbindelser deres tautomere forbindelser og syreadditionssalte deraf |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0019811A1 (fr) |
| JP (1) | JPS55154971A (fr) |
| KR (1) | KR830002757A (fr) |
| AR (1) | AR228256A1 (fr) |
| AU (1) | AU5848480A (fr) |
| DD (1) | DD150609A5 (fr) |
| DK (1) | DK214480A (fr) |
| ES (1) | ES8104279A1 (fr) |
| FI (1) | FI801600A7 (fr) |
| GB (1) | GB2052487B (fr) |
| GR (1) | GR68453B (fr) |
| IE (1) | IE49803B1 (fr) |
| IL (1) | IL60086A (fr) |
| MA (1) | MA18829A1 (fr) |
| NO (1) | NO801469L (fr) |
| NZ (1) | NZ193730A (fr) |
| OA (1) | OA06533A (fr) |
| PL (1) | PL224313A1 (fr) |
| PT (1) | PT71251A (fr) |
| ZA (1) | ZA802909B (fr) |
| ZW (1) | ZW11880A1 (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4507146A (en) * | 1982-12-28 | 1985-03-26 | Ciba-Geigy Corporation | 2,4-Diamino-6-halo-5-trifluoromethylpyrimidines having herbicidal activity |
| DE3829469A1 (de) * | 1988-08-31 | 1990-03-01 | Bayer Ag | Verfahren zur herstellung von substituierten n-azinyl-n'-sulfonyl-isothioharnstoffen und n-azinyl-iminodithiokohlensaeure-s,s-diester als zwischenprodukte zu ihrer herstellung |
| EP0954316A4 (fr) * | 1997-09-03 | 2002-02-13 | Lilly Co Eli | Derives de pyrimidine |
| AU2001290912A1 (en) | 2000-09-15 | 2002-03-26 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US6660731B2 (en) | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US7473691B2 (en) | 2000-09-15 | 2009-01-06 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| BR0116493A (pt) | 2000-12-21 | 2003-09-30 | Vertex Pharma | Compostos de pirazol úteis como inibidores de proteìna cinase |
| EP1363638A4 (fr) * | 2001-01-31 | 2010-01-06 | Lundbeck & Co As H | Utilisation d'antagonistes du recepteur gal3 dans le traitement de la depression et/ou de l'anxiete et composes utiles dans de telles methodes |
| CA2479036A1 (fr) | 2002-03-13 | 2003-09-18 | Euro-Celtique S.A. | Pyrimidines substituees par aryle et utilisation associee |
| AU2003214110A1 (en) * | 2002-03-15 | 2003-09-29 | Ciba Specialty Chemicals Holding Inc. | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces |
| US20040009981A1 (en) | 2002-03-15 | 2004-01-15 | David Bebbington | Compositions useful as inhibitors of protein kinases |
| MY141867A (en) | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
| MXPA05001367A (es) | 2002-08-02 | 2005-04-28 | Vertex Pharma | Composiciones de pirazol utiles como inhibidores de gsk-3. |
| WO2004072029A2 (fr) | 2003-02-06 | 2004-08-26 | Vertex Pharmaceuticals Incorporated | Compositions utiles en tant qu'inhibiteurs de proteine kinases |
| US7737151B2 (en) | 2005-08-18 | 2010-06-15 | Vertex Pharmaceuticals Incorporated | Pyrazine kinase inhibitors |
| JP5249770B2 (ja) | 2005-11-03 | 2013-07-31 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼインヒビターとして有用なアミノピリジン |
| CA2668429A1 (fr) | 2006-11-02 | 2008-05-15 | Vertex Pharmaceuticals Incorporated | Aminopyridines et aminopyrimidines utiles en tant qu'inhibiteurs de proteines kinases |
| NZ577768A (en) | 2006-12-19 | 2012-01-12 | Vertex Pharma | Aminopyrimidines useful as inhibitors of protein kinases |
| NZ579483A (en) | 2007-03-09 | 2012-07-27 | Vertex Pharma | Aminopyridines useful as inhibitors of protein kinases |
| CN101663295B (zh) | 2007-03-09 | 2014-11-05 | 沃泰克斯药物股份有限公司 | 可用作蛋白激酶抑制剂的氨基嘧啶类化合物 |
| JP5393489B2 (ja) | 2007-03-09 | 2014-01-22 | バーテックス ファーマシューティカルズ インコーポレイテッド | 蛋白キナーゼの阻害剤として有用なアミノピリミジン |
| MX2009011059A (es) | 2007-04-13 | 2009-11-26 | Vertex Pharma | Aminopirimidinas utiles como inhibidores de cinasas. |
| AU2008247594A1 (en) | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as kinase inhibitors |
| WO2008137619A2 (fr) | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Thiazoles et pyrazoles qui s'utilisent comme inhibiteurs de kinase |
| WO2009018415A1 (fr) | 2007-07-31 | 2009-02-05 | Vertex Pharmaceuticals Incorporated | Procédé de préparation de la 5-fluoro-1h-pyrazolo[3,4-b]pyridin-3-amine et des dérivés de celle-ci |
| AU2009288200A1 (en) | 2008-09-03 | 2010-03-11 | Vertex Pharmaceuticals Incorporated | Co-crystals and pharmaceutical formulations comprising the same |
| UY32306A (es) * | 2008-12-09 | 2010-07-30 | Gilead Sciences Inc | Derivados de pteridinona y pirimidinodiazepinona y composiciones farmacéuticas que modulan en forma selectiva los receptores tipo toll, métodos y usos |
| KR102328682B1 (ko) * | 2018-08-27 | 2021-11-18 | 주식회사 대웅제약 | 신규한 헤테로사이클릭아민 유도체 및 이를 포함하는 약학 조성물 |
| EP4243826A1 (fr) * | 2020-11-12 | 2023-09-20 | 3Z Ehf | Nouveaux traitements du trouble du déficit de l'attention/hyperactivité |
| CN121494792B (zh) * | 2026-01-14 | 2026-06-30 | 山东国邦药业有限公司 | 一种5-甲氧基-4,6-二羟基嘧啶的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE754832A (fr) * | 1969-08-14 | 1971-02-15 | Beecham Group Ltd | Iminazolines |
-
1980
- 1980-05-05 MA MA19025A patent/MA18829A1/fr unknown
- 1980-05-13 DD DD80221082A patent/DD150609A5/de unknown
- 1980-05-14 ES ES491514A patent/ES8104279A1/es not_active Expired
- 1980-05-15 IL IL60086A patent/IL60086A/xx unknown
- 1980-05-15 NZ NZ193730A patent/NZ193730A/xx unknown
- 1980-05-16 AU AU58484/80A patent/AU5848480A/en not_active Abandoned
- 1980-05-16 GB GB8016309A patent/GB2052487B/en not_active Expired
- 1980-05-16 PT PT71251A patent/PT71251A/pt unknown
- 1980-05-16 GR GR61963A patent/GR68453B/el unknown
- 1980-05-16 ZA ZA00802909A patent/ZA802909B/xx unknown
- 1980-05-16 ZW ZW118/80A patent/ZW11880A1/xx unknown
- 1980-05-16 FI FI801600A patent/FI801600A7/fi not_active Application Discontinuation
- 1980-05-16 IE IE1023/80A patent/IE49803B1/en unknown
- 1980-05-16 NO NO801469A patent/NO801469L/no unknown
- 1980-05-16 EP EP80102724A patent/EP0019811A1/fr not_active Withdrawn
- 1980-05-16 DK DK214480A patent/DK214480A/da not_active Application Discontinuation
- 1980-05-17 KR KR1019800001944A patent/KR830002757A/ko active Pending
- 1980-05-17 PL PL22431380A patent/PL224313A1/xx unknown
- 1980-05-17 JP JP6586380A patent/JPS55154971A/ja active Pending
- 1980-05-17 OA OA57113A patent/OA06533A/fr unknown
- 1980-05-19 AR AR281109A patent/AR228256A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| IE49803B1 (en) | 1985-12-25 |
| PL224313A1 (fr) | 1981-02-13 |
| ES491514A0 (es) | 1981-04-16 |
| GB2052487A (en) | 1981-01-28 |
| JPS55154971A (en) | 1980-12-02 |
| ES8104279A1 (es) | 1981-04-16 |
| GB2052487B (en) | 1983-05-11 |
| ZA802909B (en) | 1981-05-27 |
| ZW11880A1 (en) | 1980-12-17 |
| IL60086A0 (en) | 1980-07-31 |
| EP0019811A1 (fr) | 1980-12-10 |
| PT71251A (en) | 1980-06-01 |
| MA18829A1 (fr) | 1980-12-31 |
| NO801469L (no) | 1980-11-19 |
| AR228256A1 (es) | 1983-02-15 |
| IL60086A (en) | 1984-03-30 |
| NZ193730A (en) | 1982-12-21 |
| KR830002757A (ko) | 1983-05-30 |
| IE801023L (en) | 1980-11-18 |
| DD150609A5 (de) | 1981-09-09 |
| AU5848480A (en) | 1980-11-20 |
| GR68453B (fr) | 1981-12-30 |
| FI801600A7 (fi) | 1981-01-01 |
| OA06533A (fr) | 1981-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK462380A (da) | Analogifremgangsmaade til fremstilling af 2,4-diaminoquinazolin-forbindelser eller syreadditionssalte deraf | |
| DK178379A (da) | Fremgangsmaade til fremstilling af n-substituerede moranolinderivater eller syreadditionssalte deraf | |
| DK408580A (da) | Fremgangsmaade til fremstilling af 1,8-naphthydridinforbindelser | |
| FI801600A7 (fi) | Menetelmiä pyrimidiiniyhdisteiden valmistamiseksi. | |
| DK344280A (da) | Fremgangsmaade til fremstilling af aminopropoxyarylderivater | |
| DK493083D0 (da) | Fremgangsmaade til fremstilling af 4-oxo-1,4-dihydfremgangsmade til fremstilling af 4-oxo-1,4-dihydronicotinsyrederivater eller salte deraf ronicotinsyrederivater eller salte deraf | |
| DK325078A (da) | Fremgangsmaade til fremstilling af 5-substitueret-1,2dihydro-3h-pyrrolo (1,2a)-pyrrol-1-carboxylsyrer af deres tilsvarende nitriler | |
| DK163580C (da) | Analogifremgangsmaade til fremstilling af cyclohexancarboxylsyrederivater | |
| DK320680A (da) | Fremgangsmaade til fremstilling af fluorerede beta-alanin-derivater | |
| DK134580A (da) | Fremgangsmaade til fremstilling af 2,6-diaminonebulariner eller syreadditionssalte deraf | |
| DK365980A (da) | Fremgangsmaade til fremstilling af 7-betaaminothiadiazolylacetylamino-3-cephem-4-carboxylsyreforbindelser eller salte deraf | |
| DK152754C (da) | Analogifremgangsmaade til fremstilling af 1-acyl-8-(3-amino-2-hydroxypropoxy)-1,2,3,4-tetrahydroquinoliner eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK289080A (da) | Fremgangsmaade til spaltning af d,1 2-(6-methoxy2-naphthyl) propionsyre | |
| DK172479A (da) | Fremgangsmaade til fremstilling af n-alkenylmoranolinderivater eller syreadditionssalte deraf | |
| DK455980A (da) | Analogifremgangsmaade til fremstilling af spiroimidazolonforbindelser eller syreaddiionssalte deraf | |
| DK516480A (da) | Fremgangsmaade til fremstilling af 2-amino-ethanol-derivater eller syreadditionssalte deraf | |
| DK234182A (da) | Fremgangsmaade til fremstilling af heterocyclisk substitueredeamidoximer eller syreadditionssalte deraf | |
| FI811610A7 (fi) | Menetelmä 4-(3- jodipropargyylioksi)pyrimidiinijohdannaisten valmistamiseksi. | |
| DK229580A (da) | Fremgangsmaade til fremstilling af guanidinderivater deres tautomere forbindelser og salte | |
| DK258180A (da) | Fremgangsmaade til fremstilling af pyridylaminotriazoler eller syreadditionssalte deraf | |
| DK146537C (da) | Analogifremgangsmaade til fremstilling af spiro-quinolon-hydantoinforbindelser eller syreadditionssalte deraf | |
| DK154880A (da) | Fremgangsmaade til fremstilling af derivater af 6beta-amidinopenicillansyre | |
| DK129380A (da) | Fremgangsmaade til fremstilling af 6,7-dialkoxy-1-piperidinophthalazin-forbindelser eller syreadditionssalte deraf | |
| DK509780A (da) | Fremgangsmaade til fremstilling af anti-tumoraktive salte | |
| DK198280A (da) | Fremgangsmaade til fremstilling af 6-(substitueret amino)-3-pyridazinylhydraziner eller salte deraf |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn | ||
| AHS | Application shelved for other reasons than non-payment |