DK2182945T3 - PROCEDURE TO COMBAT PESTS WITH ANIMALS - Google Patents

PROCEDURE TO COMBAT PESTS WITH ANIMALS Download PDF

Info

Publication number: DK2182945T3
Authority: DK; Denmark
Prior art keywords: compounds; compound; methyl; dihydro; benzamide
Prior art date: 2007-06-27

Application number

DK08771978.7T

Other languages

Danish (da)

English (en)

Inventor

George Philip Lahm

Jeffrey Keith Long

Ming Xu

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-27

Filing date

2008-06-26

Publication date

2015-11-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40003056&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2182945(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-06-26 Application filed by Du Pont filed Critical Du Pont

2015-11-16 Application granted granted Critical

2015-11-16 Publication of DK2182945T3 publication Critical patent/DK2182945T3/en

Links

241001465754 Metazoa Species 0.000 title claims description 30
238000000034 method Methods 0.000 title claims description 16
150000001875 compounds Chemical class 0.000 claims description 93
241000607479 Yersinia pestis Species 0.000 claims description 36
230000003071 parasitic effect Effects 0.000 claims description 24
-1 3,5-dichlorophenyl Chemical group 0.000 claims description 20
KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 claims description 16
150000003839 salts Chemical class 0.000 claims description 12
241000282326 Felis catus Species 0.000 claims description 7
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 6
150000001204 N-oxides Chemical class 0.000 claims description 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 7
150000001412 amines Chemical class 0.000 claims 1
125000004205 trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 claims 1
239000000203 mixture Substances 0.000 description 46
239000005660 Abamectin Substances 0.000 description 13
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 12
238000012360 testing method Methods 0.000 description 12
241000238876 Acari Species 0.000 description 11
241000258924 Ctenocephalides felis Species 0.000 description 11
241000258242 Siphonaptera Species 0.000 description 11
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical class C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 description 10
238000009472 formulation Methods 0.000 description 10
239000004480 active ingredient Substances 0.000 description 9
125000000623 heterocyclic group Chemical group 0.000 description 9
230000003115 biocidal effect Effects 0.000 description 8
230000000694 effects Effects 0.000 description 8
239000000575 pesticide Substances 0.000 description 8
241000282472 Canis lupus familiaris Species 0.000 description 6
239000003242 anti bacterial agent Substances 0.000 description 6
229940088710 antibiotic agent Drugs 0.000 description 6
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 description 5
206010061217 Infestation Diseases 0.000 description 5
239000000654 additive Substances 0.000 description 5
239000000969 carrier Substances 0.000 description 5
239000003795 chemical substances by application Substances 0.000 description 5
GCKZANITAMOIAR-XWVCPFKXSA-N dsstox_cid_14566 Chemical compound [O-]C(=O)C1=CC=CC=C1.C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H]([NH2+]C)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 GCKZANITAMOIAR-XWVCPFKXSA-N 0.000 description 5
244000045947 parasite Species 0.000 description 5
AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 description 4
239000008280 blood Substances 0.000 description 4
210000004369 blood Anatomy 0.000 description 4
239000012141 concentrate Substances 0.000 description 4
229940074076 glycerol formal Drugs 0.000 description 4
229960002418 ivermectin Drugs 0.000 description 4
238000004519 manufacturing process Methods 0.000 description 4
230000000590 parasiticidal effect Effects 0.000 description 4
238000002360 preparation method Methods 0.000 description 4
230000008569 process Effects 0.000 description 4
SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 description 3
239000005894 Emamectin Substances 0.000 description 3
229920002472 Starch Polymers 0.000 description 3
230000009471 action Effects 0.000 description 3
244000000054 animal parasite Species 0.000 description 3
230000002141 anti-parasite Effects 0.000 description 3
239000003096 antiparasitic agent Substances 0.000 description 3
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 3
229910052799 carbon Inorganic materials 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical class OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
239000003085 diluting agent Substances 0.000 description 3
NYPJDWWKZLNGGM-UHFFFAOYSA-N fenvalerate Aalpha Natural products C=1C=C(Cl)C=CC=1C(C(C)C)C(=O)OC(C#N)C(C=1)=CC=CC=1OC1=CC=CC=C1 NYPJDWWKZLNGGM-UHFFFAOYSA-N 0.000 description 3
230000036541 health Effects 0.000 description 3
230000005764 inhibitory process Effects 0.000 description 3
FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 description 3
YZBLFMPOMVTDJY-CBYMMZEQSA-N moxidectin Chemical compound O1[C@H](C(\C)=C\C(C)C)[C@@H](C)C(=N/OC)\C[C@@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 YZBLFMPOMVTDJY-CBYMMZEQSA-N 0.000 description 3
229960004816 moxidectin Drugs 0.000 description 3
230000000361 pesticidal effect Effects 0.000 description 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 3
229920002451 polyvinyl alcohol Polymers 0.000 description 3
235000019422 polyvinyl alcohol Nutrition 0.000 description 3
JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 3
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 3
239000007787 solid Substances 0.000 description 3
AYIRNRDRBQJXIF-NXEZZACHSA-N (-)-Florfenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)C=C1 AYIRNRDRBQJXIF-NXEZZACHSA-N 0.000 description 2
NHQDETIJWKXCTC-UHFFFAOYSA-N 3-chloroperbenzoic acid Chemical compound OOC(=O)C1=CC=CC(Cl)=C1 NHQDETIJWKXCTC-UHFFFAOYSA-N 0.000 description 2
IBSREHMXUMOFBB-JFUDTMANSA-N 5u8924t11h Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C(C)C)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 IBSREHMXUMOFBB-JFUDTMANSA-N 0.000 description 2
SPFYMRJSYKOXGV-UHFFFAOYSA-N Baytril Chemical compound C1CN(CC)CCN1C(C(=C1)F)=CC2=C1C(=O)C(C(O)=O)=CN2C1CC1 SPFYMRJSYKOXGV-UHFFFAOYSA-N 0.000 description 2
239000005711 Benzoic acid Substances 0.000 description 2
239000004322 Butylated hydroxytoluene Substances 0.000 description 2
NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
229930186147 Cephalosporin Natural products 0.000 description 2
241000490513 Ctenocephalides canis Species 0.000 description 2
QMLVECGLEOSESV-RYUDHWBXSA-N Danofloxacin Chemical compound C([C@@H]1C[C@H]2CN1C)N2C(C(=CC=1C(=O)C(C(O)=O)=C2)F)=CC=1N2C1CC1 QMLVECGLEOSESV-RYUDHWBXSA-N 0.000 description 2
241001481695 Dermanyssus gallinae Species 0.000 description 2
IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
229930182555 Penicillin Natural products 0.000 description 2
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical class OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
239000004372 Polyvinyl alcohol Substances 0.000 description 2
241000718000 Pulex irritans Species 0.000 description 2
241001481703 Rhipicephalus <genus> Species 0.000 description 2
241000331598 Trombiculidae Species 0.000 description 2
GUARTUJKFNAVIK-QPTWMBCESA-N Tulathromycin A Chemical compound C1[C@](OC)(C)[C@@](CNCCC)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)NC[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C GUARTUJKFNAVIK-QPTWMBCESA-N 0.000 description 2
241000353223 Xenopsylla cheopis Species 0.000 description 2
229950008167 abamectin Drugs 0.000 description 2
229960002669 albendazole Drugs 0.000 description 2
HXHWSAZORRCQMX-UHFFFAOYSA-N albendazole Chemical compound CCCSC1=CC=C2NC(NC(=O)OC)=NC2=C1 HXHWSAZORRCQMX-UHFFFAOYSA-N 0.000 description 2
239000000783 alginic acid Substances 0.000 description 2
235000010443 alginic acid Nutrition 0.000 description 2
229920000615 alginic acid Polymers 0.000 description 2
229960001126 alginic acid Drugs 0.000 description 2
150000004781 alginic acids Chemical class 0.000 description 2
LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 description 2
229960003022 amoxicillin Drugs 0.000 description 2
230000002924 anti-infective effect Effects 0.000 description 2
229960005475 antiinfective agent Drugs 0.000 description 2
239000003963 antioxidant agent Substances 0.000 description 2
230000003078 antioxidant effect Effects 0.000 description 2
125000004429 atom Chemical group 0.000 description 2
235000010233 benzoic acid Nutrition 0.000 description 2
239000011230 binding agent Substances 0.000 description 2
235000010354 butylated hydroxytoluene Nutrition 0.000 description 2
229940095259 butylated hydroxytoluene Drugs 0.000 description 2
DUEPRVBVGDRKAG-UHFFFAOYSA-N carbofuran Chemical compound CNC(=O)OC1=CC=CC2=C1OC(C)(C)C2 DUEPRVBVGDRKAG-UHFFFAOYSA-N 0.000 description 2
239000001913 cellulose Substances 0.000 description 2
229920002678 cellulose Polymers 0.000 description 2
235000010980 cellulose Nutrition 0.000 description 2
229940124587 cephalosporin Drugs 0.000 description 2
150000001780 cephalosporins Chemical class 0.000 description 2
229960004385 danofloxacin Drugs 0.000 description 2
230000003467 diminishing effect Effects 0.000 description 2
QLFZZSKTJWDQOS-YDBLARSUSA-N doramectin Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C3CCCCC3)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C QLFZZSKTJWDQOS-YDBLARSUSA-N 0.000 description 2
229960003997 doramectin Drugs 0.000 description 2
239000000975 dye Substances 0.000 description 2
239000000839 emulsion Substances 0.000 description 2
229960000740 enrofloxacin Drugs 0.000 description 2
238000001704 evaporation Methods 0.000 description 2
230000008020 evaporation Effects 0.000 description 2
238000000855 fermentation Methods 0.000 description 2
230000004151 fermentation Effects 0.000 description 2
239000000945 filler Substances 0.000 description 2
235000013305 food Nutrition 0.000 description 2
230000037406 food intake Effects 0.000 description 2
239000000499 gel Substances 0.000 description 2
230000014509 gene expression Effects 0.000 description 2
229940088597 hormone Drugs 0.000 description 2
239000005556 hormone Substances 0.000 description 2
230000002209 hydrophobic effect Effects 0.000 description 2
208000015181 infectious disease Diseases 0.000 description 2
239000002917 insecticide Substances 0.000 description 2
150000002547 isoxazolines Chemical class 0.000 description 2
239000002949 juvenile hormone Substances 0.000 description 2
239000003120 macrolide antibiotic agent Substances 0.000 description 2
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
239000012528 membrane Substances 0.000 description 2
LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 2
239000000049 pigment Substances 0.000 description 2
229920002689 polyvinyl acetate Polymers 0.000 description 2
102000004169 proteins and genes Human genes 0.000 description 2
108090000623 proteins and genes Proteins 0.000 description 2
230000009467 reduction Effects 0.000 description 2
230000000630 rising effect Effects 0.000 description 2
AFJYYKSVHJGXSN-KAJWKRCWSA-N selamectin Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1C(/C)=C/C[C@@H](O[C@]2(O[C@@H]([C@@H](C)CC2)C2CCCCC2)C2)C[C@@H]2OC(=O)[C@@H]([C@]23O)C=C(C)C(=N\O)/[C@H]3OC\C2=C/C=C/[C@@H]1C AFJYYKSVHJGXSN-KAJWKRCWSA-N 0.000 description 2
229960002245 selamectin Drugs 0.000 description 2
241000894007 species Species 0.000 description 2
238000001228 spectrum Methods 0.000 description 2
239000008107 starch Substances 0.000 description 2
235000019698 starch Nutrition 0.000 description 2
235000000346 sugar Nutrition 0.000 description 2
229910052717 sulfur Inorganic materials 0.000 description 2
239000004094 surface-active agent Substances 0.000 description 2
XLNZEKHULJKQBA-UHFFFAOYSA-N terbufos Chemical compound CCOP(=S)(OCC)SCSC(C)(C)C XLNZEKHULJKQBA-UHFFFAOYSA-N 0.000 description 2
229960000223 tilmicosin Drugs 0.000 description 2
JTSDBFGMPLKDCD-XVFHVFLVSA-N tilmicosin Chemical compound O([C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CCN1C[C@H](C)C[C@H](C)C1)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@@H]1O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]1O JTSDBFGMPLKDCD-XVFHVFLVSA-N 0.000 description 2
229960002859 tulathromycin Drugs 0.000 description 2
ZCVAOQKBXKSDMS-AQYZNVCMSA-N (+)-trans-allethrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC1C(C)=C(CC=C)C(=O)C1 ZCVAOQKBXKSDMS-AQYZNVCMSA-N 0.000 description 1
SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 1
ZXQYGBMAQZUVMI-RDDWSQKMSA-N (1S)-cis-(alphaR)-cyhalothrin Chemical compound CC1(C)[C@H](\C=C(/Cl)C(F)(F)F)[C@@H]1C(=O)O[C@@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 ZXQYGBMAQZUVMI-RDDWSQKMSA-N 0.000 description 1
YWKJNRNSJKEFMK-PQFQYKRASA-N (6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Chemical compound N([C@@H]1C(N2C(=C(C[N+]=3C=4CCCCC=4C=CC=3)CS[C@@H]21)C([O-])=O)=O)C(=O)\C(=N/OC)C1=CSC(N)=N1 YWKJNRNSJKEFMK-PQFQYKRASA-N 0.000 description 1
WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
IAKOZHOLGAGEJT-UHFFFAOYSA-N 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-Ethane Chemical compound C1=CC(OC)=CC=C1C(C(Cl)(Cl)Cl)C1=CC=C(OC)C=C1 IAKOZHOLGAGEJT-UHFFFAOYSA-N 0.000 description 1
NFGXHKASABOEEW-UHFFFAOYSA-N 1-methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate Chemical compound COC(C)(C)CCCC(C)CC=CC(C)=CC(=O)OC(C)C NFGXHKASABOEEW-UHFFFAOYSA-N 0.000 description 1
FMTFEIJHMMQUJI-NJAFHUGGSA-N 102130-98-3 Natural products CC=CCC1=C(C)[C@H](CC1=O)OC(=O)[C@@H]1[C@@H](C=C(C)C)C1(C)C FMTFEIJHMMQUJI-NJAFHUGGSA-N 0.000 description 1
238000005160 1H NMR spectroscopy Methods 0.000 description 1
125000004206 2,2,2-trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 description 1
FSVJFNAIGNNGKK-UHFFFAOYSA-N 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one Chemical class C1C(C2=CC=CC=C2CC2)N2C(=O)CN1C(=O)C1CCCCC1 FSVJFNAIGNNGKK-UHFFFAOYSA-N 0.000 description 1
LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
UMZCLZPXPCNKML-UHFFFAOYSA-N 2h-imidazo[4,5-d][1,3]thiazole Chemical class C1=NC2=NCSC2=N1 UMZCLZPXPCNKML-UHFFFAOYSA-N 0.000 description 1
WEQPBCSPRXFQQS-UHFFFAOYSA-N 4,5-dihydro-1,2-oxazole Chemical compound C1CC=NO1 WEQPBCSPRXFQQS-UHFFFAOYSA-N 0.000 description 1
QOVTVIYTBRHADL-UHFFFAOYSA-N 4-amino-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide Chemical compound NC1=CC(C(Cl)=C(Cl)Cl)=C(S(N)(=O)=O)C=C1S(N)(=O)=O QOVTVIYTBRHADL-UHFFFAOYSA-N 0.000 description 1
QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
229920001817 Agar Polymers 0.000 description 1
GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
241000238682 Amblyomma americanum Species 0.000 description 1
241001480748 Argas Species 0.000 description 1
241000238888 Argasidae Species 0.000 description 1
241000193388 Bacillus thuringiensis Species 0.000 description 1
241000283690 Bos taurus Species 0.000 description 1
JFLRKDZMHNBDQS-UCQUSYKYSA-N CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C Chemical compound CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C JFLRKDZMHNBDQS-UCQUSYKYSA-N 0.000 description 1
VEDTXTNSFWUXGQ-UHFFFAOYSA-N Carbophenothion Chemical compound CCOP(=S)(OCC)SCSC1=CC=C(Cl)C=C1 VEDTXTNSFWUXGQ-UHFFFAOYSA-N 0.000 description 1
229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
RAPBNVDSDCTNRC-UHFFFAOYSA-N Chlorobenzilate Chemical compound C=1C=C(Cl)C=CC=1C(O)(C(=O)OCC)C1=CC=C(Cl)C=C1 RAPBNVDSDCTNRC-UHFFFAOYSA-N 0.000 description 1
239000005944 Chlorpyrifos Substances 0.000 description 1
239000004099 Chlortetracycline Substances 0.000 description 1
241001307956 Chorioptes bovis Species 0.000 description 1
HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 description 1
239000005749 Copper compound Substances 0.000 description 1
JJLJMEJHUUYSSY-UHFFFAOYSA-L Copper hydroxide Chemical compound [OH-].[OH-].[Cu+2] JJLJMEJHUUYSSY-UHFFFAOYSA-L 0.000 description 1
239000005750 Copper hydroxide Substances 0.000 description 1
229920002261 Corn starch Polymers 0.000 description 1
241000258922 Ctenocephalides Species 0.000 description 1
239000005946 Cypermethrin Substances 0.000 description 1
239000005891 Cyromazine Substances 0.000 description 1
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
241001480819 Dermacentor andersoni Species 0.000 description 1
241001480793 Dermacentor variabilis Species 0.000 description 1
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical class OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
239000005893 Diflubenzuron Substances 0.000 description 1
239000005947 Dimethoate Substances 0.000 description 1
241000196324 Embryophyta Species 0.000 description 1
239000005895 Esfenvalerate Substances 0.000 description 1
PNKUSGQVOMIXLU-UHFFFAOYSA-N Formamidine Chemical class NC=N PNKUSGQVOMIXLU-UHFFFAOYSA-N 0.000 description 1
108010010803 Gelatin Proteins 0.000 description 1
241000238631 Hexapoda Species 0.000 description 1
241000238703 Ixodes scapularis Species 0.000 description 1
241000238889 Ixodidae Species 0.000 description 1
BPFYOAJNDMUVBL-UHFFFAOYSA-N LSM-5799 Chemical compound C1CN(C)CCN1C1=C(F)C=C2C(=O)C(C(O)=O)=CN3N(C)COC1=C32 BPFYOAJNDMUVBL-UHFFFAOYSA-N 0.000 description 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
235000010643 Leucaena leucocephala Nutrition 0.000 description 1
240000007472 Leucaena leucocephala Species 0.000 description 1
HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 description 1
235000019759 Maize starch Nutrition 0.000 description 1
239000005949 Malathion Substances 0.000 description 1
241000124008 Mammalia Species 0.000 description 1
229930195725 Mannitol Natural products 0.000 description 1
241001481698 Mesostigmata Species 0.000 description 1
239000005916 Methomyl Substances 0.000 description 1
RAOCRURYZCVHMG-UHFFFAOYSA-N N-(6-propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester Chemical compound CCCOC1=CC=C2N=C(NC(=O)OC)NC2=C1 RAOCRURYZCVHMG-UHFFFAOYSA-N 0.000 description 1
JMPFSEBWVLAJKM-UHFFFAOYSA-N N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide Chemical compound ClC=1C=C(NC(=O)C=2C(=C(I)C=C(I)C=2)O)C(C)=CC=1C(C#N)C1=CC=C(Cl)C=C1 JMPFSEBWVLAJKM-UHFFFAOYSA-N 0.000 description 1
238000005481 NMR spectroscopy Methods 0.000 description 1
239000005642 Oleic acid Substances 0.000 description 1
ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
QIPQASLPWJVQMH-DTORHVGOSA-N Orbifloxacin Chemical compound C1[C@@H](C)N[C@@H](C)CN1C1=C(F)C(F)=C2C(=O)C(C(O)=O)=CN(C3CC3)C2=C1F QIPQASLPWJVQMH-DTORHVGOSA-N 0.000 description 1
241000238887 Ornithodoros Species 0.000 description 1
239000004100 Oxytetracycline Substances 0.000 description 1
JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 description 1
239000004349 Polyvinylpyrrolidone-vinyl acetate copolymer Substances 0.000 description 1
OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Chemical class OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
208000003251 Pruritus Diseases 0.000 description 1
241001649230 Psoroptes ovis Species 0.000 description 1
241001649231 Psoroptidae Species 0.000 description 1
241001481696 Rhipicephalus sanguineus Species 0.000 description 1
241000509427 Sarcoptes scabiei Species 0.000 description 1
241000509418 Sarcoptidae Species 0.000 description 1
206010039509 Scab Diseases 0.000 description 1
239000005930 Spinosad Substances 0.000 description 1
241000187747 Streptomyces Species 0.000 description 1
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
229930006000 Sucrose Natural products 0.000 description 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Chemical class [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
239000004098 Tetracycline Substances 0.000 description 1
239000005942 Triflumuron Substances 0.000 description 1
241001584775 Tunga penetrans Species 0.000 description 1
241000353224 Xenopsylla Species 0.000 description 1
229920002494 Zein Polymers 0.000 description 1
VXSIXFKKSNGRRO-MXOVTSAMSA-N [(1s)-2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[(1s)-2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-3-[(e)-3-methoxy-2-methyl-3-oxoprop-1-enyl Chemical class CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)O[C@@H]1C(C)=C(C\C=C/C=C)C(=O)C1.CC1(C)[C@H](/C=C(\C)C(=O)OC)[C@H]1C(=O)O[C@@H]1C(C)=C(C\C=C/C=C)C(=O)C1 VXSIXFKKSNGRRO-MXOVTSAMSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
230000000895 acaricidal effect Effects 0.000 description 1
239000000642 acaricide Substances 0.000 description 1
YASYVMFAVPKPKE-UHFFFAOYSA-N acephate Chemical compound COP(=O)(SC)NC(C)=O YASYVMFAVPKPKE-UHFFFAOYSA-N 0.000 description 1
239000013543 active substance Substances 0.000 description 1
239000000853 adhesive Substances 0.000 description 1
230000001070 adhesive effect Effects 0.000 description 1
239000002671 adjuvant Substances 0.000 description 1
239000008272 agar Substances 0.000 description 1
QGLZXHRNAYXIBU-WEVVVXLNSA-N aldicarb Chemical compound CNC(=O)O\N=C\C(C)(C)SC QGLZXHRNAYXIBU-WEVVVXLNSA-N 0.000 description 1
229940024113 allethrin Drugs 0.000 description 1
229910000147 aluminium phosphate Inorganic materials 0.000 description 1
SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 1
229960002587 amitraz Drugs 0.000 description 1
QXAITBQSYVNQDR-ZIOPAAQOSA-N amitraz Chemical compound C=1C=C(C)C=C(C)C=1/N=C/N(C)\C=N\C1=CC=C(C)C=C1C QXAITBQSYVNQDR-ZIOPAAQOSA-N 0.000 description 1
229960000723 ampicillin Drugs 0.000 description 1
AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 1
230000000507 anthelmentic effect Effects 0.000 description 1
229940124339 anthelmintic agent Drugs 0.000 description 1
239000000921 anthelmintic agent Substances 0.000 description 1
230000002528 anti-freeze Effects 0.000 description 1
229940121363 anti-inflammatory agent Drugs 0.000 description 1
239000002260 anti-inflammatory agent Substances 0.000 description 1
230000003110 anti-inflammatory effect Effects 0.000 description 1
239000004599 antimicrobial Substances 0.000 description 1
229940125687 antiparasitic agent Drugs 0.000 description 1
229960003093 antiseptics and disinfectants Drugs 0.000 description 1
CJJOSEISRRTUQB-UHFFFAOYSA-N azinphos-methyl Chemical group C1=CC=C2C(=O)N(CSP(=S)(OC)OC)N=NC2=C1 CJJOSEISRRTUQB-UHFFFAOYSA-N 0.000 description 1
229940097012 bacillus thuringiensis Drugs 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
239000000440 bentonite Substances 0.000 description 1
229910000278 bentonite Inorganic materials 0.000 description 1
235000012216 bentonite Nutrition 0.000 description 1
SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
SRSXLGNVWSONIS-UHFFFAOYSA-N benzenesulfonic acid Chemical class OS(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-N 0.000 description 1
229940092714 benzenesulfonic acid Drugs 0.000 description 1
150000001556 benzimidazoles Chemical class 0.000 description 1
150000001558 benzoic acid derivatives Chemical class 0.000 description 1
239000003781 beta lactamase inhibitor Substances 0.000 description 1
229940126813 beta-lactamase inhibitor Drugs 0.000 description 1
230000037396 body weight Effects 0.000 description 1
239000000872 buffer Substances 0.000 description 1
239000002775 capsule Substances 0.000 description 1
229960005286 carbaryl Drugs 0.000 description 1
CVXBEEMKQHEXEN-UHFFFAOYSA-N carbaryl Chemical compound C1=CC=C2C(OC(=O)NC)=CC=CC2=C1 CVXBEEMKQHEXEN-UHFFFAOYSA-N 0.000 description 1
239000001768 carboxy methyl cellulose Substances 0.000 description 1
235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
239000008112 carboxymethyl-cellulose Substances 0.000 description 1
229950009592 cefquinome Drugs 0.000 description 1
229960005229 ceftiofur Drugs 0.000 description 1
ZBHXIWJRIFEVQY-IHMPYVIRSA-N ceftiofur Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC(=O)C1=CC=CO1 ZBHXIWJRIFEVQY-IHMPYVIRSA-N 0.000 description 1
235000013339 cereals Nutrition 0.000 description 1
CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 description 1
SBPBAQFWLVIOKP-UHFFFAOYSA-N chlorpyrifos Chemical compound CCOP(=S)(OCC)OC1=NC(Cl)=C(Cl)C=C1Cl SBPBAQFWLVIOKP-UHFFFAOYSA-N 0.000 description 1
229960004475 chlortetracycline Drugs 0.000 description 1
CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 description 1
235000019365 chlortetracycline Nutrition 0.000 description 1
HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 description 1
229960003324 clavulanic acid Drugs 0.000 description 1
229960000275 clorsulon Drugs 0.000 description 1
229950004178 closantel Drugs 0.000 description 1
239000003224 coccidiostatic agent Substances 0.000 description 1
230000001010 compromised effect Effects 0.000 description 1
238000011109 contamination Methods 0.000 description 1
238000013270 controlled release Methods 0.000 description 1
150000001880 copper compounds Chemical class 0.000 description 1
229910001956 copper hydroxide Inorganic materials 0.000 description 1
230000008878 coupling Effects 0.000 description 1
238000010168 coupling process Methods 0.000 description 1
238000005859 coupling reaction Methods 0.000 description 1
229960001591 cyfluthrin Drugs 0.000 description 1
QQODLKZGRKWIFG-QSFXBCCZSA-N cyfluthrin Chemical compound CC1(C)[C@@H](C=C(Cl)Cl)[C@H]1C(=O)O[C@@H](C#N)C1=CC=C(F)C(OC=2C=CC=CC=2)=C1 QQODLKZGRKWIFG-QSFXBCCZSA-N 0.000 description 1
229960005424 cypermethrin Drugs 0.000 description 1
KAATUXNTWXVJKI-UHFFFAOYSA-N cypermethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 KAATUXNTWXVJKI-UHFFFAOYSA-N 0.000 description 1
LVQDKIWDGQRHTE-UHFFFAOYSA-N cyromazine Chemical compound NC1=NC(N)=NC(NC2CC2)=N1 LVQDKIWDGQRHTE-UHFFFAOYSA-N 0.000 description 1
229950000775 cyromazine Drugs 0.000 description 1
230000034994 death Effects 0.000 description 1
FHIVAFMUCKRCQO-UHFFFAOYSA-N diazinon Chemical compound CCOP(=S)(OCC)OC1=CC(C)=NC(C(C)C)=N1 FHIVAFMUCKRCQO-UHFFFAOYSA-N 0.000 description 1
RCJVRSBWZCNNQT-UHFFFAOYSA-N dichloridooxygen Chemical compound ClOCl RCJVRSBWZCNNQT-UHFFFAOYSA-N 0.000 description 1
UOAMTSKGCBMZTC-UHFFFAOYSA-N dicofol Chemical compound C=1C=C(Cl)C=CC=1C(C(Cl)(Cl)Cl)(O)C1=CC=C(Cl)C=C1 UOAMTSKGCBMZTC-UHFFFAOYSA-N 0.000 description 1
VEENJGZXVHKXNB-VOTSOKGWSA-N dicrotophos Chemical compound COP(=O)(OC)O\C(C)=C\C(=O)N(C)C VEENJGZXVHKXNB-VOTSOKGWSA-N 0.000 description 1
JXSJBGJIGXNWCI-UHFFFAOYSA-N diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate Chemical compound CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC JXSJBGJIGXNWCI-UHFFFAOYSA-N 0.000 description 1
229950001733 difloxacin Drugs 0.000 description 1
NOCJXYPHIIZEHN-UHFFFAOYSA-N difloxacin Chemical compound C1CN(C)CCN1C(C(=C1)F)=CC2=C1C(=O)C(C(O)=O)=CN2C1=CC=C(F)C=C1 NOCJXYPHIIZEHN-UHFFFAOYSA-N 0.000 description 1
QQQYTWIFVNKMRW-UHFFFAOYSA-N diflubenzuron Chemical compound FC1=CC=CC(F)=C1C(=O)NC(=O)NC1=CC=C(Cl)C=C1 QQQYTWIFVNKMRW-UHFFFAOYSA-N 0.000 description 1
229940019503 diflubenzuron Drugs 0.000 description 1
MCWXGJITAZMZEV-UHFFFAOYSA-N dimethoate Chemical compound CNC(=O)CSP(=S)(OC)OC MCWXGJITAZMZEV-UHFFFAOYSA-N 0.000 description 1
FFHWGQQFANVOHV-UHFFFAOYSA-N dimethyldioxirane Chemical compound CC1(C)OO1 FFHWGQQFANVOHV-UHFFFAOYSA-N 0.000 description 1
230000003292 diminished effect Effects 0.000 description 1
150000004844 dioxiranes Chemical class 0.000 description 1
230000006806 disease prevention Effects 0.000 description 1
239000006185 dispersion Substances 0.000 description 1
DOFZAZXDOSGAJZ-UHFFFAOYSA-N disulfoton Chemical compound CCOP(=S)(OCC)SCCSCC DOFZAZXDOSGAJZ-UHFFFAOYSA-N 0.000 description 1
239000002552 dosage form Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000003814 drug Substances 0.000 description 1
244000078703 ectoparasite Species 0.000 description 1
235000013601 eggs Nutrition 0.000 description 1
230000008030 elimination Effects 0.000 description 1
238000003379 elimination reaction Methods 0.000 description 1
244000079386 endoparasite Species 0.000 description 1
RDYMFSUJUZBWLH-SVWSLYAFSA-N endosulfan Chemical compound C([C@@H]12)OS(=O)OC[C@@H]1[C@]1(Cl)C(Cl)=C(Cl)[C@@]2(Cl)C1(Cl)Cl RDYMFSUJUZBWLH-SVWSLYAFSA-N 0.000 description 1
NYPJDWWKZLNGGM-RPWUZVMVSA-N esfenvalerate Chemical compound C=1C([C@@H](C#N)OC(=O)[C@@H](C(C)C)C=2C=CC(Cl)=CC=2)=CC=CC=1OC1=CC=CC=C1 NYPJDWWKZLNGGM-RPWUZVMVSA-N 0.000 description 1
230000002349 favourable effect Effects 0.000 description 1
230000004634 feeding behavior Effects 0.000 description 1
HDDSHPAODJUKPD-UHFFFAOYSA-N fenbendazole Chemical compound C1=C2NC(NC(=O)OC)=NC2=CC=C1SC1=CC=CC=C1 HDDSHPAODJUKPD-UHFFFAOYSA-N 0.000 description 1
229960005473 fenbendazole Drugs 0.000 description 1
238000013100 final test Methods 0.000 description 1
229960003760 florfenicol Drugs 0.000 description 1
YOWNVPAUWYHLQX-UHFFFAOYSA-N fluazuron Chemical compound FC1=CC=CC(F)=C1C(=O)NC(=O)NC1=CC=C(Cl)C(OC=2C(=CC(=CN=2)C(F)(F)F)Cl)=C1 YOWNVPAUWYHLQX-UHFFFAOYSA-N 0.000 description 1
229950006719 fluazuron Drugs 0.000 description 1
229940124307 fluoroquinolone Drugs 0.000 description 1
238000005187 foaming Methods 0.000 description 1
230000008014 freezing Effects 0.000 description 1
238000007710 freezing Methods 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
239000008187 granular material Substances 0.000 description 1
125000001188 haloalkyl group Chemical group 0.000 description 1
229910052736 halogen Inorganic materials 0.000 description 1
125000005843 halogen group Chemical group 0.000 description 1
150000004942 imidazo[1,2-b]pyridazines Chemical class 0.000 description 1
230000001900 immune effect Effects 0.000 description 1
239000000543 intermediate Substances 0.000 description 1
238000002955 isolation Methods 0.000 description 1
QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
230000000366 juvenile effect Effects 0.000 description 1
239000003835 ketolide antibiotic agent Substances 0.000 description 1
239000008101 lactose Substances 0.000 description 1
239000005910 lambda-Cyhalothrin Substances 0.000 description 1
229960001614 levamisole Drugs 0.000 description 1
239000002502 liposome Substances 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000000314 lubricant Substances 0.000 description 1
235000019359 magnesium stearate Nutrition 0.000 description 1
229960000453 malathion Drugs 0.000 description 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical class OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
239000011976 maleic acid Chemical class 0.000 description 1
238000007726 management method Methods 0.000 description 1
239000000594 mannitol Substances 0.000 description 1
235000010355 mannitol Nutrition 0.000 description 1
229960002531 marbofloxacin Drugs 0.000 description 1
239000008204 material by function Substances 0.000 description 1
230000013011 mating Effects 0.000 description 1
230000007758 mating behavior Effects 0.000 description 1
NNKVPIKMPCQWCG-UHFFFAOYSA-N methamidophos Chemical compound COP(N)(=O)SC NNKVPIKMPCQWCG-UHFFFAOYSA-N 0.000 description 1
UHXUZOCRWCRNSJ-QPJJXVBHSA-N methomyl Chemical compound CNC(=O)O\N=C(/C)SC UHXUZOCRWCRNSJ-QPJJXVBHSA-N 0.000 description 1
229950003442 methoprene Drugs 0.000 description 1
229930002897 methoprene Natural products 0.000 description 1
GEPDYQSQVLXLEU-AATRIKPKSA-N methyl (e)-3-dimethoxyphosphoryloxybut-2-enoate Chemical compound COC(=O)\C=C(/C)OP(=O)(OC)OC GEPDYQSQVLXLEU-AATRIKPKSA-N 0.000 description 1
229920000609 methyl cellulose Polymers 0.000 description 1
239000001923 methylcellulose Substances 0.000 description 1
229960001952 metrifonate Drugs 0.000 description 1
230000000813 microbial effect Effects 0.000 description 1
244000005700 microbiome Species 0.000 description 1
150000007522 mineralic acids Chemical class 0.000 description 1
201000002266 mite infestation Diseases 0.000 description 1
DEDOPGXGGQYYMW-UHFFFAOYSA-N molinate Chemical compound CCSC(=O)N1CCCCCC1 DEDOPGXGGQYYMW-UHFFFAOYSA-N 0.000 description 1
150000002772 monosaccharides Chemical class 0.000 description 1
210000000214 mouth Anatomy 0.000 description 1
230000017074 necrotic cell death Effects 0.000 description 1
YNFMRVVYUVPIAN-AQUURSMBSA-N nemadectin Chemical compound C1[C@H](O)[C@H](C)[C@@H](C(/C)=C/C(C)C)O[C@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 YNFMRVVYUVPIAN-AQUURSMBSA-N 0.000 description 1
YNFMRVVYUVPIAN-UHFFFAOYSA-N nemadectin alpha Natural products C1C(O)C(C)C(C(C)=CC(C)C)OC11OC(CC=C(C)CC(C)C=CC=C2C3(C(C(=O)O4)C=C(C)C(O)C3OC2)O)CC4C1 YNFMRVVYUVPIAN-UHFFFAOYSA-N 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
229960002715 nicotine Drugs 0.000 description 1
SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
229910052757 nitrogen Inorganic materials 0.000 description 1
SGKGVABHDAQAJO-UHFFFAOYSA-N nitroxynil Chemical compound OC1=C(I)C=C(C#N)C=C1[N+]([O-])=O SGKGVABHDAQAJO-UHFFFAOYSA-N 0.000 description 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
229960004780 orbifloxacin Drugs 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
229960002762 oxibendazole Drugs 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
JYWIYHUXVMAGLG-UHFFFAOYSA-N oxyclozanide Chemical compound OC1=C(Cl)C=C(Cl)C=C1NC(=O)C1=C(O)C(Cl)=CC(Cl)=C1Cl JYWIYHUXVMAGLG-UHFFFAOYSA-N 0.000 description 1
229950003126 oxyclozanide Drugs 0.000 description 1
PMCVMORKVPSKHZ-UHFFFAOYSA-N oxydemeton-methyl Chemical compound CCS(=O)CCSP(=O)(OC)OC PMCVMORKVPSKHZ-UHFFFAOYSA-N 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
229960000625 oxytetracycline Drugs 0.000 description 1
IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 description 1
235000019366 oxytetracycline Nutrition 0.000 description 1
239000002297 parasiticide Substances 0.000 description 1
LCCNCVORNKJIRZ-UHFFFAOYSA-N parathion Chemical compound CCOP(=S)(OCC)OC1=CC=C([N+]([O-])=O)C=C1 LCCNCVORNKJIRZ-UHFFFAOYSA-N 0.000 description 1
RLBIQVVOMOPOHC-UHFFFAOYSA-N parathion-methyl Chemical compound COP(=S)(OC)OC1=CC=C([N+]([O-])=O)C=C1 RLBIQVVOMOPOHC-UHFFFAOYSA-N 0.000 description 1
239000006072 paste Substances 0.000 description 1
229940049954 penicillin Drugs 0.000 description 1
150000002960 penicillins Chemical class 0.000 description 1
NQPDZGIKBAWPEJ-UHFFFAOYSA-N pentanoic acid group Chemical class C(CCCC)(=O)O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 description 1
229960000490 permethrin Drugs 0.000 description 1
RLLPVAHGXHCWKJ-UHFFFAOYSA-N permethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-UHFFFAOYSA-N 0.000 description 1
150000004965 peroxy acids Chemical class 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
230000003285 pharmacodynamic effect Effects 0.000 description 1
150000002989 phenols Chemical class 0.000 description 1
125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
BULVZWIRKLYCBC-UHFFFAOYSA-N phorate Chemical compound CCOP(=S)(OCC)SCSCC BULVZWIRKLYCBC-UHFFFAOYSA-N 0.000 description 1
IOUNQDKNJZEDEP-UHFFFAOYSA-N phosalone Chemical compound C1=C(Cl)C=C2OC(=O)N(CSP(=S)(OCC)OCC)C2=C1 IOUNQDKNJZEDEP-UHFFFAOYSA-N 0.000 description 1
230000004962 physiological condition Effects 0.000 description 1
239000011118 polyvinyl acetate Substances 0.000 description 1
239000001267 polyvinylpyrrolidone Substances 0.000 description 1
229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
235000019448 polyvinylpyrrolidone-vinyl acetate copolymer Nutrition 0.000 description 1
229920001592 potato starch Polymers 0.000 description 1
230000003389 potentiating effect Effects 0.000 description 1
239000000843 powder Substances 0.000 description 1
229960002957 praziquantel Drugs 0.000 description 1
230000002265 prevention Effects 0.000 description 1
229940002612 prodrug Drugs 0.000 description 1
239000000651 prodrug Substances 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
229960005134 pyrantel Drugs 0.000 description 1
YSAUAVHXTIETRK-AATRIKPKSA-N pyrantel Chemical compound CN1CCCN=C1\C=C\C1=CC=CS1 YSAUAVHXTIETRK-AATRIKPKSA-N 0.000 description 1
HYJYGLGUBUDSLJ-UHFFFAOYSA-N pyrethrin Natural products CCC(=O)OC1CC(=C)C2CC3OC3(C)C2C2OC(=O)C(=C)C12 HYJYGLGUBUDSLJ-UHFFFAOYSA-N 0.000 description 1
229940070846 pyrethrins Drugs 0.000 description 1
239000002728 pyrethroid Substances 0.000 description 1
150000003230 pyrimidines Chemical class 0.000 description 1
239000005871 repellent Substances 0.000 description 1
230000002940 repellent Effects 0.000 description 1
229940108410 resmethrin Drugs 0.000 description 1
VEMKTZHHVJILDY-FIWHBWSRSA-N resmethrin Chemical compound CC1(C)[C@H](C=C(C)C)C1C(=O)OCC1=COC(CC=2C=CC=CC=2)=C1 VEMKTZHHVJILDY-FIWHBWSRSA-N 0.000 description 1
229940100486 rice starch Drugs 0.000 description 1
238000004062 sedimentation Methods 0.000 description 1
229960001922 sodium perborate Drugs 0.000 description 1
YKLJGMBLPUQQOI-UHFFFAOYSA-M sodium;oxidooxy(oxo)borane Chemical compound [Na+].[O-]OB=O YKLJGMBLPUQQOI-UHFFFAOYSA-M 0.000 description 1
239000002904 solvent Substances 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
229940014213 spinosad Drugs 0.000 description 1
239000000126 substance Substances 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
239000000375 suspending agent Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1
230000002459 sustained effect Effects 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
238000010189 synthetic method Methods 0.000 description 1
229920001059 synthetic polymer Polymers 0.000 description 1
230000009885 systemic effect Effects 0.000 description 1
239000003826 tablet Substances 0.000 description 1
239000011975 tartaric acid Chemical class 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
235000019364 tetracycline Nutrition 0.000 description 1
150000003522 tetracyclines Chemical class 0.000 description 1
229940040944 tetracyclines Drugs 0.000 description 1
CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
OTVAEFIXJLOWRX-NXEZZACHSA-N thiamphenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl)C=C1 OTVAEFIXJLOWRX-NXEZZACHSA-N 0.000 description 1
229960003053 thiamphenicol Drugs 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
230000009974 thixotropic effect Effects 0.000 description 1
239000011573 trace mineral Substances 0.000 description 1
235000013619 trace mineral Nutrition 0.000 description 1
YWSCPYYRJXKUDB-KAKFPZCNSA-N tralomethrin Chemical compound CC1(C)[C@@H](C(Br)C(Br)(Br)Br)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 YWSCPYYRJXKUDB-KAKFPZCNSA-N 0.000 description 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Chemical class OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
NFACJZMKEDPNKN-UHFFFAOYSA-N trichlorfon Chemical compound COP(=O)(OC)C(O)C(Cl)(Cl)Cl NFACJZMKEDPNKN-UHFFFAOYSA-N 0.000 description 1
XAIPTRIXGHTTNT-UHFFFAOYSA-N triflumuron Chemical compound C1=CC(OC(F)(F)F)=CC=C1NC(=O)NC(=O)C1=CC=CC=C1Cl XAIPTRIXGHTTNT-UHFFFAOYSA-N 0.000 description 1
229960005486 vaccine Drugs 0.000 description 1
239000003981 vehicle Substances 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
239000001993 wax Substances 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1
229940100445 wheat starch Drugs 0.000 description 1
239000000230 xanthan gum Substances 0.000 description 1
229920001285 xanthan gum Polymers 0.000 description 1
235000010493 xanthan gum Nutrition 0.000 description 1
229940082509 xanthan gum Drugs 0.000 description 1
239000005019 zein Substances 0.000 description 1
229940093612 zein Drugs 0.000 description 1
150000003952 β-lactams Chemical class 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0029—Parenteral nutrition; Parenteral nutrition compositions as drug carriers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Nutrition Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Physiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Agronomy & Crop Science (AREA)
Plant Pathology (AREA)
Dentistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Pest Control & Pesticides (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Fodder In General (AREA)
Feed For Specific Animals (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicinal Preparation (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK08771978.7T 2007-06-27 2008-06-26 PROCEDURE TO COMBAT PESTS WITH ANIMALS DK2182945T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US93738907P	2007-06-27	2007-06-27
PCT/US2008/068268 WO2009003075A1 (en)	2007-06-27	2008-06-26	Animal pest control method

Publications (1)

Publication Number	Publication Date
DK2182945T3 true DK2182945T3 (en)	2015-11-16

Family

ID=40003056

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK08771978.7T DK2182945T3 (en)	2007-06-27	2008-06-26	PROCEDURE TO COMBAT PESTS WITH ANIMALS
DK15178198.6T DK2957284T3 (en)	2007-06-27	2008-06-26	PROCEDURE TO CHECK ANIMALS FOR ANIMALS

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK15178198.6T DK2957284T3 (en)	2007-06-27	2008-06-26	PROCEDURE TO CHECK ANIMALS FOR ANIMALS

Country Status (22)

Country	Link
US (3)	US11278533B2 (2)
EP (3)	EP2182945B1 (2)
JP (6)	JP6006471B2 (2)
KR (3)	KR101769728B1 (2)
CN (2)	CN101743000A (2)
AU (1)	AU2008268321C1 (2)
BR (1)	BRPI0810929B8 (2)
CA (2)	CA2685072C (2)
CY (1)	CY1120038T1 (2)
DK (2)	DK2182945T3 (2)
ES (2)	ES2549731T3 (2)
HK (2)	HK1225622A1 (2)
HR (2)	HRP20150978T1 (2)
HU (1)	HUE037127T2 (2)
LT (1)	LT2957284T (2)
MX (3)	MX368680B (2)
NO (1)	NO2957284T3 (2)
PL (1)	PL2957284T3 (2)
PT (2)	PT2957284T (2)
RU (1)	RU2508102C2 (2)
SI (2)	SI2957284T1 (2)
WO (1)	WO2009003075A1 (2)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101768129B (zh)	2004-03-05	2012-05-23	日产化学工业株式会社	异*唑啉取代苯甲酰胺化合物的制备中间体
TW200803740A (en) *	2005-12-16	2008-01-16	Du Pont	5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh)	2005-12-30	2013-10-21	Du Pont	控制無脊椎害蟲之異唑啉
WO2008154528A2 (en)	2007-06-13	2008-12-18	E. I. Du Pont De Nemours And Company	Isoxazoline insecticides
TWI430995B (zh)	2007-06-26	2014-03-21	Du Pont	萘異唑啉無脊椎有害動物控制劑
KR101769728B1 (ko) *	2007-06-27	2017-08-18	이 아이 듀폰 디 네모아 앤드 캄파니	동물 해충 방제 방법
TWI600639B (zh)	2007-08-17	2017-10-01	杜邦股份有限公司	製備５-鹵烷基-４，５-二氫異唑衍生物之化合物
TWI556741B (zh) *	2007-08-17	2016-11-11	英特威特國際股份有限公司	異唑啉組成物及其作為抗寄生蟲藥上的應用
MX2010003557A (es)	2007-10-03	2010-04-12	Du Pont	Compuestos de isoxazolina de naftaleno para el control de plagas de invertebrados.
TWI518076B (zh)	2008-04-09	2016-01-21	杜邦股份有限公司	製備雜環化合物之方法
CN102149695B (zh)	2008-07-09	2015-02-04	日产化学工业株式会社	异*唑啉取代的苯甲酰胺化合物的制造方法
CN102088856B (zh)	2008-07-09	2015-11-25	巴斯夫欧洲公司	包含异*唑啉化合物的杀虫活性混合物i
BRPI0915818A2 (pt) *	2008-07-09	2015-08-04	Basf Se	Mistura pesticida, composição pesticida, método para controlar fungos nocivos fitopatogênicos, para proteger plantas de fungos nocivos fitopatogênicos, para controlar insetos, aracnídeos ou nematódeos, para proteger plantas do ataque ou infestação por insetos, acarídeos ou nematódeos, e para a proteção de semente, semente, e, uso de uma mistura.
EP2331536B1 (en)	2008-08-22	2013-08-21	Syngenta Participations AG	Insecticidal compounds
JP2012500782A (ja)	2008-08-22	2012-01-12	シンジェンタパーティシペーションズアクチェンゲゼルシャフト	殺虫化合物類
JP2012501989A (ja)	2008-09-04	2012-01-26	シンジェンタパーティシペーションズアクチェンゲゼルシャフト	殺虫化合物
AR074024A1 (es)	2008-11-14	2010-12-15	Merial Ltd	Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria
MY155497A (en)	2008-11-19	2015-10-30	Merial Inc	Compositions comprising an aryl pyrazole and/or a formamidine, methods and use thereof
JP5595412B2 (ja)	2008-12-04	2014-09-24	メリアルリミテッド	二量体アベルメクチン及びミルベマイシン誘導体
US8853410B2 (en)	2009-04-30	2014-10-07	Basf Se	Process for preparing substituted isoxazoline compounds and their precursors
TWI487486B (zh)	2009-12-01	2015-06-11	Syngenta Participations Ag	以異唑啉衍生物為主之殺蟲化合物
RS54772B1 (sr)	2009-12-17	2016-10-31	Merial Sas	Antiparazitska jedinjenja dihidroazola i kompozicije koje ih sadrže
WO2011095581A1 (en)	2010-02-05	2011-08-11	Intervet International B.V.	S piroindoline compounds for use as anthelminthi cs
UA108641C2 (uk)	2010-04-02	2015-05-25		Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
UA108881C2 (xx)	2010-05-27	2015-06-25		Кристалічна форма 4-$5-$3-хлор-5-(трифторметил)феніл]-4,5-дигідро-5-(трифторметил)-3-ізоксазоліл]-n-$2-оксо-2-$(2,2,2-трифторетил)аміно]етил]-1-нафталінкарбоксаміду
US9085541B2 (en)	2010-06-23	2015-07-21	Basf Se	Process for producing imine compounds for combating invertebrate pests
WO2012007426A1 (en)	2010-07-13	2012-01-19	Basf Se	Azoline substituted isoxazoline benzamide compounds for combating animal pests
KR101916481B1 (ko)	2010-09-29	2018-11-07	인터벳 인터내셔널 비.브이.	Ｎ-헤테로아릴 화합물
US8883791B2 (en)	2010-09-29	2014-11-11	Intervet Inc.	N-heteroaryl compounds with cyclic bridging unit for the treatment of parasitic diseases
EP2635552A2 (en)	2010-11-03	2013-09-11	Basf Se	Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes
JP2014028758A (ja)	2010-11-19	2014-02-13	Nissan Chem Ind Ltd	寄生虫及び衛生害虫防除剤
DE102010063691A1 (de)	2010-12-21	2012-06-21	Bayer Animal Health Gmbh	Ektoparasitizide Wirkstoffkombinationen
NZ611474A (en)	2010-12-27	2015-08-28	Intervet Int Bv	Topical localized isoxazoline formulation comprising glycofurol
JP6002148B2 (ja)	2010-12-27	2016-10-05	インターベットインターナショナルベー．フェー．	経表面局所イソオキサゾリン製剤
ES2618813T3 (es)	2011-06-27	2017-06-22	Merial, Inc.	Compuestos y composiciones de éter amido-piridílico y uso contra los parásitos
WO2013017678A1 (en)	2011-08-04	2013-02-07	Intervet International B.V.	Novel spiroindoline compounds
RS58417B1 (sr)	2011-09-12	2019-04-30	Merial Inc	Paraziticidne kompozicije koje sadrže izoksazolinsko aktivno sredstvo, postupci i upotrebe povezane sa njima
CA2851412A1 (en)	2011-10-19	2013-04-25	Zoetis Llc	Use of aminoacetonitrile derivatives against endoparasites
AU2012340351B2 (en)	2011-11-17	2017-06-15	Boehringer Ingelheim Animal Health USA Inc.	Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof
BR112014013371B1 (pt)	2011-12-02	2020-04-07	Merial Ltd	formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
CA2858766A1 (en) *	2011-12-23	2013-06-27	Basf Se	Isothiazoline compounds for combating invertebrate pests
AU2013241854B2 (en)	2012-03-28	2017-11-02	Intervet International B.V.	Heteroaryl compounds with cyclic bridging unit for use in the treatment helminth infection
ES2744597T3 (es)	2012-03-28	2020-02-25	Intervet Int Bv	Compuestos de heteroarilo con una unidad acíclica como puente
WO2013150055A1 (en)	2012-04-04	2013-10-10	Intervet International B.V.	Solid oral pharmaceutical compositions for isoxazoline compounds
BR122015032741B1 (pt)	2012-04-20	2019-11-26	Merial Ltd	composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
AU2013245478A1 (en) *	2012-11-01	2014-05-15	Sumitomo Chemical Company, Limited	Method for administering agent for controlling ectoparasite to dog
US9532946B2 (en)	2012-11-20	2017-01-03	Intervet Inc.	Manufacturing of semi-plastic pharmaceutical dosage units
NZ723198A (en)	2012-11-20	2018-11-30	Boehringer Ingelheim Animal Health Usa Inc	Anthelmintic compounds and compositions and methods of using thereof
WO2015066277A1 (en)	2013-11-01	2015-05-07	Merial Limited	Antiparisitic and pesticidal isoxazoline compounds
US9655884B2 (en)	2013-12-10	2017-05-23	Intervet Inc.	Antiparasitic use of isoxazoline compounds
EP3082806B1 (en)	2013-12-20	2021-05-12	Intervet International B.V.	Use of isoxazoline derivatives for the treatment or prevention of arthropod infestations in poultry
EP3082867B1 (en) *	2013-12-20	2024-01-17	Intervet International B.V.	Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals
EP3131398B1 (en)	2014-04-17	2019-10-23	Boehringer Ingelheim Animal Health USA Inc.	Use of malononitrile compounds for protecting animals from parasites
ES2842592T3 (es)	2014-05-19	2021-07-14	Boehringer Ingelheim Animal Health Usa Inc	Compuestos antihelmínticos
EP3157912B1 (en)	2014-06-19	2019-02-20	Merial, Inc.	Parasiticidal compositions comprising indole derivatives, methods and uses thereof
US10864193B2 (en)	2014-10-31	2020-12-15	Boehringer Ingelheim Animal Health USA Inc.	Parasiticidal compositions comprising fipronil at high concentrations
EP3236960B1 (en)	2014-12-22	2025-01-29	Intervet International B.V.	Fluralaner for use in the treatment of demodicosis
BR112017027855B1 (pt)	2015-06-23	2022-11-16	Intervet International B.V.	Composição farmacêutica, seu uso, água potável medicamentosa e método para sua preparação
UY37137A (es)	2016-02-24	2017-09-29	Merial Inc	Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en)	2016-08-25	2018-03-01	Merial, Inc.	Method for reducing unwanted effects in parasiticidal treatments
AR111260A1 (es)	2017-03-31	2019-06-19	Intervet Int Bv	Formulación farmacéutica de la sal de crotonil amino piridina
KR102694519B1 (ko)	2017-11-07	2024-08-13	인터벳 인터내셔널 비.브이.	큰 크기의 이속사졸린 입자를 제조하는 방법
PE20201150A1 (es)	2017-11-07	2020-10-26	Intervet Int Bv	Composiciones farmaceuticas inyectables de isoxazolina y usos de las mismas
US11648238B2 (en)	2017-12-12	2023-05-16	Intervet Inc.	Implantable isoxazoline pharmaceutical compositions and uses thereof
AR113997A1 (es)	2017-12-21	2020-07-08	Intervet Int Bv	Composiciones antiparasitarias para unción dorsal continua
EP3749096A1 (en)	2018-02-08	2020-12-16	Boehringer Ingelheim Animal Health USA Inc.	Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
TWI812673B (zh) *	2018-02-12	2023-08-21	美商富曼西公司	用於防治無脊椎害蟲之萘異噁唑啉化合物
WO2020002593A1 (en)	2018-06-29	2020-01-02	Intervet International B.V.	Compound for use against helminthic infection
NZ776819A (en)	2019-01-16	2023-04-28	Boehringer Ingelheim Animal Health Usa Inc	Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
AU2020231319A1 (en)	2019-03-01	2021-10-21	Boehringer Ingelheim Animal Health USA Inc.	Injectable clorsulon compositions, methods and uses thereof
EP3927341A1 (en) *	2019-04-03	2021-12-29	Virbac	Low dose fluralaner compositions for protection against parasitic invertebrate pest
JP7558197B2 (ja)	2019-05-03	2024-09-30	インターベットインターナショナルベー．フェー．	注射可能な医薬組成物及びその使用
BR112022000982A2 (pt)	2019-07-22	2022-03-08	Intervet Int Bv	Forma de dosagem veterinária mastigável macia
MX2022007309A (es)	2019-12-16	2022-07-12	Intervet Int Bv	Composicion para control de piojos en aves de corral.
WO2021122515A1 (en)	2019-12-16	2021-06-24	Intervet International B.V.	Parasite control in ruminants
EP4075981A1 (en)	2019-12-16	2022-10-26	Intervet International B.V.	Composition for lice control
EP4077286A1 (en)	2019-12-18	2022-10-26	Elanco Tiergesundheit AG	Isoxazoline derivatives as pesticides
ES2863583B2 (es) *	2020-04-08	2022-02-15	Univ Leon	Composicion veterinaria para rumiantes
US20230310386A1 (en)	2020-05-20	2023-10-05	Intervet Inc.	Injectable pharmaceutical compositions and uses thereof
AU2021278871A1 (en)	2020-05-28	2023-01-19	Boehringer Ingelheim Animal Health USA Inc.	Bi-modal release intra-ruminal capsule device and methods of use thereof
CN111909143B (zh) *	2020-07-30	2021-10-29	山东省联合农药工业有限公司	一种异噁唑啉取代的苯甲酰胺类衍生物及其制备方法与用途
WO2022140728A1 (en)	2020-12-21	2022-06-30	Boehringer Ingelheim Animam Health Usa Inc.	Parasiticidal collar comprising isoxazoline compounds
US20240383867A1 (en) *	2021-06-16	2024-11-21	ELANCO US, Inc.	Crystalline forms of isoxazoline compound
PE20250117A1 (es)	2021-06-25	2025-01-16	Intervet Int Bv	Composiciones veterinarias apetecibles
IL326231A (en)	2023-08-02	2026-03-01	Intervet Int Bv	Carboxamide-4-quinoline compounds with anthelmintic activity
UA130006C2 (uk)	2023-08-07	2025-10-08	Юрій Юрійович Синиця	Водорозчинний комплекс афоксоланера, спосіб його отримання та ветеринарні протипаразитарні препарати, що його містять
CN119409654B (zh) *	2023-08-18	2025-09-30	瑞普生物股份有限公司	一种异噁唑啉衍生物及其制备方法与应用
WO2025191150A2 (en)	2024-03-15	2025-09-18	Krka, D.D., Novo Mesto	Stable isoxazoline formulation for topical application to the skin
WO2025218493A1 (zh) *	2024-04-16	2025-10-23	南京派特美生科技有限公司	一种异噁唑啉类化合物及应用
WO2025257633A1 (en)	2024-06-12	2025-12-18	Boehringer Ingelheim Vetmedica Gmbh	Long-acting castor oil-containing injectable formulations and methods of use thereof
WO2026006414A1 (en) *	2024-06-25	2026-01-02	Elanco Us Inc.	Isoxazol-benzamide compounds as antiparasitic compounds
WO2026021344A1 (zh) *	2024-07-20	2026-01-29	山东康乔生物科技有限公司	杀虫杀螨组合物
WO2026041786A1 (en)	2024-08-23	2026-02-26	Intervet International B.V.	Injectable veterinary composition and uses thereof

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US431857A (en)		1890-07-08		Joseph d
US623912A (en)		1899-04-25		Charles j
GB331242A (en)	1929-03-26	1930-06-26	Joseph Harrison Thomson Robert	Improved means for driving kinematographs and sound recording or reproducing means in synchronism
US3950360A (en)	1972-06-08	1976-04-13	Sankyo Company Limited	Antibiotic substances
US3984564A (en)	1972-06-08	1976-10-05	Sankyo Company Limited	Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3968207A (en) *	1973-12-10	1976-07-06	American Cyanamid Company	Method of controlling fleas and ticks on cats and dogs
US3879532A (en) *	1974-01-18	1975-04-22	Shell Oil Co	Control by isoxazoles of endoparasitic nematodes
SE434277B (sv)	1976-04-19	1984-07-16	Merck & Co Inc	Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4129568A (en)	1977-05-12	1978-12-12	Monsanto Company	2-[3-Aryl-2-isoxazolin-5-yl]benzoates
US4199569A (en)	1977-10-03	1980-04-22	Merck & Co., Inc.	Selective hydrogenation products of C-076 compounds and derivatives thereof
DE3268413D1 (en)	1981-09-03	1986-02-20	Daikin Ind Ltd	Process for preparing chlorotrifluoromethylbenzene
US4820695A (en)	1982-09-13	1989-04-11	Eli Lilly And Company	C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antibiotics
US5105009A (en)	1983-06-02	1992-04-14	Zambon S.P.A.	Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoropropane derivatives
IT1173213B (it)	1984-02-03	1987-06-18	Zambon Spa	Procedimento per fluorurare alcuni derivati dall'1l-fenil-2-ammino-1,3-propandiolo e loro intermedi
US5332835A (en)	1984-02-03	1994-07-26	Zambon S.P.A.	Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process
US4973750A (en)	1984-09-19	1990-11-27	Schering Corporation	Preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
US4582918A (en)	1984-09-19	1986-04-15	Schering Corporation	Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
ES8800986A1 (es)	1985-07-27	1987-12-01	Pfizer	Un procedimiento para la produccion de un nuevo derivado de avermectina
GB8523126D0 (en)	1985-09-19	1985-10-23	Ici Plc	Aryl pyridones
US4916154A (en)	1986-09-12	1990-04-10	American Cyanamid Company	23-Imino derivatives of LL-F28249 compounds
US4876352A (en)	1988-09-14	1989-10-24	Schering Corporation	Pressurized fluorination of hydroxy alkyl groups
US5227494A (en)	1988-09-14	1993-07-13	Schering Corporation	Process for preparing oxazoline compounds
US5075320A (en)	1989-01-04	1991-12-24	Rehmert Chalmer V Jr	Method and composition for treating parasitic infestation of animals
IL98599A (en)	1990-06-28	1995-06-29	Merck & Co Inc	Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them
NZ250394A (en)	1990-10-25	1994-10-26	Schering Corp	Fluorinated and hydroxylated oxazoline compounds
DK0616494T3 (da)	1992-05-23	1999-06-21	Novartis Ag	1-[N-(halo-3-pyridylmethyl)]-N-methylamino-1-alkylamino-2-nitroethylenderivater til bekæmpelse af lopper på husdyr
US5352832A (en)	1992-12-18	1994-10-04	Schering Corporation	Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates
US5399717A (en)	1993-09-29	1995-03-21	Merck & Co., Inc.	Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1
US5849736A (en)	1993-11-24	1998-12-15	The Dupont Merck Pharmaceutical Company	Isoxazoline and isoxazole fibrinogen receptor antagonists
GB9505651D0 (en)	1995-03-21	1995-05-10	Agrevo Uk Ltd	AgrEvo UK Limited
BR9708828A (pt)	1996-04-26	1999-08-03	Nippon Soda Co	Composto e composição herbicida
AR007292A1 (es)	1996-06-06	1999-10-27	Rohm & Haas	Compuestos aromaticos benciloxi sustituidos, una composicion fungicida, un metodo para controlar hongos fitopatogenicos y un metodo para controlarinsectos.
US5958888A (en)	1996-07-02	1999-09-28	Merial, Inc.	Water miscible macrolide solutions
US6271255B1 (en)	1996-07-05	2001-08-07	Biotica Technology Limited	Erythromycins and process for their preparation
FR2750861B1 (fr) *	1996-07-11	1998-12-24	Rhone Merieux	Procedes d'elimination des parasites, et notamment des ectoparasites de vertebres, notamment de mammiferes et compositions pour la mise en oeuvre de ce procede
US5663361A (en)	1996-08-19	1997-09-02	Schering Corporation	Process for preparing intermediates to florfenicol
US5932766A (en)	1997-05-30	1999-08-03	Abbott Laboratories	Process for the preparation of substituted keto-enamines
JP2003512290A (ja)	1997-09-10	2003-04-02	メルクエンドカムパニーインコーポレーテッド	家畜抗菌剤としての８ａ−アザライド
US6339063B1 (en)	1997-09-10	2002-01-15	Merck & Co., Inc.	9a-azalides as veterinary antimicrobial agents
AP9801420A0 (en)	1998-01-02	1998-12-31	Pfizer Prod Inc	Novel macrolides.
AU739393B2 (en)	1998-03-19	2001-10-11	Merck Sharp & Dohme Corp.	Sulfurpenta fluorophenyl pyrazoles for controlling ectoparasitic infestations
US6136838A (en)	1998-03-19	2000-10-24	Merck & Co., Inc.	Sulfurpentafluorophenylpyrazoles for controlling ectoparasitic infestations
US6140350A (en)	1998-06-08	2000-10-31	Sumitomo Chemical Company, Limited	Method for controlling ectoparasites
EP1119256B1 (en)	1998-10-09	2003-06-04	Novartis AG	Oral combination of lufenuron and nitenpyram against fleas
CA2292359C (en)	1999-01-28	2004-09-28	Pfizer Products Inc.	Novel azalides and methods of making same
EG22187A (en)	1999-04-15	2002-10-31	Aventis Cropscience Sa	New composition
GB2351081A (en)	1999-06-18	2000-12-20	Lilly Forschung Gmbh	Pharmaceutically active imidazoline compounds and analogues thereof
ATE324039T1 (de)	1999-08-12	2006-05-15	Lilly Co Eli	Verwendung von spinosad oder einer zusammensetzung enthaltend spinosad
CN1939909A (zh)	1999-12-02	2007-04-04	阿温提斯作物科学股份有限公司	控制动物中的节肢动物
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
MXPA02007305A (es)	2000-01-27	2002-11-29	Pfizer Prod Inc	Composiciones antiboticas de azalida.
DE10114597A1 (de)	2001-03-23	2002-10-02	Bayer Cropscience Gmbh	Arylisoxazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
JP4104463B2 (ja)	2001-04-27	2008-06-18	ファイザー・プロダクツ・インク	４’’−置換された−９−デオキソ−９ａ−アザ−９ａ−ホモエリスロマイシン誘導体を製造するための方法
TWI283164B (en)	2001-09-21	2007-07-01	Du Pont	Anthranilamide arthropodicide treatment
CN1649829A (zh)	2002-03-08	2005-08-03	先灵-普劳有限公司	新型氟苯尼考类抗生素
WO2004018410A1 (ja)	2002-08-26	2004-03-04	Nissan Chemical Industries, Ltd.	置換ベンズアニリド化合物及び有害生物防除剤
US20040069235A1 (en)	2002-09-27	2004-04-15	Rasa Cordelia G.	Flea feeding apparatus
DE10320782A1 (de)	2003-05-09	2004-11-25	Bayer Cropscience Ag	Substituierte Oxyarene
TWI366442B (en)	2003-07-30	2012-06-21	Novartis Ag	Palatable ductile chewable veterinary composition
WO2005041950A1 (en)	2003-11-04	2005-05-12	Akzo Nobel N.V.	Ectoparasiticidal formulations of spinosyns and azole pesticides
GB0402677D0 (en)	2003-11-06	2004-03-10	Novartis Ag	Organic compounds
CA2550660C (en)	2003-12-23	2011-03-15	Schering-Plough Ltd.	Florfenicol prodrug having improved water solubility
US7361689B2 (en)	2003-12-31	2008-04-22	Schering-Plough Animal Health Corporation	Antibacterial 1-(4-mono- and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoroproponals and preparation thereof
JP4758909B2 (ja)	2003-12-31	2011-08-31	シェーリング−プラウ・リミテッド	イミダゾ［１，２−ｂ］ピリダジン誘導体を使用することによる動物における寄生生物の制御
JP2005272452A (ja)	2004-02-23	2005-10-06	Nissan Chem Ind Ltd	置換ベンズアニリド化合物及び有害生物防除剤
CN101768129B (zh) *	2004-03-05	2012-05-23	日产化学工业株式会社	异*唑啉取代苯甲酰胺化合物的制备中间体
US20050250826A1 (en)	2004-03-26	2005-11-10	Thais Sielecki-Dzurdz	Compounds, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
EP1776116B1 (en)	2004-07-28	2010-09-29	Intervet International BV	Veterinary composition comprising an arylpyrazole and a nitroenamine with enhanced antiparasitic activity
BRPI0515917A (pt)	2004-09-23	2008-08-12	Schering Plough Ltd	controle de parasitas em animais pelo uso de novos derivados de éter de oxima de trifluorometanossulfonanilida
EP1842109A1 (en)	2005-01-25	2007-10-10	GCC IP Pty Limited	Toner detection window cleaning apparatus
JP5051340B2 (ja)	2005-06-06	2012-10-17	日産化学工業株式会社	置換イソキサゾリン化合物及び有害生物防除剤
MY146795A (en)	2005-06-09	2012-09-28	Novartis Ag	Process for the synthesis of organic compounds
WO2006135648A2 (en)	2005-06-09	2006-12-21	Schering-Plough Ltd.	Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
BRPI0617076B1 (pt) *	2005-09-02	2021-07-06	Nissan Chemical Corporation	Composto benzamida substituída por isoxazolina da fórmula (1) ou sal do mesmo; composto benzamida substituido por 4-hidroxiiminametila da fórmula (2) ou sal do mesmo; pesticida; agente agroquímico; parasiticida interno ou externo para mamíferos ou aves; inseticida ou acaricida
JP2007106756A (ja)	2005-09-14	2007-04-26	Nissan Chem Ind Ltd	置換イソキサゾリン化合物及び有害生物防除剤
TWI266597B (en) *	2005-09-27	2006-11-11	Delta Electronics Inc	Electronic apparatus capable of dissipating heat uniformly
JP2009519937A (ja) *	2005-12-14	2009-05-21	イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー	無脊椎有害生物防除用イソオキサゾリン
TW200803740A (en)	2005-12-16	2008-01-16	Du Pont	5-aryl isoxazolines for controlling invertebrate pests
JP5304981B2 (ja)	2005-12-26	2013-10-02	日産化学工業株式会社	１，３−ビス（置換フェニル）−３−ヒドロキシプロパン−１−オンおよび２−プロペン−１−オン化合物およびその塩
TWI412322B (zh)	2005-12-30	2013-10-21	Du Pont	控制無脊椎害蟲之異唑啉
WO2007105814A1 (ja)	2006-03-10	2007-09-20	Nissan Chemical Industries, Ltd.	置換イソキサゾリン化合物及び有害生物防除剤
MX2008013307A (es)	2006-04-20	2008-10-27	Du Pont	Pirazolinas para controlar plagas de invertebrados.
JPWO2007125984A1 (ja)	2006-04-28	2009-09-10	日本農薬株式会社	イソキサゾリン誘導体及び有害生物防除剤並びにその使用方法
JP2008044880A (ja)	2006-08-15	2008-02-28	Bayer Cropscience Ag	殺虫性イソオキサゾリン類
WO2008108448A1 (ja)	2007-03-07	2008-09-12	Nissan Chemical Industries, Ltd.	イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
MY146638A (en)	2007-04-10	2012-09-14	Bayer Cropscience Ag	Insecticidal aryl isoxazoline derivatives
WO2008154528A2 (en)	2007-06-13	2008-12-18	E. I. Du Pont De Nemours And Company	Isoxazoline insecticides
TWI430995B (zh)	2007-06-26	2014-03-21	Du Pont	萘異唑啉無脊椎有害動物控制劑
KR101769728B1 (ko)	2007-06-27	2017-08-18	이 아이 듀폰 디 네모아 앤드 캄파니	동물 해충 방제 방법
JP5349303B2 (ja)	2007-06-27	2013-11-20	日産化学工業株式会社	３−ヒドロキシプロパン−１−オン化合物、２−プロペン−１−オン化合物およびイソキサゾリン化合物の製造方法
TWI600639B (zh)	2007-08-17	2017-10-01	杜邦股份有限公司	製備５-鹵烷基-４，５-二氫異唑衍生物之化合物
TWI556741B (zh)	2007-08-17	2016-11-11	英特威特國際股份有限公司	異唑啉組成物及其作為抗寄生蟲藥上的應用
MX2010003557A (es)	2007-10-03	2010-04-12	Du Pont	Compuestos de isoxazolina de naftaleno para el control de plagas de invertebrados.
TWI518076B (zh)	2008-04-09	2016-01-21	杜邦股份有限公司	製備雜環化合物之方法

2008
- 2008-06-26 KR KR1020167030535A patent/KR101769728B1/ko active Active
- 2008-06-26 DK DK08771978.7T patent/DK2182945T3/en active
- 2008-06-26 CN CN200880019716A patent/CN101743000A/zh active Pending
- 2008-06-26 WO PCT/US2008/068268 patent/WO2009003075A1/en not_active Ceased
- 2008-06-26 SI SI200831932T patent/SI2957284T1/en unknown
- 2008-06-26 CA CA2685072A patent/CA2685072C/en active Active
- 2008-06-26 AU AU2008268321A patent/AU2008268321C1/en active Active
- 2008-06-26 LT LTEP15178198.6T patent/LT2957284T/lt unknown
- 2008-06-26 SI SI200831504T patent/SI2182945T1/sl unknown
- 2008-06-26 PT PT151781986T patent/PT2957284T/pt unknown
- 2008-06-26 KR KR1020157020688A patent/KR101714291B1/ko active Active
- 2008-06-26 ES ES08771978.7T patent/ES2549731T3/es active Active
- 2008-06-26 PL PL15178198T patent/PL2957284T3/pl unknown
- 2008-06-26 CN CN201610078394.1A patent/CN105640952A/zh active Pending
- 2008-06-26 KR KR1020107001744A patent/KR101714059B1/ko active Active
- 2008-06-26 MX MX2014010553A patent/MX368680B/es unknown
- 2008-06-26 EP EP08771978.7A patent/EP2182945B1/en not_active Revoked
- 2008-06-26 MX MX2009013748A patent/MX2009013748A/es active IP Right Grant
- 2008-06-26 HU HUE15178198A patent/HUE037127T2/hu unknown
- 2008-06-26 DK DK15178198.6T patent/DK2957284T3/en active
- 2008-06-26 CA CA2971008A patent/CA2971008A1/en not_active Abandoned
- 2008-06-26 EP EP15178198.6A patent/EP2957284B1/en not_active Revoked
- 2008-06-26 ES ES15178198.6T patent/ES2666187T3/es active Active
- 2008-06-26 HR HRP20150978TT patent/HRP20150978T1/hr unknown
- 2008-06-26 JP JP2010515096A patent/JP6006471B2/ja active Active
- 2008-06-26 EP EP17206287.9A patent/EP3351243A1/en active Pending
- 2008-06-26 US US12/663,848 patent/US11278533B2/en active Active
- 2008-06-26 PT PT87719787T patent/PT2182945E/pt unknown
- 2008-06-26 NO NO15178198A patent/NO2957284T3/no unknown
- 2008-06-26 RU RU2010102529/15A patent/RU2508102C2/ru not_active IP Right Cessation
- 2008-06-26 MX MX2015011173A patent/MX361762B/es unknown
- 2008-06-26 BR BRPI0810929A patent/BRPI0810929B8/pt active IP Right Grant
2014
- 2014-10-20 JP JP2014213472A patent/JP6099610B2/ja active Active
2016
- 2016-06-22 JP JP2016123353A patent/JP6258410B2/ja active Active
- 2016-07-12 US US15/207,999 patent/US20160317520A1/en not_active Abandoned
- 2016-11-11 JP JP2016220118A patent/JP6167217B2/ja active Active
- 2016-12-06 HK HK16113909.5A patent/HK1225622A1/zh unknown
2017
- 2017-12-05 JP JP2017233023A patent/JP6411621B2/ja active Active
2018
- 2018-03-16 HR HRP20180453TT patent/HRP20180453T1/hr unknown
- 2018-03-19 CY CY20181100313T patent/CY1120038T1/el unknown
- 2018-08-07 HK HK18110143.5A patent/HK1250648A1/en unknown
- 2018-08-14 US US16/103,836 patent/US20180353494A1/en not_active Abandoned
- 2018-09-25 JP JP2018178283A patent/JP2019014728A/ja active Pending

Also Published As

Publication number	Publication date
PL2957284T3 (pl)	2018-08-31
HK1250648A1 (en)	2019-01-11
RU2508102C2 (ru)	2014-02-27
AU2008268321C1 (en)	2018-09-27
EP2182945B1 (en)	2015-08-05
US11278533B2 (en)	2022-03-22
SI2957284T1 (en)	2018-04-30
CA2685072A1 (en)	2008-12-31
US20180353494A1 (en)	2018-12-13
US20150272938A2 (en)	2015-10-01
JP2016216473A (ja)	2016-12-22
JP6258410B2 (ja)	2018-01-10
JP2019014728A (ja)	2019-01-31
JP6167217B2 (ja)	2017-07-19
AU2008268321A1 (en)	2008-12-31
JP6411621B2 (ja)	2018-10-24
DK2957284T3 (en)	2018-02-05
CA2685072C (en)	2017-08-01
KR101714059B1 (ko)	2017-03-08
JP2017075152A (ja)	2017-04-20
HK1218869A1 (en)	2017-03-17
RU2010102529A (ru)	2011-08-10
ES2666187T3 (es)	2018-05-03
KR20150091544A (ko)	2015-08-11
MX368680B (es)	2019-10-11
ES2549731T3 (es)	2015-11-02
LT2957284T (lt)	2018-04-10
CN101743000A (zh)	2010-06-16
HK1225622A1 (zh)	2017-09-15
EP2957284B1 (en)	2018-01-17
US20160317520A1 (en)	2016-11-03
KR101714291B1 (ko)	2017-03-08
JP2010531893A (ja)	2010-09-30
WO2009003075A1 (en)	2008-12-31
MX2009013748A (es)	2010-01-26
EP2957284A1 (en)	2015-12-23
BRPI0810929A2 (pt)	2014-12-23
AU2008268321B2 (en)	2014-08-07
MX361762B (es)	2018-12-17
EP3351243A1 (en)	2018-07-25
BRPI0810929B1 (pt)	2019-04-09
PT2957284T (pt)	2018-04-23
CY1120038T1 (el)	2018-12-12
SI2182945T1 (sl)	2015-12-31
JP6099610B2 (ja)	2017-03-22
JP2015057399A (ja)	2015-03-26
KR101769728B1 (ko)	2017-08-18
HUE037127T2 (hu)	2018-08-28
CN105640952A (zh)	2016-06-08
HRP20150978T1 (hr)	2015-11-06
HRP20180453T1 (hr)	2018-04-20
EP2182945A1 (en)	2010-05-12
BRPI0810929B8 (pt)	2022-12-06
JP2018065849A (ja)	2018-04-26
JP6006471B2 (ja)	2016-10-12
NO2957284T3 (2)	2018-06-16
KR20160130328A (ko)	2016-11-10
US20100173948A1 (en)	2010-07-08
CA2971008A1 (en)	2008-12-31
PT2182945E (pt)	2015-11-18
KR20100045444A (ko)	2010-05-03

Publication	Publication Date	Title
DK2182945T3 (en)	2015-11-16	PROCEDURE TO COMBAT PESTS WITH ANIMALS
AU2014259503C1 (en)	2019-06-13	Animal pest control method
HK1218869B (en)	2018-06-29	Animal pest control method
HK1144786A (en)	2011-03-11	Animal pest control method