DK2189446T3 - Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller - Google Patents

Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller

Info

Publication number
DK2189446T3
DK2189446T3 DK08790795.2T DK08790795T DK2189446T3 DK 2189446 T3 DK2189446 T3 DK 2189446T3 DK 08790795 T DK08790795 T DK 08790795T DK 2189446 T3 DK2189446 T3 DK 2189446T3
Authority
DK
Denmark
Prior art keywords
benzadimine
butoxycarbonylimino
butoxycarbonyl
piperidinyl
propoxy
Prior art date
Application number
DK08790795.2T
Other languages
English (en)
Inventor
Junichi Mitsuyama
Naokatu Aoki
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Application granted granted Critical
Publication of DK2189446T3 publication Critical patent/DK2189446T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK08790795.2T 2007-07-04 2008-07-02 Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller DK2189446T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007176106 2007-07-04
PCT/JP2008/061944 WO2009005077A1 (ja) 2007-07-04 2008-07-02 ４－｛３－［４－（３－｛４－［アミノ（ブトキシカルボニルイミノ）メチル］フェノキシ｝プロピル）－１－ピペリジニル］プロポキシ｝－ｎ’－（ブトキシカルボニル）ベンズアミジンの新規な結晶

Publications (1)

Publication Number Publication Date
DK2189446T3 true DK2189446T3 (da) 2012-09-24

Family

ID=40226120

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08790795.2T DK2189446T3 (da) 2007-07-04 2008-07-02 Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller

Country Status (22)

Country Link
US (1) US8158800B2 (da)
EP (1) EP2189446B1 (da)
JP (1) JP5261386B2 (da)
KR (1) KR20100027176A (da)
CN (1) CN101730682B (da)
AU (1) AU2008272124B2 (da)
BR (1) BRPI0813104A2 (da)
CA (1) CA2691954C (da)
CY (1) CY1113210T1 (da)
DK (1) DK2189446T3 (da)
ES (1) ES2391319T3 (da)
HR (1) HRP20120796T1 (da)
IL (1) IL202804A (da)
MX (1) MX2009013913A (da)
NZ (1) NZ582187A (da)
PL (1) PL2189446T3 (da)
PT (1) PT2189446E (da)
RU (1) RU2456272C2 (da)
SI (1) SI2189446T1 (da)
TW (1) TWI395735B (da)
WO (1) WO2009005077A1 (da)
ZA (1) ZA201000027B (da)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04008526A (es) * 2002-03-06 2005-07-13 Toyama Chemical Co Ltd Novedoso derivado de arilamidina o sal del mismo.
JP4885722B2 (ja) 2004-06-30 2012-02-29 富山化学工業株式会社 新規なアリールアミジン誘導体およびその塩ならびにそれらを含有する抗真菌剤
CN101351204B (zh) * 2005-12-29 2011-01-12 富山化学工业株式会社 芳脒衍生物及其盐、以及含有它们的抗真菌药
SI2070536T1 (sl) * 2006-10-06 2012-03-30 Toyama Chemical Co Ltd Farmacevtska sestava vsebujoča derivat fenilamidina in postopek z uporabo farmacevtske sestave vkombinaciji s protiglivičnim sredstvom

Also Published As

Publication number Publication date
IL202804A0 (en) 2010-06-30
AU2008272124A1 (en) 2009-01-08
AU2008272124B2 (en) 2012-08-23
CA2691954C (en) 2014-10-28
RU2010103672A (ru) 2011-08-10
EP2189446A4 (en) 2010-10-20
CA2691954A1 (en) 2009-01-08
NZ582187A (en) 2011-03-31
JP5261386B2 (ja) 2013-08-14
MX2009013913A (es) 2010-03-10
JPWO2009005077A1 (ja) 2010-08-26
PL2189446T3 (pl) 2013-01-31
EP2189446B1 (en) 2012-08-22
EP2189446A1 (en) 2010-05-26
SI2189446T1 (sl) 2012-12-31
US20110046381A1 (en) 2011-02-24
TWI395735B (zh) 2013-05-11
HRP20120796T1 (hr) 2012-10-31
RU2456272C2 (ru) 2012-07-20
IL202804A (en) 2013-10-31
CN101730682B (zh) 2012-08-08
CN101730682A (zh) 2010-06-09
BRPI0813104A2 (pt) 2014-12-23
TW200914421A (en) 2009-04-01
ES2391319T3 (es) 2012-11-23
ZA201000027B (en) 2011-03-30
KR20100027176A (ko) 2010-03-10
PT2189446E (pt) 2012-10-25
CY1113210T1 (el) 2016-04-13
WO2009005077A1 (ja) 2009-01-08
US8158800B2 (en) 2012-04-17

Similar Documents

Publication Publication Date Title
IL269092A (en) Process for preparing 2-(9h-carbazol-4-yloxy)-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-n-({4-[(1-methylpiperidin-4-yl)amino]-3-nitrophenyl}sulfonyl)benzamide
BR112013033511A8 (pt) 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)ethóxi)fenil)butil)carbamimidoil) pirazina-2-carboxamida
CL2007002930A1 (es) Un compuesto 4-[4-({[4-cloro-3-(trifluorometil)fenil]carbamoil}amino)-3-fluorofenoxi]-n-metilpiridin-2-carboxamida monohidratado; proceso de preparacion; composicion y combinacion farmaceutica; y uso para el tratamiento de trastornos hiperproliferati
IL206470A (en) 2-Amino-1 - ((Phosphonooxy) Methyl) -3 - (3 - ((4 - ((2-Pyridinyloxy) Methyl) Phenyl) Methyl) -5-Isoxazolyl) - Pyridinium and Pharmaceutical Preparation Containing It
ITPN20080037A1 (it) "mezzi filtranti perfezionati e macchina per spazzatura pavimenti dotata di tali mezzi"
CY2017038I2 (el) Νεες φαρμακευτικες συνθεσεις που περιεχουν 4-(4-(3-(4-χλωρο-3-τριφθορομεθυλ-φαινυλ)-ουρειδο)-3-φθορο-φαινοξυ)-πυριδιν-2-καρβοξυλικο οξυ για thν θεραπευτικη αγωγη υπερπολλαπλασιαστικων διαταραχων
CY1108428T1 (el) Μονοϋδροχλωρικο αλας 1-[3 [3-(4-χλωροφαινυλ) προποξυ] προπυλ] - πιπεριδινης
ZA200804030B (en) Improved process for the preparation of 4-(benzimidazolylmethylamino)benzamides and the salts thereof
PL1937065T3 (pl) Nowe sole lizynowe pochodnych kwasu 4-((fenoksyalkilo)tio)fenoksyoctowewgo
RU2011147374A (ru) Диамидные соединения, обладающие активностью антагониста мускаринового рецептора и активностью агониста в2 адренергического рецептора
EP2262775C0 (en) SALTS D (E)-N-(2-AMINO-PHENYL)-3-{1-[4-(1-METHYL-1H-PYRAZOL-4-YL)-BENZENESULFONYL]-1H-PYRROL-3-YL}- ACRYLAMIDE
ATE516272T1 (de) 1,3-disubstituierte 4-(aryl-x-phenyl)-1h-pyridin- 2-one
ATE506359T1 (de) Heteroaryl-substituierte piperidine
JP2011518774A5 (da)
SMT201400161B (it) Nuove forme poliformiche di sale di idrocloruro di3-(1-[[3-[5-1-metil-piperidin-4il metossi)-pirimidin-2-il]-benzil]]-6-osso-1,6-didro-piridazin-3-il-benzonitrile e procedimenti per la sua produzione
PE20142355A1 (es) 1-pirazolil-3-(4-((2-anilinopirimidin-4-il)oxi)naftalen-1-il)ureas como inhibidores de proteinas cinasas activadas por mitogeno p38
CL2013000870A1 (es) Solvato de isopropanol e hidrato de la sal oxalato cristalina del 1-(2-([4-(4-([(r)-2-hidroxi-2-(8-hidroxi-2-oxo-1,2-dihidroquinolin-5-il)etilamino]metil)fenilcarbamoil)butil]metilcarbamoil)etilpiperidin-4-il ester del acido bifenil-2-ilcarbamico; composicion farmaceutica; y uso para tratar una enfermedad pulmonar, epoc y asma.
DK2155717T3 (da) 2-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-3-phenyl-pyraziner og -pyridiner og 3-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-2-phenyl-pyridiner som 5-ht7-receptorantagonister
DK2358675T3 (da) 4-[2-(2-Fluorphenoxymethyl)phenyl]piperidinforbindelser
IL259694B (en) Production method for 1-(4-(4-(4,3-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl-oxy)piperidine-1-yl)-prop-2-en-1-one hydrochloride and intermediates used for this
IL191967A0 (en) 3-(4-{[4-(4-{[3-(3,3-dimethyl-1-piperidinyl) propyl]oxy}phenyl)-1-piperidinyl]carbonyl]-1-naphthalenyl)propanoic or propenoic acid as h1 and h3 receptor antagonists for the treatment of inflammatory and/or allergic disorders
DK2131845T3 (da) 5-(2,4-Dihydroxy-5-isopropyl-phenyl)-4-(4-morpholin-4-ylmethyl-phenyl)-isoxazol-3-carboxylsyre-ethylamid-mesylat, hydrater og polymorfe deraf samt præparater, der omfatter disse former
DK2189446T3 (da) Nye 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy]-N´-(butoxycarbonyl)benzadimin-krystaller
IL200959A0 (en) Liquid formulations of salts of 4-[2-(4-methylphenylfanyl)phenyl]piperidine
PL382346A1 (pl) Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego