PL382346A1 - Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego - Google Patents

Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego

Info

Publication number
PL382346A1
PL382346A1 PL382346A PL38234607A PL382346A1 PL 382346 A1 PL382346 A1 PL 382346A1 PL 382346 A PL382346 A PL 382346A PL 38234607 A PL38234607 A PL 38234607A PL 382346 A1 PL382346 A1 PL 382346A1
Authority
PL
Poland
Prior art keywords
phenylo
sulphanylo
methyloethylo
ethenylo
cyclopropaiacetic
Prior art date
Application number
PL382346A
Other languages
English (en)
Other versions
PL205444B1 (pl
Inventor
Daniel Żyła
Robert Rynkiewicz
Mariusz Krzyżanowski
Jan Ramza
Original Assignee
Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna filed Critical Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna
Priority to PL382346A priority Critical patent/PL205444B1/pl
Priority to US12/597,746 priority patent/US20100069641A1/en
Priority to PCT/PL2008/000033 priority patent/WO2008136693A2/en
Priority to JP2010506109A priority patent/JP2010526060A/ja
Priority to RU2009143315/04A priority patent/RU2436773C2/ru
Priority to CN200880017789A priority patent/CN101679268A/zh
Priority to EP08741772A priority patent/EP2142508A2/en
Publication of PL382346A1 publication Critical patent/PL382346A1/pl
Priority to IL201779A priority patent/IL201779A0/en
Publication of PL205444B1 publication Critical patent/PL205444B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL382346A 2007-05-02 2007-05-02 Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego PL205444B1 (pl)

Priority Applications (8)

Application Number Priority Date Filing Date Title
PL382346A PL205444B1 (pl) 2007-05-02 2007-05-02 Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego
US12/597,746 US20100069641A1 (en) 2007-05-02 2008-04-30 Process for the preparation of sodium salt of 1-(((1(r)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid
PCT/PL2008/000033 WO2008136693A2 (en) 2007-05-02 2008-04-30 Process for the preparation of sodium salt of l-(((l(r)-(3-(2-(7-chloro-2- quinolinyl)-ethenyl)phenyl)-3-(2-(l-hydroxy-l- methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid
JP2010506109A JP2010526060A (ja) 2007-05-02 2008-04-30 １−（（（１（ｒ）−（３−（２−（７−クロロ−２−キノリニル）−エテニル）フェニル）−３−（２−（１−ヒドロキシ−１−メチルエチル）フェニル）プロピル）スルファニル）メチル）シクロプロパン酢酸のナトリウム塩の調製法
RU2009143315/04A RU2436773C2 (ru) 2007-05-02 2008-04-30 Способ получения натриевой соли 1-[[[(r)-m-[(е)-2-(7-хлор-2-хинолил)винил]-альфа-[о-(1-гидрокси-1-метилэтил)фенетил]бензил]тио]метил]циклопропануксусной кислоты
CN200880017789A CN101679268A (zh) 2007-05-02 2008-04-30 制备1-(((1(r)-(3-(2-(7-氯-2-喹啉基)-乙烯基)苯基)-3-(2-(1-羟基-1-甲基乙基)苯基)丙基)硫烷基)甲基)环丙乙酸的钠盐的方法
EP08741772A EP2142508A2 (en) 2007-05-02 2008-04-30 Process for the preparation of sodium salt of l-(((l(r)-(3-(2-(7-chloro-2- quinolinyl)-ethenyl)phenyl)-3-(2-(l-hydroxy-l- methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid
IL201779A IL201779A0 (en) 2007-05-02 2009-10-27 Process for the preparation of sodium salt of 1-(((1(r)-(3-(2-(7-chloro-2- quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1- methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL382346A PL205444B1 (pl) 2007-05-02 2007-05-02 Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego

Publications (2)

Publication Number Publication Date
PL382346A1 true PL382346A1 (pl) 2008-11-10
PL205444B1 PL205444B1 (pl) 2010-04-30

Family

ID=39673000

Family Applications (1)

Application Number Title Priority Date Filing Date
PL382346A PL205444B1 (pl) 2007-05-02 2007-05-02 Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego

Country Status (8)

Country Link
US (1) US20100069641A1 (pl)
EP (1) EP2142508A2 (pl)
JP (1) JP2010526060A (pl)
CN (1) CN101679268A (pl)
IL (1) IL201779A0 (pl)
PL (1) PL205444B1 (pl)
RU (1) RU2436773C2 (pl)
WO (1) WO2008136693A2 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1904448B1 (en) 2005-07-05 2011-02-02 Teva Pharmaceutical Industries, Ltd. Purification of montelukast
EP2552892A1 (en) 2010-03-31 2013-02-06 KRKA, D.D., Novo Mesto Efficient synthesis for the preparation of montelukast and novel crystalline form of intermediates therein
KR20130041664A (ko) * 2011-10-17 2013-04-25 주식회사 엘지생명과학 고순도 몬테루카스트 나트륨 염의 제조 방법
CN103570618A (zh) * 2013-09-30 2014-02-12 浙江车头制药股份有限公司 一种孟鲁司特钠盐的制备方法
CN103772275B (zh) * 2013-12-30 2015-10-28 浙江车头制药股份有限公司 孟鲁司特二正丙胺盐晶型及制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE912115A1 (en) * 1990-06-25 1992-01-01 Takeda Chemical Industries Ltd Bisphosphonic acid derivatives, their production and use
DK0480717T3 (da) 1990-10-12 1999-02-08 Merck Frosst Canada Inc Umættede hydroxyalkylquinolinsyrer som leukotrienantagonister
US5270324A (en) * 1992-04-10 1993-12-14 Merck Frosst Canada, Inc. Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists
TW448160B (en) 1993-12-28 2001-08-01 Merck & Co Inc Novel dicyclohexylamine salt and process for the preparation of leukotriene antagonists
US5952347A (en) * 1997-03-13 1999-09-14 Merck & Co., Inc. Quinoline leukotriene antagonists
US20050107612A1 (en) * 2002-12-30 2005-05-19 Dr. Reddy's Laboratories Limited Process for preparation of montelukast and its salts
KR20060117356A (ko) 2004-01-30 2006-11-16 테바 파마슈티컬 인더스트리즈 리미티드 몬테루카스트 유리산 다형체
WO2005075427A2 (en) 2004-01-30 2005-08-18 Teva Pharmaceutical Industries Ltd. Montelukast sodium polymorphs
US7189853B2 (en) * 2004-04-15 2007-03-13 Dr. Reddy's Laboratories Limited Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (Montelukast) and its pharmaceutically acceptable salts
PL205637B1 (pl) 2004-10-22 2010-05-31 Inst Farmaceutyczny Sposób wytwarzania kwasu (R,E)-(1-{1-{3-[2-(7-chlorochinolin-2-ylo)etenylo]fenylo}-3-[2-(1-hydroksy-1-metyloetylo)fenylo] propylosulfanylometylo}cyklopropylo)octowego i/lub jego farmaceutycznie dopuszczalnych soli
EP1904448B1 (en) * 2005-07-05 2011-02-02 Teva Pharmaceutical Industries, Ltd. Purification of montelukast

Also Published As

Publication number Publication date
WO2008136693A2 (en) 2008-11-13
PL205444B1 (pl) 2010-04-30
CN101679268A (zh) 2010-03-24
RU2009143315A (ru) 2011-06-10
IL201779A0 (en) 2010-06-16
RU2436773C2 (ru) 2011-12-20
WO2008136693A3 (en) 2008-12-31
EP2142508A2 (en) 2010-01-13
JP2010526060A (ja) 2010-07-29
US20100069641A1 (en) 2010-03-18

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Legal Events

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LAPS Decisions on the lapse of the protection rights

Effective date: 20130502