DK2193131T3 - Imidazo[1,2-a]pyrazinforbindelser til behandling af virusinfektioner såsom hepatitis - Google Patents

Imidazo[1,2-a]pyrazinforbindelser til behandling af virusinfektioner såsom hepatitis

Info

Publication number
DK2193131T3
DK2193131T3 DK08787346.9T DK08787346T DK2193131T3 DK 2193131 T3 DK2193131 T3 DK 2193131T3 DK 08787346 T DK08787346 T DK 08787346T DK 2193131 T3 DK2193131 T3 DK 2193131T3
Authority
DK
Denmark
Prior art keywords
imidazo
hepatitis
virus infections
pyrazine compounds
treating virus
Prior art date
Application number
DK08787346.9T
Other languages
English (en)
Inventor
Angus Macleod
Dale Robert Mitchell
Nicholas John Palmer
Christophe Claude Parsy
Michael Daniel Goldsmith
Clifford John Harris
Original Assignee
Biofocus Dpi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofocus Dpi Ltd filed Critical Biofocus Dpi Ltd
Application granted granted Critical
Publication of DK2193131T3 publication Critical patent/DK2193131T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK08787346.9T 2007-08-21 2008-08-20 Imidazo[1,2-a]pyrazinforbindelser til behandling af virusinfektioner såsom hepatitis DK2193131T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0716292.8A GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds
PCT/EP2008/060896 WO2009024585A2 (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis

Publications (1)

Publication Number Publication Date
DK2193131T3 true DK2193131T3 (da) 2013-04-22

Family

ID=38566736

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08787346.9T DK2193131T3 (da) 2007-08-21 2008-08-20 Imidazo[1,2-a]pyrazinforbindelser til behandling af virusinfektioner såsom hepatitis

Country Status (20)

Country Link
US (1) US8362018B2 (da)
EP (2) EP2567960A3 (da)
JP (1) JP2010536825A (da)
KR (1) KR20100081294A (da)
CN (1) CN101835780B (da)
AU (1) AU2008290531A1 (da)
BR (1) BRPI0815717A2 (da)
CA (1) CA2707521A1 (da)
CY (1) CY1113872T1 (da)
DK (1) DK2193131T3 (da)
ES (1) ES2404415T3 (da)
GB (1) GB0716292D0 (da)
HR (1) HRP20130202T1 (da)
MX (1) MX2010001733A (da)
NZ (1) NZ584108A (da)
PL (1) PL2193131T3 (da)
PT (1) PT2193131E (da)
SI (1) SI2193131T1 (da)
WO (1) WO2009024585A2 (da)
ZA (1) ZA201002009B (da)

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JPWO2013061962A1 (ja) * 2011-10-24 2015-04-02 武田薬品工業株式会社 二環性化合物
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BR122023023802A2 (pt) 2015-04-29 2023-12-26 Janssen Pharmaceutica Nv Compostos azabenzimidazóis, seu uso como moduladores do receptor de ampa e composições farmacêuticas que os compreendem
CN107949563B (zh) * 2015-06-24 2020-06-05 库洛维公司 治疗中有用的吡唑并[1,5-a]三嗪-4-胺衍生物
JP6507976B2 (ja) * 2015-09-30 2019-05-08 東レ株式会社 イミダゾール−２−カルボン酸エステル誘導体又はその塩の製造方法
RS63359B1 (sr) 2015-11-06 2022-07-29 Incyte Corp Heterociklična jedinjenja kao inhibitori pi3k-gama
ES2995198T3 (en) 2016-01-05 2025-02-07 Incyte Corp Pyridine compounds as pi3k-gamma inhibitors
HK1250945A1 (zh) * 2016-03-31 2019-01-18 罗马克实验室有限公司 用於治疗病毒性感染的噻唑化物化合物
TW201803871A (zh) 2016-06-24 2018-02-01 英塞特公司 作為ＰＩ３Ｋ-γ抑制劑之雜環化合物
UY37381A (es) 2016-08-30 2018-03-23 Glaxosmithkline Ip No 2 Ltd Compuestos que inhiben proteasas 3c y 3cl y métodos de uso de los mismos
KR102717072B1 (ko) 2017-10-18 2024-10-15 인사이트 코포레이션 Pi3k-감마 저해제로서의 3차 하이드록시기로 치환된 축합된 이미다졸 유도체
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TWI811428B (zh) 2018-08-21 2023-08-11 日商杏林製藥股份有限公司 雙環雜芳香環衍生物
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CN109369545B (zh) * 2018-12-14 2020-04-10 东营曜康医药科技有限公司 2-甲基-5-甲酸吡嗪的合成工艺
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CN113929633A (zh) * 2021-10-27 2022-01-14 山东大学 一种法匹拉韦的合成方法及其应用
CN113831255B (zh) * 2021-11-25 2022-03-11 山东诚创蓝海医药科技有限公司 一种2-氨基丙二酰胺的制备方法
CN115489188B (zh) * 2022-10-09 2023-08-29 安徽国风新材料股份有限公司 一种家居保护用聚酯薄膜及其制备方法
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Also Published As

Publication number Publication date
WO2009024585A2 (en) 2009-02-26
NZ584108A (en) 2012-06-29
EP2193131B1 (en) 2013-01-30
BRPI0815717A2 (pt) 2015-02-10
MX2010001733A (es) 2010-07-06
ES2404415T3 (es) 2013-05-27
EP2567960A3 (en) 2013-06-05
ZA201002009B (en) 2010-12-29
US8362018B2 (en) 2013-01-29
GB0716292D0 (en) 2007-09-26
HRP20130202T1 (hr) 2013-04-30
EP2193131A2 (en) 2010-06-09
HK1143810A1 (en) 2011-01-14
WO2009024585A3 (en) 2009-08-06
KR20100081294A (ko) 2010-07-14
PT2193131E (pt) 2013-04-04
US20110166147A1 (en) 2011-07-07
PL2193131T3 (pl) 2013-07-31
AU2008290531A1 (en) 2009-02-26
CN101835780A (zh) 2010-09-15
CA2707521A1 (en) 2009-02-26
SI2193131T1 (sl) 2013-06-28
EP2567960A2 (en) 2013-03-13
JP2010536825A (ja) 2010-12-02
CY1113872T1 (el) 2016-07-27
CN101835780B (zh) 2013-09-18

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