DK2203464T3 - Massespektrometrisk fremgangsmåde til identificering af en analyt fra en biologisk prøve, som er påvirket af en stressfaktor - Google Patents

Massespektrometrisk fremgangsmåde til identificering af en analyt fra en biologisk prøve, som er påvirket af en stressfaktor

Info

Publication number
DK2203464T3
DK2203464T3 DK08797301.2T DK08797301T DK2203464T3 DK 2203464 T3 DK2203464 T3 DK 2203464T3 DK 08797301 T DK08797301 T DK 08797301T DK 2203464 T3 DK2203464 T3 DK 2203464T3
Authority
DK
Denmark
Prior art keywords
analyte
identifying
biological sample
mass spectrometric
stress factor
Prior art date
Application number
DK08797301.2T
Other languages
English (en)
Inventor
Christopher William Ward Beecher
Original Assignee
Iroa Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iroa Technologies Llc filed Critical Iroa Technologies Llc
Application granted granted Critical
Publication of DK2203464T3 publication Critical patent/DK2203464T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5038—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving detection of metabolites per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/109163—Inorganic standards or controls
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DK08797301.2T 2007-08-06 2008-08-06 Massespektrometrisk fremgangsmåde til identificering af en analyt fra en biologisk prøve, som er påvirket af en stressfaktor DK2203464T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95425307P 2007-08-06 2007-08-06
US97692307P 2007-10-02 2007-10-02
US12/186,381 US7820963B2 (en) 2007-08-06 2008-08-05 Method for generation and use of isotopic patterns in mass spectral data of simple organisms
PCT/US2008/072358 WO2009021056A1 (en) 2007-08-06 2008-08-06 Method for generation and use of isotopic patterns in mass spectral data of simple organisms

Publications (1)

Publication Number Publication Date
DK2203464T3 true DK2203464T3 (da) 2014-02-03

Family

ID=40341714

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08797301.2T DK2203464T3 (da) 2007-08-06 2008-08-06 Massespektrometrisk fremgangsmåde til identificering af en analyt fra en biologisk prøve, som er påvirket af en stressfaktor

Country Status (7)

Country Link
US (2) US7820963B2 (da)
EP (2) EP2203464B1 (da)
AU (1) AU2008283904B2 (da)
CA (1) CA2702845C (da)
DK (1) DK2203464T3 (da)
ES (1) ES2453109T3 (da)
WO (1) WO2009021056A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8536520B2 (en) * 2007-08-06 2013-09-17 Iroa Technologies Llc Method for generation and use of isotopic patterns in mass spectral data of simple organisms
US7820963B2 (en) * 2007-08-06 2010-10-26 Metabolic Alayses, Inc. Method for generation and use of isotopic patterns in mass spectral data of simple organisms
US7820964B2 (en) * 2007-08-06 2010-10-26 Metabolic Analyses, Inc Method for generation and use of stable isotope patterns in mass spectral data
US8969251B2 (en) * 2007-10-02 2015-03-03 Methabolic Analyses, Inc. Generation and use of isotopic patterns in mass spectral phenotypic comparison of organisms
EP2798658B1 (en) * 2011-12-30 2017-03-01 DH Technologies Development Pte. Ltd. Systems and methods for sequencing peptides by mass spectrometry
US10591448B2 (en) 2015-04-14 2020-03-17 Waters Technologies Corporation Structural elucidation of isotopically labeled analytes
EP3586137A4 (en) * 2017-02-24 2020-11-04 Iroa Technologies, LLC IROA METABOLOMIC WORKFLOW FOR IMPROVED ACCURACY, IDENTIFICATION AND QUANTIFICATION
EP3811075B1 (en) * 2018-06-22 2025-07-16 Iroa Technologies, LLC Method to correct ion source inefficiencies making sample-to-sample normalization possible
EP4195237A4 (en) * 2020-08-07 2024-10-02 Shimadzu Corporation METHOD FOR CORRECTING MACHINE DIFFERENCES FOR MASS SPECTROMETRY APPARATUS

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5087815A (en) * 1989-11-08 1992-02-11 Schultz J Albert High resolution mass spectrometry of recoiled ions for isotopic and trace elemental analysis
DE69133313T2 (de) * 1990-03-16 2004-07-01 The United States Of America, Represented By The Secretary, U.S. Department Of Commerce Verwendung von Nitroxiden und Oxazolidinen zum Schutz ionisierender Strahlung und oxidativem Stress
US5912178A (en) * 1994-02-16 1999-06-15 Wisconsin Alumni Research Foundation Passive measurement of isotopes to monitor health
AU745236B2 (en) * 1997-02-14 2002-03-14 George Washington University, The An assay for the measurement of DNA synthesis rates
US6790673B1 (en) 1998-01-29 2004-09-14 Duquesne University Of The Holy Ghost Speciated isotope dilution mass spectrometry of reactive species and related methods
US6764817B1 (en) * 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses
US6391649B1 (en) * 1999-05-04 2002-05-21 The Rockefeller University Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy
US7368710B2 (en) * 2000-02-09 2008-05-06 Xceleron Limited Sample preparation method
DK1358458T3 (da) 2000-10-19 2012-06-18 Target Discovery Inc Massedefektmærkning til bestemmelse af oligomersekvenser
US7045296B2 (en) * 2001-05-08 2006-05-16 Applera Corporation Process for analyzing protein samples
JP3615182B2 (ja) * 2001-11-26 2005-01-26 株式会社東芝 光近接効果補正方法及び光近接効果補正システム
JP4160558B2 (ja) * 2002-08-22 2008-10-01 アプレラ コーポレイション 結果主導型ストラテジーを利用して生体分子を特徴付けるための方法
JP2006522340A (ja) 2003-04-02 2006-09-28 メルク　エンド　カムパニー　インコーポレーテッド 質量分析データの分析法
JP2007503001A (ja) 2003-05-15 2007-02-15 エレクトロフォレティクス リミテッド 質量分析法
AU2004256368B2 (en) * 2003-07-11 2010-08-05 Tatiana A. Egorova-Zachernyuk Compositions and methods for stable isotope labelling of biological compounds
JP4348452B2 (ja) 2003-12-16 2009-10-21 独立行政法人産業技術総合研究所 酸化ストレスマーカー及びその測定法
WO2006096704A2 (en) * 2005-03-07 2006-09-14 Invitrogen Corporation Isotopically-labeled proteome standards
US7465276B2 (en) * 2005-11-30 2008-12-16 Wisconsin Alumni Research Foundation Identification of disease characteristics using isotope ratios in breath
WO2007078835A2 (en) * 2005-12-15 2007-07-12 George Mason University Biomarker isolation and use thereof to characterize physiological state
US7653496B2 (en) 2006-02-02 2010-01-26 Agilent Technologies, Inc. Feature selection in mass spectral data
US7820964B2 (en) * 2007-08-06 2010-10-26 Metabolic Analyses, Inc Method for generation and use of stable isotope patterns in mass spectral data
US7820963B2 (en) 2007-08-06 2010-10-26 Metabolic Alayses, Inc. Method for generation and use of isotopic patterns in mass spectral data of simple organisms
US8536520B2 (en) * 2007-08-06 2013-09-17 Iroa Technologies Llc Method for generation and use of isotopic patterns in mass spectral data of simple organisms
US8969251B2 (en) * 2007-10-02 2015-03-03 Methabolic Analyses, Inc. Generation and use of isotopic patterns in mass spectral phenotypic comparison of organisms
DK2205342T3 (da) 2007-10-02 2014-03-03 Iroa Technologies Llc Generering og anvendelse af isotopiske mønstre i massespektrometrisk fænotypesammenligning af organismer

Also Published As

Publication number Publication date
EP2203464A4 (en) 2010-09-22
CA2702845C (en) 2015-09-22
US20110084204A1 (en) 2011-04-14
EP2647996B1 (en) 2015-06-03
CA2702845A1 (en) 2009-02-12
AU2008283904B2 (en) 2013-10-24
US8168945B2 (en) 2012-05-01
EP2203464A1 (en) 2010-07-07
US7820963B2 (en) 2010-10-26
WO2009021056A1 (en) 2009-02-12
EP2647996A1 (en) 2013-10-09
US20090039246A1 (en) 2009-02-12
EP2203464B1 (en) 2013-12-25
AU2008283904A1 (en) 2009-02-12
ES2453109T3 (es) 2014-04-04

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