BRPI0820211A2 - Métodos de espectrometria de massa maldi para analisar um analito de aerossol, para a classificação de biomateriais, uso de 2-mercapto-4,5-dimetilatiazol, e, uso de uma composição de matriz - Google Patents

Métodos de espectrometria de massa maldi para analisar um analito de aerossol, para a classificação de biomateriais, uso de 2-mercapto-4,5-dimetilatiazol, e, uso de uma composição de matriz

Info

Publication number
BRPI0820211A2
BRPI0820211A2 BRPI0820211-7A BRPI0820211A BRPI0820211A2 BR PI0820211 A2 BRPI0820211 A2 BR PI0820211A2 BR PI0820211 A BRPI0820211 A BR PI0820211A BR PI0820211 A2 BRPI0820211 A2 BR PI0820211A2
Authority
BR
Brazil
Prior art keywords
dimethylathiazole
biomaterial
mercapto
classification
analyzing
Prior art date
Application number
BRPI0820211-7A
Other languages
English (en)
Inventor
Arjan Laurens Wuijckhuijse
Charles Eliza Kientz
Carla Elisabeth Anna Maria Degenhardt-Langelaan
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of BRPI0820211A2 publication Critical patent/BRPI0820211A2/pt
Publication of BRPI0820211A8 publication Critical patent/BRPI0820211A8/pt
Publication of BRPI0820211B1 publication Critical patent/BRPI0820211B1/pt

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H01J49/0418—Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
BRPI0820211-7A 2007-11-13 2008-11-13 Methods of maldi mass spectrometry to analyze an analysis of aerosol and, for the classification of biomaterials BRPI0820211B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07120550.4 2007-11-13
EP07120550A EP2060919A1 (en) 2007-11-13 2007-11-13 MALDI matrix and MALDI method
PCT/NL2008/050721 WO2009064180A1 (en) 2007-11-13 2008-11-13 Maldi matrix and maldi method

Publications (3)

Publication Number Publication Date
BRPI0820211A2 true BRPI0820211A2 (pt) 2015-06-16
BRPI0820211A8 BRPI0820211A8 (pt) 2017-01-10
BRPI0820211B1 BRPI0820211B1 (pt) 2017-06-27

Family

ID=38786862

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0820211-7A BRPI0820211B1 (pt) 2007-11-13 2008-11-13 Methods of maldi mass spectrometry to analyze an analysis of aerosol and, for the classification of biomaterials

Country Status (10)

Country Link
US (1) US8409870B2 (pt)
EP (2) EP2060919A1 (pt)
JP (1) JP5209732B2 (pt)
KR (1) KR20100106336A (pt)
CN (1) CN101855556B (pt)
BR (1) BRPI0820211B1 (pt)
CA (1) CA2705506A1 (pt)
ES (1) ES2416183T3 (pt)
IL (1) IL205662A0 (pt)
WO (1) WO2009064180A1 (pt)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2416203B1 (en) * 2009-03-31 2023-09-13 Hoya Corporation Photochromic lens manufacturing system, photochromic lens manufacturing device, photochromic lens manufacturing program, recording medium having photochromic lens manufacturing program recorded thereupon, and photochromic lens manufacturing method
CN102531924B (zh) * 2010-12-27 2013-12-11 中国科学院化学研究所 硝酸萘乙二胺及其制备方法与应用
JP5895694B2 (ja) * 2012-05-11 2016-03-30 株式会社島津製作所 マトリックス支援レーザ脱離イオン化質量分析用マトリックス
ES2998535T3 (en) * 2014-02-07 2025-02-20 European Molecular Biology Laboratory Proteomic sample preparation using paramagnetic beads
CN104597113B (zh) * 2015-01-21 2015-12-09 华中师范大学 一种高分辨质谱成像系统图像采集半导体薄膜、制备方法及应用
WO2016142675A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Imaging guided ambient ionisation mass spectrometry
GB2551669B (en) 2015-03-06 2021-04-14 Micromass Ltd Physically guided rapid evaporative ionisation mass spectrometry ("Reims")
EP3741303A3 (en) 2015-03-06 2020-12-30 Micromass UK Limited Chemically guided ambient ionisation mass spectrometry
CA2981085A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Spectrometric analysis
WO2016142693A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited In vivo endoscopic tissue identification tool
GB2556436B (en) 2015-03-06 2022-01-26 Micromass Ltd Cell population analysis
CA2978048A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Liquid trap or separator for electrosurgical applications
US11289320B2 (en) 2015-03-06 2022-03-29 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
US11342170B2 (en) 2015-03-06 2022-05-24 Micromass Uk Limited Collision surface for improved ionisation
GB2554206B (en) 2015-03-06 2021-03-24 Micromass Ltd Spectrometric analysis of microbes
US10777397B2 (en) 2015-03-06 2020-09-15 Micromass Uk Limited Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry (“REIMS”) device
GB2553937B (en) 2015-03-06 2022-06-08 Micromass Ltd Improved ionisation of gaseous samples
GB2552602B (en) 2015-03-06 2020-12-30 Micromass Ltd Desorption electrospray ionisation mass spectrometry ("DESI-MS") analysis of swabs
EP3265823B1 (en) 2015-03-06 2020-05-06 Micromass UK Limited Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
JP6530141B2 (ja) * 2015-08-24 2019-06-12 ゼテオ テック、 エルエルシイＺｅｔｅｏ Ｔｅｃｈ， Ｌｌｃ 音響コータを用いたエアロゾル粒子のコーティング
GB201517195D0 (en) 2015-09-29 2015-11-11 Micromass Ltd Capacitively coupled reims technique and optically transparent counter electrode
CN106841373B (zh) * 2015-12-07 2020-03-10 中国科学院大连化学物理研究所 亚微米氧化碳球作为基质在maldi-ms中的应用
CN105319262A (zh) * 2015-12-07 2016-02-10 中国石油天然气集团公司 一种芳香族化合物分子组成的分析方法及其应用
WO2017178833A1 (en) 2016-04-14 2017-10-19 Micromass Uk Limited Spectrometric analysis of plants
WO2017190031A1 (en) * 2016-04-28 2017-11-02 Indiana University Research And Technology Corporation Methods and compositions for resolving components of a virus preparation
WO2018158399A1 (en) 2017-03-02 2018-09-07 Biosparq B.V. Diagnostic method and system for diagnosis
NL2018940B1 (en) 2017-05-18 2018-11-28 Biosparq B V Maldi mass spectrometry method
US11668719B2 (en) 2017-09-20 2023-06-06 The Trustees Of Indiana University Methods for resolving lipoproteins with mass spectrometry
US11232941B2 (en) 2018-01-12 2022-01-25 The Trustees Of Indiana University Electrostatic linear ion trap design for charge detection mass spectrometry
WO2019236139A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Interface for transporting ions from an atmospheric pressure environment to a low pressure environment
EP4376051A3 (en) 2018-06-04 2024-09-25 The Trustees of Indiana University Charge detection mass spectrometry with real time analysis and signal optimization
WO2019236143A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Apparatus and method for calibrating or resetting a charge detector
WO2019236141A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Apparatus and method for capturing ions in an electrostatic linear ion trap
WO2019236142A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Ion trap array for high throughput charge detection mass spectrometry
CN108896646A (zh) * 2018-07-04 2018-11-27 上海海洋大学 亲缘关系相近的海鲜的快速分类和鉴定方法
EP3884510A1 (en) 2018-11-20 2021-09-29 The Trustees of Indiana University Orbitrap for single particle mass spectrometry
US11562896B2 (en) 2018-12-03 2023-01-24 The Trustees Of Indiana University Apparatus and method for simultaneously analyzing multiple ions with an electrostatic linear ion trap
US20200355646A1 (en) * 2019-03-21 2020-11-12 C2Sense, Inc. Systems for detection of volatile ions and related methods
US11942317B2 (en) 2019-04-23 2024-03-26 The Trustees Of Indiana University Identification of sample subspecies based on particle mass and charge over a range of sample temperatures
KR102485642B1 (ko) * 2019-08-26 2023-01-06 제테오 테크, 인코포레이티드 호기를 이용한 결핵 및 기타 질병의 진단
WO2021061330A1 (en) * 2019-09-23 2021-04-01 Zeteo Tech, Inc. Systems and methods of rapid and autonomous detection of aerosol particles
US12074018B2 (en) 2019-09-23 2024-08-27 Zeteo Tech, Inc. Systems and methods of rapid and autonomous detection of aerosol particles
WO2021061650A1 (en) 2019-09-25 2021-04-01 The Trustees Of Indiana University Apparatus and method for pulsed mode charge detection mass spectrometry
KR102849777B1 (ko) 2019-10-10 2025-08-22 더 트러스티즈 오브 인디애나 유니버시티 입자들을 식별, 선택 및 정제하기 위한 시스템 및 방법
CA3165106A1 (en) 2019-12-18 2021-06-24 The Trustees Of Indiana University Mass spectrometer with charge measurement arrangement
EP4100991B1 (en) 2020-02-03 2025-01-29 The Trustees of Indiana University A charge detection mass spectrometer and related method
US12364411B2 (en) 2020-04-03 2025-07-22 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
EP4125569B1 (en) 2020-04-03 2026-05-20 Zeteo Tech Inc SYSTEM FOR DIAGNOSING RESPIRATORY DISEASES USING ANALYSIS OF EXHAUSTED AIR AND AEROSOLS
CN112162028A (zh) * 2020-09-29 2021-01-01 中国农业科学院农业质量标准与检测技术研究所 一种用于草莓组织中维生素c的质谱成像方法
JP2024518022A (ja) 2021-03-31 2024-04-24 ゼテオ テック、 インク． 充填ベッドシステムおよび方法を使用したエアロゾル化生体材料粒子の捕捉による呼吸器疾患の診断
WO2024215320A1 (en) * 2023-04-11 2024-10-17 Zeteo Tech, Inc. Systems and methods of rapid and autonomous detection of aerosol particles
CN120374399B (zh) * 2025-06-26 2025-11-21 宁波华仪宁创智能科技有限公司 基于质谱技术的单细胞代谢组学分析方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9617852D0 (en) * 1996-08-27 1996-10-09 Univ Manchester Metropolitan Micro-organism identification
NL1016887C2 (nl) * 2000-12-15 2002-06-18 Tno Werkwijze en inrichting voor het detecteren en identificeren van bio-aÙrosoldeeltjes in de lucht.
DE10238069A1 (de) 2002-08-19 2004-03-04 N.V. Nutricia MALDI-Matrix
US6943346B2 (en) * 2003-08-13 2005-09-13 Science & Engineering Services, Inc. Method and apparatus for mass spectrometry analysis of aerosol particles at atmospheric pressure
US20060261267A1 (en) 2005-05-20 2006-11-23 Agency For Science, Technology And Research Composite MALDI matrix material and methods of using it and kits thereof in MALDI

Also Published As

Publication number Publication date
KR20100106336A (ko) 2010-10-01
CN101855556A (zh) 2010-10-06
EP2210110A1 (en) 2010-07-28
BRPI0820211A8 (pt) 2017-01-10
JP5209732B2 (ja) 2013-06-12
CN101855556B (zh) 2015-04-29
US8409870B2 (en) 2013-04-02
WO2009064180A1 (en) 2009-05-22
JP2011503605A (ja) 2011-01-27
EP2060919A1 (en) 2009-05-20
BRPI0820211B1 (pt) 2017-06-27
CA2705506A1 (en) 2009-05-22
ES2416183T3 (es) 2013-07-30
IL205662A0 (en) 2010-11-30
EP2210110B1 (en) 2013-03-27
US20120018628A1 (en) 2012-01-26

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25A Requested transfer of rights approved

Owner name: BIOSPARQ B.V. (NL)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2696 DE 06-09-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.