DK2210081T3 - Fremgangsmåde til identificering og håndtering af partikler - Google Patents

Fremgangsmåde til identificering og håndtering af partikler Download PDF

Info

Publication number
DK2210081T3
DK2210081T3 DK08844732.1T DK08844732T DK2210081T3 DK 2210081 T3 DK2210081 T3 DK 2210081T3 DK 08844732 T DK08844732 T DK 08844732T DK 2210081 T3 DK2210081 T3 DK 2210081T3
Authority
DK
Denmark
Prior art keywords
identifying
handling particles
handling
particles
Prior art date
Application number
DK08844732.1T
Other languages
English (en)
Inventor
Gianni Medoro
Stefano Gianni
Nicolò Manaresi
Original Assignee
Menarini Silicon Biosystems Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Silicon Biosystems Spa filed Critical Menarini Silicon Biosystems Spa
Application granted granted Critical
Publication of DK2210081T3 publication Critical patent/DK2210081T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012—Red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497—Particle shape

Landscapes

  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
DK08844732.1T 2007-10-29 2008-10-28 Fremgangsmåde til identificering og håndtering af partikler DK2210081T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000771A ITTO20070771A1 (it) 2007-10-29 2007-10-29 Metodo e apparato per la identificazione e manipolazione di particelle
PCT/IB2008/002873 WO2009056941A2 (en) 2007-10-29 2008-10-28 Method and apparatus for the identification and handling of particles

Publications (1)

Publication Number Publication Date
DK2210081T3 true DK2210081T3 (da) 2021-06-28

Family

ID=40314173

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08844732.1T DK2210081T3 (da) 2007-10-29 2008-10-28 Fremgangsmåde til identificering og håndtering af partikler

Country Status (8)

Country Link
US (2) US9310287B2 (da)
EP (1) EP2210081B1 (da)
JP (1) JP5324590B2 (da)
CN (1) CN101918809B (da)
DK (1) DK2210081T3 (da)
ES (1) ES2879391T3 (da)
IT (1) ITTO20070771A1 (da)
WO (1) WO2009056941A2 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITBO20040420A1 (it) 2004-07-07 2004-10-07 Type S R L Macchina per taglio e formatura di piattine metalliche
ITBO20050481A1 (it) 2005-07-19 2007-01-20 Silicon Biosystems S R L Metodo ed apparato per la manipolazione e/o l'individuazione di particelle
ITBO20050646A1 (it) * 2005-10-26 2007-04-27 Silicon Biosystem S R L Metodo ed apparato per la caratterizzazione ed il conteggio di particelle
ITTO20060226A1 (it) 2006-03-27 2007-09-28 Silicon Biosystem S P A Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche
ITTO20070771A1 (it) 2007-10-29 2009-04-30 Silicon Biosystems Spa Metodo e apparato per la identificazione e manipolazione di particelle
US10895575B2 (en) 2008-11-04 2021-01-19 Menarini Silicon Biosystems S.P.A. Method for identification, selection and analysis of tumour cells
IT1391619B1 (it) 2008-11-04 2012-01-11 Silicon Biosystems Spa Metodo per l'individuazione, selezione e analisi di cellule tumorali
PT2408562T (pt) 2009-03-17 2018-06-06 Menarini Silicon Biosystems Spa Dispositivo microfluídico para isolamento de células
IT1403518B1 (it) 2010-12-22 2013-10-31 Silicon Biosystems Spa Dispositivo microfluidico per la manipolazione di particelle
DE102011075809A1 (de) * 2011-05-13 2012-11-15 Carl Zeiss Microimaging Gmbh Verfahren und Vorrichtung zum Festlegen eines z-Bereiches in einer Probe, in dem ein z-Stapel der Probe mittels eines Mikroskops aufzunehmen ist
US9354155B2 (en) * 2011-05-31 2016-05-31 Bio-Rad Laboratories, Inc. Cell counting systems and methods
ITTO20110990A1 (it) 2011-10-28 2013-04-29 Silicon Biosystems Spa Metodo ed apparato per l'analisi ottica di particelle a basse temperature
ITBO20110766A1 (it) 2011-12-28 2013-06-29 Silicon Biosystems Spa Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico
JP6767981B2 (ja) * 2015-08-26 2020-10-14 倉敷紡績株式会社 細胞測定方法
US10732092B2 (en) * 2015-12-22 2020-08-04 University Of Maryland, College Park Analysis of single cell mechanical phenotyping for metastatic detection
WO2019232473A2 (en) * 2018-05-31 2019-12-05 Berkeley Lights, Inc. Automated detection and characterization of micro-objects in microfluidic devices
AT527149A1 (de) * 2023-04-21 2024-11-15 Anton Paar Gmbh Vorrichtung und Verfahren zum Charakterisieren einer Partikelprobe

Family Cites Families (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58211272A (ja) 1982-06-02 1983-12-08 Hitachi Ltd 閾値決定法
US5252493A (en) 1986-09-22 1993-10-12 Nippon Telegraph And Telephone Corporation Laser magnetic immunoassay method and apparatus therefor
DE3931851A1 (de) 1989-09-23 1991-04-11 Heinrich Joern Dipl Chem Computergesteuerter potentialdifferenz-leitfaehigkeitsscanner fuer traegerfreie elektrophorese
EP0791659A3 (en) 1989-11-13 1997-09-17 Children's Medical Center Corporation Antigen specific separation of nucleated fetal cells in non-invasive detection of fetal DNA
US5641628A (en) * 1989-11-13 1997-06-24 Children's Medical Center Corporation Non-invasive method for isolation and detection of fetal DNA
GB8926781D0 (en) 1989-11-27 1990-01-17 Nat Res Dev Identification of micro-organisms
US5840482A (en) 1990-10-10 1998-11-24 The Regents Of The University Of California Y chromosome specific nucleic acid probe and method for determining the Y chromosome in situ
US6149789A (en) 1990-10-31 2000-11-21 Fraunhofer Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Process for manipulating microscopic, dielectric particles and a device therefor
DE4214320C1 (da) 1992-05-04 1993-06-03 Erwin Halder Kg, 7958 Laupheim, De
JP3165309B2 (ja) * 1993-12-22 2001-05-14 株式会社日立製作所 粒子画像解析装置
DE19500660B4 (de) 1994-12-10 2007-12-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung und Verfahren zur Manipulation mikroskopisch kleiner Partikel sowie deren Verwendung
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5888370A (en) 1996-02-23 1999-03-30 Board Of Regents, The University Of Texas System Method and apparatus for fractionation using generalized dielectrophoresis and field flow fractionation
US5945281A (en) 1996-02-02 1999-08-31 Becton, Dickinson And Company Method and apparatus for determining an analyte from a sample fluid
GB9615775D0 (en) 1996-07-26 1996-09-04 British Tech Group Apparatus and method for characterising particles using dielectrophoresis
JP2002503334A (ja) 1996-09-04 2002-01-29 テクニカル ユニバーシティ オブ デンマーク 粒子の分離と分析用のマイクロフローシステム
AU9792098A (en) 1997-10-06 1999-04-27 California Institute Of Technology Electrostatic particle transportation
ATE400358T1 (de) 1997-12-24 2008-07-15 Cepheid Vorrichtung und verfahren zur lyse
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
US6203683B1 (en) 1998-11-09 2001-03-20 Princeton University Electrodynamically focused thermal cycling device
US6294063B1 (en) 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
US20030228565A1 (en) * 2000-04-26 2003-12-11 Cytokinetics, Inc. Method and apparatus for predictive cellular bioinformatics
US6942776B2 (en) 1999-05-18 2005-09-13 Silicon Biosystems S.R.L. Method and apparatus for the manipulation of particles by means of dielectrophoresis
IT1309430B1 (it) 1999-05-18 2002-01-23 Guerrieri Roberto Metodo ed apparato per la manipolazione di particelle per mezzo delladielettroforesi
WO2000069525A1 (en) 1999-05-19 2000-11-23 Qualcomm Incorporated Apparatus and method for interfacing personal electronics to exercise equipment
AU780073B2 (en) 1999-05-28 2005-02-24 Cepheid Apparatus and method for cell disruption
IL147793A0 (en) * 1999-08-05 2002-08-14 Cellomics Inc Optical system analysis of cells
US6824664B1 (en) 1999-11-04 2004-11-30 Princeton University Electrode-less dielectrophorises for polarizable particles
EP1716926A3 (en) 2000-04-13 2007-08-29 Wako Pure Chemical Industries Ltd Electrode for dielectrophoretic apparatus, dielectrophoretic apparatus, method for manufacturing the same, and method for separating substances using the electrode or dielectrophoretic apparatus
US6899849B2 (en) 2000-07-28 2005-05-31 The Regents Of The University Of California Integrated sensor
WO2002012896A1 (en) 2000-08-08 2002-02-14 Aviva Biosciences Corporation Methods for manipulating moieties in microfluidic systems
US6833542B2 (en) 2000-11-13 2004-12-21 Genoptix, Inc. Method for sorting particles
AU2002223503A1 (en) 2000-11-24 2002-06-03 Novo-Nordisk A/S Decondenser unit
DE10059152C2 (de) 2000-11-29 2003-03-27 Evotec Ag Mikrosystem zur dielektrischen und optischen Manipulierung von Partikeln
US6764583B2 (en) 2000-12-13 2004-07-20 The Regents Of The University Of California Using impedance measurements for detecting pathogens trapped in an electric field
JP3868788B2 (ja) 2001-10-15 2007-01-17 株式会社東芝 電気泳動表示装置
JP2002311461A (ja) 2001-04-17 2002-10-23 Sharp Corp 表示素子
ITTO20010411A1 (it) 2001-05-02 2002-11-02 Silicon Biosystems S R L Metodo e dispositivo per l'esecuzione di test e saggi ad alta processivita' ed alto valore biologico su cellule e/o composti.
US20050009101A1 (en) 2001-05-17 2005-01-13 Motorola, Inc. Microfluidic devices comprising biochannels
US20030073110A1 (en) 2001-07-03 2003-04-17 Masaharu Aritomi Method for isolating nucleic acid and a cartridge for chemical reaction and for nucleic acid isolation
ITTO20010801A1 (it) 2001-08-07 2003-02-07 Silicon Biosystems S R L Metodo e dispositivo per analisi biomolecolari integrate.
JP2005501296A (ja) 2001-08-23 2005-01-13 コーニンクレッカ　フィリップス　エレクトロニクス　エヌ　ヴィ 電気泳動表示装置
KR20040047971A (ko) 2001-10-26 2004-06-05 이뮤니베스트 코포레이션 동일 샘플상에서의 광범위 핵산 및 이의 형태학적 특질에대한 다중 매개변수 분석법
US7163612B2 (en) 2001-11-26 2007-01-16 Keck Graduate Institute Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like
JP3845583B2 (ja) 2002-01-09 2006-11-15 株式会社東芝 電気泳動表示装置及びその製造方法
DE10203636B4 (de) 2002-01-30 2004-02-12 Testo Gmbh & Co Vorrichtung zum Nachweis von Partikeln in einem Fluid
US7147763B2 (en) 2002-04-01 2006-12-12 Palo Alto Research Center Incorporated Apparatus and method for using electrostatic force to cause fluid movement
AU2003277853A1 (en) 2002-06-24 2004-01-06 Fluidigm Corporation Recirculating fluidic network and methods for using the same
US20040011652A1 (en) 2002-07-16 2004-01-22 Bressler Vincent Edward Separation of particles using multiple conductive layers
US6911132B2 (en) 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
US7329545B2 (en) 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
CA2500392C (en) * 2002-09-27 2012-11-27 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US6888721B1 (en) 2002-10-18 2005-05-03 Atec Corporation Electrohydrodynamic (EHD) thin film evaporator with splayed electrodes
US7932098B2 (en) 2002-10-31 2011-04-26 Hewlett-Packard Development Company, L.P. Microfluidic system utilizing thin-film layers to route fluid
WO2004061085A2 (en) 2002-12-30 2004-07-22 The Regents Of The University Of California Methods and apparatus for pathogen detection and analysis
US7338637B2 (en) 2003-01-31 2008-03-04 Hewlett-Packard Development Company, L.P. Microfluidic device with thin-film electronic devices
US6814222B2 (en) 2003-02-03 2004-11-09 Fki Logistex Automation Inc. Narrow belt non-pneumatically actuated accumulation conveyor
DE10304653B4 (de) * 2003-02-05 2005-01-27 Evotec Technologies Gmbh Mehrparametrige Detektion in einem fluidischen Mikrosystem
GB0303305D0 (en) 2003-02-12 2003-03-19 Secr Defence Apparatus for collecting particles
WO2004074913A2 (en) * 2003-02-19 2004-09-02 Bioarray Solutions Ltd. A dynamically configurable electrode formed of pixels
DK2959774T3 (da) * 2003-03-28 2019-05-13 Inguran Llc Fremgangsmåde til kryokonservering af sædceller
GB0307684D0 (en) * 2003-04-02 2003-05-07 Amersham Biosciences Uk Ltd Determining cell cycle phase data
US20050181429A1 (en) 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20070015289A1 (en) 2003-09-19 2007-01-18 Kao H P Dispenser array spotting
US7476360B2 (en) 2003-12-09 2009-01-13 Genefluidics, Inc. Cartridge for use with electrochemical sensor
US7160425B2 (en) 2004-03-25 2007-01-09 Hewlett-Packard Development Company, L.P. Cell transporter for a biodevice
DE102004017474A1 (de) 2004-04-08 2005-10-27 Evotec Technologies Gmbh Messeinrichtung zur Impedanzspektroskopie und zugehöriges Messverfahren
ITBO20040420A1 (it) 2004-07-07 2004-10-07 Type S R L Macchina per taglio e formatura di piattine metalliche
EP1796768A2 (en) 2004-07-12 2007-06-20 Bioservice S.p.A. Tracheostomy apparatus
DE102004047752B3 (de) 2004-09-30 2006-01-26 Infineon Technologies Ag Halbleiterbauteil mit Temperatursensor
US7113625B2 (en) * 2004-10-01 2006-09-26 U.S. Pathology Labs, Inc. System and method for image analysis of slides
US20060177815A1 (en) 2004-11-29 2006-08-10 The Regents Of The University Of California Dielectrophoretic particle sorter
JP4507207B2 (ja) 2004-12-03 2010-07-21 株式会社ダ・ビンチ 磁性対流熱循環ポンプ
US20060171846A1 (en) 2005-01-10 2006-08-03 Marr David W M Microfluidic systems incorporating integrated optical waveguides
EP1861509B1 (en) 2005-03-14 2015-09-09 Janssen Diagnostics, LLC A method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells
DE102005012128A1 (de) 2005-03-16 2006-09-21 Evotec Technologies Gmbh Mikrofluidisches System und zugehöriges Ansteuerverfahren
US20070026413A1 (en) * 2005-07-29 2007-02-01 Mehmet Toner Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20060223178A1 (en) * 2005-04-05 2006-10-05 Tom Barber Devices and methods for magnetic enrichment of cells and other particles
US20070026415A1 (en) * 2005-07-29 2007-02-01 Martin Fuchs Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US7998328B2 (en) 2005-06-27 2011-08-16 Cfd Research Corporation Method and apparatus for separating particles by dielectrophoresis
JP2007017163A (ja) 2005-07-05 2007-01-25 Sumitomo Chemical Co Ltd 粒状製品の評価方法
ITBO20050481A1 (it) 2005-07-19 2007-01-20 Silicon Biosystems S R L Metodo ed apparato per la manipolazione e/o l'individuazione di particelle
EP1928603A1 (en) 2005-09-02 2008-06-11 California Institute Of Technology Method and apparatus for the mechanical actuation of valves in fluidic devices
US20070059683A1 (en) 2005-09-15 2007-03-15 Tom Barber Veterinary diagnostic system
US7518723B2 (en) * 2005-09-19 2009-04-14 Jmar Technologies, Inc. Systems and methods for detecting radiation, biotoxin, chemical, and biological warfare agents using a multiple angle light scattering (MALS) instrument
WO2007044888A2 (en) * 2005-10-11 2007-04-19 The Johns Hopkins Univerisity Microfluidic device and method for high-throughput cellular gradient and dose response studies
ITBO20050643A1 (it) 2005-10-24 2007-04-25 Si Bio S R L Metodo ed apparato per la manipolazione di particelle in soluzioni conduttive
ITBO20050646A1 (it) 2005-10-26 2007-04-27 Silicon Biosystem S R L Metodo ed apparato per la caratterizzazione ed il conteggio di particelle
GB2435925A (en) * 2006-03-09 2007-09-12 Cytokinetics Inc Cellular predictive models for toxicities
US8112247B2 (en) * 2006-03-24 2012-02-07 International Business Machines Corporation Resource adaptive spectrum estimation of streaming data
ITTO20060226A1 (it) * 2006-03-27 2007-09-28 Silicon Biosystem S P A Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche
ITTO20060273A1 (it) 2006-04-12 2007-10-13 Silicon Biosystem S P A Metodi ed apparati per la selezione e/o il processamento di particellle, in particolare per la lisi selettiva e/o ottimizzata di cellule
US20080124721A1 (en) 2006-06-14 2008-05-29 Martin Fuchs Analysis of rare cell-enriched samples
EP2548972A1 (en) 2006-06-14 2013-01-23 Verinata Health, Inc Methods for the diagnosis of fetal abnormalities
KR100818274B1 (ko) * 2006-09-05 2008-04-01 삼성전자주식회사 미세유동 시스템 제어장치 및 그 방법, 및 미세유동 시스템
EP2412828B1 (en) 2007-03-13 2013-06-05 Amgen Inc. K-ras and B-raf mutations and anti-EGFr antibody therapy
US20100233694A1 (en) 2007-04-16 2010-09-16 On-O-ity, Inc Devices and methods for diagnosing, prognosing, or theranosing a condition by enriching rare cells
ITBO20070588A1 (it) 2007-08-13 2009-02-14 Silicon Biosystems Spa Metodo per legare uno strato di silicone ad un substrato di polimero metacrilico
ITTO20070771A1 (it) 2007-10-29 2009-04-30 Silicon Biosystems Spa Metodo e apparato per la identificazione e manipolazione di particelle
ES2640216T3 (es) 2007-12-07 2017-11-02 Miltenyi Biotec Gmbh Sistemas y métodos para procesamiento de células
IT1391619B1 (it) * 2008-11-04 2012-01-11 Silicon Biosystems Spa Metodo per l'individuazione, selezione e analisi di cellule tumorali
PT2408562T (pt) * 2009-03-17 2018-06-06 Menarini Silicon Biosystems Spa Dispositivo microfluídico para isolamento de células
GB0910330D0 (en) 2009-06-16 2009-07-29 Univ Leiden A biological microfluidics chip and related methods
ITTO20110990A1 (it) 2011-10-28 2013-04-29 Silicon Biosystems Spa Metodo ed apparato per l'analisi ottica di particelle a basse temperature
ITBO20110766A1 (it) 2011-12-28 2013-06-29 Silicon Biosystems Spa Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico

Also Published As

Publication number Publication date
JP2011501205A (ja) 2011-01-06
WO2009056941A2 (en) 2009-05-07
ES2879391T3 (es) 2021-11-22
EP2210081A2 (en) 2010-07-28
ITTO20070771A1 (it) 2009-04-30
US20160202173A1 (en) 2016-07-14
CN101918809A (zh) 2010-12-15
CN101918809B (zh) 2014-04-16
US9310287B2 (en) 2016-04-12
EP2210081B1 (en) 2021-04-21
JP5324590B2 (ja) 2013-10-23
US20100331205A1 (en) 2010-12-30
US10648897B2 (en) 2020-05-12
WO2009056941A3 (en) 2009-09-17

Similar Documents

Publication Publication Date Title
DK1909965T3 (da) Fremgangsmåde og indretning til manipulation af partikler
DK2163094T3 (da) Fremgangsmåde og system til monitorering af et miljø
DK3081315T3 (da) Fremgangsmåde og system til sortering af fødevarer
DK3045545T3 (da) Fremgangsmåde og indretning til karakterisering og tælling af partikler, især biologiske partikler
DK2220450T4 (da) Transportkølesystem og fremgangsmåde til anvendelse deraf
DK2079355T3 (da) Fremgangsmåde og system til brilleordination
DK2147315T3 (da) Diabetesrelaterede biomarkører og fremgangsmåder til anvendelse deraf
DK2342858T3 (da) Fremgangsmåde og apparat til tilvejebringelse af redundansversioner
DK2131939T3 (da) Filteranordning og fremgangsmåde
BRPI0719397A2 (pt) Metódo e aparelho de separação
DK3702371T3 (da) Anti-FGFR3-antistoffer og fremgangsmåder ved anvendelse af disse
DK2070843T3 (da) Fremgangsmåde og indretning til transport af objekter
BRPI0819816A2 (pt) método e aparelho de revestimento automatizado
DK2300137T3 (da) Fremgangsmåde og indretning til aflæsning af en emulsion
DK2142063T3 (da) Redskab og fremgangsmåde til vedligeholdelse af gulve
FI20075897L (fi) Menetelmä ja järjestely tiedonhakutulosten käsittelemiseksi
DK1977611T3 (da) Håndtering af medieindhold
DK2081669T3 (da) Fremgangsmåde og anordning til fremstilling af granulater
DK2167868T3 (da) Fremgangsmåde og system til minimering af lysforurening
DK2461265T3 (da) Anordning og fremgangsmåde til håndtering af følsomme data
DK2062067T3 (da) Fremgangsmåde og anordning til sporing af en genstand
BRPI0816907A2 (pt) Método e dispositivo
DK2195548T3 (da) Leje, og fremgangsmåde og håndtering af lejet
DK1816096T3 (da) System og fremgangsmåde til håndtering af genanvendelige kasser
DK2155591T3 (da) Fremgangsmåde og anordning til stabling af pladeformede legemer